MGE detailed information
MGE type: Conjugative plasmid MGE length: 134692 bp
Accession: NZ_LS999561 Location: 1..134692 Organism: Escherichia coli isolate EC-TO143 Replicon: plasmid 2
Accession: NZ_LS999561 Location: 1..134692 Organism: Escherichia coli isolate EC-TO143 Replicon: plasmid 2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ECTO143_RS24910 () | 96..729 | + | 634 | Protein_0 | conjugal transfer protein TraN | - |
| ECTO143_RS27225 () | 756..1015 | + | 260 | Protein_1 | conjugal transfer protein TrbE | - |
| ECTO143_RS24920 () | 1008..1758 | + | 751 | Protein_2 | type-F conjugative transfer system pilin assembly protein TraF | - |
| ECTO143_RS24925 () | 1774..2112 | + | 339 | WP_001287905.1 | conjugal transfer protein TrbA | - |
| ECTO143_RS24930 () | 2239..2524 | + | 286 | Protein_4 | type-F conjugative transfer system pilin chaperone TraQ | - |
| ECTO143_RS24935 () | 2511..3058 | + | 548 | Protein_5 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| ECTO143_RS24940 () | 2988..3329 | + | 342 | WP_001448115.1 | P-type conjugative transfer protein TrbJ | - |
| ECTO143_RS24945 () | 3277..3702 | + | 426 | WP_001448114.1 | F-type conjugal transfer protein TrbF | - |
| ECTO143_RS24950 () | 3689..5061 | + | 1373 | Protein_8 | conjugal transfer protein TraH | - |
| ECTO143_RS24955 () | 5058..7877 | + | 2820 | WP_001007057.1 | conjugal transfer mating pair stabilization protein TraG | - |
| ECTO143_RS24960 () | 7896..8393 | + | 498 | WP_000605861.1 | hypothetical protein | - |
| ECTO143_RS24965 () | 8425..9156 | + | 732 | WP_000850422.1 | complement resistance protein TraT | - |
| ECTO143_RS24975 () | 9428..10105 | + | 678 | WP_001339397.1 | IS66 family transposase ISCro1 | Transposase |
| ECTO143_RS24980 () | 10105..10452 | + | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| ECTO143_RS24985 () | 10472..12043 | + | 1572 | WP_001403908.1 | IS66 family transposase ISCro1 | Transposase |
| ECTO143_RS24990 () | 12116..14341 | + | 2226 | WP_052935733.1 | type IV conjugative transfer system coupling protein TraD | - |
| ECTO143_RS24995 () | 14341..19611 | + | 5271 | WP_000986934.1 | Multifunctional conjugation protein TraI | Relaxase |
| ECTO143_RS25000 () | 19631..20377 | + | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| ECTO143_RS25005 () | 20436..21296 | + | 861 | WP_000704528.1 | Quorum-quenching protein AidA | VF |
| ECTO143_RS25010 () | 21399..21959 | + | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| ECTO143_RS25015 () | 22088..22300 | + | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| ECTO143_RS25020 () | 22545..23006 | + | 462 | WP_001233838.1 | thermonuclease family protein | - |
| ECTO143_RS25025 () | 23052..23261 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| ECTO143_RS25030 () | 23299..23889 | + | 591 | WP_000766805.1 | DUF2726 domain-containing protein | - |
| ECTO143_RS25035 () | 24132..24836 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECTO143_RS25040 () | 25062..25877 | + | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| ECTO143_RS25050 () | 26224..28110 | + | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| ECTO143_RS25055 () | 28151..28678 | + | 528 | WP_000178050.1 | iron transporter | - |
| ECTO143_RS25060 () | 28782..30161 | + | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| ECTO143_RS25065 () | 30164..31447 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| ECTO143_RS25070 () | 31437..32567 | + | 1131 | WP_000729220.1 | ABC transporter permease | - |
| ECTO143_RS25075 () | 32572..33267 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| ECTO143_RS25080 () | 33254..33739 | + | 486 | WP_001267177.1 | TlpA family protein disulfide reductase | - |
| ECTO143_RS25085 () | 33764..34249 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| ECTO143_RS25090 () | 34371..34901 | + | 531 | Protein_34 | histidine-type phosphatase | - |
