MGE detailed information
MGE type: Conjugative plasmid MGE length: 138734 bp
Accession: NZ_CP123262 Location: 1..138734 Organism: Escherichia coli strain YZLc4-1 Replicon: plasmid pYZLc4-1_138k
Accession: NZ_CP123262 Location: 1..138734 Organism: Escherichia coli strain YZLc4-1 Replicon: plasmid pYZLc4-1_138k
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| N4697_RS24270 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| N4697_RS24275 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| N4697_RS24280 (2124) | 2124..2306 | - | 183 | WP_170884432.1 | serine/threonine protein kinase | - |
| N4697_RS24285 (2373) | 2373..2663 | - | 291 | Protein_3 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| N4697_RS24290 (2706) | 2706..2917 | - | 212 | Protein_4 | type II toxin-antitoxin system ParD family antitoxin | - |
| N4697_RS24295 (3449) | 3449..4372 | + | 924 | WP_232379287.1 | hypothetical protein | - |
| N4697_RS24300 (4805) | 4805..6022 | - | 1218 | Protein_6 | IS3 family transposase IS2 | Transposase |
| N4697_RS24305 (6292) | 6292..6540 | + | 249 | WP_270658969.1 | FaeA/PapI family transcriptional regulator | - |
| N4697_RS24310 (6663) | 6663..6913 | + | 251 | Protein_8 | polysaccharide deacetylase family protein | - |
| N4697_RS24315 (7008) | 7008..7346 | + | 339 | WP_228395588.1 | group II intron maturase-specific domain-containing protein | - |
| N4697_RS24320 (7414) | 7414..7588 | + | 175 | Protein_10 | transposase domain-containing protein | - |
| N4697_RS24325 (7782) | 7782..8795 | - | 1014 | WP_053285703.1 | sulfite reductase subunit C | - |
| N4697_RS24330 (8806) | 8806..9624 | - | 819 | WP_012565200.1 | anaerobic sulfite reductase subunit AsrB | - |
| N4697_RS24335 (9628) | 9628..10671 | - | 1044 | WP_000279209.1 | anaerobic sulfite reductase subunit AsrA | - |
| N4697_RS24340 (11109) | 11109..11648 | + | 540 | WP_247194354.1 | type 1 fimbrial protein | - |
| N4697_RS24345 (11713) | 11713..12423 | + | 711 | WP_160513604.1 | Chaperone protein FocC | VF |
| N4697_RS24350 (12431) | 12431..12988 | + | 558 | WP_160393474.1 | type 1 fimbrial protein | - |
| N4697_RS24355 (13020) | 13020..13583 | + | 564 | WP_126633351.1 | fimbrial protein | - |
| N4697_RS24360 (13586) | 13586..14287 | + | 702 | WP_089551190.1 | molecular chaperone | - |
| N4697_RS24365 (14232) | 14232..15023 | + | 792 | WP_106141718.1 | molecular chaperone | - |
| N4697_RS24370 (15027) | 15027..17639 | + | 2613 | WP_053285699.1 | Outer membrane usher protein FimD | VF |
| N4697_RS24375 (17659) | 17659..18888 | + | 1230 | WP_247194356.1 | hypothetical protein | - |
| N4697_RS24380 (19221) | 19221..19970 | + | 750 | WP_106141716.1 | EAL domain-containing protein | - |
| N4697_RS24385 (20015) | 20015..20689 | - | 675 | WP_232379284.1 | HTH-type transcriptional activator RhaR | VF |
| N4697_RS24390 (21130) | 21130..22014 | + | 885 | WP_000942222.1 | helix-turn-helix domain-containing protein | - |
| N4697_RS24395 (22151) | 22151..22297 | - | 147 | WP_162822579.1 | hypothetical protein | - |
| N4697_RS24400 (22297) | 22297..22538 | - | 242 | Protein_26 | hypothetical protein | - |
| N4697_RS24405 (22598) | 22598..23040 | + | 443 | Protein_27 | IS3 family transposase ISEc25 | Transposase |
| N4697_RS24410 (23225) | 23225..23455 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| N4697_RS24415 (23452) | 23452..23868 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| N4697_RS24420 (24221) | 24221..24307 | - | 87 | Protein_30 | IS66 family transposase IS679 | Transposase |
