Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2195618..2195943 Replicon chromosome
Accession NZ_CP120598
Organism Bacillus subtilis strain PRO115

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag P5622_RS11550 Protein ID WP_004398662.1
Coordinates 2195764..2195943 (-) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2195618..2195840 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P5622_RS11505 (2190987) 2190987..2191298 + 312 WP_003229923.1 YqbF domain-containing protein -
P5622_RS11510 (2191302) 2191302..2191697 + 396 WP_004398566.1 DUF3199 family protein -
P5622_RS11515 (2191694) 2191694..2192056 + 363 WP_003229925.1 YqbH/XkdH family protein -
P5622_RS11520 (2192053) 2192053..2192556 + 504 WP_003246050.1 HK97 gp10 family phage protein -
P5622_RS11525 (2192569) 2192569..2193006 + 438 WP_003229927.1 hypothetical protein -
P5622_RS11530 (2193003) 2193003..2193194 + 192 WP_010886574.1 hypothetical protein -
P5622_RS11535 (2193195) 2193195..2194595 + 1401 WP_003229929.1 phage tail sheath family protein -
P5622_RS11540 (2194598) 2194598..2195041 + 444 WP_003229930.1 phage tail tube protein -
P5622_RS11545 (2195295) 2195295..2195384 - 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
- (2195618) 2195618..2195840 + 223 NuclAT_0 - Antitoxin
- (2195618) 2195618..2195840 + 223 NuclAT_0 - Antitoxin
- (2195618) 2195618..2195840 + 223 NuclAT_0 - Antitoxin
- (2195618) 2195618..2195840 + 223 NuclAT_0 - Antitoxin
P5622_RS11550 (2195764) 2195764..2195943 - 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
P5622_RS11555 (2196089) 2196089..2196538 + 450 WP_003229933.1 phage portal protein -
P5622_RS11560 (2196580) 2196580..2196717 + 138 WP_003229934.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2174939..2236637 61698


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T275235 WP_004398662.1 NZ_CP120598:c2195943-2195764 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

Antitoxin


Download         Length: 223 bp

>AT275235 NZ_CP120598:2195618-2195840 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References