NZ_CP1161371..151807

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 151807 bp
Accession: NZ_CP116137        Location: 1..151807         Organism: Escherichia coli strain DETEC-P649       Replicon: plasmid pDETEC25


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PIB66_RS23800 (1301) 1301..2041 - 741 WP_016238487.1 tyrosine-type recombinase/integrase -
PIB66_RS23805 (2411) 2411..2700 - 290 Protein_2 type II toxin-antitoxin system RelE/ParE family toxin -
PIB66_RS23810 (2687) 2687..2955 - 269 Protein_3 type II toxin-antitoxin system ParD family antitoxin -
PIB66_RS23815 (3487) 3487..4656 + 1170 WP_001072355.1 hypothetical protein -
PIB66_RS23820 (4689) 4689..4817 + 129 Protein_5 IS481 family transposase -
PIB66_RS23825 (4942) 4942..5145 - 204 Protein_6 hypothetical protein -
PIB66_RS23830 (5251) 5251..5526 - 276 WP_000421272.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
PIB66_RS23835 (5526) 5526..5810 - 285 WP_001387467.1 ribbon-helix-helix domain-containing protein Antitoxin Detail
PIB66_RS23840 (6415) 6415..7167 + 753 WP_000562172.1 IclR family transcriptional regulator -
PIB66_RS23845 (7213) 7213..8178 - 966 WP_001022265.1 2-keto-3-deoxygluconate transporter -
PIB66_RS23850 (8211) 8211..8591 - 381 WP_000710783.1 Rid family detoxifying hydrolase -
PIB66_RS23855 (8616) 8616..9506 - 891 WP_001077068.1 dihydrodipicolinate synthase family protein -
PIB66_RS23860 (9739) 9739..9933 - 195 WP_000796505.1 hypothetical protein -
PIB66_RS23865 (9907) 9907..10347 + 441 Protein_14 zinc-binding dehydrogenase -
PIB66_RS23870 (10478) 10478..11356 + 879 WP_000338039.1 sugar ABC transporter permease -
PIB66_RS23875 (11346) 11346..12233 + 888 WP_001271561.1 carbohydrate ABC transporter permease -
PIB66_RS23880 (12244) 12244..13068 + 825 WP_000922702.1 phosphodiesterase -
PIB66_RS23885 (13074) 13074..14147 + 1074 WP_000950177.1 sn-glycerol-3-phosphate import ATP-binding protein UgpC VF
PIB66_RS23890 (14140) 14140..15450 + 1311 WP_000476108.1 ABC transporter substrate-binding protein -
PIB66_RS23895 (15509) 15509..15817 - 309 Protein_20 IS4 family transposase ISEc13 Transposase
PIB66_RS23900 (15894) 15894..16067 - 174 WP_000338295.1 Tn3 family transposase ISPsy39 Transposase
PIB66_RS23905 (16149) 16149..16629 - 481 Protein_22 IS3 family transposase IS629 Transposase
PIB66_RS23910 (16713) 16713..18221 - 1509 WP_001189123.1 group II intron reverse transcriptase/maturase -
PIB66_RS23915 (18894) 18894..19615 - 722 Protein_24 IS3 family transposase IS629 Transposase
PIB66_RS23920 (19640) 19640..20344 + 705 WP_001067834.1 IS6 family transposase IS26 Transposase
PIB66_RS23925 (20402) 20402..20932 - 531 Protein_26 histidine-type phosphatase -
PIB66_RS23930 (21054) 21054..21539 - 486 WP_000874189.1 hypothetical protein -
PIB66_RS23935 (21564) 21564..22049 - 486 WP_001267177.1 TlpA disulfide reductase family protein -
PIB66_RS23940 (22036) 22036..22731 - 696 WP_000117262.1 Lipoprotein-releasing system ATP-binding protein LolD VF
PIB66_RS23945 (22736) 22736..23866 - 1131 WP_000729220.1 ABC transporter permease -
PIB66_RS23950 (23856) 23856..25139 - 1284 WP_000964653.1 ABC transporter permease -
PIB66_RS23955 (25142) 25142..26521 - 1380 WP_000119836.1 Fe-S-containing protein -
PIB66_RS23960 (26625) 26625..27152 - 528 WP_000178050.1 iron transporter -
PIB66_RS23965 (27193) 27193..29079 - 1887 WP_000118029.1 FTR1 family protein -
PIB66_RS23970 (29426) 29426..30187 - 762 WP_001225378.1 Na(+)-translocating NADH-quinone reductase subunit C -
PIB66_RS23975 (30424) 30424..30930 - 507 WP_080177532.1 protein disulfide oxidoreductase -
