275279

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2534126..2534451 Replicon chromosome
Accession NZ_CP120622
Organism Bacillus subtilis strain DSM 1090

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag P5647_RS13070 Protein ID WP_004398662.1
Coordinates 2534126..2534305 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2534229..2534451 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P5647_RS13060 (2533352) 2533352..2533489 - 138 WP_003229934.1 hypothetical protein -
P5647_RS13065 (2533531) 2533531..2533980 - 450 WP_003229933.1 phage portal protein -
P5647_RS13070 (2534126) 2534126..2534305 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- (2534229) 2534229..2534451 - 223 NuclAT_0 - Antitoxin
- (2534229) 2534229..2534451 - 223 NuclAT_0 - Antitoxin
- (2534229) 2534229..2534451 - 223 NuclAT_0 - Antitoxin
- (2534229) 2534229..2534451 - 223 NuclAT_0 - Antitoxin
P5647_RS13075 (2534685) 2534685..2534774 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
P5647_RS13080 (2535028) 2535028..2535471 - 444 WP_003229930.1 phage tail tube protein -
P5647_RS13085 (2535474) 2535474..2536874 - 1401 WP_003229929.1 phage tail sheath family protein -
P5647_RS13090 (2536875) 2536875..2537066 - 192 WP_010886574.1 hypothetical protein -
P5647_RS13095 (2537063) 2537063..2537500 - 438 WP_003229927.1 hypothetical protein -
P5647_RS13100 (2537513) 2537513..2538016 - 504 WP_003246050.1 HK97 gp10 family phage protein -
P5647_RS13105 (2538013) 2538013..2538375 - 363 WP_003229925.1 YqbH/XkdH family protein -
P5647_RS13110 (2538372) 2538372..2538767 - 396 WP_004398566.1 DUF3199 family protein -
P5647_RS13115 (2538771) 2538771..2539082 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2501376..2555129 53753


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T275279 WP_004398662.1 NZ_CP120622:2534126-2534305 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

Antitoxin


Download         Length: 223 bp

>AT275279 NZ_CP120622:c2534451-2534229 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References