MGE detailed information
MGE type: Conjugative plasmid MGE length: 134299 bp
Accession: NZ_CP124416 Location: 1..134299 Organism: Escherichia coli strain AVS0223 Replicon: plasmid pAVS0223-A
Accession: NZ_CP124416 Location: 1..134299 Organism: Escherichia coli strain AVS0223 Replicon: plasmid pAVS0223-A
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QJP60_RS24155 (1) | 1..978 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| QJP60_RS24160 (1263) | 1263..2003 | - | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| QJP60_RS24165 (2124) | 2124..2312 | - | 189 | WP_001309252.1 | hypothetical protein | - |
| QJP60_RS24170 (2679) | 2679..3848 | + | 1170 | WP_001072358.1 | hypothetical protein | - |
| QJP60_RS24175 (4074) | 4074..4249 | - | 176 | Protein_4 | IS3 family transposase | - |
| QJP60_RS24180 (4695) | 4695..4967 | - | 273 | WP_001322642.1 | Major pilu subunit operon regulatory protein PapB | VF |
| QJP60_RS24185 (5504) | 5504..5928 | - | 425 | Protein_6 | IS3 family transposase IS2 | Transposase |
| QJP60_RS24190 (6210) | 6210..8180 | + | 1971 | WP_001298664.1 | Hemin receptor | VF |
| QJP60_RS24195 (8187) | 8187..8978 | + | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| QJP60_RS24200 (9041) | 9041..9649 | - | 609 | Protein_9 | IS66 family transposase ISEc22 | Transposase |
| QJP60_RS24205 (9717) | 9717..10498 | - | 782 | Protein_10 | IS21 family transposase IS100 | Transposase |
| QJP60_RS24210 (10495) | 10495..11516 | - | 1022 | Protein_11 | IS21 family transposase IS100kyp | Transposase |
| QJP60_RS24215 (11601) | 11601..12545 | - | 945 | Protein_12 | IS66 family transposase ISEc8 | Transposase |
| QJP60_RS24220 (12594) | 12594..12941 | - | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| QJP60_RS24225 (12938) | 12938..13342 | - | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| QJP60_RS24230 (13422) | 13422..13760 | - | 339 | Protein_15 | IS3 family transposase IS629 | Transposase |
| QJP60_RS24235 (13844) | 13844..15352 | - | 1509 | WP_001189113.1 | group II intron reverse transcriptase/maturase | - |
| QJP60_RS24240 (16025) | 16025..16764 | - | 740 | Protein_17 | IS3 family transposase IS629 | Transposase |
| QJP60_RS24245 (16790) | 16790..17095 | + | 306 | Protein_18 | IS91 family transposase ISSbo1 | Transposase |
| QJP60_RS24250 (17618) | 17618..18793 | - | 1176 | WP_001020413.1 | putative protein YncE | VF |
| QJP60_RS24255 (18862) | 18862..21123 | - | 2262 | WP_001100763.1 | TonB-dependent receptor | - |
| QJP60_RS24260 (21292) | 21292..22068 | - | 777 | WP_000981091.1 | energy transducer TonB | - |
| QJP60_RS24265 (22076) | 22076..22951 | - | 876 | WP_001224623.1 | ChaN family lipoprotein | - |
| QJP60_RS24270 (23283) | 23283..23680 | - | 398 | Protein_23 | primase alpha helix C-terminal domain-containing protein | - |
| QJP60_RS24275 (23740) | 23740..24444 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| QJP60_RS24280 (24526) | 24526..24696 | + | 171 | Protein_25 | DsbA family protein | - |
| QJP60_RS24285 (24686) | 24686..25192 | + | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| QJP60_RS24290 (25429) | 25429..26190 | + | 762 | WP_001225378.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| QJP60_RS24295 (26537) | 26537..28423 | + | 1887 | WP_000118029.1 | FTR1 family protein | - |
| QJP60_RS24300 (28464) | 28464..28991 | + | 528 | WP_000178050.1 | iron transporter | - |
| QJP60_RS24305 (29095) | 29095..30474 | + | 1380 | WP_000119836.1 | Fe-S-containing protein | - |
| QJP60_RS24310 (30477) | 30477..31760 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| QJP60_RS24315 (31750) | 31750..32880 | + | 1131 | WP_000729218.1 | ABC transporter permease | - |
| QJP60_RS24320 (32885) | 32885..33580 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| QJP60_RS24325 (33567) | 33567..34052 | + | 486 | WP_001267176.1 | TlpA disulfide reductase family protein | - |
| QJP60_RS24330 (34077) | 34077..34562 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| QJP60_RS24335 (34684) | 34684..35317 | + | 634 | Protein_36 | histidine-type phosphatase | - |
| QJP60_RS24340 (35467) | 35467..35640 | - | 174 | Protein_37 | IS5 family transposase ISKpn26 | Transposase |
| QJP60_RS24345 (35641) | 35641..35954 | - | 314 | Protein_38 | hypothetical protein | - |
