MGE detailed information
MGE type: Conjugative plasmid MGE length: 102896 bp
Accession: NZ_CP116095 Location: 1..102896 Organism: Escherichia coli strain DETEC-S560 Replicon: plasmid pDETEC68
Accession: NZ_CP116095 Location: 1..102896 Organism: Escherichia coli strain DETEC-S560 Replicon: plasmid pDETEC68
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PIC78_RS23940 (389) | 389..493 | - | 105 | Protein_1 | AAA family ATPase | - |
| PIC78_RS23945 (495) | 495..818 | - | 324 | Protein_2 | IS21 family transposase IS21 | Transposase |
| PIC78_RS23950 (1564) | 1564..2541 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| PIC78_RS23955 (2826) | 2826..3566 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| PIC78_RS23960 (3687) | 3687..3875 | - | 189 | WP_046952519.1 | hypothetical protein | - |
| PIC78_RS23965 (4242) | 4242..5411 | + | 1170 | WP_001072358.1 | hypothetical protein | - |
| PIC78_RS23970 (5637) | 5637..5812 | - | 176 | Protein_7 | IS3 family transposase | - |
| PIC78_RS23975 (6258) | 6258..6530 | - | 273 | WP_001322642.1 | Major pilu subunit operon regulatory protein PapB | VF |
| PIC78_RS23980 (7067) | 7067..7491 | - | 425 | Protein_9 | IS3 family transposase IS2 | Transposase |
| PIC78_RS23985 (7773) | 7773..9743 | + | 1971 | WP_001496335.1 | Hemin receptor | VF |
| PIC78_RS23990 (9750) | 9750..10541 | + | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| PIC78_RS23995 (10604) | 10604..11211 | - | 608 | Protein_12 | IS66 family transposase | - |
| PIC78_RS24000 (11279) | 11279..12061 | - | 783 | WP_001317493.1 | IS21 family transposase IS100kyp | Transposase |
| PIC78_RS24005 (12058) | 12058..13080 | - | 1023 | WP_271287791.1 | IS21 family transposase IS100kyp | Transposase |
| PIC78_RS24010 (13165) | 13165..14109 | - | 945 | Protein_15 | IS66 family transposase | - |
| PIC78_RS24015 (14158) | 14158..14531 | - | 374 | Protein_16 | IS66 family insertion sequence element accessory protein TnpB | - |
| PIC78_RS24020 (14556) | 14556..15261 | + | 706 | Protein_17 | IS6-like element IS26 family transposase | - |
| PIC78_RS24025 (15313) | 15313..16227 | - | 915 | Protein_18 | sodium/glutamate symporter | - |
| PIC78_RS24030 (16671) | 16671..16991 | + | 321 | WP_000562367.1 | antibiotic biosynthesis monooxygenase | - |
| PIC78_RS24035 (16984) | 16984..17370 | + | 387 | WP_000460653.1 | hypothetical protein | - |
| PIC78_RS24040 (17378) | 17378..18064 | + | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| PIC78_RS24045 (18042) | 18042..18665 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| PIC78_RS24050 (18747) | 18747..19952 | + | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| PIC78_RS24055 (20065) | 20065..20658 | - | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| PIC78_RS24060 (20746) | 20746..21162 | + | 417 | WP_000275180.1 | Transposon Tn10 TetD protein | VF |
| PIC78_RS24065 (21172) | 21172..21849 | - | 678 | Protein_26 | IS4 family transposase IS10R | Transposase |
| PIC78_RS24070 (21998) | 21998..22858 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| PIC78_RS24075 (23041) | 23041..23220 | - | 180 | Protein_28 | helix-turn-helix domain-containing protein | - |
| PIC78_RS24080 (23286) | 23286..23990 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PIC78_RS24085 (24040) | 24040..24759 | + | 720 | Protein_30 | helicase RepA family protein | - |
| PIC78_RS24090 (24746) | 24746..25597 | + | 852 | WP_000240536.1 | replication protein C, IncQ-type | - |
| PIC78_RS24095 (25905) | 25905..26720 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| PIC78_RS24100 (26781) | 26781..27584 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| PIC78_RS24105 (27584) | 27584..28420 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| PIC78_RS24110 (28481) | 28481..29185 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PIC78_RS24115 (29250) | 29250..30500 | - | 1251 | Protein_36 | transposase | - |
| PIC78_RS24120 (30575) | 30575..31243 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| PIC78_RS24125 (31279) | 31279..31515 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| PIC78_RS24130 (31512) | 31512..31874 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| PIC78_RS24135 (31892) | 31892..33586 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| PIC78_RS24140 (33638) | 33638..34060 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| PIC78_RS24145 (34096) | 34096..34371 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| PIC78_RS24150 (34385) | 34385..34735 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| PIC78_RS24155 (34807) | 34807..35241 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| PIC78_RS24165 (36294) | 36294..36695 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| PIC78_RS24170 (36628) | 36628..36885 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| PIC78_RS24175 (36978) | 36978..37286 | - | 309 | WP_226116723.1 | CPBP family intramembrane metalloprotease | - |
