Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2705013..2705338 Replicon chromosome
Accession NZ_CP104097
Organism Bacillus subtilis strain GL-4

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag N1207_RS14225 Protein ID WP_128751232.1
Coordinates 2705013..2705192 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2705116..2705338 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N1207_RS14215 (2704239) 2704239..2704376 - 138 WP_021480099.1 hypothetical protein -
N1207_RS14220 (2704418) 2704418..2704867 - 450 WP_032722171.1 phage portal protein -
N1207_RS14225 (2705013) 2705013..2705192 + 180 WP_128751232.1 type I toxin-antitoxin system toxin TxpA Toxin
- (2705116) 2705116..2705338 - 223 NuclAT_0 - Antitoxin
- (2705116) 2705116..2705338 - 223 NuclAT_0 - Antitoxin
- (2705116) 2705116..2705338 - 223 NuclAT_0 - Antitoxin
- (2705116) 2705116..2705338 - 223 NuclAT_0 - Antitoxin
N1207_RS14230 (2705572) 2705572..2705661 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
N1207_RS14235 (2705915) 2705915..2706358 - 444 WP_003229930.1 phage tail tube protein -
N1207_RS14240 (2706361) 2706361..2707761 - 1401 WP_003229929.1 phage tail sheath family protein -
N1207_RS14245 (2707762) 2707762..2707953 - 192 WP_010886574.1 hypothetical protein -
N1207_RS14250 (2707950) 2707950..2708387 - 438 WP_003229927.1 hypothetical protein -
N1207_RS14255 (2708400) 2708400..2708903 - 504 WP_003246050.1 HK97 gp10 family phage protein -
N1207_RS14260 (2708900) 2708900..2709262 - 363 WP_003229925.1 YqbH/XkdH family protein -
N1207_RS14265 (2709259) 2709259..2709654 - 396 WP_004398566.1 DUF3199 family protein -
N1207_RS14270 (2709658) 2709658..2709969 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2672260..2726016 53756
inside Prophage - - 2674522..2726016 51494


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6755.19 Da        Isoelectric Point: 8.0288

>T257161 WP_128751232.1 NZ_CP104097:2705013-2705192 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLYMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

Antitoxin


Download         Length: 223 bp

>AT257161 NZ_CP104097:c2705338-2705116 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References