Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2686043..2686368 Replicon chromosome
Accession NZ_CP115738
Organism Bacillus subtilis strain W7

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag OSK17_RS14155 Protein ID WP_128751232.1
Coordinates 2686043..2686222 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2686146..2686368 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSK17_RS14145 (2685269) 2685269..2685406 - 138 WP_021480099.1 hypothetical protein -
OSK17_RS14150 (2685448) 2685448..2685897 - 450 WP_032722171.1 phage portal protein -
OSK17_RS14155 (2686043) 2686043..2686222 + 180 WP_128751232.1 type I toxin-antitoxin system toxin TxpA Toxin
- (2686146) 2686146..2686368 - 223 NuclAT_0 - Antitoxin
- (2686146) 2686146..2686368 - 223 NuclAT_0 - Antitoxin
- (2686146) 2686146..2686368 - 223 NuclAT_0 - Antitoxin
- (2686146) 2686146..2686368 - 223 NuclAT_0 - Antitoxin
OSK17_RS14160 (2686602) 2686602..2686691 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
OSK17_RS14165 (2686945) 2686945..2687388 - 444 WP_003229930.1 phage tail tube protein -
OSK17_RS14170 (2687391) 2687391..2688791 - 1401 WP_003229929.1 phage tail sheath family protein -
OSK17_RS14175 (2688792) 2688792..2688983 - 192 WP_010886574.1 hypothetical protein -
OSK17_RS14180 (2688980) 2688980..2689417 - 438 WP_003229927.1 hypothetical protein -
OSK17_RS14185 (2689430) 2689430..2689933 - 504 WP_003246050.1 HK97 gp10 family phage protein -
OSK17_RS14190 (2689930) 2689930..2690292 - 363 WP_003229925.1 YqbH/XkdH family protein -
OSK17_RS14195 (2690289) 2690289..2690684 - 396 WP_004398566.1 DUF3199 family protein -
OSK17_RS14200 (2690688) 2690688..2690999 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2653290..2707046 53756


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6755.19 Da        Isoelectric Point: 8.0288

>T267368 WP_128751232.1 NZ_CP115738:2686043-2686222 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLYMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

Antitoxin


Download         Length: 223 bp

>AT267368 NZ_CP115738:c2686368-2686146 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References