MGE detailed information
MGE type: Conjugative plasmid MGE length: 96218 bp
Accession: NZ_CP121221 Location: 1..96218 Organism: Shigella flexneri 2a strain Sflex 21-42 Replicon: plasmid unnamed4
Accession: NZ_CP121221 Location: 1..96218 Organism: Shigella flexneri 2a strain Sflex 21-42 Replicon: plasmid unnamed4
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| P5F89_RS00085 () | 352..555 | + | 204 | WP_001336517.1 | hypothetical protein | - |
| P5F89_RS00090 () | 1308..1769 | + | 462 | WP_000760080.1 | thermonuclease family protein | - |
| P5F89_RS00095 () | 1872..2255 | + | 384 | WP_001109264.1 | hypothetical protein | - |
| P5F89_RS00100 () | 2408..2845 | + | 438 | WP_000872609.1 | hypothetical protein | - |
| - () | 2940..2996 | - | 57 | NuclAT_1 | - | Antitoxin Detail |
| - () | 2940..2996 | - | 57 | NuclAT_1 | - | Antitoxin Detail |
| - () | 2940..2996 | - | 57 | NuclAT_1 | - | Antitoxin Detail |
| - () | 2940..2996 | - | 57 | NuclAT_1 | - | Antitoxin Detail |
| P5F89_RS00105 () | 3044..3193 | + | 150 | WP_001336447.1 | Hok/Gef family protein | Toxin Detail |
| P5F89_RS00110 () | 3478..3735 | + | 258 | WP_000084404.1 | replication regulatory protein RepA | - |
| P5F89_RS00115 () | 3969..4043 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| P5F89_RS00120 () | 4036..4893 | + | 858 | WP_001537577.1 | incFII family plasmid replication initiator RepA | - |
| P5F89_RS00125 () | 5594..5734 | + | 141 | WP_021503378.1 | hypothetical protein | - |
| P5F89_RS00130 () | 5807..6076 | + | 270 | WP_000079939.1 | type II toxin-antitoxin system antitoxin YacA | - |
| P5F89_RS00135 () | 6076..6186 | + | 111 | Protein_11 | type II toxin-antitoxin system toxin YacB | - |
| P5F89_RS00140 () | 6285..7208 | + | 924 | WP_001415483.1 | hypothetical protein | - |
| P5F89_RS00145 () | 7650..8030 | + | 381 | WP_001696636.1 | HTH domain-containing protein | - |
| P5F89_RS00150 () | 8142..8546 | + | 405 | Protein_14 | IS91 family transposase ISPps1 | Transposase |
| P5F89_RS00155 () | 8653..9489 | - | 837 | WP_000480972.1 | hypothetical protein | ARG |
| P5F89_RS00160 () | 9489..10292 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| P5F89_RS00165 () | 10353..11168 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| P5F89_RS00170 () | 11505..11708 | + | 204 | WP_000131876.1 | hypothetical protein | - |
| P5F89_RS00175 () | 11699..11920 | + | 222 | WP_001251694.1 | hypothetical protein | - |
| P5F89_RS00180 () | 12155..12484 | - | 330 | WP_001415369.1 | hypothetical protein | - |
| P5F89_RS00185 () | 12671..12853 | - | 183 | Protein_21 | class A beta-lactamase | - |
| P5F89_RS00190 () | 12907..13611 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P5F89_RS00195 () | 13902..14585 | + | 684 | Protein_23 | class A beta-lactamase | - |
| P5F89_RS00200 () | 14650..15354 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P5F89_RS00205 () | 15497..18394 | - | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| P5F89_RS00210 () | 18489..19095 | + | 607 | Protein_26 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| P5F89_RS00215 () | 19119..19868 | - | 750 | Protein_27 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| P5F89_RS00220 () | 19872..20264 | + | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| P5F89_RS00225 () | 20402..21286 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| P5F89_RS00230 () | 21318..22517 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| P5F89_RS00235 () | 22623..23273 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| P5F89_RS00240 () | 23305..23547 | - | 243 | WP_032140899.1 | hypothetical protein | - |
| P5F89_RS00245 () | 23589..25103 | - | 1515 | Protein_33 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| P5F89_RS00250 () | 25169..25873 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P5F89_RS00255 () | 25927..26367 | - | 441 | Protein_35 | CatB-related O-acetyltransferase | - |
| P5F89_RS00260 () | 26505..27335 | - | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| P5F89_RS00265 () | 27466..28020 | - | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| P5F89_RS00270 () | 28164..28868 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P5F89_RS00275 () | 28986..29387 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| P5F89_RS00280 () | 29320..29577 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| P5F89_RS00285 () | 29670..30323 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| P5F89_RS00290 () | 30422..32314 | - | 1893 | Protein_42 | Tn3 family transposase TnpA_Tn3 | Transposase |