| QJP60_RS24350 (36462) | 36462..36587 | - | 126 | WP_283187932.1 | hypothetical protein | - |
| QJP60_RS24355 (36625) | 36625..37363 | - | 739 | Protein_40 | IS3 family transposase | - |
| QJP60_RS24360 (37465) | 37465..37725 | + | 261 | WP_000371882.1 | hypothetical protein | - |
| QJP60_RS24365 (37722) | 37722..38231 | + | 510 | WP_000194542.1 | hypothetical protein | - |
| QJP60_RS24370 (38251) | 38251..38598 | - | 348 | WP_000142452.1 | DUF6404 family protein | - |
| QJP60_RS24375 (38727) | 38727..39062 | + | 336 | WP_001080732.1 | colicin E1 family microcin immunity protein | - |
| QJP60_RS24380 (40514) | 40514..40794 | + | 281 | Protein_45 | replication initiation protein | - |
| QJP60_RS24385 (40847) | 40847..41550 | - | 704 | Protein_46 | IS6 family transposase IS15DII | Transposase |
| QJP60_RS24390 (41609) | 41609..42358 | - | 750 | Protein_47 | IS91 family transposase ISAzo26 | Transposase |
| QJP60_RS24395 (42516) | 42516..42989 | + | 474 | WP_001389366.1 | Dihydrofolate reductase type 1 | ARG |
| QJP60_RS24400 (43120) | 43120..43908 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| QJP60_RS24405 (44114) | 44114..44461 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| QJP60_RS24410 (44455) | 44455..45294 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| QJP60_RS24415 (45422) | 45422..45625 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| QJP60_RS24420 (45781) | 45781..46986 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| QJP60_RS24425 (46997) | 46997..47302 | + | 306 | WP_000130000.1 | Transcriptional regulator | Relaxase |
| QJP60_RS24430 (47346) | 47346..47411 | + | 66 | Protein_55 | EAL domain-containing protein | - |
| QJP60_RS24435 (47529) | 47529..48293 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| QJP60_RS24440 (48786) | 48786..49370 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| QJP60_RS24445 (49370) | 49370..50608 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| QJP60_RS24450 (50605) | 50605..51510 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| QJP60_RS24455 (51632) | 51632..52336 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| QJP60_RS24460 (52397) | 52397..52573 | + | 177 | Protein_61 | replication protein C, IncQ-type | - |
| QJP60_RS24465 (52881) | 52881..53696 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| QJP60_RS24470 (53757) | 53757..54560 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| QJP60_RS24475 (54560) | 54560..55396 | + | 837 | WP_000480972.1 | hypothetical protein | ARG |
| QJP60_RS24480 (55450) | 55450..55686 | + | 237 | WP_042005022.1 | hypothetical protein | - |
| QJP60_RS24485 (55718) | 55718..56344 | - | 627 | WP_031606906.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| QJP60_RS24490 (56450) | 56450..57649 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| QJP60_RS24495 (57681) | 57681..58013 | - | 333 | Protein_68 | EamA family transporter | - |
| QJP60_RS24500 (58066) | 58066..58770 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| QJP60_RS24505 (58830) | 58830..59192 | - | 363 | Protein_70 | IS5 family transposase IS903B | Transposase |
| QJP60_RS24510 (59227) | 59227..60102 | - | 876 | WP_032277257.1 | Beta-lactamase CTX-M-97 | ARG |
| QJP60_RS24515 (60416) | 60416..61095 | + | 680 | Protein_72 | IS6 family transposase IS15DI | Transposase |
| QJP60_RS24520 (61181) | 61181..61726 | + | 546 | Protein_73 | Tn3 family transposase TnpA_Tn3 | Transposase |
| QJP60_RS24525 (61762) | 61762..62176 | - | 415 | Protein_74 | IS1-like element IS1B family transposase | - |
| QJP60_RS24530 (62425) | 62425..62826 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| QJP60_RS24535 (62759) | 62759..63016 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| QJP60_RS24540 (63109) | 63109..63762 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| QJP60_RS24545 (64702) | 64702..65559 | - | 858 | WP_001617855.1 | incFII family plasmid replication initiator RepA | - |
| QJP60_RS24550 (65552) | 65552..65626 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| QJP60_RS24555 (65863) | 65863..66117 | - | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| QJP60_RS24560 (66414) | 66414..66548 | - | 135 | WP_023144756.1 | Hok/Gef family protein | Toxin Detail |
