Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Txe-RelB
Location 2676791..2677197 Replicon chromosome
Accession NZ_CP015281
Organism Photorhabdus laumondii subsp. laumondii strain DSPV002N

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag A4R40_RS11785 Protein ID WP_071824109.1
Coordinates 2676791..2676883 (-) Length 31 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag A4R40_RS11790 Protein ID WP_011146529.1
Coordinates 2676943..2677197 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A4R40_RS11760 2673061..2674380 + 1320 WP_011146524.1 xylose isomerase -
A4R40_RS11765 2674800..2675372 + 573 WP_011146525.1 hypothetical protein -
A4R40_RS11770 2675664..2676038 + 375 WP_041380079.1 VOC family protein -
A4R40_RS11775 2676126..2676365 + 240 WP_011146527.1 type II toxin-antitoxin system CcdA family antitoxin -
A4R40_RS11780 2676367..2676672 + 306 WP_011146528.1 CcdB family protein -
A4R40_RS11785 2676791..2676883 - 93 WP_071824109.1 type II toxin-antitoxin system YoeB family toxin Toxin
A4R40_RS11790 2676943..2677197 - 255 WP_011146529.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
A4R40_RS11795 2677253..2677711 - 459 WP_109791560.1 Exc2 family lipoprotein -
A4R40_RS11800 2677693..2678661 - 969 WP_011145223.1 IS30-like element ISPlu1 family transposase -
A4R40_RS11805 2678804..2679004 - 201 WP_011146531.1 DUF1778 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
flank IS/Tn - - 2677693..2678661 968


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-28)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 31 a.a.        Molecular weight: 3720.27 Da        Isoelectric Point: 9.7449

>T62845 WP_071824109.1 NZ_CP015281:c2676883-2676791 [Photorhabdus laumondii subsp. laumondii]
MSGYWSRRINREHRLVYKVTDDAIIIVQHY

Download         Length: 93 bp

>T62845 NZ_CP015281:c2676883-2676791 [Photorhabdus laumondii subsp. laumondii]
TTGTCGGGTTATTGGTCTAGACGTATTAATCGAGAGCATCGTCTGGTTTACAAGGTAACAGATGATGCAATCATTATCGT
GCAGCACTATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9422.72 Da        Isoelectric Point: 6.4794

>AT62845 WP_011146529.1 NZ_CP015281:c2677197-2676943 [Photorhabdus laumondii subsp. laumondii]
MDTINYSAFRTHFASPLDKVNDNHKPILITHQNGKPAIALRLEDFQAYEETAYLMASPKNAAHLNQAIAEVEAGRMIEKG
LLKE

Download         Length: 255 bp

>AT62845 NZ_CP015281:c2677197-2676943 [Photorhabdus laumondii subsp. laumondii]
ATGGACACAATAAACTATTCAGCATTTAGAACTCACTTCGCCAGCCCCTTAGATAAAGTGAACGACAATCACAAGCCAAT
TCTGATTACTCATCAGAATGGCAAGCCAGCGATCGCCCTACGTTTGGAAGATTTTCAAGCCTACGAAGAAACAGCCTATT
TAATGGCTAGCCCGAAAAACGCGGCACATTTAAATCAGGCAATTGCTGAAGTGGAAGCAGGGAGAATGATTGAAAAAGGG
CTATTGAAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References