NZ_LR8902101..197166

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 197166 bp
Accession: NZ_LR890210        Location: 1..197166         Organism: Klebsiella pneumoniae isolate INF022-sc-2279895       Replicon: plasmid 2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW18_RS25650 () 1..1011 + 1011 WP_000200070.1 RepB family plasmid replication initiator protein -
JMW18_RS25655 () 1709..2449 - 741 WP_001515717.1 tyrosine-type recombinase/integrase -
JMW18_RS25660 () 3080..3388 - 309 Protein_2 IS3 family transposase ISLad1 Transposase
JMW18_RS25665 () 3405..4481 - 1077 WP_000227969.1 IS110 family transposase ISEc21 Transposase
JMW18_RS25670 () 4763..5622 - 860 Protein_4 IS3 family transposase -
JMW18_RS25675 () 5976..6224 + 249 WP_004187025.1 plasmid stabilization protein -
JMW18_RS25680 () 6214..6402 + 189 Protein_6 type II toxin-antitoxin system RelE/ParE family toxin -
JMW18_RS25685 () 6458..7155 + 698 Protein_7 IS1 family transposase IS1R Transposase
JMW18_RS25690 () 7313..7711 + 399 Protein_8 DNA-binding response regulator -
JMW18_RS25695 () 7864..8844 - 981 WP_000082736.1 IS5 family transposase ISEc68 Transposase
JMW18_RS25700 () 8913..9179 + 267 Protein_10 response regulator transcription factor -
JMW18_RS25705 () 9375..10343 - 969 WP_072196505.1 IS5 family transposase IS903B Transposase
JMW18_RS25710 () 10668..11276 + 609 WP_025714801.1 hypothetical protein VF
JMW18_RS25715 () 11372..12073 + 702 WP_000820818.1 putative fimbrial chaperone YadV VF
JMW18_RS25720 () 12085..14571 + 2487 WP_000813718.1 Outer membrane usher protein HtrE VF
JMW18_RS25725 () 14562..15557 + 996 WP_049087407.1 Fimbria adhesin protein VF
JMW18_RS25730 () 15571..16206 + 636 WP_000677445.1 hypothetical protein VF
JMW18_RS25735 () 16241..16957 - 717 WP_004149658.1 Cyclic di-GMP phosphodiesterase PdeH VF
JMW18_RS25740 () 17291..18271 - 981 WP_014386491.1 IS5 family transposase ISKpn26 Transposase
JMW18_RS25745 () 18342..18572 - 231 Protein_19 hypothetical protein -
JMW18_RS25750 () 18529..18759 + 231 WP_001261282.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin Detail
JMW18_RS25755 () 18756..19172 + 417 WP_001044770.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
JMW18_RS25760 () 19246..20808 + 1563 WP_009309907.1 AAA family ATPase -
JMW18_RS25765 () 20793..21815 + 1023 WP_000361404.1 helicase UvrD -
JMW18_RS25770 () 22359..23267 + 909 WP_032425603.1 HNH endonuclease -
JMW18_RS25775 () 23453..23803 - 351 WP_004187110.1 DUF305 domain-containing protein -
JMW18_RS25780 () 23951..24382 - 432 WP_020803533.1 silver-binding protein SilE -
JMW18_RS25785 () 24633..26108 - 1476 WP_003032875.1 copper/silver sensor histidine kinase SilS -
JMW18_RS25790 () 26101..26781 - 681 WP_001572351.1 Transcriptional regulatory protein CusR VF
JMW18_RS25795 () 26971..28356 + 1386 WP_000475512.1 Cation efflux system protein CusC VF
JMW18_RS25800 () 28385..28738 + 354 WP_001246153.1 cation efflux system protein CusF -
JMW18_RS25805 () 28852..30144 + 1293 WP_004152079.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
JMW18_RS25810 () 30155..33301 + 3147 WP_004098958.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