PIB66_RS23980 (30920) 30920..31090 - 171 Protein_37 DsbA family protein -
PIB66_RS23985 (31228) 31228..31341 - 114 Protein_38 IS6 family transposase -
PIB66_RS23990 (31541) 31541..32238 + 698 WP_151884388.1 IS1 family transposase IS1X2 Transposase
PIB66_RS23995 (32256) 32256..33128 + 873 Protein_40 IS4 family transposase IS10R Transposase
PIB66_RS24000 (33138) 33138..33554 - 417 WP_000275180.1 Transposon Tn10 TetD protein VF
PIB66_RS24005 (33642) 33642..34235 + 594 WP_000428546.1 tetracyline resistance-associated transcriptional repressor TetC -
PIB66_RS24010 (34348) 34348..35553 - 1206 WP_001089068.1 Tetracycline resistance protein, class B ARG
PIB66_RS24015 (35635) 35635..36258 + 624 WP_000088605.1 Tetracycline repressor protein class B from transposon Tn10 VF
PIB66_RS24020 (36236) 36236..36922 - 687 WP_001284954.1 winged helix-turn-helix domain-containing protein -
PIB66_RS24025 (36930) 36930..37316 - 387 WP_000460651.1 hypothetical protein -
PIB66_RS24030 (37309) 37309..37572 - 264 WP_049802299.1 antibiotic biosynthesis monooxygenase -
PIB66_RS24040 (38322) 38322..39218 - 897 Protein_49 Tn3 family transposase TnpA_TnAs3 Transposase
PIB66_RS24045 (39221) 39221..39781 - 561 WP_000147567.1 Tn3 family transposase TnpR_TnAs3 Transposase
PIB66_RS24050 (39907) 39907..40257 - 351 WP_000454193.1 DUF3330 domain-containing protein -
PIB66_RS24055 (40460) 40460..41473 - 1014 WP_000845048.1 IS91 family transposase ISAzo26 Transposase
PIB66_RS24060 (41630) 41630..42103 + 474 WP_000777555.1 Dihydrofolate reductase type 1 ARG
PIB66_RS24065 (42296) 42296..43000 + 705 WP_001067845.1 IS6 family transposase IS26 Transposase
PIB66_RS24070 (43053) 43053..43529 + 477 Protein_55 PAS domain-containing protein -
PIB66_RS24075 (43597) 43597..44694 - 1098 Protein_56 TonB-dependent receptor -
PIB66_RS24080 (44751) 44751..45719 - 969 WP_013362812.1 IS5 family transposase IS903B Transposase
PIB66_RS24085 (45754) 45754..46629 - 876 WP_001617865.1 Beta-lactamase CTX-M-97 ARG
PIB66_RS24090 (46879) 46879..48141 - 1263 WP_113519521.1 IS1380 family transposase ISEcp1 Transposase
PIB66_RS24095 (48342) 48342..49373 + 1032 WP_014342102.1 Methyl-accepting chemotaxis protein McpQ VF
PIB66_RS24100 (49562) 49562..49771 - 210 Protein_61 dihydropteroate synthase -
PIB66_RS24105 (49765) 49765..50112 - 348 WP_000679427.1 Multidrug transporter EmrE ARG
PIB66_RS24110 (50304) 50304..51563 - 1260 Protein_63 Multidrug resistance protein MdtL ARG
PIB66_RS24115 (51830) 51830..52384 - 555 WP_032488579.1 aminoglycoside N-acetyltransferase AAC(6')-Ib3 -
PIB66_RS24120 (52564) 52564..53577 + 1014 WP_000845048.1 IS91 family transposase ISAzo26 Transposase
PIB66_RS24125 (53780) 53780..54130 + 351 WP_000454193.1 DUF3330 domain-containing protein -
PIB66_RS24130 (54150) 54150..54215 + 66 Protein_67 EAL domain-containing protein -
PIB66_RS24135 (54333) 54333..55097 + 765 WP_001389365.1 IS6 family transposase IS6100 Transposase
PIB66_RS24140 (55590) 55590..56174 - 585 WP_001137892.1 macrolide-binding transcriptional repressor MphR(A) -
PIB66_RS24145 (56174) 56174..57412 - 1239 WP_000004159.1 macrolide resistance MFS transporter Mrx(A) -
PIB66_RS24150 (57409) 57409..58314 - 906 WP_000219391.1 hypothetical protein ARG
PIB66_RS24155 (58436) 58436..59140 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
PIB66_RS24160 (59275) 59275..59370 + 96 WP_013362819.1 23S rRNA methyltransferase attenuation leader peptide -
PIB66_RS24165 (59496) 59496..60233 + 738 WP_013362818.1 rRNA adenine N-6-methyltransferase ARG
