Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2659063..2659388 Replicon chromosome
Accession NZ_CP045821
Organism Bacillus subtilis strain MB8_B7

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag GII80_RS13935 Protein ID WP_004398662.1
Coordinates 2659063..2659242 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2659166..2659388 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GII80_RS13925 2658289..2658426 - 138 WP_003229934.1 hypothetical protein -
GII80_RS13930 2658468..2658917 - 450 WP_003229933.1 phage portal protein -
GII80_RS13935 2659063..2659242 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- 2659166..2659388 - 223 NuclAT_0 - Antitoxin
- 2659166..2659388 - 223 NuclAT_0 - Antitoxin
- 2659166..2659388 - 223 NuclAT_0 - Antitoxin
- 2659166..2659388 - 223 NuclAT_0 - Antitoxin
GII80_RS13940 2659622..2659711 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
GII80_RS13945 2659965..2660408 - 444 WP_003229930.1 phage tail tube protein -
GII80_RS13950 2660411..2661811 - 1401 WP_003229929.1 phage tail sheath family protein -
GII80_RS13955 2661812..2662003 - 192 WP_010886574.1 hypothetical protein -
GII80_RS13960 2662000..2662437 - 438 WP_003229927.1 hypothetical protein -
GII80_RS13965 2662450..2662953 - 504 WP_003246050.1 HK97 gp10 family phage protein -
GII80_RS13970 2662950..2663312 - 363 WP_003229925.1 YqbH/XkdH family protein -
GII80_RS13975 2663309..2663704 - 396 WP_004398566.1 DUF3199 family protein -
GII80_RS13980 2663708..2664019 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2628576..2683927 55351


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T142701 WP_004398662.1 NZ_CP045821:2659063-2659242 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

>T142701 NZ_CP060837:c4501593-4501282 [Salmonella enterica]
ATGCAATTTATAGAAACGGAACTCTTTACTGAAGATGTTAAAAAACTGCTCGATGATGATGAATACCATAAGCTTCAGGT
TTTTATGGCTCAGCATCCAGATTGTGGTGATGTCATTCAGGAAACGGGCGGCCTGAGAAAAATGCGCTGGGGAGCGCGAG
GCAAAGGAAAGCGTAGTGGCGTGCGAATTATCTATTTTCACCGTAGTCAACGGTATGAGATTCGCTTGCTTCTGATTTAT
CAAAAAGGCATTAAAGATGATCTCACGCCGCAGGAAAAAGCGGTGCTTCGTATGCTGAATGAGAGGTGGTAG

Antitoxin


Download         Length: 223 bp

>AT142701 NZ_CP045821:c2659388-2659166 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References