| ECTO143_RS25095 () | 34959..35663 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECTO143_RS25100 () | 35727..35867 | - | 141 | Protein_36 | metal ABC transporter permease | - |
| ECTO143_RS25105 () | 35864..36721 | - | 858 | WP_001101723.1 | iron/manganese ABC transporter permease subunit SitC | - |
| ECTO143_RS25110 () | 36718..37545 | - | 828 | WP_000983710.1 | Manganese transport system ATP-binding protein MntB | VF |
| ECTO143_RS25115 () | 37545..38459 | - | 915 | WP_000949004.1 | putative periplasmic iron-binding protein | VF |
| ECTO143_RS25125 () | 38815..39512 | + | 698 | Protein_40 | IS1 family transposase | - |
| ECTO143_RS25130 () | 39766..40788 | - | 1023 | WP_000361402.1 | helicase UvrD | - |
| ECTO143_RS25135 () | 40773..42338 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
| ECTO143_RS25140 () | 42413..42829 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| ECTO143_RS25145 () | 42826..43056 | - | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| ECTO143_RS25150 () | 43437..47231 | + | 3795 | WP_001144732.1 | hypothetical protein | - |
| ECTO143_RS25155 () | 47276..47692 | - | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| ECTO143_RS25160 () | 47689..47919 | - | 231 | WP_001261278.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| ECTO143_RS25165 () | 48184..48684 | + | 501 | WP_000528932.1 | hypothetical protein | - |
| ECTO143_RS25170 () | 48697..49470 | + | 774 | WP_000905949.1 | hypothetical protein | - |
| ECTO143_RS25175 () | 49681..51294 | - | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| ECTO143_RS25180 () | 51325..51675 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| ECTO143_RS25185 () | 51672..52097 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| ECTO143_RS25190 () | 52159..53310 | + | 1152 | WP_031325939.1 | DUF3800 domain-containing protein | - |
| ECTO143_RS25195 () | 53344..53856 | - | 513 | WP_000151784.1 | hypothetical protein | - |
| ECTO143_RS25200 () | 54376..54726 | + | 351 | WP_000493379.1 | hypothetical protein | - |
| ECTO143_RS25205 () | 54770..55459 | + | 690 | WP_000796228.1 | hypothetical protein | - |
| ECTO143_RS25210 () | 55456..56247 | + | 792 | WP_000016493.1 | site-specific integrase | - |
| ECTO143_RS25215 () | 56425..56778 | + | 354 | WP_000864812.1 | colicin M immunity protein | - |
| ECTO143_RS25220 () | 56828..57643 | - | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| ECTO143_RS25230 () | 57887..58414 | + | 528 | WP_000203272.1 | colicin B immunity protein | - |
| ECTO143_RS25235 () | 58432..58599 | - | 168 | Protein_61 | colicin-B | - |
| ECTO143_RS25240 () | 58772..59053 | + | 282 | WP_001105066.1 | hypothetical protein | - |
| ECTO143_RS25245 () | 59532..59768 | + | 237 | WP_014640552.1 | colicin V immunity protein | - |
| ECTO143_RS25250 () | 59789..60486 | - | 698 | Protein_64 | IS1 family transposase | - |
| ECTO143_RS25255 () | 60536..60895 | + | 360 | Protein_65 | ISNCY family transposase | - |
| ECTO143_RS25260 () | 60973..61670 | - | 698 | Protein_66 | IS1 family transposase | - |
| ECTO143_RS25265 () | 61727..61995 | + | 269 | Protein_67 | IS3 family transposase ISLad1 | Transposase |
| ECTO143_RS25275 () | 63540..63698 | + | 159 | WP_001312823.1 | integrase core domain-containing protein | - |
| ECTO143_RS25290 () | 64971..65924 | + | 954 | WP_000280980.1 | Protease 7 | VF |
| ECTO143_RS25300 () | 66357..67466 | + | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| ECTO143_RS25305 () | 67535..68437 | + | 903 | WP_001312822.1 | antimicrobial resistance protein Mig-14 | - |
| ECTO143_RS25310 () | 68811..68999 | + | 189 | WP_014640565.1 | hypothetical protein | - |
| ECTO143_RS25315 () | 69120..69860 | + | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| ECTO143_RS25320 () | 70145..71122 | - | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| ECTO143_RS25330 () | 73129..73452 | + | 324 | Protein_77 | IS21 family transposase IS21 | Transposase |
| ECTO143_RS25335 () | 73454..73558 | + | 105 | Protein_78 | AAA family ATPase | - |