| PIC78_RS24180 (37228) | 37228..37620 | - | 393 | WP_000616804.1 | histidine phosphatase family protein | - |
| PIC78_RS24185 (38559) | 38559..39416 | - | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| PIC78_RS24190 (39409) | 39409..39891 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| PIC78_RS24195 (39884) | 39884..39931 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| PIC78_RS24200 (39922) | 39922..40173 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| PIC78_RS24205 (40190) | 40190..40447 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| PIC78_RS24210 (40731) | 40731..40880 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (40924) | 40924..40985 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (40924) | 40924..40985 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (40924) | 40924..40985 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (40924) | 40924..40985 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| PIC78_RS24215 (41241) | 41241..41315 | - | 75 | Protein_56 | endonuclease | - |
| PIC78_RS24220 (41561) | 41561..41773 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| PIC78_RS24225 (41909) | 41909..42469 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| PIC78_RS24230 (42572) | 42572..43432 | - | 861 | WP_000704514.1 | Quorum-quenching protein AidA | VF |
| PIC78_RS24235 (43491) | 43491..44237 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| PIC78_RS24240 (44257) | 44257..49527 | - | 5271 | WP_000986962.1 | Multifunctional conjugation protein TraI | Relaxase |
| PIC78_RS24245 (49609) | 49609..49836 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | - |
| PIC78_RS24250 (49836) | 49836..50234 | + | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| PIC78_RS24255 (50243) | 50243..52396 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| PIC78_RS24260 (52649) | 52649..53380 | - | 732 | WP_023565183.1 | conjugal transfer complement resistance protein TraT | - |
| PIC78_RS24265 (53412) | 53412..53909 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| PIC78_RS24270 (53925) | 53925..56747 | - | 2823 | WP_001007018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| PIC78_RS24275 (56744) | 56744..58117 | - | 1374 | WP_001517790.1 | conjugal transfer pilus assembly protein TraH | - |
| PIC78_RS24280 (58117) | 58117..58497 | - | 381 | WP_001389370.1 | F-type conjugal transfer protein TrbF | - |
| PIC78_RS24285 (58484) | 58484..58825 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| PIC78_RS24290 (58755) | 58755..59300 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| PIC78_RS24295 (59287) | 59287..59571 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| PIC78_RS24300 (59652) | 59652..59966 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| PIC78_RS24305 (59968) | 59968..60315 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| PIC78_RS24310 (60331) | 60331..61074 | - | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| PIC78_RS24315 (61067) | 61067..61324 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| PIC78_RS24320 (61351) | 61351..63159 | - | 1809 | WP_000821841.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| PIC78_RS24325 (63156) | 63156..63794 | - | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| PIC78_RS24330 (63803) | 63803..64795 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| PIC78_RS24335 (64792) | 64792..65424 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| PIC78_RS24340 (65421) | 65421..65807 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| PIC78_RS24345 (65804) | 65804..68431 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| PIC78_RS24350 (68591) | 68591..68812 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| PIC78_RS24355 (68947) | 68947..69462 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| PIC78_RS24360 (69459) | 69459..69710 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| PIC78_RS24365 (69722) | 69722..69919 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| PIC78_RS24370 (69906) | 69906..70496 | - | 591 | WP_001376242.