Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2677867..2678192 Replicon chromosome
Accession NZ_CP032310
Organism Bacillus subtilis strain WB800N

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag D3Z87_RS14210 Protein ID WP_004398662.1
Coordinates 2677867..2678046 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2677970..2678192 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D3Z87_RS14200 2677093..2677230 - 138 WP_003229934.1 hypothetical protein -
D3Z87_RS14205 2677272..2677721 - 450 WP_003229933.1 phage portal protein -
D3Z87_RS14210 2677867..2678046 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- 2677970..2678192 - 223 NuclAT_0 - Antitoxin
- 2677970..2678192 - 223 NuclAT_0 - Antitoxin
- 2677970..2678192 - 223 NuclAT_0 - Antitoxin
- 2677970..2678192 - 223 NuclAT_0 - Antitoxin
D3Z87_RS14215 2678426..2678515 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
D3Z87_RS14220 2678769..2679212 - 444 WP_003229930.1 phage tail tube protein -
D3Z87_RS14225 2679215..2680615 - 1401 WP_003229929.1 phage tail sheath family protein -
D3Z87_RS14230 2680616..2680807 - 192 WP_010886574.1 hypothetical protein -
D3Z87_RS14235 2680804..2681241 - 438 WP_003229927.1 hypothetical protein -
D3Z87_RS14240 2681254..2681757 - 504 WP_003246050.1 HK97 gp10 family phage protein -
D3Z87_RS14245 2681754..2682116 - 363 WP_003229925.1 YqbH/XkdH family protein -
D3Z87_RS14250 2682113..2682508 - 396 WP_004398566.1 DUF3199 family protein -
D3Z87_RS14255 2682512..2682823 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2647380..2698870 51490


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T111633 WP_004398662.1 NZ_CP032310:2677867-2678046 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

>T111633 NZ_CP032310:2677867-2678046 [Bacillus subtilis]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin


Download         Length: 223 bp

>AT111633 NZ_CP032310:c2678192-2677970 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References