| ECTO143_RS25340 () | 73619..74132 | + | 514 | Protein_79 | DUF4113 domain-containing protein | - |
| ECTO143_RS25345 () | 74312..75009 | - | 698 | Protein_80 | IS1 family transposase | - |
| ECTO143_RS25355 () | 75365..76279 | + | 915 | WP_000949004.1 | putative periplasmic iron-binding protein | VF |
| ECTO143_RS25360 () | 76279..77106 | + | 828 | WP_000983710.1 | Manganese transport system ATP-binding protein MntB | VF |
| ECTO143_RS25365 () | 77103..77960 | + | 858 | WP_000992806.1 | Manganese transport system membrane protein MntB | ARG |
| ECTO143_RS25370 () | 77957..78814 | + | 858 | WP_000968140.1 | Manganese transport system membrane protein MntB | ARG |
| ECTO143_RS25375 () | 79048..79305 | - | 258 | Protein_85 | Tn3 family transposase | - |
| ECTO143_RS25380 () | 79303..79434 | + | 132 | Protein_86 | phosphopyruvate hydratase | - |
| ECTO143_RS25385 () | 79431..79658 | - | 228 | Protein_87 | malate dehydrogenase | - |
| ECTO143_RS25395 () | 80098..80577 | - | 480 | WP_000190053.1 | hypothetical protein | - |
| ECTO143_RS25400 () | 80695..80967 | + | 273 | Protein_89 | hypothetical protein | - |
| ECTO143_RS25405 () | 81021..81718 | + | 698 | Protein_90 | IS1 family transposase | - |
| ECTO143_RS25410 () | 81653..82009 | - | 357 | WP_134089488.1 | PAS domain-containing protein | - |
| ECTO143_RS25415 () | 82203..82586 | - | 384 | WP_001151564.1 | relaxosome protein TraM | - |
| ECTO143_RS25420 () | 82872..83519 | + | 648 | WP_000614282.1 | hypothetical protein | VF |
| ECTO143_RS25425 () | 83816..84637 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| ECTO143_RS25430 () | 84758..85045 | - | 288 | WP_000107537.1 | hypothetical protein | - |
| ECTO143_RS25455 () | 85964..86122 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 86166..86390 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 86166..86390 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 86166..86390 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 86166..86390 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| ECTO143_RS27070 () | 86202..86390 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| ECTO143_RS25460 () | 86402..87121 | - | 720 | WP_001276228.1 | plasmid SOS inhibition protein A | - |
| ECTO143_RS25465 () | 87118..87552 | - | 435 | WP_000845901.1 | conjugation system SOS inhibitor PsiB | - |
| ECTO143_RS25470 () | 87607..89565 | - | 1959 | WP_001145469.1 | ParB/RepB/Spo0J family partition protein | - |
| ECTO143_RS25475 () | 89624..89857 | - | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| ECTO143_RS25480 () | 89913..90440 | - | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| ECTO143_RS25505 () | 90910..91158 | - | 249 | WP_071606928.1 | hypothetical protein | - |
| ECTO143_RS25515 () | 91310..91873 | - | 564 | WP_012783964.1 | class I SAM-dependent methyltransferase | - |
| ECTO143_RS25520 () | 91920..93281 | - | 1362 | WP_021538345.1 | DUF3560 domain-containing protein | - |
| ECTO143_RS25525 () | 93333..93563 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| ECTO143_RS27230 () | 94241..94569 | + | 329 | Protein_107 | pilus assembly protein | - |
| ECTO143_RS25545 () | 94557..94739 | - | 183 | WP_001027505.1 | hypothetical protein | - |
| ECTO143_RS25550 () | 94739..95200 | - | 462 | WP_042007484.1 | DUF1380 family protein | - |
| ECTO143_RS25555 () | 95200..95502 | - | 303 | WP_072256028.1 | antirestriction protein | - |
| ECTO143_RS25565 () | 96027..96998 | + | 972 | WP_000082154.1 | IS110 family transposase ISEc32 | Transposase |
| ECTO143_RS25570 () | 97051..97748 | - | 698 | Protein_112 | IS1 family transposase | - |
| ECTO143_RS25575 () | 97802..98134 | - | 333 | Protein_113 | hypothetical protein | - |
| ECTO143_RS27235 () | 98203..98541 | - | 339 | WP_001513511.1 | hypothetical protein | - |
| ECTO143_RS25590 () | 99353..100324 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| ECTO143_RS25595 () | 100324..101490 | - | 1167 | WP_001238646.1 | hypothetical protein | VF |
