Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | rnlAB/RnlA-RnlB |
Location | 1121838..1123275 | Replicon | chromosome |
Accession | NZ_CP106999 | ||
Organism | Escherichia coli strain SY22A4 |
Toxin (Protein)
Gene name | rnlA | Uniprot ID | P52129 |
Locus tag | OFB05_RS05475 | Protein ID | WP_000155570.1 |
Coordinates | 1122202..1123275 (-) | Length | 358 a.a. |
Antitoxin (Protein)
Gene name | rnlB | Uniprot ID | P52130 |
Locus tag | OFB05_RS05470 | Protein ID | WP_000461704.1 |
Coordinates | 1121838..1122209 (-) | Length | 124 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
OFB05_RS05435 (1117039) | 1117039..1117191 | + | 153 | Protein_1061 | arsenate reductase | - |
OFB05_RS05440 (1117578) | 1117578..1118045 | - | 468 | WP_000702495.1 | protein YfjT | - |
OFB05_RS05445 (1118069) | 1118069..1118512 | - | 444 | WP_000824222.1 | lipoprotein YfjS | - |
OFB05_RS05450 (1118512) | 1118512..1118748 | - | 237 | WP_001144029.1 | protein YpjK | - |
OFB05_RS05455 (1118789) | 1118789..1119490 | - | 702 | WP_000189409.1 | WYL domain-containing protein | - |
OFB05_RS05460 (1119707) | 1119707..1120528 | - | 822 | WP_000197391.1 | DUF932 domain-containing protein | - |
OFB05_RS05465 (1120620) | 1120620..1121483 | - | 864 | WP_000787597.1 | GTPase family protein | - |
OFB05_RS05470 (1121838) | 1121838..1122209 | - | 372 | WP_000461704.1 | type II toxin-antitoxin system antitoxin RnlB | Antitoxin |
OFB05_RS05475 (1122202) | 1122202..1123275 | - | 1074 | WP_000155570.1 | type II toxin-antitoxin system toxin mRNA endoribonuclease RnlA | Toxin |
OFB05_RS05480 (1123417) | 1123417..1123680 | + | 264 | WP_000502050.1 | DUF1524 domain-containing protein | - |
OFB05_RS05485 (1124040) | 1124040..1125656 | + | 1617 | WP_000445380.1 | anti-bacteriophage protein AbpA | - |
OFB05_RS05490 (1125653) | 1125653..1127842 | + | 2190 | WP_000136402.1 | DEAD/DEAH box helicase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Genomic island | - | - | 1101759..1133639 | 31880 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 358 a.a. Molecular weight: 40061.13 Da Isoelectric Point: 6.8293
>T260237 WP_000155570.1 NZ_CP106999:c1123275-1122202 [Escherichia coli]
MTIRSYKNLNLVRANIETESRQFIENKNYSIQSIGPMPGSRAGLRVVFTRPGVNLATVDIFYNGDGSTTIQYLTGANRSL
GQELADHLFETINPAEFEQVNMVLQGFVETSVLPVLELSADESHIEFREHSRNAHTVVWKIISTSYQDELTVSLHITTGK
LQIQGRPLSCYRVFTFNLAALLDLQGLEKVLIRQEDGKANIVQQEVARTYLQTVMADAYPHLHVTAEKLLVSGLCVKLAA
PDLPDYCMLLYPELRTIEGVLKSKMSGLGMPVQQPAGFGTYFDKPAAHYILKPQFAATLRPEQINIISTAYTFFNVERHS
LFHMETVVDASRMISDMARLMGKATRAWGIIKDLYIV
MTIRSYKNLNLVRANIETESRQFIENKNYSIQSIGPMPGSRAGLRVVFTRPGVNLATVDIFYNGDGSTTIQYLTGANRSL
GQELADHLFETINPAEFEQVNMVLQGFVETSVLPVLELSADESHIEFREHSRNAHTVVWKIISTSYQDELTVSLHITTGK
LQIQGRPLSCYRVFTFNLAALLDLQGLEKVLIRQEDGKANIVQQEVARTYLQTVMADAYPHLHVTAEKLLVSGLCVKLAA
PDLPDYCMLLYPELRTIEGVLKSKMSGLGMPVQQPAGFGTYFDKPAAHYILKPQFAATLRPEQINIISTAYTFFNVERHS
LFHMETVVDASRMISDMARLMGKATRAWGIIKDLYIV
Download Length: 1074 bp
Antitoxin
Download Length: 124 a.a. Molecular weight: 13664.69 Da Isoelectric Point: 4.2391
>AT260237 WP_000461704.1 NZ_CP106999:c1122209-1121838 [Escherichia coli]
MFEITGINVSGALKAVVMATGFENPLSSVNEIETKLSALLGSETTGEILFDLLCANGPEWNRFVTLEMKYGRIMLDTAKI
IDEQDVPTHILSKLTFTLRNHPEYLEASVLSPDDVRQVLSMDF
MFEITGINVSGALKAVVMATGFENPLSSVNEIETKLSALLGSETTGEILFDLLCANGPEWNRFVTLEMKYGRIMLDTAKI
IDEQDVPTHILSKLTFTLRNHPEYLEASVLSPDDVRQVLSMDF
Download Length: 372 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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