Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2677867..2678192 Replicon chromosome
Accession NZ_CP103066
Organism Bacillus subtilis strain 0137

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag NXS96_RS14115 Protein ID WP_004398662.1
Coordinates 2677867..2678046 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2677970..2678192 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXS96_RS14105 (2677093) 2677093..2677230 - 138 WP_003229934.1 hypothetical protein -
NXS96_RS14110 (2677272) 2677272..2677721 - 450 WP_003229933.1 phage portal protein -
NXS96_RS14115 (2677867) 2677867..2678046 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- (2677970) 2677970..2678192 - 223 NuclAT_0 - Antitoxin
- (2677970) 2677970..2678192 - 223 NuclAT_0 - Antitoxin
- (2677970) 2677970..2678192 - 223 NuclAT_0 - Antitoxin
- (2677970) 2677970..2678192 - 223 NuclAT_0 - Antitoxin
NXS96_RS14120 (2678426) 2678426..2678515 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
NXS96_RS14125 (2678769) 2678769..2679212 - 444 WP_003229930.1 phage tail tube protein -
NXS96_RS14130 (2679215) 2679215..2680615 - 1401 WP_003229929.1 phage tail sheath family protein -
NXS96_RS14135 (2680616) 2680616..2680807 - 192 WP_010886574.1 hypothetical protein -
NXS96_RS14140 (2680804) 2680804..2681241 - 438 WP_003229927.1 hypothetical protein -
NXS96_RS14145 (2681254) 2681254..2681757 - 504 WP_003246050.1 HK97 gp10 family phage protein -
NXS96_RS14150 (2681754) 2681754..2682116 - 363 WP_003229925.1 YqbH/XkdH family protein -
NXS96_RS14155 (2682113) 2682113..2682508 - 396 WP_004398566.1 DUF3199 family protein -
NXS96_RS14160 (2682512) 2682512..2682823 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2645117..2698870 53753


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T254845 WP_004398662.1 NZ_CP103066:2677867-2678046 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

Antitoxin


Download         Length: 223 bp

>AT254845 NZ_CP103066:c2678192-2677970 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References