203028

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 988546..989360 Replicon chromosome
Accession NZ_CP075120
Organism Salmonella enterica subsp. enterica serovar Enteritidis strain CFSAN051882

Toxin (Protein)


Gene name TacT3 Uniprot ID Q57KM2
Locus tag BCB01_RS04720 Protein ID WP_000971655.1
Coordinates 988546..989073 (-) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID M7S6I2
Locus tag BCB01_RS04725 Protein ID WP_000855694.1
Coordinates 989070..989360 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BCB01_RS04695 (984835) 984835..985233 + 399 Protein_918 cytoplasmic protein -
BCB01_RS04700 (985819) 985819..986487 + 669 WP_000445914.1 hypothetical protein -
BCB01_RS04705 (986514) 986514..987008 + 495 WP_000424949.1 hypothetical protein -
BCB01_RS04710 (987253) 987253..987909 - 657 WP_000420452.1 protein-serine/threonine phosphatase -
BCB01_RS04715 (988268) 988268..988473 + 206 Protein_922 IS5/IS1182 family transposase -
BCB01_RS04720 (988546) 988546..989073 - 528 WP_000971655.1 GNAT family N-acetyltransferase Toxin
BCB01_RS04725 (989070) 989070..989360 - 291 WP_000855694.1 DUF1778 domain-containing protein Antitoxin
BCB01_RS04730 (989630) 989630..989819 - 190 Protein_925 IS3 family transposase -
BCB01_RS04735 (990223) 990223..990666 - 444 WP_000715096.1 SPI-1 type III secretion system invasion lipoprotein InvH -
BCB01_RS04740 (991122) 991122..991772 + 651 WP_001674874.1 type III secretion system transcriptional activator InvF -
BCB01_RS04745 (991769) 991769..993457 + 1689 WP_000848113.1 type III secretion system outer membrane ring protein InvG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
flank IS/Tn - - 988297..988473 176


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19069.91 Da        Isoelectric Point: 9.6420

>T203028 WP_000971655.1 NZ_CP075120:c989073-988546 [Salmonella enterica subsp. enterica serovar Enteritidis]
MMFTDWHEAAIGKTHNRMNFDCGDADLNQFLQRHARQNHEKGTTKTYVALDNSDVTRIHGFYSVSPASLIYAQVPGAISK
GLGRYDVPVFRLGRLAVDKSMQGQGLGAQLLLSAGKRCIQAALQVGGVALLIDAKNKQVCDWYKGFGAVPLNDQPLSLLL
SFKTLYAALSASGRL

Download         Length: 528 bp

>T203028 NZ_CP099837:1874976-1875380 [Nocardiopsis exhalans]
GTGGACGACGTCTTCTACCTGGACTCGGCGATGGTCATCGAAATCACCACCATGGCTCTGGCCCAGGAAGGCCAGGGCCC
TGCCATGGTTCGCGAAACCGGGCTGCTGGAGAGTGCGGTCCACCGCCCGATGGGGTCTTCGTTCGGGGACGAGCACTACC
CGGACATCTTTGAGAAGGCCGCCGCGTTGATGCACTCCCTGGCCAGAAACCATGTGTTCTTCGACGGCAACAAGCGAGCC
GCGTGGAACTCCGCGGCGACTTTCCTCGAAGTGAACGGGTGGTCCCTGGCGGAACCTGTCGATGTGGATCGCGCCGAGCA
TTTCGTCCTCTATGTCGCCGAGGGAAAACTCGGCGACATCGAGGACATCGCGGCTGCCCTGCGCGCCTTCCACGTGCTGA
ACTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10664.50 Da        Isoelectric Point: 6.3133

>AT203028 WP_000855694.1 NZ_CP075120:c989360-989070 [Salmonella enterica subsp. enterica serovar Enteritidis]
MKTMPQIAIESNERLSLRVSTDAKKLIVRAAAIQQTNLTDFVVSNVLPVAQKIVDAAERVYLTERDTQMIMEILDNPPAP
NEKLLAAAFALPDMKK

Download         Length: 291 bp

>AT203028 NZ_CP099837:1874772-1874975 [Nocardiopsis exhalans]
ATGTCCGCGCTCGGTATCGAGTTCACGGAGGCGGAGTCGGAACAGATCCGGCAGACAGCTGCCGCTGAGCAGCGGTCACC
GCAGGAGCTGGTCCAGGAGATGCGGGAGAGCGTGCTCGCCGACGTCCGTCGCCGCCGCTTCGAGGCTGCGGCAAAGCGCG
TCACCACCCTCTCCGCCGAGCTCAACGAAAGGCTCGCCAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 6G96
PDB 7AK9

Antitoxin

Source ID Structure
AlphaFold DB A0A3V8SJE7

References