244823

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-as-bsrH/-
Location 2516041..2516374 Replicon chromosome
Accession NZ_CP097130
Organism Bacillus subtilis strain S16

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag M2M89_RS12875 Protein ID WP_004398662.1
Coordinates 2516041..2516220 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2516144..2516374 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M2M89_RS12865 (2515267) 2515267..2515404 - 138 WP_021480099.1 hypothetical protein -
M2M89_RS12870 (2515446) 2515446..2515895 - 450 WP_032722171.1 phage portal protein -
M2M89_RS12875 (2516041) 2516041..2516220 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- (2516144) 2516144..2516374 - 231 NuclAT_0 - Antitoxin
- (2516144) 2516144..2516374 - 231 NuclAT_0 - Antitoxin
- (2516144) 2516144..2516374 - 231 NuclAT_0 - Antitoxin
- (2516144) 2516144..2516374 - 231 NuclAT_0 - Antitoxin
M2M89_RS12880 (2516608) 2516608..2516697 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
M2M89_RS12885 (2516951) 2516951..2517394 - 444 WP_003229930.1 phage tail tube protein -
M2M89_RS12890 (2517397) 2517397..2518797 - 1401 WP_003229929.1 phage tail sheath family protein -
M2M89_RS12895 (2518798) 2518798..2518989 - 192 WP_010886574.1 hypothetical protein -
M2M89_RS12900 (2518986) 2518986..2519423 - 438 WP_003229927.1 hypothetical protein -
M2M89_RS12905 (2519436) 2519436..2519939 - 504 WP_003246050.1 HK97 gp10 family phage protein -
M2M89_RS12910 (2519936) 2519936..2520298 - 363 WP_003229925.1 YqbH/XkdH family protein -
M2M89_RS12915 (2520295) 2520295..2520690 - 396 WP_004398566.1 DUF3199 family protein -
M2M89_RS12920 (2520694) 2520694..2521005 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2483287..2537052 53765


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T244823 WP_004398662.1 NZ_CP097130:2516041-2516220 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

Antitoxin


Download         Length: 231 bp

>AT244823 NZ_CP097130:c2516374-2516144 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACATTACCACTTGTTAAT
GTGTGTTACTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCC
TTTAATAGGAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References