Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2042965..2043290 Replicon chromosome
Accession NZ_CP120681
Organism Bacillus subtilis strain DSM 10

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag P5655_RS11245 Protein ID WP_004398662.1
Coordinates 2042965..2043144 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2043068..2043290 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P5655_RS11235 (2042191) 2042191..2042328 - 138 WP_003229934.1 hypothetical protein -
P5655_RS11240 (2042370) 2042370..2042819 - 450 WP_003229933.1 phage portal protein -
P5655_RS11245 (2042965) 2042965..2043144 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- (2043068) 2043068..2043290 - 223 NuclAT_0 - Antitoxin
- (2043068) 2043068..2043290 - 223 NuclAT_0 - Antitoxin
- (2043068) 2043068..2043290 - 223 NuclAT_0 - Antitoxin
- (2043068) 2043068..2043290 - 223 NuclAT_0 - Antitoxin
P5655_RS11250 (2043524) 2043524..2043613 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
P5655_RS11255 (2043867) 2043867..2044310 - 444 WP_003229930.1 phage tail tube protein -
P5655_RS11260 (2044313) 2044313..2045713 - 1401 WP_003229929.1 phage tail sheath family protein -
P5655_RS11265 (2045714) 2045714..2045905 - 192 WP_010886574.1 hypothetical protein -
P5655_RS11270 (2045902) 2045902..2046339 - 438 WP_003229927.1 hypothetical protein -
P5655_RS11275 (2046352) 2046352..2046855 - 504 WP_003246050.1 HK97 gp10 family phage protein -
P5655_RS11280 (2046852) 2046852..2047214 - 363 WP_003229925.1 YqbH/XkdH family protein -
P5655_RS11285 (2047211) 2047211..2047606 - 396 WP_004398566.1 DUF3199 family protein -
P5655_RS11290 (2047610) 2047610..2047921 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2010216..2063968 53752


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T275365 WP_004398662.1 NZ_CP120681:2042965-2043144 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

Antitoxin


Download         Length: 223 bp

>AT275365 NZ_CP120681:c2043290-2043068 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References