PIB66_RS24170 (60863) 60863..61312 + 450 WP_013362817.1 hypothetical protein -
PIB66_RS24175 (61273) 61273..61614 + 342 WP_023909256.1 60 kDa chaperonin VF
PIB66_RS24180 (61889) 61889..63373 + 1485 WP_194280410.1 IS91 family transposase ISVsa3 Transposase
PIB66_RS24185 (63498) 63498..64202 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
PIB66_RS24190 (64412) 64412..64954 - 543 WP_000587837.1 AAA family ATPase -
PIB66_RS24195 (64967) 64967..65827 - 861 WP_000557454.1 SPbeta prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD ARG
PIB66_RS24200 (65970) 65970..66932 + 963 Protein_81 IS4 family transposase IS10R Transposase
PIB66_RS24205 (67042) 67042..67947 + 906 Protein_82 IS4 family transposase IS10R Transposase
PIB66_RS24210 (67996) 67996..68700 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
PIB66_RS24215 (68942) 68942..69802 + 861 WP_000027057.1 Beta-lactamase TEM ARG
PIB66_RS24220 (69952) 69952..70050 - 99 Protein_85 IS1 family transposase -
PIB66_RS24225 (70079) 70079..71389 - 1311 WP_001262765.1 DUF262 domain-containing protein -
PIB66_RS24230 (71674) 71674..72075 - 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
PIB66_RS24235 (72008) 72008..72265 - 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
PIB66_RS24240 (72358) 72358..73011 - 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
PIB66_RS24245 (73951) 73951..74808 - 858 WP_001462098.1 incFII family plasmid replication initiator RepA -
PIB66_RS24250 (74801) 74801..74875 - 75 WP_001365705.1 RepA leader peptide Tap -
PIB66_RS24255 (75112) 75112..75369 - 258 WP_000084404.1 replication regulatory protein RepA -
PIB66_RS24260 (75609) 75609..76199 - 591 WP_000766807.1 DUF2726 domain-containing protein -
PIB66_RS24265 (76237) 76237..76446 - 210 WP_001298565.1 hemolysin expression modulator Hha -
PIB66_RS24270 (76492) 76492..76953 - 462 WP_001233838.1 thermonuclease family protein -
PIB66_RS24275 (77198) 77198..77410 - 213 WP_001309245.1 ANR family transcriptional regulator -
PIB66_RS24280 (77539) 77539..78099 - 561 WP_000139323.1 fertility inhibition protein FinO -
PIB66_RS24285 (78202) 78202..79062 - 861 WP_000704523.1 Quorum-quenching protein AidA VF
PIB66_RS24290 (79121) 79121..79867 - 747 WP_000205725.1 conjugal transfer pilus acetylase TraX -
PIB66_RS24295 (79887) 79887..85157 - 5271 WP_000948354.1 Multifunctional conjugation protein TraI Relaxase
PIB66_RS24300 (85157) 85157..87328 - 2172 WP_023910159.1 type IV conjugative transfer system coupling protein TraD -
PIB66_RS24305 (87379) 87379..88116 - 738 WP_000199905.1 hypothetical protein -
PIB66_RS24310 (88319) 88319..89050 - 732 WP_000782451.1 conjugal transfer complement resistance protein TraT -
PIB66_RS24315 (89099) 89099..89584 - 486 WP_000605870.1 hypothetical protein -
PIB66_RS24320 (89600) 89600..92422 - 2823 WP_001007039.1 conjugal transfer mating-pair stabilization protein TraG -
PIB66_RS24325 (92419) 92419..93792 - 1374 WP_000944331.1 conjugal transfer pilus assembly protein TraH -
PIB66_RS24330 (93779) 93779..94171 - 393 WP_000660699.1 F-type conjugal transfer protein TrbF -
PIB66_RS24335 (94152) 94152..94499 - 348 WP_001309242.1 P-type conjugative transfer protein TrbJ -
PIB66_RS24340 (94429) 94429..94974 - 546 WP_000059831.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
PIB66_RS24345 (94961) 94961..95245 - 285 WP_000624194.1 type-F conjugative transfer system pilin chaperone TraQ -
PIB66_RS24350 (95364) 95364..95708 - 345 WP_000556796.1 conjugal transfer protein TrbA -
