Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-SprF3/- |
Location | 2586111..2586410 | Replicon | chromosome |
Accession | NZ_CP079715 | ||
Organism | Staphylococcus aureus strain V8 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | Q2FWU9 |
Locus tag | KX797_RS12980 | Protein ID | WP_011447039.1 |
Coordinates | 2586234..2586410 (-) | Length | 59 a.a. |
Antitoxin (RNA)
Gene name | SprF3 | ||
Locus tag | - | ||
Coordinates | 2586111..2586166 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KX797_RS12940 | 2581442..2581702 | + | 261 | WP_001791826.1 | hypothetical protein | - |
KX797_RS12945 | 2581755..2582105 | - | 351 | WP_000702263.1 | complement inhibitor SCIN-A | - |
KX797_RS12950 | 2582790..2583239 | + | 450 | WP_000727649.1 | chemotaxis-inhibiting protein CHIPS | - |
KX797_RS12955 | 2583334..2583669 | - | 336 | Protein_2521 | SH3 domain-containing protein | - |
KX797_RS12960 | 2584319..2584810 | - | 492 | WP_000919350.1 | staphylokinase | - |
KX797_RS12965 | 2585001..2585756 | - | 756 | WP_000861038.1 | CHAP domain-containing protein | - |
KX797_RS12970 | 2585768..2586022 | - | 255 | WP_000611512.1 | phage holin | - |
KX797_RS12975 | 2586074..2586181 | + | 108 | WP_001791821.1 | hypothetical protein | - |
- | 2586103..2586242 | + | 140 | NuclAT_0 | - | - |
- | 2586103..2586242 | + | 140 | NuclAT_0 | - | - |
- | 2586103..2586242 | + | 140 | NuclAT_0 | - | - |
- | 2586103..2586242 | + | 140 | NuclAT_0 | - | - |
- | 2586111..2586166 | + | 56 | - | - | Antitoxin |
KX797_RS12980 | 2586234..2586410 | - | 177 | WP_011447039.1 | type I toxin-antitoxin system toxin PepG1 | Toxin |
KX797_RS12985 | 2586519..2587292 | - | 774 | WP_000750406.1 | staphylococcal enterotoxin type A | - |
KX797_RS12990 | 2587713..2588087 | - | 375 | WP_000340977.1 | hypothetical protein | - |
KX797_RS12995 | 2588143..2588430 | - | 288 | WP_001040259.1 | hypothetical protein | - |
KX797_RS13000 | 2588477..2588629 | - | 153 | WP_001153681.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | scn / chp / sak / sea / hlb / groEL | 2581755..2638705 | 56950 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 59 a.a. Molecular weight: 6849.45 Da Isoelectric Point: 10.6777
>T209767 WP_011447039.1 NZ_CP079715:c2586410-2586234 [Staphylococcus aureus]
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK
Download Length: 177 bp
>T209767 NZ_CP104302:c2372367-2371963 [Mycolicibacterium brumae]
ATGATCTACCTCGACACCTCCGCTCTGGTGAAACTGCTCGTCACCGAGGACGAGACGCCCGCCTTGAGAAGGTGGCTTTC
GGAACAGACCTCAGGCGGGGTGTTCGCAGCCACCAGCACGCTGGGTCGGATCGAGCTGATGAGGGCCGCCGCTCGATATT
CCGAACCGGGGCTCGCTGACCGCGCGCGGTTCCTGCTCGACGGGATGGACCTGCTGCCGCTCACTGAATCTGTGCTGACC
CTCGCGGAAACAATCGGCCCGCCTTCACTGCGATCCCTCGACGCAATCCACCTGGCGGCGGCCGCCCACGTCCGCGATGA
ACTGACGGCGTTCGTGACGTATGACCGGCGACTGCTCGACGGCTGCTGTGACGTGGGGCTTGCCGTCGTGTCGCCCGGCG
CGTAG
ATGATCTACCTCGACACCTCCGCTCTGGTGAAACTGCTCGTCACCGAGGACGAGACGCCCGCCTTGAGAAGGTGGCTTTC
GGAACAGACCTCAGGCGGGGTGTTCGCAGCCACCAGCACGCTGGGTCGGATCGAGCTGATGAGGGCCGCCGCTCGATATT
CCGAACCGGGGCTCGCTGACCGCGCGCGGTTCCTGCTCGACGGGATGGACCTGCTGCCGCTCACTGAATCTGTGCTGACC
CTCGCGGAAACAATCGGCCCGCCTTCACTGCGATCCCTCGACGCAATCCACCTGGCGGCGGCCGCCCACGTCCGCGATGA
ACTGACGGCGTTCGTGACGTATGACCGGCGACTGCTCGACGGCTGCTGTGACGTGGGGCTTGCCGTCGTGTCGCCCGGCG
CGTAG
Antitoxin
Download Length: 56 bp
>AT209767 NZ_CP079715:2586111-2586166 [Staphylococcus aureus]
AAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG
AAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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