| P5F89_RS00295 () | 32370..33074 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P5F89_RS00300 () | 33404..33676 | + | 273 | WP_001322642.1 | adhesin biosynthesis transcription regulatory family protein | - |
| P5F89_RS00305 () | 34122..34297 | + | 176 | Protein_45 | IS3 family transposase | - |
| P5F89_RS00310 () | 34523..35692 | - | 1170 | WP_001072359.1 | hypothetical protein | - |
| P5F89_RS00315 () | 36059..36247 | + | 189 | WP_001332784.1 | hypothetical protein | - |
| P5F89_RS00320 () | 36368..37108 | + | 741 | WP_001066947.1 | IS91 family transposase ISMno23 | Transposase |
| P5F89_RS00325 () | 37351..38328 | - | 978 | WP_001309253.1 | RepB family plasmid replication initiator protein | - |
| P5F89_RS00330 () | 38972..39383 | - | 412 | Protein_50 | DDE-type integrase/transposase/recombinase | - |
| P5F89_RS00335 () | 39385..39672 | - | 288 | WP_001270422.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| P5F89_RS00340 () | 39669..39920 | - | 252 | WP_001132895.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| P5F89_RS00345 () | 40093..40224 | - | 132 | WP_001309255.1 | hypothetical protein | - |
| P5F89_RS00350 () | 40678..41883 | + | 1206 | WP_000817635.1 | Plasmid partition protein A | VF |
| P5F89_RS00355 () | 41880..42842 | + | 963 | WP_000756328.1 | ParB family protein | - |
| P5F89_RS00360 () | 43076..43852 | + | 777 | Protein_56 | transposase DNA-binding-containing protein | - |
| P5F89_RS00365 () | 43981..44064 | - | 84 | Protein_57 | DUF4113 domain-containing protein | - |
| P5F89_RS00370 () | 44066..44594 | + | 529 | Protein_58 | DUF1281 domain-containing protein | - |
| P5F89_RS00375 () | 44591..44902 | + | 312 | WP_001309256.1 | hypothetical protein | - |
| P5F89_RS00380 () | 44978..45661 | + | 684 | WP_000086171.1 | DNA methylase | - |
| P5F89_RS00385 () | 45662..45883 | + | 222 | WP_001104892.1 | hypothetical protein | - |
| P5F89_RS00390 () | 45813..46331 | + | 519 | WP_224955273.1 | DUF1380 family protein | - |
| P5F89_RS00395 () | 46376..47146 | + | 771 | WP_001044390.1 | hypothetical protein | - |
| P5F89_RS00400 () | 47560..47985 | + | 426 | WP_001198924.1 | antirestriction protein | - |
| P5F89_RS00405 () | 47955..48446 | + | 492 | WP_289228578.1 | hypothetical protein | - |
| P5F89_RS00410 () | 48446..48637 | + | 192 | WP_001027049.1 | hypothetical protein | - |
| P5F89_RS00415 () | 48616..49087 | - | 472 | Protein_67 | hypothetical protein | - |
| P5F89_RS00420 () | 49367..49507 | + | 141 | WP_021561179.1 | hypothetical protein | - |
| P5F89_RS00425 () | 49605..49835 | + | 231 | WP_001537563.1 | hypothetical protein | - |
| P5F89_RS00430 () | 49887..51248 | + | 1362 | WP_000170705.1 | DUF3560 domain-containing protein | - |
| P5F89_RS00435 () | 51294..51857 | + | 564 | WP_001309257.1 | class I SAM-dependent methyltransferase | - |
| P5F89_RS00440 () | 51943..52380 | - | 438 | Protein_72 | hypothetical protein | - |
| P5F89_RS00445 () | 52682..53209 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| P5F89_RS00450 () | 53267..53500 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| P5F89_RS00455 () | 53561..55525 | + | 1965 | WP_001537566.1 | ParB/RepB/Spo0J family partition protein | - |
| P5F89_RS00460 () | 55594..56028 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| P5F89_RS00465 () | 56025..56744 | + | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| - () | 56756..56980 | + | 225 | NuclAT_0 | - | - |
| - () | 56756..56980 | + | 225 | NuclAT_0 | - | - |
| - () | 56756..56980 | + | 225 | NuclAT_0 | - | - |
| - () | 56756..56980 | + | 225 | NuclAT_0 | - | - |
| P5F89_RS00470 () | 56765..56944 | - | 180 | WP_001309233.1 | hypothetical protein | - |
| - | 56913..56978 | - | 66 | - | - | Antitoxin Detail |
| P5F89_RS00475 () | 56966..57115 | + | 150 | Protein_79 | plasmid maintenance protein Mok | - |
| P5F89_RS00480 () | 57057..57182 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| P5F89_RS00485 () | 57483..57779 | - | 297 | Protein_81 | hypothetical protein | - |
| P5F89_RS00490 () | 58079..58375 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| P5F89_RS00495 () | 58485..59306 | + | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| P5F89_RS00500 () | 59602..60111 | - | 510 | WP_000759173.1 | hypothetical protein | VF |