| N4697_RS24425 (24307) | 24307..24954 | - | 648 | WP_180391910.1 | IS66 family transposase IS679 | Transposase |
| N4697_RS24430 (25027) | 25027..25188 | + | 162 | WP_001384894.1 | hypothetical protein | - |
| N4697_RS24435 (25560) | 25560..26417 | - | 858 | WP_202374666.1 | Diacetyl reductase [(S)-acetoin forming] | VF |
| N4697_RS24440 (26519) | 26519..26737 | + | 219 | WP_001292878.1 | hypothetical protein | - |
| N4697_RS24445 (26780) | 26780..27877 | + | 1098 | WP_221686783.1 | choloylglycine hydrolase family protein | - |
| N4697_RS24450 (27960) | 27960..29612 | + | 1653 | WP_180391914.1 | NAD-dependent malic enzyme | - |
| N4697_RS24455 (29678) | 29678..31138 | + | 1461 | WP_001425198.1 | anion permease | - |
| N4697_RS24460 (31414) | 31414..31783 | - | 370 | Protein_38 | resolvase | - |
| N4697_RS24465 (31807) | 31807..32209 | - | 403 | Protein_39 | IS66 family transposase ISEc43 | Transposase |
| N4697_RS24475 (33632) | 33632..34378 | - | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| N4697_RS24480 (34393) | 34393..35934 | - | 1542 | WP_001298859.1 | IS21 family transposase ISEc12 | Transposase |
| N4697_RS24485 (36445) | 36445..36846 | + | 402 | WP_149026544.1 | hypothetical protein | - |
| N4697_RS24490 (37009) | 37009..37443 | - | 435 | WP_281438051.1 | IS3 family transposase ISCARN101 | Transposase |
| N4697_RS24495 (37509) | 37509..37649 | + | 141 | Protein_45 | integrase core domain-containing protein | - |
| N4697_RS24500 (37866) | 37866..39542 | - | 1677 | WP_284166961.1 | hypothetical protein | - |
| N4697_RS24505 (40032) | 40032..40308 | - | 277 | Protein_47 | hypothetical protein | - |
| N4697_RS24510 (40448) | 40448..41212 | - | 765 | WP_053285766.1 | hypothetical protein | VF |
| N4697_RS24515 (41243) | 41243..42040 | - | 798 | WP_053285765.1 | hypothetical protein | VF |
| N4697_RS24520 (42232) | 42232..43008 | - | 777 | WP_162822580.1 | hypothetical protein | - |
| N4697_RS24525 (43230) | 43230..44012 | - | 783 | WP_221686785.1 | fimbrial protein | - |
| N4697_RS24530 (44202) | 44202..44693 | - | 492 | WP_053285762.1 | hypothetical protein | VF |
| N4697_RS24535 (44729) | 44729..45505 | - | 777 | WP_001697781.1 | Chaperone protein FaeE | VF |
| N4697_RS24540 (45498) | 45498..47936 | - | 2439 | WP_241555759.1 | Outer membrane usher protein YraJ | VF |
| N4697_RS24545 (47948) | 47948..48493 | - | 546 | WP_000708866.1 | hypothetical protein | VF |
| N4697_RS24550 (48493) | 48493..48816 | - | 324 | WP_000431569.1 | hypothetical protein | VF |
| N4697_RS24555 (49286) | 49286..49477 | + | 192 | WP_032174713.1 | P fimbrial regulatory protein KS71A | VF |
| N4697_RS24560 (49632) | 49632..49874 | + | 243 | WP_262935004.1 | hypothetical protein | - |
| N4697_RS24565 (49851) | 49851..52817 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| N4697_RS24570 (52821) | 52821..53381 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| N4697_RS24575 (53557) | 53557..53907 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| N4697_RS24580 (54110) | 54110..55119 | - | 1010 | Protein_62 | class 1 integron integrase IntI1 | - |
| N4697_RS24585 (55277) | 55277..55744 | + | 468 | Protein_63 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| N4697_RS24590 (55877) | 55877..56666 | + | 790 | Protein_64 | Streptomycin 3''-adenylyltransferase | ARG |
| N4697_RS24595 (56868) | 56868..57572 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| N4697_RS24600 (57625) | 57625..58380 | + | 756 | Protein_66 | IS110 family transposase IS5075 | Transposase |