JMW18_RS25815 () 33388..33828 + 441 WP_008322815.1 hypothetical protein -
JMW18_RS25820 () 33955..36402 + 2448 WP_020803531.1 Ag(+)-translocating P-type ATPase SilP -
JMW18_RS25825 () 36443..36640 + 198 WP_000843497.1 DUF2933 domain-containing protein -
JMW18_RS25830 () 36674..37411 - 738 WP_004118669.1 Murein DD-endopeptidase MepM VF
JMW18_RS25835 () 37700..38149 - 450 WP_001023257.1 copper resistance protein -
JMW18_RS25840 () 38383..40200 + 1818 WP_000925242.1 multicopper oxidase PcoA -
JMW18_RS25845 () 40206..41096 + 891 WP_020803534.1 copper resistance outer membrane transporter PcoB -
JMW18_RS25850 () 41136..41516 + 381 WP_000025662.1 copper resistance system metallochaperone PcoC -
JMW18_RS25855 () 41521..42450 + 930 WP_020805562.1 copper resistance inner membrane protein PcoD -
JMW18_RS25860 () 42505..43185 + 681 WP_001188930.1 Transcriptional activator protein CopR VF
JMW18_RS25865 () 43182..44582 + 1401 WP_002436614.1 copper resistance membrane spanning protein PcoS -
JMW18_RS25870 () 44798..45199 + 402 Protein_44 copper-binding protein -
JMW18_RS25875 () 45226..46764 - 1539 WP_023290558.1 IS66 family transposase ISKpn24 Transposase
JMW18_RS25880 () 46813..47160 - 348 WP_000612626.1 IS66 family transposase ISKpn24 Transposase
JMW18_RS25885 () 47157..47561 - 405 WP_023290559.1 IS66 family transposase ISKpn24 Transposase
JMW18_RS25890 () 48073..48171 - 99 WP_004118688.1 type II toxin-antitoxin system RelE/ParE family toxin -
JMW18_RS25895 () 48158..48337 - 180 WP_004118349.1 type II toxin-antitoxin system ParD family antitoxin -
JMW18_RS25900 () 48651..48914 + 264 WP_004118691.1 hypothetical protein -
JMW18_RS25905 () 48911..49477 + 567 WP_042922197.1 hypothetical protein -
JMW18_RS25910 () 49508..50002 + 495 WP_016528789.1 hypothetical protein -
JMW18_RS25915 () 50063..50266 + 204 WP_004150739.1 hemolysin expression modulator Hha -
JMW18_RS25920 () 50315..50572 + 258 WP_004098928.1 hypothetical protein -
JMW18_RS25925 () 50648..50902 + 255 WP_032425571.1 hypothetical protein -
JMW18_RS25930 () 51078..51344 + 267 WP_020804426.1 DUF1778 domain-containing protein Antitoxin Detail
JMW18_RS25935 () 51332..51814 + 483 WP_004098919.1 GNAT family N-acetyltransferase Toxin Detail
JMW18_RS25940 () 52015..53418 + 1404 WP_001567368.1 ISNCY family transposase ISKpn21 Transposase
JMW18_RS25945 () 53447..54079 - 633 WP_001567369.1 hypothetical protein -
JMW18_RS25950 () 54300..55016 + 717 Protein_60 IS3 family transposase ISKpn38 Transposase
JMW18_RS25955 () 55298..56161 - 864 WP_020803592.1 toll/interleukin-1 receptor domain-containing protein -
JMW18_RS25960 () 56178..56636 - 459 WP_077252872.1 hypothetical protein -
JMW18_RS25965 () 57043..57903 + 861 Protein_63 IS110 family transposase IS1663 Transposase
JMW18_RS25970 () 58140..59222 + 1083 WP_004152286.1 DNA-binding transcriptional repressor LacI -
JMW18_RS25975 () 59344..62418 + 3075 WP_004118823.1 beta-galactosidase -
JMW18_RS25980 () 62470..63723 + 1254 WP_004118826.1 lactose permease -
JMW18_RS25985 () 63789..63929 + 141 Protein_67 galactoside O-acetyltransferase -
JMW18_RS25990 () 63944..64638 - 695 Protein_68 IS1 family transposase IS1S Transposase
JMW18_RS25995 () 64815..65519 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
