199527

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 35891..36479 Replicon plasmid pSYSA
Accession NZ_CP073020
Organism Synechocystis sp. PCC 6803

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag KBZ93_RS17890 Protein ID WP_011153708.1
Coordinates 36189..36479 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KBZ93_RS17885 Protein ID WP_011153707.1
Coordinates 35891..36178 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KBZ93_RS17855 (KBZ93_17860) 31037..31369 - 333 WP_011153703.1 DUF433 domain-containing protein -
KBZ93_RS17860 (KBZ93_17865) 31422..31595 + 174 WP_158299052.1 hypothetical protein -
KBZ93_RS17865 (KBZ93_17870) 31641..31790 - 150 WP_158299053.1 hypothetical protein -
KBZ93_RS17870 (KBZ93_17875) 31822..32097 + 276 WP_011153704.1 hypothetical protein -
KBZ93_RS17875 (KBZ93_17880) 32289..32483 + 195 WP_011153705.1 hypothetical protein -
KBZ93_RS17880 (KBZ93_17885) 32647..35523 + 2877 WP_011153706.1 DUF3854 domain-containing protein -
KBZ93_RS17885 (KBZ93_17890) 35891..36178 - 288 WP_011153707.1 putative addiction module antidote protein Antitoxin
KBZ93_RS17890 (KBZ93_17895) 36189..36479 - 291 WP_011153708.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KBZ93_RS17895 (KBZ93_17900) 36597..36848 + 252 WP_011153709.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
KBZ93_RS17900 (KBZ93_17905) 36839..37201 + 363 WP_011153710.1 type II toxin-antitoxin system PemK/MazF family toxin -
KBZ93_RS17905 (KBZ93_17910) 37267..37521 - 255 WP_011153711.1 DUF1819 family protein -
KBZ93_RS17910 (KBZ93_17915) 37554..38138 - 585 WP_011153712.1 hypothetical protein -
KBZ93_RS17915 (KBZ93_17920) 38131..38712 - 582 WP_011153713.1 hypothetical protein -
KBZ93_RS17920 (KBZ93_17925) 40245..40514 - 270 WP_011153715.1 putative toxin-antitoxin system toxin component, PIN family -
KBZ93_RS17925 (KBZ93_17930) 40637..41368 - 732 WP_011153716.1 DUF4386 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Non-Mobilizable plasmid - - 1..103307 103307


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Uncharacterized protein HI1420

(7-92)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10872.47 Da        Isoelectric Point: 9.8740

>T199527 WP_011153708.1 NZ_CP073020:c36479-36189 [Synechocystis sp. PCC 6803]
MIEIRQTETYARWFKSLRDCQAKARIDIRIRRLSLVNAGDVKSVGGGVSELRINYGPGYRIYFTQQGEQLIILLAGGDKQ
TQSNDITIARDLAKEL

Download         Length: 291 bp

>T199527 NZ_CP097371:c133378-133073 [Escherichia coli]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTTCAGAGTGACATTATTGACAC
GCCCGGGCGACGGATGGTGATCCCCCTGGCCAGTGCCCGCCTGCTGTCAGACAAAGTCTCCCGTGAGCTTTACCCGGTGG
TGCATGTCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAAGAAGTG
GCTGATCTCAGTCACCGCGAAAATGACATCAAAAACGCCATTAACCTGATGTTCTGGGGAATATAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10229.81 Da        Isoelectric Point: 4.3566

>AT199527 WP_011153707.1 NZ_CP073020:c36178-35891 [Synechocystis sp. PCC 6803]
METLKTIPWDAADHLESREDMAAYLEAALEEGDPALILVALGDIARSKGMTLIAKETGLGRESLYKALSANGNPEFVTVL
KVMEALGLRLQATTL

Download         Length: 288 bp

>AT199527 NZ_CP097371:c133598-133380 [Escherichia coli]
ATGAAGCAGCGTATTACAGTGACAGTTGACAGCGACAGCTATCAATTGCTCAAGGCATATGATGTCAATATCTCCGGTCT
GGTAAGCACAACCATGCAGAATGAAGCCCGTCGTCTGCGTGCCGAACGCTGGAAAGCGGAAAATCAGGAAGGGATGGCTG
AGGTCGCCCGGTTTATTGAAATGAACGGCTCTTTTGCCGATGAGAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References