MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 133139 bp
Accession: NZ_LS992191 Location: 1..133139 Organism: Escherichia coli isolate Escherichia coli str. TO148 Replicon: plasmid 2
Accession: NZ_LS992191 Location: 1..133139 Organism: Escherichia coli isolate Escherichia coli str. TO148 Replicon: plasmid 2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ECTO148_RS25545 () | 3..3467 | + | 3465 | Protein_0 | hypothetical protein | Relaxase |
| ECTO148_RS25550 () | 3487..4233 | + | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| ECTO148_RS25555 () | 4292..5152 | + | 861 | WP_000704523.1 | hypothetical protein | VF |
| ECTO148_RS25560 () | 5255..5815 | + | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| ECTO148_RS25565 () | 5944..6156 | + | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| ECTO148_RS25570 () | 6436..7133 | + | 698 | Protein_5 | IS1 family transposase | - |
| ECTO148_RS25575 () | 7178..7639 | + | 462 | WP_001233838.1 | thermonuclease family protein | - |
| ECTO148_RS25580 () | 7685..7894 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| ECTO148_RS25585 () | 7932..8522 | + | 591 | WP_000766807.1 | DUF2726 domain-containing protein | - |
| ECTO148_RS25590 () | 8762..9016 | + | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
| ECTO148_RS25600 () | 9254..9328 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| ECTO148_RS25605 () | 9321..10178 | + | 858 | WP_000130646.1 | incFII family plasmid replication initiator RepA | - |
| ECTO148_RS25615 () | 11117..11770 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| ECTO148_RS25620 () | 11863..12120 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| ECTO148_RS25625 () | 12053..12454 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| ECTO148_RS25630 () | 12591..15488 | - | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| ECTO148_RS25635 () | 15583..16188 | + | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| ECTO148_RS25640 () | 16212..16961 | - | 750 | Protein_17 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| ECTO148_RS25645 () | 16950..17357 | + | 408 | WP_001214976.1 | cysteine hydrolase | - |
| ECTO148_RS25650 () | 17495..18379 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| ECTO148_RS25655 () | 18411..19610 | - | 1200 | WP_000804064.1 | hypothetical protein | ARG |
| ECTO148_RS25660 () | 19716..20366 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| ECTO148_RS25665 () | 20398..20640 | - | 243 | WP_032140899.1 | hypothetical protein | - |
| ECTO148_RS25670 () | 20682..22196 | - | 1515 | Protein_23 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| ECTO148_RS25675 () | 22262..22966 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECTO148_RS25680 () | 23110..23664 | + | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| ECTO148_RS25685 () | 23795..24625 | + | 831 | WP_001334766.1 | hypothetical protein | ARG |
| ECTO148_RS25690 () | 24763..25203 | + | 441 | Protein_27 | CatB-related O-acetyltransferase | - |
| ECTO148_RS25695 () | 25257..25961 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECTO148_RS25700 () | 26026..28269 | - | 2244 | Protein_29 | Tn3 family transposase TnpA_Tn3 | Transposase |
| ECTO148_RS25705 () | 28283..28615 | + | 333 | WP_001393253.1 | WbuC family cupin fold metalloprotein | - |
| ECTO148_RS25710 () | 28662..29537 | - | 876 | WP_000239590.1 | hypothetical protein | ARG |
| ECTO148_RS25715 () | 29673..30377 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECTO148_RS26590 () | 30418..30597 | - | 180 | Protein_33 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| ECTO148_RS25725 () | 30723..31073 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| ECTO148_RS25735 () | 31276..32289 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| ECTO148_RS25740 () | 32447..32920 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| ECTO148_RS25745 () | 33051..33839 | + | 789 | WP_000503573.1 | hypothetical protein | ARG |
| ECTO148_RS25750 () | 34045..34392 | + | 348 | WP_000679427.1 | Spermidine export protein MdtJ | ARG |
| ECTO148_RS25755 () | 34386..35225 | + | 840 | WP_000259031.1 | hypothetical protein | ARG |
| ECTO148_RS25765 () | 35353..35556 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| ECTO148_RS25770 () | 35712..36917 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| ECTO148_RS25775 () | 36928..37233 | + | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| ECTO148_RS26595 () | 37277..37342 | + | 66 | Protein_43 | EAL domain-containing protein | - |
| ECTO148_RS25785 () | 37460..38224 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| ECTO148_RS25800 () | 38717..39301 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| ECTO148_RS25805 () | 39301..40539 | - | 1239 | WP_000004159.1 | MFS transporter | - |
