NZ_CP1164811..138420

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 138420 bp
Accession: NZ_CP116481        Location: 1..138420         Organism: Escherichia coli strain GTEN_24       Replicon: plasmid unnamed1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E5Q65_RS23280 (1) 1..978 + 978 WP_000361610.1 RepB family plasmid replication initiator protein -
E5Q65_RS23285 (1263) 1263..2003 - 741 WP_001066942.1 tyrosine-type recombinase/integrase -
E5Q65_RS23290 (2124) 2124..2306 - 183 WP_042065278.1 hypothetical protein -
E5Q65_RS23295 (2373) 2373..2662 - 290 Protein_3 type II toxin-antitoxin system RelE/ParE family toxin -
E5Q65_RS23300 (2649) 2649..2917 - 269 Protein_4 type II toxin-antitoxin system ParD family antitoxin -
E5Q65_RS23305 (3449) 3449..4618 + 1170 WP_023909118.1 hypothetical protein -
E5Q65_RS23310 (4651) 4651..4779 + 129 Protein_6 IS481 family transposase -
E5Q65_RS23315 (4814) 4814..5002 - 189 Protein_7 hypothetical protein -
E5Q65_RS23320 (5050) 5050..5747 + 698 WP_095033700.1 IS1 family transposase IS1R Transposase
E5Q65_RS23325 (5763) 5763..5882 + 120 Protein_9 transcriptional regulator -
E5Q65_RS23330 (5860) 5860..6483 - 624 WP_000088605.1 Tetracycline repressor protein class B from transposon Tn10 VF
E5Q65_RS23335 (6565) 6565..7770 + 1206 WP_001089068.1 Tetracycline resistance protein, class B ARG
E5Q65_RS23340 (7883) 7883..8128 - 246 Protein_12 transposase -
E5Q65_RS23350 (9265) 9265..10245 - 981 WP_031311978.1 IS5 family transposase ISKpn26 Transposase
E5Q65_RS23355 (10319) 10319..10978 + 660 WP_000412211.1 Chloramphenicol acetyltransferase ARG
E5Q65_RS23360 (11179) 11179..11556 - 378 WP_000656305.1 GNAT family N-acetyltransferase -
E5Q65_RS23365 (11623) 11623..14589 - 2967 WP_023909098.1 Tn3 family transposase TnpA_TnAs3 Transposase
E5Q65_RS23370 (14592) 14592..15002 - 411 Protein_18 Tn3 family transposase TnpR_TnAs3 Transposase
E5Q65_RS23375 (15068) 15068..15772 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
E5Q65_RS23380 (15823) 15823..15897 - 75 Protein_20 PadR family transcriptional regulator -
E5Q65_RS23385 (15908) 15908..17113 - 1206 WP_000184001.1 chromate efflux transporter -
E5Q65_RS23390 (17269) 17269..17472 - 204 WP_000376616.1 hypothetical protein -
E5Q65_RS23395 (17600) 17600..18439 - 840 WP_000259031.1 Dihydropteroate synthase ARG
E5Q65_RS23400 (18433) 18433..18780 - 348 WP_000679427.1 Multidrug transporter EmrE ARG
E5Q65_RS23405 (18897) 18897..19735 - 839 Protein_25 Streptomycin 3''-adenylyltransferase ARG
E5Q65_RS23410 (19741) 19741..20031 - 291 WP_001336345.1 DUF1010 domain-containing protein -
E5Q65_RS23415 (20143) 20143..20640 - 498 WP_001083725.1 IS1595 family transposase ISSsu9 ARG
E5Q65_RS23420 (20785) 20785..21084 + 300 Protein_28 60 kDa chaperonin VF
E5Q65_RS23425 (21085) 21085..21438 + 354 Protein_29 60 kDa chaperonin VF
E5Q65_RS23430 (21713) 21713..23197 + 1485 WP_022742855.1 IS91 family transposase -
E5Q65_RS23435 (23436) 23436..23822 + 387 Protein_31 mechanosensitive ion channel -
E5Q65_RS23440 (23850) 23850..25385 - 1536 WP_064760451.1 fluoroquinolone efflux MFS transporter QepA4 ARG
E5Q65_RS23445 (25780) 25780..26793 + 1014 WP_000845039.1 IS91 family transposase ISAzo26 Transposase