JMW18_RS26000 () 65573..65824 - 252 Protein_70 Tn3 family transposase TnpA_Tn5403 Transposase
JMW18_RS26005 () 65919..66524 + 606 WP_000509966.1 Tn3 family transposase TnpR_Tn5403 Transposase
JMW18_RS26010 () 66552..66659 + 108 Protein_72 acetamidase -
JMW18_RS26015 () 66667..68400 + 1734 WP_004118832.1 Glutathione import ATP-binding protein GsiA VF
JMW18_RS26020 () 68723..69427 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
JMW18_RS26025 () 69661..70358 - 698 Protein_75 IS1 family transposase IS1R Transposase
JMW18_RS26030 () 70628..71773 + 1146 WP_001325018.1 ABC transporter permease -
JMW18_RS26035 () 71779..72570 + 792 WP_001325019.1 putative ribonucleotide transport ATP-binding protein mkl VF
JMW18_RS26040 () 72572..73510 + 939 WP_000449980.1 MCE family protein -
JMW18_RS26045 () 73510..74151 + 642 WP_000948259.1 membrane integrity-associated transporter subunit PqiC -
JMW18_RS26050 () 74259..75227 + 969 WP_000654805.1 IS5 family transposase IS903B Transposase
JMW18_RS26055 () 75727..77751 - 2025 WP_023312628.1 hypothetical protein -
JMW18_RS26060 () 77741..78727 - 987 WP_032192119.1 putative glycosyltransferase YkoT VF
JMW18_RS26065 () 78724..79110 - 387 WP_032192118.1 GtrA family protein -
JMW18_RS26070 () 79273..80205 - 933 WP_201519576.1 IS5 family transposase IS903B Transposase
JMW18_RS26075 () 80435..80650 - 216 Protein_85 IS5 family transposase ISKpn26 Transposase
JMW18_RS26080 () 80856..81494 + 639 Protein_86 transposase -
JMW18_RS26085 () 81764..82573 - 810 WP_000183578.1 polysaccharide pyruvyl transferase family protein -
JMW18_RS26090 () 82671..84893 + 2223 WP_020804634.1 glycosyltransferase -
JMW18_RS26095 () 85052..85749 + 698 Protein_89 IS1 family transposase IS1X4 Transposase
JMW18_RS26100 () 85906..86931 + 1026 WP_001101446.1 IS110 family transposase ISAve1 Transposase
JMW18_RS26105 () 87226..88194 + 969 WP_074194748.1 IS5 family transposase IS903B Transposase
JMW18_RS26110 () 89418..90275 - 858 WP_032249431.1 incFII family plasmid replication initiator RepA -
JMW18_RS26115 () 90268..90345 - 78 WP_020804505.1 RepA leader peptide Tap -
JMW18_RS26120 () 90561..90839 - 279 WP_004099069.1 replication regulatory protein RepA -
JMW18_RS26125 () 91160..91639 - 480 WP_064762441.1 Cardiolipin synthase B VF
JMW18_RS26130 () 92007..92704 - 698 Protein_96 IS1 family transposase ISKpn14 Transposase
JMW18_RS26135 () 92944..94986 - 2043 WP_020805034.1 DUF262 domain-containing HNH endonuclease family protein -
JMW18_RS26140 () 94979..96430 - 1452 WP_000443938.1 DUF262 domain-containing protein -
JMW18_RS26145 () 96455..96763 - 309 Protein_99 IS3 family transposase ISLad1 Transposase
JMW18_RS26150 () 96780..97019 - 240 Protein_100 IS110 family transposase -
JMW18_RS26155 () 97018..97203 - 186 Protein_101 IS1 family transposase -
JMW18_RS26160 () 97290..98045 - 756 WP_009310009.1 M48 family metallopeptidase -
JMW18_RS26165 () 98042..101326 - 3285 WP_013214044.1 type I restriction endonuclease subunit R -
JMW18_RS26170 () 101379..102062 - 684 WP_020803820.1 YecA family protein -
JMW18_RS26175 () 102059..103252 - 1194 WP_072271181.1 restriction endonuclease subunit S -