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| PIC78_RS24375 (70486) | 70486..71913 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| PIC78_RS24380 (71913) | 71913..72641 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| PIC78_RS24385 (72628) | 72628..73194 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| PIC78_RS24390 (73216) | 73216..73527 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| PIC78_RS24395 (73542) | 73542..73907 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| PIC78_RS24400 (73940) | 73940..74341 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| PIC78_RS24405 (74434) | 74434..75123 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| PIC78_RS24410 (75310) | 75310..75693 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| PIC78_RS24415 (76014) | 76014..76616 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| PIC78_RS24420 (76913) | 76913..77734 | - | 822 | WP_001234426.1 | DUF932 domain-containing protein | - |
| PIC78_RS24425 (77852) | 77852..78139 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| PIC78_RS24430 (78164) | 78164..78370 | - | 207 | WP_000547968.1 | hypothetical protein | - |
| PIC78_RS24435 (78440) | 78440..78612 | + | 173 | Protein_100 | hypothetical protein | - |
| PIC78_RS24440 (78610) | 78610..78840 | - | 231 | WP_071586998.1 | hypothetical protein | - |
| PIC78_RS24445 (79060) | 79060..79185 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| PIC78_RS24450 (79127) | 79127..79276 | - | 150 | Protein_103 | plasmid maintenance protein Mok | - |
| - (79262) | 79262..79486 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (79262) | 79262..79486 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (79262) | 79262..79486 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (79262) | 79262..79486 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| PIC78_RS24455 (79298) | 79298..79486 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| PIC78_RS24460 (79455) | 79455..80217 | - | 763 | Protein_105 | plasmid SOS inhibition protein A | - |
| PIC78_RS24465 (80214) | 80214..80648 | - | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| PIC78_RS24470 (80703) | 80703..80900 | - | 198 | Protein_107 | hypothetical protein | - |
| PIC78_RS24475 (80928) | 80928..81161 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| PIC78_RS24480 (81229) | 81229..81768 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| PIC78_RS24485 (81794) | 81794..82000 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| PIC78_RS24490 (82070) | 82070..82150 | + | 81 | Protein_111 | hypothetical protein | - |
| PIC78_RS24495 (82333) | 82333..82502 | - | 170 | Protein_112 | hypothetical protein | - |
| PIC78_RS24500 (83096) | 83096..84067 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| PIC78_RS24505 (84067) | 84067..85233 | - | 1167 | WP_001238646.1 | hypothetical protein | VF |
| PIC78_RS24515 (86715) | 86715..88916 | - | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| PIC78_RS24520 (88942) | 88942..90275 | - | 1334 | Protein_117 | L-lysine N6-monooxygenase | VF |
| PIC78_RS24525 (90272) | 90272..92014 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| PIC78_RS24530 (92014) | 92014..92961 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| PIC78_RS24535 (92962) | 92962..94686 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| PIC78_RS24540 (94822) | 94822..96015 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| PIC78_RS24545 (96395) | 96395..96775 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| PIC78_RS24550 (97116) | 97116..97529 | - | 414 | Protein_123 | phosphopyruvate hydratase | - |
| PIC78_RS24555 (97527) | 97527..97784 | + | 258 | Protein_124 | Tn3 family transposase | - |
| PIC78_RS24560 (98018) | 98018..98875 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| PIC78_RS24565 (98872) | 98872..99729 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| PIC78_RS24570 (99726) | 99726..100553 | - | 828 | WP_000983710.1 | Manganese transport system ATP-binding protein MntB | VF |
| PIC78_RS24575 (100553) | 100553..101467 | - | 915 | WP_000949004.1 | putative periplasmic iron-binding protein | VF |
| PIC78_RS24580 (101823) | 101823..102520 | + | 698 | WP_103215986.1 | IS1 family transposase IS1S | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|