| - (66593) | 66593..66653 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - (66593) | 66593..66653 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - (66593) | 66593..66653 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - (66593) | 66593..66653 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| QJP60_RS24565 (66620) | 66620..66906 | - | 287 | Protein_82 | DUF2726 domain-containing protein | - |
| QJP60_RS24570 (66984) | 66984..68597 | - | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| QJP60_RS24575 (68628) | 68628..68978 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| QJP60_RS24580 (68975) | 68975..69400 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| QJP60_RS24585 (69959) | 69959..70171 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| QJP60_RS24590 (70302) | 70302..70862 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| QJP60_RS24595 (70917) | 70917..71663 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| QJP60_RS24600 (71683) | 71683..76953 | - | 5271 | WP_001617867.1 | Multifunctional conjugation protein TraI | Relaxase |
| QJP60_RS24605 (76953) | 76953..79115 | - | 2163 | WP_023144755.1 | type IV conjugative transfer system coupling protein TraD | - |
| QJP60_RS24610 (79112) | 79112..79891 | - | 780 | WP_000199914.1 | hypothetical protein | - |
| QJP60_RS24615 (80094) | 80094..80825 | - | 732 | WP_000850429.1 | conjugal transfer complement resistance protein TraT | - |
| QJP60_RS24620 (80857) | 80857..81354 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| QJP60_RS24625 (81373) | 81373..84192 | - | 2820 | WP_001007062.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| QJP60_RS24630 (84189) | 84189..85562 | - | 1374 | WP_000944328.1 | conjugal transfer pilus assembly protein TraH | - |
| QJP60_RS24635 (85549) | 85549..85941 | - | 393 | WP_000659962.1 | F-type conjugal transfer protein TrbF | - |
| QJP60_RS24640 (85922) | 85922..86269 | - | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| QJP60_RS24645 (86199) | 86199..86744 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| QJP60_RS24650 (86731) | 86731..87015 | - | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| QJP60_RS24655 (87142) | 87142..87462 | - | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| QJP60_RS24660 (87510) | 87510..88207 | - | 698 | Protein_101 | IS1 family transposase IS1X2 | Transposase |
| QJP60_RS24665 (88281) | 88281..88592 | - | 312 | WP_000012107.1 | type IV conjugative transfer system protein TraL | - |
| QJP60_RS24670 (88597) | 88597..88959 | - | 363 | WP_000338606.1 | type IV conjugative transfer system pilin TraA | - |
| QJP60_RS24675 (88993) | 88993..89220 | - | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| QJP60_RS24680 (89308) | 89308..89985 | - | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| QJP60_RS24685 (90119) | 90119..90502 | - | 384 | WP_001151566.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| QJP60_RS24690 (90845) | 90845..91435 | + | 591 | WP_001376243.1 | hypothetical protein | VF |
| QJP60_RS24695 (91732) | 91732..92553 | - | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| QJP60_RS24700 (92672) | 92672..92959 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| QJP60_RS24705 (92984) | 92984..93190 | - | 207 | WP_000275859.1 | hypothetical protein | - |
| QJP60_RS24710 (93260) | 93260..93433 | + | 174 | Protein_111 | hypothetical protein | - |
| QJP60_RS24715 (93431) | 93431..93661 | - | 231 | WP_001426396.1 | hypothetical protein | - |
| QJP60_RS24720 (93881) | 93881..94006 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| QJP60_RS24725 (93948) | 93948..94097 | - | 150 | Protein_114 | plasmid maintenance protein Mok | - |
| - (94083) | 94083..94123 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - (94083) | 94083..94123 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - (94083) | 94083..94123 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - (94083) | 94083..94123 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - (95567) | 95567..95753 | - | 187 | NuclAT_0 | - | - |
| - (95567) | 95567..95753 | - | 187 | NuclAT_0 | - | - |
| - (95567) | 95567..95753 | - | 187 | NuclAT_0 | - | - |
| - (95567) | 95567..95753 | - | 187 | NuclAT_0 | - | - |
| QJP60_RS24735 (95722) | 95722..96484 | - | 763 | Protein_116 | plasmid SOS inhibition protein A | - |