| ECTO148_RS25810 () | 40536..41441 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| ECTO148_RS25820 () | 41563..42267 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECTO148_RS25825 () | 42493..43308 | + | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| ECTO148_RS25835 () | 43655..45541 | + | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| ECTO148_RS25840 () | 45582..46109 | + | 528 | WP_000178050.1 | iron transporter | - |
| ECTO148_RS25845 () | 46213..47592 | + | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| ECTO148_RS25850 () | 47595..48878 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| ECTO148_RS25855 () | 48868..49998 | + | 1131 | WP_000729220.1 | ABC transporter permease | - |
| ECTO148_RS25860 () | 50003..50698 | + | 696 | WP_000117262.1 | hypothetical protein | VF |
| ECTO148_RS25865 () | 50685..51170 | + | 486 | WP_001267177.1 | TlpA family protein disulfide reductase | - |
| ECTO148_RS25870 () | 51195..51680 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| ECTO148_RS25875 () | 51802..52332 | + | 531 | Protein_58 | histidine-type phosphatase | - |
| ECTO148_RS25880 () | 52390..53094 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECTO148_RS25885 () | 53119..54315 | + | 1197 | Protein_60 | IS3 family transposase | - |
| ECTO148_RS25890 () | 54337..54570 | + | 234 | Protein_61 | Tn3 family transposase ISPsy39 | Transposase |
| ECTO148_RS25895 () | 54647..54955 | + | 309 | Protein_62 | IS4 family transposase ISEc13 | Transposase |
| ECTO148_RS25900 () | 55014..56324 | - | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| ECTO148_RS25905 () | 56317..57390 | - | 1074 | WP_000950177.1 | hypothetical protein | VF |
| ECTO148_RS25910 () | 57396..58220 | - | 825 | WP_000922702.1 | phosphodiesterase | - |
| ECTO148_RS25915 () | 58231..59118 | - | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| ECTO148_RS25920 () | 59108..59986 | - | 879 | WP_000338039.1 | sugar ABC transporter permease | - |
| ECTO148_RS25925 () | 60117..60557 | - | 441 | Protein_68 | zinc-binding dehydrogenase | - |
| ECTO148_RS25935 () | 60958..61848 | + | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| ECTO148_RS25940 () | 61873..62253 | + | 381 | WP_000710783.1 | Rid family detoxifying hydrolase | - |
| ECTO148_RS25945 () | 62286..63251 | + | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| ECTO148_RS25950 () | 63297..64049 | - | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| ECTO148_RS25955 () | 64654..64938 | + | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| ECTO148_RS25960 () | 64938..65213 | + | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| ECTO148_RS25965 () | 65319..65612 | + | 294 | WP_001105060.1 | hypothetical protein | - |
| ECTO148_RS25970 () | 65647..65775 | - | 129 | Protein_76 | IS481 family transposase | - |
| ECTO148_RS25975 () | 65808..66977 | - | 1170 | WP_001072355.1 | hypothetical protein | - |
| ECTO148_RS25985 () | 67470..67777 | + | 308 | Protein_78 | type II toxin-antitoxin system ParD family antitoxin | - |
| ECTO148_RS25995 () | 68066..68763 | + | 698 | Protein_79 | IS1 family transposase IS1S | Transposase |
| ECTO148_RS26000 () | 69017..70039 | - | 1023 | WP_000361402.1 | helicase UvrD | - |
| ECTO148_RS26005 () | 70024..71589 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
| ECTO148_RS26010 () | 71664..72080 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| ECTO148_RS26015 () | 72077..72307 | - | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| ECTO148_RS26020 () | 72688..76482 | + | 3795 | WP_001144732.1 | hypothetical protein | - |
| ECTO148_RS26025 () | 76527..76943 | - | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| ECTO148_RS26030 () | 76940..77170 | - | 231 | WP_001261278.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| ECTO148_RS26035 () | 77435..77935 | + | 501 | WP_000528932.1 | hypothetical protein | - |
| ECTO148_RS26040 () | 77948..78721 | + | 774 | WP_000905949.1 | hypothetical protein | - |
| ECTO148_RS26045 () | 78932..80545 | - | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| ECTO148_RS26050 () | 80576..80926 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| ECTO148_RS26055 () | 80923..81348 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| ECTO148_RS26060 () | 81410..82561 | + | 1152 | WP_031325939.1 | DUF3800 domain-containing protein | - |
| ECTO148_RS26065 () | 82595..83107 | - | 513 | WP_000151784.1 | hypothetical protein | - |
| ECTO148_RS26070 () | 83653..83871 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| ECTO148_RS26075 () | 83873..84178 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| ECTO148_RS26080 () | 84179..84985 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| ECTO148_RS26085 () | 85759..86514 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| ECTO148_RS26090 () | 87102..88268 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| ECTO148_RS26095 () | 88268..89239 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| ECTO148_RS26110 () | 90106..91008 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| ECTO148_RS26115 () | 91012..91316 | + | 305 | Protein_101 | hypothetical protein | - |