PIB66_RS24355 (95722) 95722..96465 - 744 WP_001030371.1 type-F conjugative transfer system pilin assembly protein TraF -
PIB66_RS24360 (96458) 96458..96715 - 258 WP_000864353.1 conjugal transfer protein TrbE -
PIB66_RS24365 (96742) 96742..98592 - 1851 WP_000821856.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
PIB66_RS24370 (98589) 98589..99227 - 639 WP_001080256.1 type-F conjugative transfer system pilin assembly protein TrbC -
PIB66_RS24375 (99236) 99236..99541 - 306 WP_000224416.1 hypothetical protein -
PIB66_RS24380 (99571) 99571..100563 - 993 WP_000830838.1 conjugal transfer pilus assembly protein TraU -
PIB66_RS24385 (100560) 100560..101192 - 633 WP_001203728.1 type-F conjugative transfer system protein TraW -
PIB66_RS24390 (101189) 101189..101575 - 387 WP_000214084.1 type-F conjugative transfer system protein TrbI -
PIB66_RS24395 (101572) 101572..104202 - 2631 WP_000069777.1 type IV secretion system protein TraC -
PIB66_RS24400 (104328) 104328..104675 - 348 WP_000836682.1 hypothetical protein -
PIB66_RS24405 (104703) 104703..104921 - 219 WP_000556745.1 hypothetical protein -
PIB66_RS24410 (105001) 105001..105474 - 474 WP_000549568.1 hypothetical protein -
PIB66_RS24415 (105467) 105467..105880 - 414 WP_000549589.1 hypothetical protein -
PIB66_RS24420 (105873) 105873..106094 - 222 WP_001278683.1 conjugal transfer protein TraR -
PIB66_RS24425 (106229) 106229..106744 - 516 WP_000809881.1 type IV conjugative transfer system lipoprotein TraV -
PIB66_RS24430 (106741) 106741..107061 - 321 WP_001057307.1 conjugal transfer protein TrbD -
PIB66_RS24435 (107048) 107048..107614 - 567 WP_000896599.1 conjugal transfer pilus-stabilizing protein TraP -
PIB66_RS24440 (107604) 107604..109055 - 1452 WP_000146675.1 F-type conjugal transfer pilus assembly protein TraB -
PIB66_RS24445 (109055) 109055..109783 - 729 WP_001230772.1 type-F conjugative transfer system secretin TraK -
PIB66_RS24450 (109770) 109770..110336 - 567 WP_000399780.1 type IV conjugative transfer system protein TraE -
PIB66_RS24455 (110358) 110358..110669 - 312 WP_000012113.1 type IV conjugative transfer system protein TraL -
PIB66_RS24460 (110684) 110684..111043 - 360 WP_001098992.1 type IV conjugative transfer system pilin TraA -
PIB66_RS24465 (111076) 111076..111303 - 228 WP_000089263.1 conjugal transfer relaxosome protein TraY -
PIB66_RS24470 (111440) 111440..112111 - 672 WP_000283561.1 conjugal transfer transcriptional regulator TraJ -
PIB66_RS24475 (112305) 112305..112688 - 384 WP_001354030.1 conjugal transfer relaxosome DNA-binding protein TraM -
PIB66_RS24480 (113023) 113023..113613 + 591 WP_000252683.1 hypothetical protein VF
PIB66_RS24485 (113910) 113910..114731 - 822 WP_001234445.1 DUF932 domain-containing protein -
PIB66_RS24490 (114842) 114842..115138 - 297 WP_001272251.1 hypothetical protein -
PIB66_RS24495 (115438) 115438..115734 + 297 Protein_140 hypothetical protein -
PIB66_RS24500 (116053) 116053..116178 - 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
PIB66_RS24505 (116120) 116120..116269 - 150 Protein_142 plasmid maintenance protein Mok -
PIB66_RS24510 (116291) 116291..116470 + 180 WP_001309233.1 hypothetical protein -
- (116255) 116255..116479 - 225 NuclAT_0 - Antitoxin Detail
- (116255) 116255..116479 - 225 NuclAT_0 - Antitoxin Detail
- (116255) 116255..116479 - 225 NuclAT_0 - Antitoxin Detail
- (116255) 116255..116479 - 225 NuclAT_0 - Antitoxin Detail
PIB66_RS24515 (116448) 116448..117210 - 763 Protein_144 plasmid SOS inhibition protein A -
PIB66_RS24520 (117207) 117207..117641 - 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