| N4697_RS24605 (58652) | 58652..58738 | - | 87 | Protein_67 | Arm DNA-binding domain-containing protein | - |
| N4697_RS24610 (59068) | 59068..59878 | + | 811 | Protein_68 | Dihydropteroate synthase | ARG |
| N4697_RS24615 (59965) | 59965..60183 | + | 219 | Protein_69 | phosphoglucosamine mutase | - |
| N4697_RS24620 (60439) | 60439..61932 | - | 1494 | WP_001120888.1 | IS91 family transposase ISVsa3 | Transposase |
| N4697_RS24625 (62143) | 62143..62367 | - | 225 | WP_000743213.1 | hypothetical protein | - |
| N4697_RS24630 (62364) | 62364..63101 | - | 738 | WP_001446887.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| N4697_RS24635 (63587) | 63587..63727 | - | 141 | WP_001044210.1 | hypothetical protein | - |
| N4697_RS24640 (63733) | 63733..64437 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| N4697_RS24645 (64462) | 64462..64752 | + | 291 | WP_033557184.1 | hypothetical protein | - |
| N4697_RS24650 (65126) | 65126..65212 | + | 87 | Protein_76 | hypothetical protein | - |
| N4697_RS24655 (65271) | 65271..65552 | - | 282 | WP_000780224.1 | helix-turn-helix transcriptional regulator | - |
| N4697_RS24660 (65533) | 65533..65862 | - | 330 | Protein_78 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| N4697_RS24665 (66797) | 66797..67654 | - | 858 | WP_053285823.1 | incFII family plasmid replication initiator RepA | - |
| N4697_RS24670 (67647) | 67647..67721 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| N4697_RS24675 (67959) | 67959..68219 | - | 261 | WP_000078108.1 | replication regulatory protein RepA | - |
| N4697_RS24680 (68928) | 68928..69527 | - | 600 | WP_000256072.1 | PIN domain-containing protein | - |
| N4697_RS24685 (69911) | 69911..70123 | - | 213 | WP_032145766.1 | ANR family transcriptional regulator | - |
| N4697_RS24690 (70262) | 70262..70819 | - | 558 | WP_053285822.1 | fertility inhibition protein FinO | - |
| N4697_RS24695 (70874) | 70874..71620 | - | 747 | WP_053285821.1 | conjugal transfer pilus acetylase TraX | - |
| N4697_RS24700 (71640) | 71640..76910 | - | 5271 | WP_053285820.1 | Multifunctional conjugation protein TraI | Relaxase |
| N4697_RS24705 (76910) | 76910..79099 | - | 2190 | WP_247194431.1 | type IV conjugative transfer system coupling protein TraD | - |
| N4697_RS24710 (79381) | 79381..79992 | - | 612 | WP_000908442.1 | hypothetical protein | - |
| N4697_RS24715 (80064) | 80064..80795 | - | 732 | WP_053285825.1 | conjugal transfer complement resistance protein TraT | - |
| N4697_RS24720 (80827) | 80827..81324 | - | 498 | WP_053285818.1 | entry exclusion protein | - |
| N4697_RS24725 (81343) | 81343..84162 | - | 2820 | WP_180391890.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| N4697_RS24730 (84159) | 84159..85532 | - | 1374 | WP_000944325.1 | conjugal transfer pilus assembly protein TraH | - |
| N4697_RS24735 (85519) | 85519..85911 | - | 393 | WP_053285816.1 | F-type conjugal transfer protein TrbF | - |
| N4697_RS24740 (85898) | 85898..86239 | - | 342 | WP_071528036.1 | P-type conjugative transfer protein TrbJ | - |
| N4697_RS24745 (86169) | 86169..86714 | - | 546 | WP_000052614.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| N4697_RS24750 (86701) | 86701..86985 | - | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| N4697_RS24755 (87104) | 87104..87451 | - | 348 | WP_021534925.1 | conjugal transfer protein TrbA | - |
