Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1792960..1793774 Replicon chromosome
Accession NZ_CP064385
Organism Salmonella enterica subsp. enterica strain PartC-Senterica-RM8376

Toxin (Protein)


Gene name TacT3 Uniprot ID Q57KM2
Locus tag IUJ38_RS08925 Protein ID WP_000971655.1
Coordinates 1793247..1793774 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID E8XL32
Locus tag IUJ38_RS08920 Protein ID WP_000855692.1
Coordinates 1792960..1793250 (+) Length 97 a.a.

Genomic Context

IUJ38_RS08895IUJ38_RS08900IUJ38_RS08905IUJ38_RS08915IUJ38_RS08920IUJ38_RS08925IUJ38_RS08935IUJ38_RS08945IUJ38_RS08890IUJ38_RS08910IUJ38_RS08930IUJ38_RS08940
Location: 1790017..1790460 (444 bp)
Type: Others
Protein ID: WP_000715092.1
Location: 1790891..1791340 (450 bp)
Type: Others
Protein ID: WP_000381610.1
Location: 1791325..1791672 (348 bp)
Type: Others
Protein ID: WP_001669174.1
Location: 1792512..1792690 (179 bp)
Type: Others
Protein ID: Protein_1747
Location: 1792960..1793250 (291 bp)
Type: Antitoxin
Protein ID: WP_000855692.1
Location: 1793247..1793774 (528 bp)
Type: Toxin
Protein ID: WP_000971655.1
Location: 1794399..1795055 (657 bp)
Type: Others
Protein ID: WP_000420452.1
Location: 1795907..1798474 (2568 bp)
Type: Others
Protein ID: WP_001005807.1
Location: 1788910..1789560 (651 bp)
Type: Others
Protein ID: WP_001674874.1
Location: 1791945..1792271 (327 bp)
Type: Others
Protein ID: WP_000393302.1
Location: 1793847..1794052 (206 bp)
Type: Others
Protein ID: Protein_1750
Location: 1795227..1795748 (522 bp)
Type: Others
Protein ID: WP_000858988.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
IUJ38_RS08890 (1788910)1788910..1789560-651WP_001674874.1type III secretion system transcriptional activator InvF-
IUJ38_RS08895 (1790017)1790017..1790460+444WP_000715092.1SPI-1 type III secretion system invasion lipoprotein InvH-
IUJ38_RS08900 (1790891)1790891..1791340+450WP_000381610.1membrane protein-
IUJ38_RS08905 (1791325)1791325..1791672+348WP_001669174.1DUF1493 family protein-
IUJ38_RS08910 (1791945)1791945..1792271-327WP_000393302.1hypothetical protein-
IUJ38_RS08915 (1792512)1792512..1792690+179Protein_1747IS3 family transposase-
IUJ38_RS08920 (1792960)1792960..1793250+291WP_000855692.1DUF1778 domain-containing proteinAntitoxin
IUJ38_RS08925 (1793247)1793247..1793774+528WP_000971655.1GNAT family N-acetyltransferaseToxin
IUJ38_RS08930 (1793847)1793847..1794052-206Protein_1750IS5/IS1182 family transposase-
IUJ38_RS08935 (1794399)1794399..1795055+657WP_000420452.1protein-serine/threonine phosphatase-
IUJ38_RS08940 (1795227)1795227..1795748-522WP_000858988.1hypothetical protein-
IUJ38_RS08945 (1795907)1795907..1798474+2568WP_001005807.1DNA mismatch repair protein MutS-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
flankIS/Tn--1793847..1794023176


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19069.91 Da        Isoelectric Point: 9.6420

>T181071 WP_000971655.1 NZ_CP064385:1793247-1793774 [Salmonella enterica subsp. enterica]
MMFTDWHEAAIGKTHNRMNFDCGDADLNQFLQRHARQNHEKGTTKTYVALDNSDVTRIHGFYSVSPASLIYAQVPGAISK
GLGRYDVPVFRLGRLAVDKSMQGQGLGAQLLLSAGKRCIQAALQVGGVALLIDAKNKQVCDWYKGFGAVPLNDQPLSLLL
SFKTLYAALSASGRL

Download         Length: 528 bp

>T181071 NZ_CP085802:c523177-522650 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGATGTTTACAGACTGGCATGAGGCCGCGATAGGGAAAACCCACAATCGAATGAATTTTGATTGTGGGGATGCCGATCT
GAACCAATTCCTGCAACGCCATGCACGACAAAATCATGAGAAAGGGACAACGAAAACCTATGTTGCGCTTGATAATTCGG
ATGTTACACGTATCCACGGCTTTTACTCAGTCAGTCCTGCATCACTGATATATGCACAGGTTCCCGGCGCAATCAGCAAA
GGATTAGGGAGATACGATGTGCCAGTGTTTCGTCTGGGTCGTTTAGCCGTAGACAAATCTATGCAGGGGCAAGGGCTGGG
AGCACAACTTTTGTTATCTGCCGGAAAGCGTTGCATACAGGCGGCTTTGCAGGTCGGTGGCGTAGCCCTACTTATTGATG
CCAAAAATAAACAGGTCTGCGACTGGTACAAAGGATTTGGCGCAGTACCATTAAACGATCAACCCCTTTCCTTGTTGCTG
TCGTTTAAAACGCTTTATGCTGCTTTATCTGCATCTGGTAGGTTATGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10678.57 Da        Isoelectric Point: 8.5779

>AT181071 WP_000855692.1 NZ_CP064385:1792960-1793250 [Salmonella enterica subsp. enterica]
MKTMPQIAIESNERLSLRVSTDAKKLIVRAAAIQQTNLTDFVVSNILPVAQKIVDAAERVYLTERDTKMIMEILDNPPAP
NEKLLAAAFALPDMKK

Download         Length: 291 bp

>AT181071 NZ_CP085802:c523464-523174 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGAAAACCATGCCTCAGATAGCTATAGAATCTAACGAAAGGCTGTCGTTGCGTGTATCGACGGATGCCAAAAAGTTGAT
AGTCCGCGCTGCGGCAATCCAGCAAACCAACCTGACGGATTTTGTGGTCAGTAACGTACTACCTGTCGCACAGAAGATTG
TTGATGCCGCCGAACGGGTATATCTGACGGAGCGCGATACTCAAATGATCATGGAAATTTTAGATAACCCGCCAGCGCCG
AATGAAAAGCTTCTTGCCGCTGCTTTCGCCCTGCCGGACATGAAGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
PDB6G96
PDB7AK9

Antitoxin

Loading, please wait
Source
ID
Structure
PDB7AK9
AlphaFold DBA0A625WHV3

References