Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 1571792..1572117 Replicon chromosome
Accession NZ_CP125762
Organism Bacillus subtilis strain KRS015

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag QLQ05_RS08195 Protein ID WP_004398662.1
Coordinates 1571938..1572117 (-) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 1571792..1572014 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLQ05_RS08150 (1567161) 1567161..1567472 + 312 WP_003229923.1 YqbF domain-containing protein -
QLQ05_RS08155 (1567476) 1567476..1567871 + 396 WP_004398566.1 DUF3199 family protein -
QLQ05_RS08160 (1567868) 1567868..1568230 + 363 WP_003229925.1 YqbH/XkdH family protein -
QLQ05_RS08165 (1568227) 1568227..1568730 + 504 WP_003246050.1 HK97 gp10 family phage protein -
QLQ05_RS08170 (1568743) 1568743..1569180 + 438 WP_003229927.1 hypothetical protein -
QLQ05_RS08175 (1569177) 1569177..1569368 + 192 WP_010886574.1 hypothetical protein -
QLQ05_RS08180 (1569369) 1569369..1570769 + 1401 WP_003229929.1 phage tail sheath family protein -
QLQ05_RS08185 (1570772) 1570772..1571215 + 444 WP_003229930.1 phage tail tube protein -
QLQ05_RS08190 (1571469) 1571469..1571558 - 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
- (1571792) 1571792..1572014 + 223 NuclAT_0 - Antitoxin
- (1571792) 1571792..1572014 + 223 NuclAT_0 - Antitoxin
- (1571792) 1571792..1572014 + 223 NuclAT_0 - Antitoxin
- (1571792) 1571792..1572014 + 223 NuclAT_0 - Antitoxin
QLQ05_RS08195 (1571938) 1571938..1572117 - 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
QLQ05_RS08200 (1572263) 1572263..1572712 + 450 WP_003229933.1 phage portal protein -
QLQ05_RS08205 (1572754) 1572754..1572891 + 138 WP_003229934.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 1551114..1662348 111234


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T282346 WP_004398662.1 NZ_CP125762:c1572117-1571938 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

Antitoxin


Download         Length: 223 bp

>AT282346 NZ_CP125762:1571792-1572014 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References