Detailed information of TA system TA180055

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 3007546..3007871
• Replicon: chromosome
• Accession: NZ_CP064094
• Organism: Bacillus subtilis strain N1108-5at

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: P54373
• Locus tag: IRJ26_RS15785
• Protein ID: WP_004398662.1
• Coordinates: 3007692..3007871 (-)
• Length: 60 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	3007546..3007768 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IRJ26_RS15740 (3002915)	3002915..3003226	+	312	WP_003229923.1	YqbF domain-containing protein	-
IRJ26_RS15745 (3003230)	3003230..3003625	+	396	WP_004398566.1	DUF3199 family protein	-
IRJ26_RS15750 (3003622)	3003622..3003984	+	363	WP_003229925.1	YqbH/XkdH family protein	-
IRJ26_RS15755 (3003981)	3003981..3004484	+	504	WP_003246050.1	HK97 gp10 family phage protein	-
IRJ26_RS15760 (3004497)	3004497..3004934	+	438	WP_003229927.1	hypothetical protein	-
IRJ26_RS15765 (3004931)	3004931..3005122	+	192	WP_010886574.1	hypothetical protein	-
IRJ26_RS15770 (3005123)	3005123..3006523	+	1401	WP_003229929.1	phage tail sheath family protein	-
IRJ26_RS15775 (3006526)	3006526..3006969	+	444	WP_003229930.1	phage tail tube protein	-
IRJ26_RS15780 (3007223)	3007223..3007312	-	90	WP_075058862.1	type I toxin-antitoxin system toxin BsrH	-
- (3007546)	3007546..3007768	+	223	NuclAT_0	-	Antitoxin
- (3007546)	3007546..3007768	+	223	NuclAT_0	-	Antitoxin
- (3007546)	3007546..3007768	+	223	NuclAT_0	-	Antitoxin
- (3007546)	3007546..3007768	+	223	NuclAT_0	-	Antitoxin
IRJ26_RS15785 (3007692)	3007692..3007871	-	180	WP_004398662.1	type I toxin-antitoxin system toxin TxpA	Toxin
IRJ26_RS15790 (3008017)	3008017..3008466	+	450	WP_003229933.1	phage portal protein	-
IRJ26_RS15795 (3008508)	3008508..3008645	+	138	WP_003229934.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	Similar MGE(s) Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE. Detail Genome accession Organism MGE type Related TA Coordinates Mash distance View NC_000964 Bacillus subtilis subsp. subtilis str. 168 Prophage TA006322, TA010201, TA020260 2645490..2699243 0.003	inside	Prophage	-	-	2983007..3038358	55351

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 60 a.a.
• Molecular weight: 6739.19 Da
• Isoelectric Point: 8.0370

>T180055 WP_004398662.1 NZ_CP064094:c3007871-3007692 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Nucleotide

• Length: 180 bp

>T180055 NZ_CP085060:393222-393572 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GTGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTT
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA

Antitoxin

Nucleotide

• Length: 223 bp

>AT180055 NZ_CP064094:3007546-3007768 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Structures

Toxin

• AlphaFold DB: A0A164X333

Antitoxin