E5Q65_RS23450 (26996) 26996..27346 + 351 WP_000454193.1 DUF3330 domain-containing protein -
E5Q65_RS23455 (27472) 27472..27627 + 156 Protein_35 Tn3 family transposase TnpR_TnAs3 Transposase
E5Q65_RS23460 (27680) 27680..28384 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
E5Q65_RS23465 (28447) 28447..28935 - 489 Protein_37 IS6 family transposase IS15 Transposase
E5Q65_RS23470 (29000) 29000..29239 + 240 Protein_38 Transcriptional regulator Relaxase
E5Q65_RS23475 (29283) 29283..29348 + 66 Protein_39 EAL domain-containing protein -
E5Q65_RS23480 (29466) 29466..30230 + 765 WP_001389365.1 IS6-like element IS6100 family transposase -
E5Q65_RS23485 (30723) 30723..31307 - 585 WP_001137892.1 macrolide-binding transcriptional repressor MphR(A) -
E5Q65_RS23490 (31307) 31307..32545 - 1239 WP_000004159.1 macrolide resistance MFS transporter Mrx(A) -
E5Q65_RS23495 (32542) 32542..33447 - 906 WP_000219391.1 hypothetical protein ARG
E5Q65_RS23500 (33569) 33569..34273 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
E5Q65_RS23505 (34408) 34408..34503 + 96 WP_013362819.1 23S rRNA methyltransferase attenuation leader peptide -
E5Q65_RS23510 (34629) 34629..35366 + 738 WP_013362818.1 rRNA adenine N-6-methyltransferase ARG
E5Q65_RS23515 (35996) 35996..36445 + 450 WP_013362817.1 hypothetical protein -
E5Q65_RS23520 (36406) 36406..36747 + 342 WP_023909256.1 60 kDa chaperonin VF
E5Q65_RS23525 (37022) 37022..38506 + 1485 WP_032152108.1 IS91 family transposase -
E5Q65_RS23530 (38829) 38829..39533 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
E5Q65_RS23535 (39598) 39598..39864 + 267 Protein_51 Tn3 family transposase TnpA_Tn3 Transposase
E5Q65_RS23540 (39941) 39941..40645 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
E5Q65_RS23545 (40711) 40711..41256 + 546 Protein_53 Tn3 family transposase TnpA_Tn3 Transposase
E5Q65_RS23550 (41292) 41292..41707 - 416 Protein_54 IS1-like element IS1B family transposase -
E5Q65_RS23555 (41956) 41956..42357 - 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
E5Q65_RS23560 (42290) 42290..42547 - 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
E5Q65_RS23565 (42640) 42640..43293 - 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
E5Q65_RS23570 (44232) 44232..45089 - 858 WP_000130646.1 incFII family plasmid replication initiator RepA -
E5Q65_RS23575 (45082) 45082..45156 - 75 WP_014966221.1 RepA leader peptide Tap -
E5Q65_RS23580 (45518) 45518..47059 + 1542 WP_002431311.1 IS21 family transposase ISEc12 Transposase
E5Q65_RS23585 (47074) 47074..47820 + 747 WP_001016257.1 IS21 family transposase ISEc12 Transposase
E5Q65_RS23590 (47980) 47980..48234 - 255 WP_000083850.1 replication regulatory protein RepA -
E5Q65_RS23595 (48531) 48531..48665 - 135 WP_023144756.1 Hok/Gef family protein Toxin Detail
- (48710) 48710..48770 + 61 NuclAT_2 - Antitoxin Detail
- (48710) 48710..48770 + 61 NuclAT_2 - Antitoxin Detail
- (48710) 48710..48770 + 61 NuclAT_2 - Antitoxin Detail
- (48710) 48710..48770 + 61 NuclAT_2 - Antitoxin Detail
E5Q65_RS23600 (48737) 48737..49023 - 287 Protein_64 DUF2726 domain-containing protein -
E5Q65_RS23605 (49536) 49536..49748 - 213 WP_013023861.1 hypothetical protein -