PIB66_RS24525 (117710) 117710..119678 - 1969 Protein_146 ParB/RepB/Spo0J family partition protein -
PIB66_RS24530 (119739) 119739..119972 - 234 WP_000006003.1 DUF905 family protein -
PIB66_RS24535 (120035) 120035..120574 - 540 WP_271286764.1 single-stranded DNA-binding protein -
PIB66_RS24540 (120876) 120876..121343 + 468 Protein_149 hypothetical protein -
PIB66_RS24545 (121429) 121429..121992 - 564 WP_214132779.1 class I SAM-dependent methyltransferase -
PIB66_RS24550 (122039) 122039..123400 - 1362 WP_000170695.1 DUF3560 domain-containing protein -
PIB66_RS24555 (123452) 123452..123682 - 231 WP_000218642.1 hypothetical protein -
PIB66_RS24560 (124199) 124199..124447 + 249 WP_071557811.1 hypothetical protein -
PIB66_RS24565 (124720) 124720..124911 - 192 WP_001027493.1 hypothetical protein -
PIB66_RS24570 (124908) 124908..125330 - 423 WP_001763816.1 DUF1380 family protein -
PIB66_RS24575 (125377) 125377..125802 - 426 WP_001198928.1 antirestriction protein -
PIB66_RS24580 (126220) 126220..126996 - 777 WP_001383963.1 hypothetical protein -
PIB66_RS24585 (127047) 127047..127481 - 435 WP_000274503.1 DUF1380 family protein -
PIB66_RS24590 (127495) 127495..127716 - 222 WP_001104881.1 hypothetical protein -
PIB66_RS24595 (127717) 127717..128400 - 684 WP_000086185.1 DNA methylase -
PIB66_RS24600 (128477) 128477..128788 - 312 WP_011254640.1 hypothetical protein -
PIB66_RS24605 (128785) 128785..129687 - 903 WP_001348615.1 DUF1281 domain-containing protein -
PIB66_RS24610 (130554) 130554..131525 - 972 WP_000817036.1 ParB/RepB/Spo0J family plasmid partition protein -
PIB66_RS24615 (131525) 131525..132691 - 1167 WP_000772446.1 hypothetical protein VF
PIB66_RS24620 (133279) 133279..134034 - 756 WP_000852146.1 replication initiation protein RepE -
PIB66_RS24625 (134808) 134808..135614 - 807 WP_000016982.1 site-specific integrase -
PIB66_RS24630 (135615) 135615..135920 - 306 WP_001159868.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
PIB66_RS24635 (135922) 135922..136140 - 219 WP_000813634.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
PIB66_RS24640 (136848) 136848..137843 + 996 WP_000246635.1 hypothetical protein -
PIB66_RS24645 (137847) 137847..138779 + 933 WP_000991831.1 S-4TM family putative pore-forming effector -
PIB66_RS24650 (139077) 139077..140165 + 1089 WP_000952231.1 hypothetical protein -
PIB66_RS24655 (140158) 140158..141036 + 879 WP_225522546.1 hypothetical protein -
PIB66_RS24660 (141093) 141093..142658 - 1566 WP_001586226.1 AAA family ATPase -
PIB66_RS24665 (142969) 142969..143457 + 489 WP_024190173.1 hypothetical protein -
PIB66_RS24670 (143491) 143491..144624 - 1134 WP_000545985.1 DUF3800 domain-containing protein -
PIB66_RS24675 (144791) 144791..145180 - 390 WP_001403960.1 hypothetical protein -
PIB66_RS24680 (145126) 145126..145563 - 438 WP_016238492.1 hypothetical protein -
PIB66_RS24685 (145576) 145576..146077 - 502 Protein_178 HEPN family nuclease -
PIB66_RS24690 (146468) 146468..149089 + 2622 WP_016238490.1 hypothetical protein -
PIB66_RS24695 (149288) 149288..149518 + 231 WP_016238489.1 type II toxin-antitoxin system VapB family antitoxin -
PIB66_RS24700 (149515) 149515..149831 + 317 Protein_181 type II toxin-antitoxin system VapC family toxin -
PIB66_RS24705 (149887) 149887..150104 - 218 Protein_182 transposase -
PIB66_RS24710 (150105) 150105..150635 - 531 WP_000348884.1 GNAT family N-acetyltransferase -
PIB66_RS24715 (150639) 150639..150908 - 270 WP_016238488.1 DUF1778 domain-containing protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance