285538

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2696251..2696576 Replicon chromosome
Accession NZ_LN680001
Organism Bacillus subtilis strain BS34A

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag VV28_RS13515 Protein ID WP_004398662.1
Coordinates 2696251..2696430 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2696354..2696576 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VV28_RS21880 2695477..2695614 - 138 WP_003229934.1 hypothetical protein -
VV28_RS13510 2695656..2696105 - 450 WP_003229933.1 phage portal protein -
VV28_RS13515 2696251..2696430 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- 2696354..2696576 - 223 NuclAT_0 - Antitoxin
- 2696354..2696576 - 223 NuclAT_0 - Antitoxin
- 2696354..2696576 - 223 NuclAT_0 - Antitoxin
- 2696354..2696576 - 223 NuclAT_0 - Antitoxin
VV28_RS22485 2696810..2696899 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
VV28_RS13520 2697153..2697596 - 444 WP_003229930.1 phage tail tube protein -
VV28_RS13525 2697599..2698999 - 1401 WP_003229929.1 phage tail sheath family protein -
VV28_RS13530 2699000..2699191 - 192 WP_010886574.1 hypothetical protein -
VV28_RS13535 2699188..2699625 - 438 WP_003229927.1 hypothetical protein -
VV28_RS13540 2699638..2700141 - 504 WP_003246050.1 HK97 gp10 family phage protein -
VV28_RS13545 2700138..2700500 - 363 WP_003229925.1 YqbH/XkdH family protein -
VV28_RS13550 2700497..2700892 - 396 WP_004398566.1 DUF3199 family protein -
VV28_RS13555 2700896..2701207 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2663501..2717254 53753
inside Prophage - - 2665764..2717254 51490


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T285538 WP_004398662.1 NZ_LN680001:2696251-2696430 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

Antitoxin


Download         Length: 223 bp

>AT285538 NZ_LN680001:c2696576-2696354 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References