Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2537124..2537449 Replicon chromosome
Accession NZ_CP033205
Organism Bacillus subtilis strain MBI 600

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag DA787_RS13140 Protein ID WP_004398662.1
Coordinates 2537124..2537303 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2537227..2537449 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DA787_RS13130 2536350..2536487 - 138 WP_003229934.1 hypothetical protein -
DA787_RS13135 2536529..2536978 - 450 WP_003229933.1 phage portal protein -
DA787_RS13140 2537124..2537303 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- 2537227..2537449 - 223 NuclAT_0 - Antitoxin
- 2537227..2537449 - 223 NuclAT_0 - Antitoxin
- 2537227..2537449 - 223 NuclAT_0 - Antitoxin
- 2537227..2537449 - 223 NuclAT_0 - Antitoxin
DA787_RS13145 2537683..2537772 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
DA787_RS13150 2538026..2538469 - 444 WP_003229930.1 phage tail tube protein -
DA787_RS13155 2538472..2539872 - 1401 WP_003229929.1 phage tail sheath family protein -
DA787_RS13160 2539873..2540064 - 192 WP_010886574.1 hypothetical protein -
DA787_RS13165 2540061..2540498 - 438 WP_003229927.1 hypothetical protein -
DA787_RS13170 2540511..2541014 - 504 WP_003246050.1 HK97 gp10 family phage protein -
DA787_RS13175 2541011..2541373 - 363 WP_003229925.1 YqbH/XkdH family protein -
DA787_RS13180 2541370..2541765 - 396 WP_004398566.1 DUF3199 family protein -
DA787_RS13185 2541769..2542080 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2504374..2558127 53753


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T113400 WP_004398662.1 NZ_CP033205:2537124-2537303 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

>T113400 NZ_CP033205:2537124-2537303 [Bacillus subtilis]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin


Download         Length: 223 bp

>AT113400 NZ_CP033205:c2537449-2537227 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References