| N4697_RS24760 (87467) | 87467..88210 | - | 744 | WP_001030376.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| N4697_RS24765 (88203) | 88203..88460 | - | 258 | WP_053285815.1 | conjugal transfer protein TrbE | - |
| N4697_RS24770 (88487) | 88487..90295 | - | 1809 | WP_053285814.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| N4697_RS24775 (90292) | 90292..90930 | - | 639 | WP_001104086.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| N4697_RS24780 (90958) | 90958..91410 | - | 453 | WP_027663276.1 | hypothetical protein | - |
| N4697_RS24785 (91403) | 91403..91717 | - | 315 | WP_027663275.1 | hypothetical protein | - |
| N4697_RS24790 (91728) | 91728..92192 | - | 465 | WP_221686793.1 | ATP-binding protein | - |
| N4697_RS24795 (92218) | 92218..93210 | - | 993 | WP_000830839.1 | conjugal transfer pilus assembly protein TraU | - |
| N4697_RS24800 (93207) | 93207..93839 | - | 633 | WP_221686794.1 | type-F conjugative transfer system protein TraW | - |
| N4697_RS24805 (93836) | 93836..94222 | - | 387 | WP_000214096.1 | type-F conjugative transfer system protein TrbI | - |
| N4697_RS24810 (94219) | 94219..96846 | - | 2628 | WP_042064810.1 | type IV secretion system protein TraC | - |
| N4697_RS24815 (97006) | 97006..97227 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| N4697_RS24820 (97362) | 97362..97877 | - | 516 | WP_053285811.1 | type IV conjugative transfer system lipoprotein TraV | - |
| N4697_RS24825 (97874) | 97874..98125 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| N4697_RS24830 (98137) | 98137..98334 | - | 198 | WP_247194433.1 | conjugal transfer protein TrbD | - |
| N4697_RS24835 (98321) | 98321..98908 | - | 588 | WP_053285809.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| N4697_RS24840 (98898) | 98898..100325 | - | 1428 | WP_053285808.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| N4697_RS24845 (100325) | 100325..101053 | - | 729 | WP_001230788.1 | type-F conjugative transfer system secretin TraK | - |
| N4697_RS24850 (101040) | 101040..101606 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| N4697_RS24855 (101628) | 101628..101939 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| N4697_RS24860 (101944) | 101944..102306 | - | 363 | WP_000340279.1 | type IV conjugative transfer system pilin TraA | - |
| N4697_RS24865 (102349) | 102349..102564 | - | 216 | WP_000086380.1 | conjugal transfer relaxosome protein TraY | - |
| N4697_RS24870 (102700) | 102700..103347 | - | 648 | WP_053285807.1 | conjugal transfer transcriptional regulator TraJ | - |
| N4697_RS24875 (103538) | 103538..103921 | - | 384 | WP_001151533.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| N4697_RS24880 (104199) | 104199..104846 | + | 648 | WP_122987040.1 | hypothetical protein | VF |
| N4697_RS24885 (105142) | 105142..105963 | - | 822 | WP_001234475.1 | DUF932 domain-containing protein | - |
| N4697_RS24890 (106082) | 106082..106369 | - | 288 | WP_000107542.1 | hypothetical protein | - |
| N4697_RS24895 (106686) | 106686..106965 | + | 280 | Protein_125 | hypothetical protein | - |
| N4697_RS24900 (107266) | 107266..107391 | - | 126 | WP_096937776.1 | type I toxin-antitoxin system Hok family toxin | - |
| N4697_RS24905 (107333) | 107333..107482 | - | 150 | Protein_127 | DUF5431 family protein | - |
| - (107489) | 107489..107687 | - | 199 | NuclAT_0 | - | - |
| - (107489) | 107489..107687 | - | 199 | NuclAT_0 | - | - |
| - (107489) | 107489..107687 | - | 199 | NuclAT_0 | - | - |
| - (107489) | 107489..107687 | - | 199 | NuclAT_0 | - | - |