E5Q65_RS23610 (49879) 49879..50439 - 561 WP_000139341.1 fertility inhibition protein FinO -
E5Q65_RS23615 (50494) 50494..51240 - 747 WP_023909066.1 conjugal transfer pilus acetylase TraX -
E5Q65_RS23620 (51260) 51260..56530 - 5271 WP_001617867.1 Multifunctional conjugation protein TraI Relaxase
E5Q65_RS23625 (56530) 56530..58737 - 2208 WP_021547900.1 type IV conjugative transfer system coupling protein TraD -
E5Q65_RS23630 (58734) 58734..59513 - 780 WP_000199914.1 hypothetical protein -
E5Q65_RS23635 (59716) 59716..60447 - 732 WP_000850429.1 conjugal transfer complement resistance protein TraT -
E5Q65_RS23640 (60479) 60479..60976 - 498 WP_033876670.1 entry exclusion protein -
E5Q65_RS23645 (60995) 60995..63814 - 2820 WP_001007062.1 conjugal transfer mating-pair stabilization protein TraG -
E5Q65_RS23650 (63811) 63811..65184 - 1374 WP_000944328.1 conjugal transfer pilus assembly protein TraH -
E5Q65_RS23655 (65171) 65171..65563 - 393 WP_000659962.1 F-type conjugal transfer protein TrbF -
E5Q65_RS23660 (65544) 65544..65891 - 348 WP_071571857.1 P-type conjugative transfer protein TrbJ -
E5Q65_RS23665 (65821) 65821..66366 - 546 WP_000059829.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
E5Q65_RS23670 (66353) 66353..66637 - 285 WP_001617873.1 type-F conjugative transfer system pilin chaperone TraQ -
E5Q65_RS23675 (66764) 66764..67084 - 321 WP_001348757.1 conjugal transfer protein TrbA -
E5Q65_RS23685 (67885) 67885..68151 - 267 Protein_81 conjugal transfer protein TrbD -
E5Q65_RS23690 (68090) 68090..68656 - 567 WP_000896601.1 conjugal transfer pilus-stabilizing protein TraP -
E5Q65_RS23695 (68646) 68646..70097 - 1452 WP_000146687.1 F-type conjugal transfer pilus assembly protein TraB -
E5Q65_RS23700 (70097) 70097..70825 - 729 WP_001230808.1 type-F conjugative transfer system secretin TraK -
E5Q65_RS23705 (70812) 70812..71378 - 567 WP_000399791.1 type IV conjugative transfer system protein TraE -
E5Q65_RS23710 (71400) 71400..71711 - 312 WP_000012107.1 type IV conjugative transfer system protein TraL -
E5Q65_RS23715 (71716) 71716..72078 - 363 WP_000338606.1 type IV conjugative transfer system pilin TraA -
E5Q65_RS23720 (72112) 72112..72339 - 228 WP_001254388.1 conjugal transfer relaxosome protein TraY -
E5Q65_RS23725 (72427) 72427..73104 - 678 WP_001348626.1 PAS domain-containing protein -
E5Q65_RS23730 (73238) 73238..73621 - 384 WP_001151566.1 conjugal transfer relaxosome DNA-binding protein TraM -
E5Q65_RS23735 (73952) 73952..74554 + 603 WP_000243712.1 hypothetical protein VF
E5Q65_RS23740 (74851) 74851..75672 - 822 WP_001234469.1 DUF932 domain-containing protein -
E5Q65_RS23745 (75791) 75791..76078 - 288 WP_000107535.1 hypothetical protein -
E5Q65_RS23750 (76103) 76103..76309 - 207 WP_000275859.1 hypothetical protein -
E5Q65_RS23755 (76379) 76379..76552 + 174 Protein_95 hypothetical protein -
E5Q65_RS23760 (76550) 76550..76780 - 231 WP_001426396.1 hypothetical protein -
E5Q65_RS23765 (77000) 77000..77125 - 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
E5Q65_RS23770 (77067) 77067..77216 - 150 Protein_98 plasmid maintenance protein Mok -
- (77202) 77202..77240 - 39 NuclAT_1 - Antitoxin Detail
- (77202) 77202..77240 - 39 NuclAT_1 - Antitoxin Detail