JMW18_RS26180 () 103299..104822 - 1524 WP_013214042.1 type I restriction-modification system subunit M -
JMW18_RS26185 () 105126..105823 - 698 Protein_107 IS1 family transposase -
JMW18_RS26190 () 105956..106549 - 594 WP_004152380.1 fertility inhibition protein FinO -
JMW18_RS26195 () 106621..107346 - 726 WP_013023834.1 type-F conjugative transfer system pilin acetylase TraX -
JMW18_RS26200 () 107392..112653 - 5262 WP_201519574.1 Multifunctional conjugation protein TraI Relaxase
JMW18_RS26205 () 112653..114965 - 2313 Protein_111 type IV conjugative transfer system coupling protein TraD -
JMW18_RS26210 () 115092..115781 - 690 WP_014343485.1 hypothetical protein -
JMW18_RS26215 () 115974..116591 - 618 WP_015065642.1 hypothetical protein -
JMW18_RS26220 () 116557..116703 - 147 WP_004197893.1 hypothetical protein -
JMW18_RS26225 () 117111..117644 - 534 WP_004197891.1 hypothetical protein -
JMW18_RS26230 () 117655..120498 - 2844 WP_020805032.1 conjugal transfer mating pair stabilization protein TraG -
JMW18_RS26235 () 120498..121877 - 1380 WP_179134156.1 conjugal transfer protein TraH -
JMW18_RS26240 () 121855..122298 - 444 WP_025712708.1 F-type conjugal transfer protein TrbF -
JMW18_RS26245 () 122344..122901 - 558 WP_004152678.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
JMW18_RS26250 () 122873..123112 - 240 WP_004144400.1 type-F conjugative transfer system pilin chaperone TraQ -
JMW18_RS26255 () 123123..123875 - 753 WP_004152677.1 type-F conjugative transfer system pilin assembly protein TraF -
JMW18_RS26260 () 123896..124222 - 327 WP_004144402.1 hypothetical protein -
JMW18_RS26265 () 124235..124483 - 249 WP_004152675.1 hypothetical protein -
JMW18_RS26270 () 124461..124715 - 255 WP_020804203.1 conjugal transfer protein TrbE -
JMW18_RS26275 () 124747..126702 - 1956 WP_025712707.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
JMW18_RS26280 () 126761..127399 - 639 WP_022644933.1 type-F conjugative transfer system pilin assembly protein TrbC -
JMW18_RS26285 () 127412..128404 - 993 WP_025712706.1 conjugal transfer pilus assembly protein TraU -
JMW18_RS26290 () 128415..129041 - 627 WP_025712705.1 type-F conjugative transfer system protein TraW -
JMW18_RS26295 () 129041..129430 - 390 WP_013214025.1 type-F conjugative transfer system protein TrbI -
JMW18_RS26300 () 129430..132069 - 2640 WP_025712704.1 type IV secretion system protein TraC -
JMW18_RS26305 () 132141..132539 - 399 WP_161283539.1 hypothetical protein -
JMW18_RS26310 () 132547..132846 - 300 WP_020805013.1 hypothetical protein -
JMW18_RS26315 () 132889..133293 - 405 WP_004197817.1 hypothetical protein -
JMW18_RS26320 () 133360..133671 - 312 WP_025712701.1 hypothetical protein -
JMW18_RS26325 () 133672..133890 - 219 WP_004195468.1 hypothetical protein -
JMW18_RS26330 () 134233..134412 - 180 WP_020805158.1 hypothetical protein -
JMW18_RS26335 () 134786..135370 - 585 WP_020277945.1 type IV conjugative transfer system lipoprotein TraV -
JMW18_RS26340 () 135444..136868 - 1425 WP_015065626.1 conjugal transfer protein TraB -
JMW18_RS26345 () 136868..137608 - 741 WP_048235042.1 type-F conjugative transfer system secretin TraK -
JMW18_RS26350 () 137595..138161 - 567 WP_004152602.1 type IV conjugative transfer system protein TraE -