| P5F89_RS00505 () | 60525..60908 | + | 384 | WP_001151538.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| P5F89_RS00510 () | 61095..61784 | + | 690 | WP_000283387.1 | conjugal transfer transcriptional regulator TraJ | - |
| P5F89_RS00515 () | 61877..62278 | + | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| P5F89_RS00520 () | 62311..62670 | + | 360 | WP_001099001.1 | type IV conjugative transfer system pilin TraA | - |
| P5F89_RS00525 () | 62685..62996 | + | 312 | WP_000012100.1 | type IV conjugative transfer system protein TraL | - |
| P5F89_RS00530 () | 63018..63584 | + | 567 | WP_000399780.1 | type IV conjugative transfer system protein TraE | - |
| P5F89_RS00535 () | 63571..64299 | + | 729 | WP_001230767.1 | type-F conjugative transfer system secretin TraK | - |
| P5F89_RS00540 () | 64299..65750 | + | 1452 | WP_000146663.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| P5F89_RS00545 () | 65740..66306 | + | 567 | WP_000896598.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| P5F89_RS00550 () | 66293..66610 | + | 318 | WP_001057297.1 | conjugal transfer protein TrbD | - |
| P5F89_RS00555 () | 66610..67125 | + | 516 | WP_000809872.1 | type IV conjugative transfer system lipoprotein TraV | - |
| P5F89_RS00560 () | 67260..67481 | + | 222 | WP_001278695.1 | conjugal transfer protein TraR | - |
| P5F89_RS00565 () | 67474..67887 | + | 414 | WP_000549574.1 | hypothetical protein | - |
| P5F89_RS00570 () | 67880..68353 | + | 474 | WP_000549566.1 | hypothetical protein | - |
| P5F89_RS00575 () | 68433..68651 | + | 219 | WP_000556746.1 | hypothetical protein | - |
| P5F89_RS00580 () | 69018..71647 | + | 2630 | Protein_100 | type IV secretion system protein TraC | - |
| P5F89_RS00585 () | 71644..72029 | + | 386 | Protein_101 | type-F conjugative transfer system protein TrbI | - |
| P5F89_RS00590 () | 72026..72658 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| P5F89_RS00595 () | 72655..73647 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| P5F89_RS00600 () | 73674..73982 | + | 309 | WP_000412445.1 | hypothetical protein | - |
| P5F89_RS00605 () | 74045..74563 | + | 519 | WP_000009088.1 | hypothetical protein | - |
| P5F89_RS00610 () | 74590..75228 | + | 639 | WP_000087539.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| P5F89_RS00615 () | 75225..75596 | + | 372 | WP_000174465.1 | hypothetical protein | - |
| P5F89_RS00620 () | 75621..76043 | + | 423 | WP_001229309.1 | HNH endonuclease signature motif containing protein | - |
| P5F89_RS00625 () | 76040..77890 | + | 1851 | WP_000826177.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| P5F89_RS00630 () | 77917..78174 | + | 258 | WP_000864310.1 | conjugal transfer protein TrbE | - |
| P5F89_RS00635 () | 78167..78910 | + | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| P5F89_RS00640 () | 78924..79265 | + | 342 | WP_000556795.1 | conjugal transfer protein TrbA | - |
| P5F89_RS00645 () | 79662..79946 | + | 285 | WP_000624194.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| P5F89_RS00650 () | 79933..80478 | + | 546 | WP_000059830.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| P5F89_RS00655 () | 80468..80782 | + | 315 | WP_001336805.1 | P-type conjugative transfer protein TrbJ | - |
| P5F89_RS00660 () | 80736..81128 | + | 393 | WP_000138369.1 | F-type conjugal transfer protein TrbF | - |
| P5F89_RS00665 () | 81115..82488 | + | 1374 | WP_000944331.1 | conjugal transfer pilus assembly protein TraH | - |
| P5F89_RS00670 () | 82485..85304 | + | 2820 | WP_001537571.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| P5F89_RS00675 () | 85323..85820 | + | 498 | WP_000605862.1 | entry exclusion protein | - |
| P5F89_RS00680 () | 85852..86583 | + | 732 | WP_000850422.1 | conjugal transfer complement resistance protein TraT | - |
| P5F89_RS00685 () | 86786..87523 | + | 738 | WP_000199901.1 | hypothetical protein | - |
| P5F89_RS00690 () | 87574..89790 | + | 2217 | WP_001545324.1 | type IV conjugative transfer system coupling protein TraD | - |
| P5F89_RS00695 () | 89790..95060 | + | 5271 | WP_001545323.1 | Multifunctional conjugation protein TraI | Relaxase |
| P5F89_RS00700 () | 95080..95826 | + | 747 | WP_000205709.1 | conjugal transfer pilus acetylase TraX | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|