- (77202) 77202..77240 - 39 NuclAT_1 - Antitoxin Detail
- (77202) 77202..77240 - 39 NuclAT_1 - Antitoxin Detail
- (78680) 78680..78782 - 103 NuclAT_0 - -
- (78680) 78680..78782 - 103 NuclAT_0 - -
- (78680) 78680..78782 - 103 NuclAT_0 - -
- (78680) 78680..78782 - 103 NuclAT_0 - -
E5Q65_RS23780 (78751) 78751..79513 - 763 Protein_100 plasmid SOS inhibition protein A -
E5Q65_RS23785 (79510) 79510..79944 - 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
E5Q65_RS23790 (80013) 80013..82036 - 2024 Protein_102 ParB/RepB/Spo0J family partition protein -
E5Q65_RS23795 (82097) 82097..82330 - 234 WP_000006003.1 DUF905 family protein -
E5Q65_RS23800 (82388) 82388..82873 - 486 WP_031311812.1 single-stranded DNA-binding protein -
E5Q65_RS23805 (83023) 83023..84924 - 1902 WP_000936285.1 group II intron reverse transcriptase/maturase -
E5Q65_RS23810 (85878) 85878..86333 + 456 Protein_106 hypothetical protein -
E5Q65_RS23815 (86419) 86419..86982 - 564 WP_001298559.1 class I SAM-dependent methyltransferase -
E5Q65_RS23820 (87029) 87029..88390 - 1362 WP_000170695.1 DUF3560 domain-containing protein -
E5Q65_RS23825 (88442) 88442..88672 - 231 WP_000218642.1 hypothetical protein -
E5Q65_RS23830 (89710) 89710..89901 - 192 WP_001027493.1 hypothetical protein -
E5Q65_RS23835 (89898) 89898..90320 - 423 WP_000271762.1 DUF1380 family protein -
E5Q65_RS23840 (90367) 90367..90792 - 426 WP_001198928.1 antirestriction protein -
E5Q65_RS23845 (91210) 91210..91986 - 777 WP_001383963.1 hypothetical protein -
E5Q65_RS23850 (92037) 92037..92471 - 435 WP_000274503.1 DUF1380 family protein -
E5Q65_RS23855 (92485) 92485..92706 - 222 WP_001104881.1 hypothetical protein -
E5Q65_RS23860 (92707) 92707..93390 - 684 WP_000086185.1 DNA methylase -
E5Q65_RS23865 (93467) 93467..93778 - 312 WP_011254640.1 hypothetical protein -
E5Q65_RS23870 (93775) 93775..94677 - 903 WP_001348615.1 DUF1281 domain-containing protein -
E5Q65_RS23875 (95544) 95544..96515 - 972 WP_000817036.1 ParB/RepB/Spo0J family plasmid partition protein -
E5Q65_RS23880 (96515) 96515..97681 - 1167 WP_000772446.1 hypothetical protein VF
E5Q65_RS23885 (98269) 98269..99024 - 756 WP_000852146.1 replication initiation protein RepE -
E5Q65_RS23890 (99798) 99798..100604 - 807 WP_000016982.1 site-specific integrase -
E5Q65_RS23895 (100605) 100605..100910 - 306 WP_001159868.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
E5Q65_RS23900 (100912) 100912..101130 - 219 WP_023909027.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
E5Q65_RS23905 (101764) 101764..101961 + 198 WP_000215657.1 hypothetical protein -
E5Q65_RS23910 (101958) 101958..102242 - 285 WP_000642771.1 hypothetical protein -
E5Q65_RS23915 (102262) 102262..103395 - 1134 WP_000545983.1 DUF3800 domain-containing protein -
E5Q65_RS23920 (103658) 103658..106777 - 3120 WP_023909028.1 hypothetical protein -
E5Q65_RS23925 (107084) 107084..107314 + 231 WP_001261287.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
E5Q65_RS23930 (107311) 107311..107727 + 417 WP_001044768.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
E5Q65_RS23935 (107889) 107889..108896 - 1008 Protein_131 AAA family ATPase -
E5Q65_RS23940 (108959) 108959..109663 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