| QJP60_RS24740 (96481) | 96481..96915 | - | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| QJP60_RS24745 (96970) | 96970..98928 | - | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| QJP60_RS24750 (98994) | 98994..99227 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| QJP60_RS24755 (99290) | 99290..99829 | - | 540 | WP_000290841.1 | single-stranded DNA-binding protein | - |
| QJP60_RS24760 (99855) | 99855..100061 | - | 207 | WP_024189527.1 | hypothetical protein | - |
| QJP60_RS24765 (99974) | 99974..100309 | - | 336 | WP_013023876.1 | hypothetical protein | - |
| QJP60_RS24770 (100472) | 100472..100732 | - | 261 | WP_024623314.1 | hypothetical protein | - |
| QJP60_RS24775 (100758) | 100758..101321 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| QJP60_RS24780 (101369) | 101369..102730 | - | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| QJP60_RS24785 (102782) | 102782..103012 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| QJP60_RS24790 (104047) | 104047..104238 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| QJP60_RS24795 (104235) | 104235..104657 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| QJP60_RS24800 (104704) | 104704..105129 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| QJP60_RS24805 (105546) | 105546..106322 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| QJP60_RS24810 (106373) | 106373..106891 | - | 519 | WP_236922986.1 | DUF1380 family protein | - |
| QJP60_RS24815 (106821) | 106821..107042 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| QJP60_RS24820 (107043) | 107043..107726 | - | 684 | WP_000086185.1 | DNA methylase | - |
| QJP60_RS24825 (107803) | 107803..108114 | - | 312 | WP_032143366.1 | hypothetical protein | - |
| QJP60_RS24830 (108111) | 108111..109013 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| QJP60_RS24835 (109880) | 109880..110851 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| QJP60_RS24840 (110851) | 110851..112017 | - | 1167 | WP_000772446.1 | hypothetical protein | VF |
| QJP60_RS24845 (112605) | 112605..113360 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| QJP60_RS24850 (114134) | 114134..114940 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| QJP60_RS24855 (114941) | 114941..115246 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| QJP60_RS24860 (115248) | 115248..115466 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| QJP60_RS24865 (116174) | 116174..117169 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| QJP60_RS24870 (117173) | 117173..118105 | + | 933 | WP_000991832.1 | S-4TM family putative pore-forming effector | - |
| QJP60_RS24880 (119153) | 119153..122269 | - | 3117 | WP_001553854.1 | HsdR family type I site-specific deoxyribonuclease | - |
| QJP60_RS24885 (122391) | 122391..123674 | - | 1284 | WP_001617890.1 | restriction endonuclease subunit S | - |
| QJP60_RS24890 (123671) | 123671..125227 | - | 1557 | WP_001617892.1 | type I restriction-modification system subunit M | - |
| QJP60_RS24895 (125410) | 125410..125631 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| QJP60_RS24900 (125631) | 125631..126011 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| QJP60_RS24905 (126016) | 126016..126195 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| QJP60_RS24910 (126223) | 126223..126501 | + | 279 | Protein_151 | pdcB | - |
| QJP60_RS24915 (126506) | 126506..126919 | + | 414 | Protein_152 | IS3 family transposase ISLad1 | Transposase |
| QJP60_RS24920 (126937) | 126937..127311 | - | 375 | WP_283187931.1 | type I restriction endonuclease | - |
| QJP60_RS24925 (127410) | 127410..128391 | - | 982 | Protein_154 | IS5 family transposase IS5D | Transposase |
| QJP60_RS24930 (128635) | 128635..130038 | + | 1404 | WP_001373486.1 | S-methylmethionine permease | - |
| QJP60_RS24935 (130025) | 130025..130957 | + | 933 | WP_000081352.1 | homocysteine S-methyltransferase | - |
| QJP60_RS24940 (131066) | 131066..131395 | - | 330 | Protein_157 | TOBE domain-containing protein | - |
| QJP60_RS24950 (132256) | 132256..132414 | + | 159 | WP_228955855.1 | abortive infection family protein | - |
| QJP60_RS24955 (132573) | 132573..133544 | - | 972 | Protein_160 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|