| ECTO148_RS26120 () | 91393..92076 | + | 684 | WP_000086185.1 | DNA methylase | - |
| ECTO148_RS26125 () | 92077..92298 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| ECTO148_RS26130 () | 92312..92746 | + | 435 | WP_000274437.1 | DUF1380 family protein | - |
| ECTO148_RS26135 () | 92797..93573 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| ECTO148_RS26145 () | 94113..94415 | + | 303 | WP_001671341.1 | antirestriction protein | - |
| ECTO148_RS26150 () | 94462..94884 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| ECTO148_RS26155 () | 94881..95072 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| ECTO148_RS26165 () | 96107..96337 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| ECTO148_RS26170 () | 96389..97750 | + | 1362 | WP_000170728.1 | DUF3560 domain-containing protein | - |
| ECTO148_RS26175 () | 97797..98360 | + | 564 | WP_012783964.1 | class I SAM-dependent methyltransferase | - |
| ECTO148_RS26205 () | 99876..100355 | + | 480 | Protein_112 | group II intron reverse transcriptase/maturase | - |
| ECTO148_RS26215 () | 100408..101112 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| ECTO148_RS26220 () | 101177..102016 | + | 840 | Protein_114 | conjugal transfer pilus assembly protein TraU | - |
| ECTO148_RS26225 () | 102046..102351 | + | 306 | WP_000224416.1 | hypothetical protein | - |
| ECTO148_RS26230 () | 102360..102998 | + | 639 | WP_001080256.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| ECTO148_RS26235 () | 102995..104845 | + | 1851 | WP_000821856.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| ECTO148_RS26240 () | 104872..105129 | + | 258 | WP_000864353.1 | conjugal transfer protein TrbE | - |
| ECTO148_RS26245 () | 105122..105865 | + | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| ECTO148_RS26250 () | 105879..106223 | + | 345 | WP_000556796.1 | conjugal transfer protein TrbA | - |
| ECTO148_RS26255 () | 106342..106626 | + | 285 | WP_000624194.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| ECTO148_RS26260 () | 106613..107158 | + | 546 | WP_000059831.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| ECTO148_RS26265 () | 107088..107435 | + | 348 | WP_001309242.1 | P-type conjugative transfer protein TrbJ | - |
| ECTO148_RS26270 () | 107383..107808 | + | 426 | WP_001444237.1 | F-type conjugal transfer protein TrbF | - |
| ECTO148_RS26275 () | 107795..109168 | + | 1374 | WP_000944331.1 | conjugal transfer protein TraH | - |
| ECTO148_RS26280 () | 109165..111987 | + | 2823 | WP_001007039.1 | conjugal transfer mating pair stabilization protein TraG | - |
| ECTO148_RS26285 () | 112003..112488 | + | 486 | WP_000605870.1 | hypothetical protein | - |
| ECTO148_RS26290 () | 112537..113268 | + | 732 | WP_000782451.1 | complement resistance protein TraT | - |
| ECTO148_RS26295 () | 113471..114208 | + | 738 | WP_000199905.1 | hypothetical protein | - |
| ECTO148_RS26300 () | 114277..115848 | - | 1572 | WP_000381395.1 | IS66 family transposase ISCro1 | Transposase |
| ECTO148_RS26305 () | 115868..116215 | - | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| ECTO148_RS26310 () | 116215..116892 | - | 678 | WP_001339397.1 | IS66 family transposase ISCro1 | Transposase |
| ECTO148_RS26315 () | 116966..119173 | + | 2208 | WP_001617742.1 | type IV conjugative transfer system coupling protein TraD | - |
| ECTO148_RS26320 () | 119173..124443 | + | 5271 | WP_000948354.1 | hypothetical protein | Relaxase |
| ECTO148_RS26325 () | 124463..125209 | + | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| ECTO148_RS26330 () | 125268..126128 | + | 861 | WP_000704523.1 | hypothetical protein | VF |
| ECTO148_RS26335 () | 126231..126791 | + | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| ECTO148_RS26340 () | 126995..127177 | + | 183 | WP_134087830.1 | hypothetical protein | - |
| ECTO148_RS26345 () | 127411..128108 | + | 698 | Protein_139 | IS1 family transposase | - |
| ECTO148_RS26350 () | 128153..128614 | + | 462 | WP_001233838.1 | thermonuclease family protein | - |
| ECTO148_RS26355 () | 128659..128868 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| ECTO148_RS26360 () | 128906..129496 | + | 591 | WP_000766807.1 | DUF2726 domain-containing protein | - |
| ECTO148_RS26365 () | 129736..129990 | + | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
| ECTO148_RS26375 () | 130228..130302 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| ECTO148_RS26380 () | 130295..131152 | + | 858 | Protein_145 | incFII family plasmid replication initiator RepA | - |
| ECTO148_RS26600 () | 131853..132095 | + | 243 | WP_172599424.1 | hypothetical protein | - |
| ECTO148_RS26390 () | 132092..132751 | + | 660 | Protein_147 | CPBP family intramembrane metalloprotease | - |
| ECTO148_RS26395 () | 132843..133102 | + | 260 | Protein_148 | antitoxin | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|