Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2525928..2526253 Replicon chromosome
Accession NZ_CP106673
Organism Bacillus subtilis strain SRCM116268

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag N7985_RS13000 Protein ID WP_128751232.1
Coordinates 2525928..2526107 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2526031..2526253 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7985_RS12990 (2525154) 2525154..2525291 - 138 WP_021480099.1 hypothetical protein -
N7985_RS12995 (2525333) 2525333..2525782 - 450 WP_032722171.1 phage portal protein -
N7985_RS13000 (2525928) 2525928..2526107 + 180 WP_128751232.1 type I toxin-antitoxin system toxin TxpA Toxin
- (2526031) 2526031..2526253 - 223 NuclAT_0 - Antitoxin
- (2526031) 2526031..2526253 - 223 NuclAT_0 - Antitoxin
- (2526031) 2526031..2526253 - 223 NuclAT_0 - Antitoxin
- (2526031) 2526031..2526253 - 223 NuclAT_0 - Antitoxin
N7985_RS13005 (2526487) 2526487..2526576 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
N7985_RS13010 (2526830) 2526830..2527273 - 444 WP_003229930.1 phage tail tube protein -
N7985_RS13015 (2527276) 2527276..2528676 - 1401 WP_003229929.1 phage tail sheath family protein -
N7985_RS13020 (2528677) 2528677..2528868 - 192 WP_010886574.1 hypothetical protein -
N7985_RS13025 (2528865) 2528865..2529302 - 438 WP_003229927.1 hypothetical protein -
N7985_RS13030 (2529315) 2529315..2529818 - 504 WP_003246050.1 HK97 gp10 family phage protein -
N7985_RS13035 (2529815) 2529815..2530177 - 363 WP_003229925.1 YqbH/XkdH family protein -
N7985_RS13040 (2530174) 2530174..2530569 - 396 WP_004398566.1 DUF3199 family protein -
N7985_RS13045 (2530573) 2530573..2530884 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2493175..2546931 53756


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6755.19 Da        Isoelectric Point: 8.0288

>T259624 WP_128751232.1 NZ_CP106673:2525928-2526107 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLYMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

Antitoxin


Download         Length: 223 bp

>AT259624 NZ_CP106673:c2526253-2526031 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References