| N4697_RS24910 (107656) | 107656..108418 | - | 763 | Protein_128 | plasmid SOS inhibition protein A | - |
| N4697_RS24915 (108415) | 108415..108849 | - | 435 | WP_000845928.1 | conjugation system SOS inhibitor PsiB | - |
| N4697_RS24920 (108904) | 108904..110862 | - | 1959 | WP_221686813.1 | ParB/RepB/Spo0J family partition protein | - |
| N4697_RS24925 (110928) | 110928..111161 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| N4697_RS24930 (111218) | 111218..111757 | - | 540 | WP_000290799.1 | single-stranded DNA-binding protein | - |
| N4697_RS24935 (112075) | 112075..112584 | + | 510 | WP_071532140.1 | hypothetical protein | - |
| N4697_RS24940 (112554) | 112554..112745 | - | 192 | WP_001027495.1 | hypothetical protein | - |
| N4697_RS24945 (112742) | 112742..113164 | - | 423 | WP_000271685.1 | DUF1380 family protein | - |
| N4697_RS24950 (113211) | 113211..113636 | - | 426 | WP_001198920.1 | antirestriction protein | - |
| N4697_RS24955 (114049) | 114049..114825 | - | 777 | WP_001005032.1 | hypothetical protein | - |
| N4697_RS24960 (114871) | 114871..115425 | - | 555 | Protein_138 | DUF1380 family protein | - |
| N4697_RS24965 (115319) | 115319..115540 | - | 222 | WP_053285711.1 | hypothetical protein | - |
| N4697_RS24970 (115541) | 115541..116224 | - | 684 | WP_000085939.1 | DNA methylase | - |
| N4697_RS24975 (116301) | 116301..116606 | - | 306 | WP_010891292.1 | hypothetical protein | - |
| N4697_RS24980 (116610) | 116610..117511 | - | 902 | Protein_142 | DUF1281 domain-containing protein | - |
| N4697_RS24985 (118421) | 118421..119392 | - | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| N4697_RS24990 (119392) | 119392..120558 | - | 1167 | WP_000772446.1 | hypothetical protein | VF |
| N4697_RS24995 (121146) | 121146..121901 | - | 756 | WP_221686810.1 | replication initiation protein RepE | - |
| N4697_RS25000 (122623) | 122623..123429 | - | 807 | WP_053285710.1 | site-specific integrase | - |
| N4697_RS25005 (123430) | 123430..123735 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| N4697_RS25010 (123737) | 123737..123955 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| N4697_RS25015 (124547) | 124547..125035 | + | 489 | WP_011254646.1 | hypothetical protein | - |
| N4697_RS25020 (125069) | 125069..126202 | - | 1134 | WP_000545987.1 | DUF3800 domain-containing protein | - |
| N4697_RS25025 (126369) | 126369..127142 | - | 774 | WP_000905949.1 | hypothetical protein | - |
| N4697_RS25030 (127155) | 127155..127655 | - | 501 | WP_000528932.1 | HEPN family nuclease | - |
| N4697_RS25035 (127920) | 127920..128150 | + | 231 | WP_001261278.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| N4697_RS25040 (128147) | 128147..128563 | + | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| N4697_RS25045 (128608) | 128608..132402 | - | 3795 | WP_221686811.1 | pcar | - |
| N4697_RS25050 (132783) | 132783..133013 | + | 231 | WP_001261286.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| N4697_RS25055 (133010) | 133010..133426 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| N4697_RS25060 (133501) | 133501..135066 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| N4697_RS25065 (135051) | 135051..136073 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| N4697_RS25075 (137079) | 137079..137499 | - | 421 | Protein_161 | protein ImpB | - |
| N4697_RS25080 (137560) | 137560..137664 | - | 105 | Protein_162 | AAA family ATPase | - |
| N4697_RS25085 (137666) | 137666..137989 | - | 324 | Protein_163 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|