JMW18_RS26355 () 138181..138486 - 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
JMW18_RS26360 () 138500..138868 - 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
JMW18_RS26365 () 138936..139136 - 201 WP_046664192.1 TraY domain-containing protein -
JMW18_RS26375 () 140721..141155 - 435 Protein_145 hypothetical protein -
JMW18_RS26380 () 141385..141777 - 393 WP_004194114.1 relaxosome protein TraM -
JMW18_RS26385 () 142209..142694 + 486 WP_001568108.1 hypothetical protein VF
JMW18_RS26390 () 142727..143056 - 330 WP_011977736.1 hypothetical protein -
JMW18_RS26395 () 143089..143910 - 822 WP_023316395.1 DUF945 domain-containing protein -
JMW18_RS26400 () 144832..146121 - 1290 WP_004574636.1 ISL3 family transposase ISPst9 Transposase
JMW18_RS26405 () 146143..146655 - 513 WP_004863699.1 Lipoprotein signal peptidase VF
JMW18_RS26410 () 146659..147555 - 897 WP_004574643.1 cation diffusion facilitator family transporter -
JMW18_RS26415 () 147651..148058 + 408 WP_004364961.1 Cd(II)/Pb(II)-responsive transcriptional regulator -
JMW18_RS26420 () 148145..148531 - 387 Protein_154 helix-turn-helix domain-containing protein -
JMW18_RS26425 () 148532..148810 - 279 WP_004152721.1 helix-turn-helix domain-containing protein -
JMW18_RS26430 () 148800..149120 - 321 WP_004152720.1 type II toxin-antitoxin system RelE/ParE family toxin -
JMW18_RS26435 () 149201..149425 - 225 WP_014343499.1 hypothetical protein -
JMW18_RS26440 () 149436..149648 - 213 WP_019706020.1 hypothetical protein -
JMW18_RS26445 () 149709..150065 - 357 WP_019706019.1 hypothetical protein -
JMW18_RS26450 () 150906..151223 - 318 WP_015065519.1 hypothetical protein -
JMW18_RS26455 () 151238..151588 - 351 WP_032425551.1 hypothetical protein -
JMW18_RS26460 () 151585..151857 - 273 WP_032425552.1 hypothetical protein -
JMW18_RS26465 () 152713..153825 - 1113 WP_001300563.1 IS4 family transposase IS421 Transposase
JMW18_RS26470 () 153904..154062 - 159 WP_014343509.1 type I toxin-antitoxin system Hok family toxin -
JMW18_RS26475 () 154134..155168 + 1035 Protein_165 IS481 family transposase ISKpn28 Transposase
JMW18_RS26480 () 155219..155506 - 288 WP_000323025.1 type II toxin-antitoxin system mRNA interferase RelE Toxin Detail
JMW18_RS26485 () 155506..155745 - 240 WP_004196370.1 type II toxin-antitoxin system antitoxin RelB Antitoxin Detail
JMW18_RS26490 () 155996..156361 + 366 WP_009651956.1 hypothetical protein -
JMW18_RS26495 () 156405..157142 + 738 WP_008460272.1 HupE/UreJ family protein -
JMW18_RS26500 () 157156..157845 + 690 WP_004196322.1 hypothetical protein -
JMW18_RS26505 () 157876..159252 - 1377 Protein_171 chromate efflux transporter -
JMW18_RS26510 () 159209..160186 - 978 WP_004196334.1 chromate resistance protein -
JMW18_RS26515 () 160216..160408 + 193 Protein_173 MFS transporter -
JMW18_RS26520 () 160533..160904 + 372 WP_004196359.1 hypothetical protein -
JMW18_RS26525 () 160967..161887 + 921 WP_004196315.1 hypothetical protein -
JMW18_RS26530 () 161941..162699 + 759 WP_004196325.1 hypothetical protein -
JMW18_RS26535 () 162933..164231 + 1299 WP_004196314.1 nickel resistance membrane nickel efflux protein NirA -
