Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 4084647..4084972 | Replicon | chromosome |
Accession | NZ_CP047325 | ||
Organism | Bacillus subtilis strain GOT9 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | P54373 |
Locus tag | GSY53_RS21000 | Protein ID | WP_004398662.1 |
Coordinates | 4084647..4084826 (+) | Length | 60 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 4084750..4084972 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
GSY53_RS20990 | 4083873..4084010 | - | 138 | WP_003229934.1 | hypothetical protein | - |
GSY53_RS20995 | 4084052..4084501 | - | 450 | WP_003229933.1 | phage portal protein | - |
GSY53_RS21000 | 4084647..4084826 | + | 180 | WP_004398662.1 | type I toxin-antitoxin system toxin TxpA | Toxin |
- | 4084750..4084972 | - | 223 | NuclAT_0 | - | Antitoxin |
- | 4084750..4084972 | - | 223 | NuclAT_0 | - | Antitoxin |
- | 4084750..4084972 | - | 223 | NuclAT_0 | - | Antitoxin |
- | 4084750..4084972 | - | 223 | NuclAT_0 | - | Antitoxin |
GSY53_RS21005 | 4085206..4085295 | + | 90 | WP_075058862.1 | type I toxin-antitoxin system toxin BsrH | - |
GSY53_RS21010 | 4085549..4085992 | - | 444 | WP_003229930.1 | phage tail tube protein | - |
GSY53_RS21015 | 4085995..4087395 | - | 1401 | WP_003229929.1 | phage tail sheath family protein | - |
GSY53_RS21020 | 4087396..4087587 | - | 192 | WP_010886574.1 | hypothetical protein | - |
GSY53_RS21025 | 4087584..4088021 | - | 438 | WP_003229927.1 | hypothetical protein | - |
GSY53_RS21030 | 4088034..4088537 | - | 504 | WP_003246050.1 | HK97 gp10 family phage protein | - |
GSY53_RS21035 | 4088534..4088896 | - | 363 | WP_003229925.1 | YqbH/XkdH family protein | - |
GSY53_RS21040 | 4088893..4089288 | - | 396 | WP_004398566.1 | DUF3199 family protein | - |
GSY53_RS21045 | 4089292..4089603 | - | 312 | WP_003229923.1 | YqbF domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | - | 4054160..4116406 | 62246 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 60 a.a. Molecular weight: 6739.19 Da Isoelectric Point: 8.0370
>T145978 WP_004398662.1 NZ_CP047325:4084647-4084826 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG
Download Length: 180 bp
>T145978 NZ_CP062713:c5059194-5059021 [Escherichia coli O157:H7]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG
Antitoxin
Download Length: 223 bp
>AT145978 NZ_CP047325:c4084972-4084750 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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