Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 3188751..3189304 Replicon chromosome
Accession NC_014500
Organism Dickeya dadantii 3937

Toxin (Protein)


Gene name ccdB Uniprot ID E0SJL3
Locus tag DDA3937_RS13965 Protein ID WP_013318624.1
Coordinates 3188751..3189065 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID E0SJL4
Locus tag DDA3937_RS13970 Protein ID WP_013318625.1
Coordinates 3189068..3189304 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Integrative and Conjugative Element - vgrG2 / hcp 3126494..3201103 74609


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11564.48 Da        Isoelectric Point: 7.9859

>T24907 WP_013318624.1 NC_014500:c3189065-3188751 [Dickeya dadantii 3937]
MQFTVYGNTGKSAVYPLLLDVTSDIIGQLNRRIVIPLLPVEKYPAGRRPERFVPVVRLTDGKEYAVMTHELASIPVQALG
TVFCDASQYRNQIKAAIDFLIDGI

Download         Length: 315 bp

>T24907 NC_014500:c3189065-3188751 [Dickeya dadantii 3937]
ATGCAATTCACCGTATACGGTAATACCGGGAAAAGCGCCGTTTATCCGTTGTTGCTCGATGTCACGAGCGATATTATTGG
ACAGTTGAATCGTCGGATAGTGATCCCGTTACTCCCTGTTGAAAAGTATCCGGCAGGCCGCCGACCGGAGCGCTTTGTCC
CCGTCGTCAGGCTGACGGACGGCAAAGAATACGCCGTAATGACGCACGAGCTGGCAAGTATTCCTGTGCAGGCTCTGGGG
ACTGTGTTTTGTGATGCGTCGCAGTACCGTAATCAGATAAAGGCCGCAATAGACTTCCTCATCGACGGCATTTAG

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9017.02 Da        Isoelectric Point: 6.4792

>AT24907 WP_013318625.1 NC_014500:c3189304-3189068 [Dickeya dadantii 3937]
MTAKQRNTQSVTMTVERALLVRAREAGINLSATLSTALDAELRHHEAKKWQEENREAIDALNRFHDEHGCFSDEYRTF

Download         Length: 237 bp

>AT24907 NC_014500:c3189304-3189068 [Dickeya dadantii 3937]
ATGACCGCGAAACAACGCAACACGCAGAGCGTGACCATGACGGTAGAGCGAGCCTTACTGGTCCGGGCGCGTGAGGCGGG
TATTAACCTGAGTGCTACCCTGTCAACCGCACTGGATGCAGAGCTTCGTCACCATGAAGCGAAAAAATGGCAGGAAGAGA
ACAGGGAGGCCATCGACGCATTAAATCGTTTTCATGATGAACACGGCTGTTTCAGTGATGAATACCGGACGTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB E0SJL3

Antitoxin

Source ID Structure
AlphaFold DB E0SJL4

References