JMW18_RS26540 () 164337..164606 + 270 WP_004196355.1 nickel-sensing transcriptional repressor NcrB -
JMW18_RS26545 () 164619..165749 + 1131 WP_004196366.1 Ni(II)/Co(II) efflux transporter permease subunit NcrC -
JMW18_RS26550 () 165911..166333 + 423 WP_032072095.1 nickel resistance OB fold protein NcrY -
JMW18_RS26555 () 166589..167929 - 1341 WP_004196353.1 ISNCY family transposase ISCARN112 Transposase
JMW18_RS26560 () 168078..169151 + 1074 WP_117093126.1 IS481 family transposase ISKpn28 Transposase
JMW18_RS26565 () 169483..171765 - 2283 WP_162859354.1 S8 family peptidase -
JMW18_RS26570 () 171971..173011 - 1041 WP_022644891.1 ATP-binding protein -
JMW18_RS26575 () 173181..173474 - 294 Protein_185 IS3 family transposase ISKpn8 Transposase
JMW18_RS26580 () 173491..174573 - 1083 WP_020803817.1 IS110 family transposase ISEc21 Transposase
JMW18_RS26585 () 174778..175470 - 693 WP_116280963.1 IS3 family transposase ISKpn8 Transposase
JMW18_RS26590 () 175425..175934 - 510 WP_009310022.1 IS3 family transposase ISKpn8 Transposase
JMW18_RS26595 () 176123..176449 - 327 WP_015632484.1 hypothetical protein -
JMW18_RS26600 () 176446..177174 - 729 WP_022644893.1 plasmid SOS inhibition protein A -
JMW18_RS26605 () 177171..177602 - 432 WP_015632482.1 conjugation system SOS inhibitor PsiB -
JMW18_RS26610 () 177647..179647 - 2001 WP_022644894.1 ParB/RepB/Spo0J family partition protein -
JMW18_RS26615 () 179716..179964 - 249 WP_022644895.1 DUF905 domain-containing protein -
JMW18_RS26620 () 180013..180555 - 543 WP_022644896.1 single-stranded DNA-binding protein -
JMW18_RS26625 () 181230..181550 - 321 WP_022644897.1 hypothetical protein -
JMW18_RS26630 () 181586..181840 - 255 WP_025404029.1 DNA polymerase III subunit theta -
JMW18_RS26635 () 182034..182225 - 192 WP_022644899.1 hypothetical protein -
JMW18_RS26640 () 182268..182774 - 507 WP_048293767.1 antirestriction protein ArdA -
JMW18_RS26645 () 182817..183245 - 429 WP_004152356.1 antirestriction protein -
JMW18_RS26650 () 183926..184693 - 768 WP_001568044.1 hypothetical protein -
JMW18_RS26655 () 184747..185166 - 420 WP_001568043.1 DUF1380 domain-containing protein -
JMW18_RS26660 () 185176..185397 - 222 WP_001568042.1 hypothetical protein -
JMW18_RS26665 () 185397..186098 - 702 WP_001568041.1 DNA methylase -
JMW18_RS26670 () 186535..186765 - 231 WP_001568040.1 hypothetical protein -
JMW18_RS26675 () 186827..187498 - 672 WP_040213126.1 plasmid partitioning/stability family protein -
JMW18_RS26680 () 187501..188472 - 972 WP_001568038.1 hypothetical protein -
JMW18_RS26685 () 188721..190208 - 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
JMW18_RS26690 () 190611..191036 + 426 WP_009309980.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
JMW18_RS26695 () 191036..192307 + 1272 WP_004206782.1 Y-family DNA polymerase -
JMW18_RS26700 () 192386..192637 + 252 WP_004206783.1 plasmid stabilization protein -
JMW18_RS26705 () 192691..192996 + 306 WP_201519575.1 hypothetical protein -
JMW18_RS26710 () 194279..195250 - 972 WP_009309982.1 ParB/RepB/Spo0J family plasmid partition protein -
JMW18_RS26715 () 195250..196416 - 1167 WP_000523812.1 hypothetical protein VF

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance