21004

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Txe-RelB
Location 2676792..2677198 Replicon chromosome
Accession NC_005126
Organism Photorhabdus luminescens subsp. laumondii TTO1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PLU_RS25325 Protein ID WP_071824109.1
Coordinates 2676792..2676884 (-) Length 31 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag PLU_RS11380 Protein ID WP_011146529.1
Coordinates 2676944..2677198 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PLU_RS11355 (plu2275) 2673062..2674381 + 1320 WP_011146524.1 xylose isomerase -
PLU_RS11360 (plu2276) 2674801..2675373 + 573 WP_011146525.1 hypothetical protein -
PLU_RS11365 (plu2277) 2675665..2676039 + 375 WP_041380079.1 VOC family protein -
PLU_RS11370 (plu2278) 2676127..2676366 + 240 WP_011146527.1 type II toxin-antitoxin system CcdA family antitoxin -
PLU_RS11375 (plu2279) 2676368..2676673 + 306 WP_011146528.1 CcdB family protein -
PLU_RS25325 2676792..2676884 - 93 WP_071824109.1 type II toxin-antitoxin system YoeB family toxin Toxin
PLU_RS11380 (plu2280) 2676944..2677198 - 255 WP_011146529.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PLU_RS24565 (plu2281) 2677254..2677712 - 459 WP_011146530.1 Exc2 family lipoprotein -
PLU_RS11390 (plu2282) 2677694..2678662 - 969 WP_011145223.1 IS30-like element ISPlu1 family transposase -
PLU_RS11395 (plu2283) 2678805..2679005 - 201 WP_011146531.1 DUF1778 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
flank IS/Tn - - 2677694..2678662 968


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-28)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 31 a.a.        Molecular weight: 3720.27 Da        Isoelectric Point: 9.7449

>T21004 WP_071824109.1 NC_005126:c2676884-2676792 [Photorhabdus laumondii subsp. laumondii TTO1]
MSGYWSRRINREHRLVYKVTDDAIIIVQHY

Download         Length: 93 bp

>T21004 NC_005126:c2676884-2676792 [Photorhabdus laumondii subsp. laumondii TTO1]
TTGTCGGGTTATTGGTCTAGACGTATTAATCGAGAGCATCGTCTGGTTTACAAGGTAACAGATGATGCAATCATTATCGT
GCAGCACTATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9422.72 Da        Isoelectric Point: 6.4794

>AT21004 WP_011146529.1 NC_005126:c2677198-2676944 [Photorhabdus laumondii subsp. laumondii TTO1]
MDTINYSAFRTHFASPLDKVNDNHKPILITHQNGKPAIALRLEDFQAYEETAYLMASPKNAAHLNQAIAEVEAGRMIEKG
LLKE

Download         Length: 255 bp

>AT21004 NC_005126:c2677198-2676944 [Photorhabdus laumondii subsp. laumondii TTO1]
ATGGACACAATAAACTATTCAGCATTTAGAACTCACTTCGCCAGCCCCTTAGATAAAGTGAACGACAATCACAAGCCAAT
TCTGATTACTCATCAGAATGGCAAGCCAGCGATCGCCCTACGTTTGGAAGATTTTCAAGCCTACGAAGAAACAGCCTATT
TAATGGCTAGCCCGAAAAACGCGGCACATTTAAATCAGGCAATTGCTGAAGTGGAAGCAGGGAGAATGATTGAAAAAGGG
CTATTGAAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References