238538

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1055323..1056137 Replicon chromosome
Accession NZ_CP093407
Organism Salmonella enterica subsp. enterica serovar Agona strain R19.0144

Toxin (Protein)


Gene name TacT3 Uniprot ID B5F3Y4
Locus tag MOP55_RS05160 Protein ID WP_000971656.1
Coordinates 1055323..1055850 (-) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID M7S6I2
Locus tag MOP55_RS05165 Protein ID WP_000855694.1
Coordinates 1055847..1056137 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MOP55_RS05130 (1051623) 1051623..1052044 + 422 Protein_1009 cytoplasmic protein -
MOP55_RS05135 (1052212) 1052212..1052451 + 240 Protein_1010 hypothetical protein -
MOP55_RS05140 (1052608) 1052608..1053276 + 669 WP_000445914.1 hypothetical protein -
MOP55_RS05145 (1053303) 1053303..1053797 + 495 WP_000424943.1 hypothetical protein -
MOP55_RS05150 (1054042) 1054042..1054698 - 657 WP_000420449.1 protein-serine/threonine phosphatase -
MOP55_RS05155 (1055048) 1055048..1055250 + 203 Protein_1014 IS5/IS1182 family transposase -
MOP55_RS05160 (1055323) 1055323..1055850 - 528 WP_000971656.1 GNAT family N-acetyltransferase Toxin
MOP55_RS05165 (1055847) 1055847..1056137 - 291 WP_000855694.1 DUF1778 domain-containing protein Antitoxin
MOP55_RS05170 (1056730) 1056730..1057056 + 327 WP_000393296.1 hypothetical protein -
MOP55_RS05175 (1057329) 1057329..1057676 - 348 WP_001555786.1 DUF1493 family protein -
MOP55_RS05180 (1057661) 1057661..1058110 - 450 WP_000381619.1 hypothetical protein -
MOP55_RS05185 (1058542) 1058542..1058985 - 444 WP_000715096.1 SPI-1 type III secretion system invasion lipoprotein InvH -
MOP55_RS05190 (1059441) 1059441..1060091 + 651 WP_001747511.1 type III secretion system transcriptional activator InvF -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
flank IS/Tn - - 1055074..1055250 176


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19156.98 Da        Isoelectric Point: 9.6420

>T238538 WP_000971656.1 NZ_CP093407:c1055850-1055323 [Salmonella enterica subsp. enterica serovar Agona]
MMFTDWHEAAIGKTHNRMNFDCGNADLNQFLQRHARQNHEKGTTKTYVALDNSDVTRIHSFYSVSPASLIYAQVPGAISK
GLGRYDVPVFRLDRLAVDKSMQGQGLGAQLLLSAGKRCIQAALQVGGVALLIDAKNKQVCDWYKGFGAVPLNDQPLSLLL
SFKTLYAALSASGRL

Download         Length: 528 bp

>T238538 NZ_LR890384:3969672-3969890 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10664.50 Da        Isoelectric Point: 6.3133

>AT238538 WP_000855694.1 NZ_CP093407:c1056137-1055847 [Salmonella enterica subsp. enterica serovar Agona]
MKTMPQIAIESNERLSLRVSTDAKKLIVRAAAIQQTNLTDFVVSNVLPVAQKIVDAAERVYLTERDTQMIMEILDNPPAP
NEKLLAAAFALPDMKK

Download         Length: 291 bp

>AT238538 NZ_LR890384:3969271-3969645 [Klebsiella pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAACTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3J3UPI2

Antitoxin

Source ID Structure
AlphaFold DB A0A3V8SJE7

References