Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1340532..1341346 Replicon chromosome
Accession NZ_CP085824
Organism Salmonella enterica subsp. enterica serovar Enteritidis strain Ivysaur

Toxin (Protein)


Gene name TacT3 Uniprot ID Q57KM2
Locus tag LJF36_RS06405 Protein ID WP_000971655.1
Coordinates 1340532..1341059 (-) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID M7S6I2
Locus tag LJF36_RS06410 Protein ID WP_000855694.1
Coordinates 1341056..1341346 (-) Length 97 a.a.

Genomic Context

LJF36_RS06380LJF36_RS06385LJF36_RS06390LJF36_RS06400LJF36_RS06425LJF36_RS06430LJF36_RS06395LJF36_RS06405LJF36_RS06410LJF36_RS06415LJF36_RS06420
Location: 1336821..1337219 (399 bp)
Type: Others
Protein ID: Protein_1228
Location: 1337805..1338473 (669 bp)
Type: Others
Protein ID: WP_000445914.1
Location: 1338500..1338994 (495 bp)
Type: Others
Protein ID: WP_000424949.1
Location: 1340254..1340459 (206 bp)
Type: Others
Protein ID: Protein_1232
Location: 1343108..1343758 (651 bp)
Type: Others
Protein ID: WP_001674874.1
Location: 1343755..1345443 (1689 bp)
Type: Others
Protein ID: WP_000848113.1
Location: 1339239..1339895 (657 bp)
Type: Others
Protein ID: WP_000420452.1
Location: 1340532..1341059 (528 bp)
Type: Toxin
Protein ID: WP_000971655.1
Location: 1341056..1341346 (291 bp)
Type: Antitoxin
Protein ID: WP_000855694.1
Location: 1341616..1341805 (190 bp)
Type: Others
Protein ID: Protein_1235
Location: 1342209..1342652 (444 bp)
Type: Others
Protein ID: WP_000715097.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LJF36_RS06380 (1336821)1336821..1337219+399Protein_1228cytoplasmic protein-
LJF36_RS06385 (1337805)1337805..1338473+669WP_000445914.1hypothetical protein-
LJF36_RS06390 (1338500)1338500..1338994+495WP_000424949.1hypothetical protein-
LJF36_RS06395 (1339239)1339239..1339895-657WP_000420452.1protein-serine/threonine phosphatase-
LJF36_RS06400 (1340254)1340254..1340459+206Protein_1232IS5/IS1182 family transposase-
LJF36_RS06405 (1340532)1340532..1341059-528WP_000971655.1GNAT family N-acetyltransferaseToxin
LJF36_RS06410 (1341056)1341056..1341346-291WP_000855694.1DUF1778 domain-containing proteinAntitoxin
LJF36_RS06415 (1341616)1341616..1341805-190Protein_1235IS3 family transposase-
LJF36_RS06420 (1342209)1342209..1342652-444WP_000715097.1SPI-1 type III secretion system invasion lipoprotein InvH-
LJF36_RS06425 (1343108)1343108..1343758+651WP_001674874.1type III secretion system transcriptional activator InvF-
LJF36_RS06430 (1343755)1343755..1345443+1689WP_000848113.1type III secretion system outer membrane ring protein InvG-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
flankIS/Tn--1340283..1340459176


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19069.91 Da        Isoelectric Point: 9.6420

>T222088 WP_000971655.1 NZ_CP085824:c1341059-1340532 [Salmonella enterica subsp. enterica serovar Enteritidis]
MMFTDWHEAAIGKTHNRMNFDCGDADLNQFLQRHARQNHEKGTTKTYVALDNSDVTRIHGFYSVSPASLIYAQVPGAISK
GLGRYDVPVFRLGRLAVDKSMQGQGLGAQLLLSAGKRCIQAALQVGGVALLIDAKNKQVCDWYKGFGAVPLNDQPLSLLL
SFKTLYAALSASGRL

Download         Length: 528 bp

>T222088 NZ_CP117678:c2734520-2733993 [Escherichia albertii]
ATGGATGATCTGACGATAGAGATTCTGACCGATGATGCAGATTATGATCTACAGCGATTAGACTGCGGCGAGGAAGCGTT
AAATCTCTTTCTGACGACACATCTGGTTCGTCAACATCGCAATAAAATTTTGCGAGCGTATATCCTTTGTAGCAACACTC
CAGAACGTCAGGTCCTGGGATATTACACATTATCCGGCAGTTGTTTTGAACGAGCCGCACTGCCCTCGAAATCGAAACAG
AAAAAAATTCCCTACAAAAATATTCCCAGCGTCACTCTTGGGCGTCTGGCAATTGATCGTTCATTACAGGGGCAGGGATG
GGGAGCAACACTGGTTGCTCATGCCATGAAAGTCGTCTGCTCAGCCTCATTAGCGGTAGGTATTCACGGTCTTTTTGTCG
AGGCTCTGAATGAAAAAGCCCATACGTTTTATCAGTCGCTGGGCTTTATCCCGTTGGTTGGAGAAAACGAAAATGCGTTA
TTTTTCCCAACCAAATCCATTGAACTGCTTTTTACACAGAGCGATTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10664.50 Da        Isoelectric Point: 6.3133

>AT222088 WP_000855694.1 NZ_CP085824:c1341346-1341056 [Salmonella enterica subsp. enterica serovar Enteritidis]
MKTMPQIAIESNERLSLRVSTDAKKLIVRAAAIQQTNLTDFVVSNVLPVAQKIVDAAERVYLTERDTQMIMEILDNPPAP
NEKLLAAAFALPDMKK

Download         Length: 291 bp

>AT222088 NZ_CP117678:c2734793-2734527 [Escherichia albertii]
ATGTCTGCTGTTAAAAAGCAGCGTATCGATCTGCGTTTAACTGACGATGACAAAAGTATGATTGAGGAAGCGGCAGCGAT
ATCTAATCAATCCGTCAGCCAATTTATGTTGAACAGCGCTTCGCAGCGAGCTGCGGAAGTGATTGAACAGCATCGGCGGA
TGATTCTCAATGAGGAATCCTGGACGCGGGTGATGGATGCGCTGAGTAATCCACCGTCACCAGGTGAAAAGTTAAAACGT
GCGGCAAAACGTCTTCAGGGAATGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
PDB6G96
PDB7AK9

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A3V8SJE7

References