Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | txpA-ratA/- |
| Location | 2682836..2683161 | Replicon | chromosome |
| Accession | NZ_CP089592 | ||
| Organism | Bacillus subtilis strain Bsi | ||
Toxin (Protein)
| Gene name | txpA | Uniprot ID | P54373 |
| Locus tag | LUV29_RS14105 | Protein ID | WP_004398662.1 |
| Coordinates | 2682836..2683015 (+) | Length | 60 a.a. |
Antitoxin (RNA)
| Gene name | ratA | ||
| Locus tag | - | ||
| Coordinates | 2682939..2683161 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LUV29_RS14095 (2682062) | 2682062..2682199 | - | 138 | WP_003229934.1 | hypothetical protein | - |
| LUV29_RS14100 (2682241) | 2682241..2682690 | - | 450 | WP_003229933.1 | phage portal protein | - |
| LUV29_RS14105 (2682836) | 2682836..2683015 | + | 180 | WP_004398662.1 | type I toxin-antitoxin system toxin TxpA | Toxin |
| - (2682939) | 2682939..2683161 | - | 223 | NuclAT_0 | - | Antitoxin |
| - (2682939) | 2682939..2683161 | - | 223 | NuclAT_0 | - | Antitoxin |
| - (2682939) | 2682939..2683161 | - | 223 | NuclAT_0 | - | Antitoxin |
| - (2682939) | 2682939..2683161 | - | 223 | NuclAT_0 | - | Antitoxin |
| LUV29_RS14110 (2683395) | 2683395..2683484 | + | 90 | WP_075058862.1 | type I toxin-antitoxin system toxin BsrH | - |
| LUV29_RS14115 (2683738) | 2683738..2684181 | - | 444 | WP_003229930.1 | phage tail tube protein | - |
| LUV29_RS14120 (2684184) | 2684184..2685584 | - | 1401 | WP_003229929.1 | phage tail sheath family protein | - |
| LUV29_RS14125 (2685585) | 2685585..2685776 | - | 192 | WP_010886574.1 | hypothetical protein | - |
| LUV29_RS14130 (2685773) | 2685773..2686210 | - | 438 | WP_003229927.1 | hypothetical protein | - |
| LUV29_RS14135 (2686223) | 2686223..2686726 | - | 504 | WP_003246050.1 | HK97 gp10 family phage protein | - |
| LUV29_RS14140 (2686723) | 2686723..2687085 | - | 363 | WP_003229925.1 | YqbH/XkdH family protein | - |
| LUV29_RS14145 (2687082) | 2687082..2687477 | - | 396 | WP_004398566.1 | DUF3199 family protein | - |
| LUV29_RS14150 (2687481) | 2687481..2687792 | - | 312 | WP_003229923.1 | YqbF domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| inside | Prophage | - | - | 2642139..2703839 | 61700 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 60 a.a. Molecular weight: 6739.19 Da Isoelectric Point: 8.0370
>T228408 WP_004398662.1 NZ_CP089592:2682836-2683015 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG
Download Length: 180 bp
>T228408 NZ_CP123914:15377-16324 [Acinetobacter bereziniae]
ATGCCTGATATAAAAAATGTGTTTGCAGATGTCGCTGATGCACTTGGTATTGGTGCAACTTCTATTGTTGAAAAAGATTA
CTATGTTGTCGAGTTATTGAGACTATTACAGTCTCTAGAATTTGAAACGCATGACTTGGTTTTTGCTGGTGGAACTTCTT
TAGCTAAAGCAAATATTCAGTTAAATCGGATGTCTGAAGATGTGGACATTAAAATAGTTCCAAAACCAAATATTGCATTA
AGTCGCTCTAAAGCTAAAGTTGTACGTAAACAATTGCTTCATCAAGTACAAGACAAAATCTCTCAATCTGATTTCTTTAC
AATTGAAGAGGAACCAGTTGTCTGGGATGAATATCGTTATATGGAATTATTAATTCGATATCCTCAGCATTTCAACCAAG
CTCCCTGTTTACGACCATTCATTAAATTGGAATTAGTTGAAACAGACTTACTTGAGCCTTTTGAATCTAGAAGTATCACC
TCGTTTGTGTATGACTTGGCTAAGAAAGGGAAGCCAGTCGATGCTTTTCCCTCCGTCACAATTGTCAGTACCAGTATCGA
GAAGCTGATAGCAATTTTAAGGCGTACAGCGGCCTTTGCTAGAAATGCTGAAAGAGCTGATGATGAATCATTAGTTCGAC
ATGTGTATGACTACTTTAAAATTACCTATGGTAAACCACAAGATTTTGTTTATTTAGGGCACTTAGCTACTAAAGTTATA
AAAACTGATATTGAGCGTTATGGTCGTCAGCATACTCTTATGGTTGAAGACCCGATTGCTGAATTGTTATTTGGTTTAAA
TGAATTAAGTCGTAATCCACTCTATAAAGCCAGGTTTAATAATTTTGTTGTTCCTATGGTGTTCGGGGACAAACAAATAT
CATGGCAGCAAGCCTATTCACATTTTCAGGACTCAGTTCAACAGATCTTCGCTAACTTAAAGTTGTAA
ATGCCTGATATAAAAAATGTGTTTGCAGATGTCGCTGATGCACTTGGTATTGGTGCAACTTCTATTGTTGAAAAAGATTA
CTATGTTGTCGAGTTATTGAGACTATTACAGTCTCTAGAATTTGAAACGCATGACTTGGTTTTTGCTGGTGGAACTTCTT
TAGCTAAAGCAAATATTCAGTTAAATCGGATGTCTGAAGATGTGGACATTAAAATAGTTCCAAAACCAAATATTGCATTA
AGTCGCTCTAAAGCTAAAGTTGTACGTAAACAATTGCTTCATCAAGTACAAGACAAAATCTCTCAATCTGATTTCTTTAC
AATTGAAGAGGAACCAGTTGTCTGGGATGAATATCGTTATATGGAATTATTAATTCGATATCCTCAGCATTTCAACCAAG
CTCCCTGTTTACGACCATTCATTAAATTGGAATTAGTTGAAACAGACTTACTTGAGCCTTTTGAATCTAGAAGTATCACC
TCGTTTGTGTATGACTTGGCTAAGAAAGGGAAGCCAGTCGATGCTTTTCCCTCCGTCACAATTGTCAGTACCAGTATCGA
GAAGCTGATAGCAATTTTAAGGCGTACAGCGGCCTTTGCTAGAAATGCTGAAAGAGCTGATGATGAATCATTAGTTCGAC
ATGTGTATGACTACTTTAAAATTACCTATGGTAAACCACAAGATTTTGTTTATTTAGGGCACTTAGCTACTAAAGTTATA
AAAACTGATATTGAGCGTTATGGTCGTCAGCATACTCTTATGGTTGAAGACCCGATTGCTGAATTGTTATTTGGTTTAAA
TGAATTAAGTCGTAATCCACTCTATAAAGCCAGGTTTAATAATTTTGTTGTTCCTATGGTGTTCGGGGACAAACAAATAT
CATGGCAGCAAGCCTATTCACATTTTCAGGACTCAGTTCAACAGATCTTCGCTAACTTAAAGTTGTAA
Antitoxin
Download Length: 223 bp
>AT228408 NZ_CP089592:c2683161-2682939 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
