Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2696249..2696574 Replicon chromosome
Accession NZ_LN649259
Organism Bacillus subtilis strain BS49

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag VV34_RS14265 Protein ID WP_004398662.1
Coordinates 2696249..2696428 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2696352..2696574 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VV34_RS23070 2695475..2695612 - 138 WP_003229934.1 hypothetical protein -
VV34_RS14260 2695654..2696103 - 450 WP_003229933.1 phage portal protein -
VV34_RS14265 2696249..2696428 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- 2696352..2696574 - 223 NuclAT_0 - Antitoxin
- 2696352..2696574 - 223 NuclAT_0 - Antitoxin
- 2696352..2696574 - 223 NuclAT_0 - Antitoxin
- 2696352..2696574 - 223 NuclAT_0 - Antitoxin
VV34_RS23695 2696808..2696897 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
VV34_RS14275 2697151..2697594 - 444 WP_003229930.1 phage tail tube protein -
VV34_RS14280 2697597..2698997 - 1401 WP_003229929.1 phage tail sheath family protein -
VV34_RS14285 2698998..2699189 - 192 WP_010886574.1 hypothetical protein -
VV34_RS14290 2699186..2699623 - 438 WP_003229927.1 hypothetical protein -
VV34_RS14295 2699636..2700139 - 504 WP_003246050.1 HK97 gp10 family phage protein -
VV34_RS14300 2700136..2700498 - 363 WP_003229925.1 YqbH/XkdH family protein -
VV34_RS14305 2700495..2700890 - 396 WP_004398566.1 DUF3199 family protein -
VV34_RS14310 2700894..2701205 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2663499..2717252 53753


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T285517 WP_004398662.1 NZ_LN649259:2696249-2696428 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

Antitoxin


Download         Length: 223 bp

>AT285517 NZ_LN649259:c2696574-2696352 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References