Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 1619869..1620195 Replicon chromosome
Accession NZ_CP125762
Organism Bacillus subtilis strain KRS015

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag QLQ05_RS08545 Protein ID WP_004398662.1
Coordinates 1620016..1620195 (-) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 1619869..1620092 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLQ05_RS08495 (1615221) 1615221..1615533 + 313 Protein_1658 YqbF domain-containing protein -
QLQ05_RS08500 (1615537) 1615537..1615935 + 399 Protein_1659 DUF3199 family protein -
QLQ05_RS08505 (1615932) 1615932..1616296 + 365 Protein_1660 YqbH/XkdH family protein -
QLQ05_RS08510 (1616293) 1616293..1616797 + 505 Protein_1661 HK97 gp10 family phage protein -
QLQ05_RS08515 (1616810) 1616810..1617247 + 438 WP_003229927.1 hypothetical protein -
QLQ05_RS08520 (1617244) 1617244..1617435 + 192 WP_010886574.1 hypothetical protein -
QLQ05_RS08525 (1617436) 1617436..1618838 + 1403 Protein_1664 phage tail sheath family protein -
QLQ05_RS08530 (1618841) 1618841..1619286 + 446 Protein_1665 phage tail tube protein -
QLQ05_RS08535 (1619507) 1619507..1619605 - 99 WP_283296538.1 putative holin-like toxin -
QLQ05_RS08540 (1619586) 1619586..1619645 - 60 Protein_1667 hypothetical protein -
- (1619869) 1619869..1620092 + 224 NuclAT_1 - Antitoxin
- (1619869) 1619869..1620092 + 224 NuclAT_1 - Antitoxin
- (1619869) 1619869..1620092 + 224 NuclAT_1 - Antitoxin
- (1619869) 1619869..1620092 + 224 NuclAT_1 - Antitoxin
QLQ05_RS08545 (1620016) 1620016..1620195 - 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
QLQ05_RS08550 (1620343) 1620343..1620792 + 450 WP_003229933.1 phage portal protein -
QLQ05_RS08555 (1620829) 1620829..1620972 + 144 WP_283296297.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 1551114..1662348 111234


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T282352 WP_004398662.1 NZ_CP125762:c1620195-1620016 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

Antitoxin


Download         Length: 224 bp

>AT282352 NZ_CP125762:1619869-1620092 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAAACTACCCTTTAATA
GGAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References