| ECTO143_RS25600 () | 101790..102487 | - | 698 | Protein_117 | IS1 family transposase | - |
| ECTO143_RS25605 () | 102590..102961 | + | 372 | WP_085334599.1 | hypothetical protein | - |
| ECTO143_RS25610 () | 103055..103282 | + | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| ECTO143_RS25615 () | 103316..103678 | + | 363 | WP_001098998.1 | type IV conjugative transfer system pilin TraA | - |
| ECTO143_RS25620 () | 103683..103994 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| ECTO143_RS25625 () | 104016..104582 | + | 567 | WP_000399804.1 | type IV conjugative transfer system protein TraE | - |
| ECTO143_RS25630 () | 104593..105297 | + | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| ECTO143_RS25635 () | 105297..106724 | + | 1428 | WP_000146638.1 | conjugal transfer protein TraB | - |
| ECTO143_RS25640 () | 106714..107298 | + | 585 | WP_000002795.1 | conjugal transfer protein TraP | - |
| ECTO143_RS25645 () | 107252..107605 | + | 354 | WP_071528018.1 | conjugal transfer protein TrbD | - |
| ECTO143_RS25650 () | 107598..107849 | + | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| ECTO143_RS25655 () | 107846..108361 | + | 516 | WP_000809893.1 | type IV conjugative transfer system lipoprotein TraV | - |
| ECTO143_RS25660 () | 108496..108717 | + | 222 | WP_001278978.1 | conjugal transfer protein TraR | - |
| ECTO143_RS25665 () | 108877..111504 | + | 2628 | WP_001064239.1 | type IV secretion system protein TraC | - |
| ECTO143_RS25670 () | 111501..111887 | + | 387 | WP_000214082.1 | type-F conjugative transfer system protein TrbI | - |
| ECTO143_RS25675 () | 111884..112516 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| ECTO143_RS25680 () | 112513..113505 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| ECTO143_RS25685 () | 113535..113840 | + | 306 | WP_000224411.1 | hypothetical protein | - |
| ECTO143_RS25690 () | 113849..114487 | + | 639 | WP_001080257.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| ECTO143_RS25695 () | 114484..116292 | + | 1809 | WP_000821863.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| ECTO143_RS25700 () | 116319..116576 | + | 258 | WP_000864320.1 | conjugal transfer protein TrbE | - |
| ECTO143_RS25705 () | 116569..117312 | + | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| ECTO143_RS25710 () | 117328..117666 | + | 339 | WP_001287905.1 | conjugal transfer protein TrbA | - |
| ECTO143_RS25715 () | 117793..118077 | + | 285 | WP_001448202.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| ECTO143_RS25720 () | 118064..118609 | + | 546 | WP_000059824.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| ECTO143_RS25725 () | 118539..118880 | + | 342 | WP_001448115.1 | P-type conjugative transfer protein TrbJ | - |
| ECTO143_RS25730 () | 118828..119253 | + | 426 | WP_001448114.1 | F-type conjugal transfer protein TrbF | - |
| ECTO143_RS25735 () | 119240..120613 | + | 1374 | WP_001137364.1 | conjugal transfer protein TraH | - |
| ECTO143_RS25740 () | 120610..123429 | + | 2820 | WP_001007057.1 | conjugal transfer mating pair stabilization protein TraG | - |
| ECTO143_RS25745 () | 123448..123945 | + | 498 | WP_000605861.1 | hypothetical protein | - |
| ECTO143_RS25750 () | 123977..124708 | + | 732 | WP_000850422.1 | complement resistance protein TraT | - |
| ECTO143_RS25760 () | 124980..125657 | + | 678 | WP_001339397.1 | IS66 family transposase ISCro1 | Transposase |
| ECTO143_RS25765 () | 125657..126004 | + | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| ECTO143_RS25770 () | 126024..127595 | + | 1572 | WP_001403908.1 | IS66 family transposase ISCro1 | Transposase |
| ECTO143_RS25775 () | 127668..129893 | + | 2226 | WP_052935733.1 | type IV conjugative transfer system coupling protein TraD | - |
| ECTO143_RS25780 () | 129893..134692 | + | 4800 | Protein_152 | Multifunctional conjugation protein TraI | Relaxase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|