Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2677845..2678170 Replicon chromosome
Accession NZ_CP125660
Organism Bacillus subtilis strain GUCC48

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag QLH41_RS14100 Protein ID WP_004398662.1
Coordinates 2677845..2678024 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2677948..2678170 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLH41_RS14090 (2677071) 2677071..2677208 - 138 WP_003229934.1 hypothetical protein -
QLH41_RS14095 (2677250) 2677250..2677699 - 450 WP_003229933.1 phage portal protein -
QLH41_RS14100 (2677845) 2677845..2678024 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- (2677948) 2677948..2678170 - 223 NuclAT_0 - Antitoxin
- (2677948) 2677948..2678170 - 223 NuclAT_0 - Antitoxin
- (2677948) 2677948..2678170 - 223 NuclAT_0 - Antitoxin
- (2677948) 2677948..2678170 - 223 NuclAT_0 - Antitoxin
QLH41_RS14105 (2678404) 2678404..2678493 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
QLH41_RS14110 (2678747) 2678747..2679190 - 444 WP_003229930.1 phage tail tube protein -
QLH41_RS14115 (2679193) 2679193..2680593 - 1401 WP_003229929.1 phage tail sheath family protein -
QLH41_RS14120 (2680594) 2680594..2680785 - 192 WP_010886574.1 hypothetical protein -
QLH41_RS14125 (2680782) 2680782..2681219 - 438 WP_003229927.1 hypothetical protein -
QLH41_RS14130 (2681232) 2681232..2681735 - 504 WP_003246050.1 HK97 gp10 family phage protein -
QLH41_RS14135 (2681732) 2681732..2682094 - 363 WP_003229925.1 YqbH/XkdH family protein -
QLH41_RS14140 (2682091) 2682091..2682486 - 396 WP_004398566.1 DUF3199 family protein -
QLH41_RS14145 (2682490) 2682490..2682801 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2645095..2698848 53753


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T282266 WP_004398662.1 NZ_CP125660:2677845-2678024 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

Antitoxin


Download         Length: 223 bp

>AT282266 NZ_CP125660:c2678170-2677948 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References