E5Q65_RS23945 (109716) 109716..109940 + 225 Protein_133 IS6 family transposase IS26 Transposase
E5Q65_RS23950 (110126) 110126..111109 + 984 WP_113962661.1 IS481 family transposase ISKpn27 Transposase
E5Q65_RS23955 (111480) 111480..112955 + 1476 WP_000052512.1 ABC-F type ribosomal protection protein Msr(E) ARG
E5Q65_RS23960 (113011) 113011..113895 + 885 WP_000155092.1 hypothetical protein ARG
E5Q65_RS23965 (114034) 114034..114291 - 258 WP_159516864.1 hypothetical protein -
E5Q65_RS23970 (114395) 114395..115099 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
E5Q65_RS23975 (115154) 115154..115408 + 255 Protein_139 SDR family oxidoreductase -
E5Q65_RS23980 (115504) 115504..116148 - 645 WP_017900990.1 Pentapeptide repeat protein ARG
E5Q65_RS23985 (116231) 116231..117205 - 975 WP_004193248.1 Psp operon transcriptional activator VF
E5Q65_RS23990 (117376) 117376..118044 + 669 WP_003020532.1 phage shock protein PspA -
E5Q65_RS23995 (118099) 118099..118323 + 225 WP_004193245.1 envelope stress response membrane protein PspB -
E5Q65_RS24000 (118323) 118323..118682 + 360 WP_004193243.1 envelope stress response membrane protein PspC -
E5Q65_RS24005 (118691) 118691..118921 + 231 WP_004193241.1 phage shock protein PspD -
E5Q65_RS24010 (119110) 119110..119298 - 189 Protein_146 LacI family transcriptional regulator -
E5Q65_RS24015 (119256) 119256..120077 - 822 WP_013214003.1 hypothetical protein -
E5Q65_RS24020 (120272) 120272..121411 - 1140 WP_004236386.1 Beta-lactamase ARG
E5Q65_RS24025 (121522) 121522..122397 + 876 WP_004193231.1 LysR family transcriptional regulator AmpR -
E5Q65_RS24030 (122401) 122401..122766 - 366 WP_025999322.1 hydrogenase maturation nickel metallochaperone HypA -
E5Q65_RS24035 (122659) 122659..122994 + 336 WP_052238321.1 SMR family transporter -
E5Q65_RS24040 (122988) 122988..123827 + 840 WP_000259031.1 Dihydropteroate synthase ARG
E5Q65_RS24045 (123955) 123955..124455 + 501 WP_000376623.1 GNAT family N-acetyltransferase -
E5Q65_RS24050 (124531) 124531..125235 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
E5Q65_RS24055 (125126) 125126..126427 - 1302 WP_272056125.1 hypothetical protein -
E5Q65_RS24060 (126892) 126892..127887 + 996 WP_000246636.1 hypothetical protein -
E5Q65_RS24065 (127930) 127930..128823 + 894 WP_001553853.1 S-4TM family putative pore-forming effector -
E5Q65_RS24075 (129871) 129871..132987 - 3117 WP_031311986.1 HsdR family type I site-specific deoxyribonuclease -
E5Q65_RS24080 (133109) 133109..134380 - 1272 WP_023142242.1 restriction endonuclease subunit S -
E5Q65_RS24085 (134377) 134377..135933 - 1557 WP_001553856.1 type I restriction-modification system subunit M -
E5Q65_RS24090 (136116) 136116..136337 + 222 WP_001190712.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
E5Q65_RS24095 (136337) 136337..136717 + 381 WP_001216034.1 type II toxin-antitoxin system death-on-curing family toxin -
E5Q65_RS24100 (136722) 136722..136901 + 180 WP_001513661.1 hypothetical protein -
E5Q65_RS24105 (136929) 136929..137207 + 279 Protein_165 pdcB -
E5Q65_RS24110 (137212) 137212..137625 + 414 Protein_166 IS3 family transposase ISLad1 Transposase

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance