Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2677834..2678159 Replicon chromosome
Accession NZ_CP102769
Organism Bacillus subtilis strain YZSR384

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag NVS73_RS14100 Protein ID WP_004398662.1
Coordinates 2677834..2678013 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2677937..2678159 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NVS73_RS14090 (2677060) 2677060..2677197 - 138 WP_003229934.1 hypothetical protein -
NVS73_RS14095 (2677239) 2677239..2677688 - 450 WP_003229933.1 phage portal protein -
NVS73_RS14100 (2677834) 2677834..2678013 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- (2677937) 2677937..2678159 - 223 NuclAT_0 - Antitoxin
- (2677937) 2677937..2678159 - 223 NuclAT_0 - Antitoxin
- (2677937) 2677937..2678159 - 223 NuclAT_0 - Antitoxin
- (2677937) 2677937..2678159 - 223 NuclAT_0 - Antitoxin
NVS73_RS14105 (2678393) 2678393..2678482 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
NVS73_RS14110 (2678736) 2678736..2679179 - 444 WP_003229930.1 phage tail tube protein -
NVS73_RS14115 (2679182) 2679182..2680582 - 1401 WP_003229929.1 phage tail sheath family protein -
NVS73_RS14120 (2680583) 2680583..2680774 - 192 WP_010886574.1 hypothetical protein -
NVS73_RS14125 (2680771) 2680771..2681208 - 438 WP_003229927.1 hypothetical protein -
NVS73_RS14130 (2681221) 2681221..2681724 - 504 WP_003246050.1 HK97 gp10 family phage protein -
NVS73_RS14135 (2681721) 2681721..2682083 - 363 WP_003229925.1 YqbH/XkdH family protein -
NVS73_RS14140 (2682080) 2682080..2682475 - 396 WP_004398566.1 DUF3199 family protein -
NVS73_RS14145 (2682479) 2682479..2682790 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2645084..2698837 53753


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T254180 WP_004398662.1 NZ_CP102769:2677834-2678013 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

>T254180 NZ_CP102769:2677834-2678013 [Bacillus subtilis]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin


Download         Length: 223 bp

>AT254180 NZ_CP102769:c2678159-2677937 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References