MGE detailed information
MGE type: Conjugative plasmid MGE length: 141731 bp
Accession: NZ_CP115994 Location: 1..141731 Organism: Enterococcus faecalis strain ESC1 Replicon: plasmid pESC2
Accession: NZ_CP115994 Location: 1..141731 Organism: Enterococcus faecalis strain ESC1 Replicon: plasmid pESC2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PE069_RS14380 (1) | 1..840 | - | 840 | WP_161972023.1 | LPXTG cell wall anchor domain-containing protein | - |
| PE069_RS14385 (863) | 863..1741 | - | 879 | WP_029888160.1 | hypothetical protein | - |
| PE069_RS14390 (1752) | 1752..2012 | - | 261 | WP_002370667.1 | hypothetical protein | - |
| PE069_RS14395 (2080) | 2080..2466 | - | 387 | WP_086321357.1 | hypothetical protein | - |
| PE069_RS14400 (2488) | 2488..2844 | - | 357 | WP_002393549.1 | pheromone response system RNA-binding regulator PrgU | - |
| PE069_RS14405 (2906) | 2906..6822 | - | 3917 | Protein_5 | Aggregation substance | VF |
| PE069_RS14410 (7112) | 7112..7447 | - | 336 | WP_002360910.1 | DUF5406 domain-containing protein | - |
| PE069_RS14415 (7591) | 7591..10266 | - | 2676 | WP_086321355.1 | surface exclusion protein SEA1/PrgA | - |
| PE069_RS14420 (10277) | 10277..10582 | - | 306 | WP_002375285.1 | hypothetical protein | - |
| PE069_RS14425 (11155) | 11155..11535 | - | 381 | WP_002394861.1 | pheromone-responsive regulatory protein R | - |
| PE069_RS14430 (12288) | 12288..13208 | + | 921 | WP_002394862.1 | helix-turn-helix transcriptional regulator | - |
| PE069_RS14435 (13263) | 13263..14411 | - | 1149 | WP_025187766.1 | TraB/GumN family protein | - |
| PE069_RS14440 (14569) | 14569..15585 | - | 1017 | WP_033593833.1 | replication initiator protein A | - |
| PE069_RS14445 (16248) | 16248..17099 | + | 852 | WP_002362419.1 | ParA family protein | - |
| PE069_RS14450 (17109) | 17109..17651 | + | 543 | WP_086321354.1 | hypothetical protein | - |
| PE069_RS14455 (18436) | 18436..18735 | - | 300 | WP_126300999.1 | type III secretion system protein PrgN | - |
| - (18844) | 18844..18935 | + | 92 | NuclAT_0 | - | - |
| - (18844) | 18844..18935 | + | 92 | NuclAT_0 | - | - |
| - (18844) | 18844..18935 | + | 92 | NuclAT_0 | - | - |
| - (18844) | 18844..18935 | + | 92 | NuclAT_0 | - | - |
| PE069_RS14460 (18975) | 18975..19064 | - | 90 | WP_153829630.1 | type I toxin-antitoxin system Fst family toxin | - |
| PE069_RS14465 (19580) | 19580..19897 | + | 318 | WP_002394802.1 | heavy metal-binding domain-containing protein | - |
| PE069_RS14470 (19933) | 19933..20601 | + | 669 | WP_002403283.1 | CPBP family intramembrane metalloprotease | - |
| PE069_RS14475 (20718) | 20718..20972 | + | 255 | WP_002394800.1 | hypothetical protein | - |
| PE069_RS14480 (21132) | 21132..21365 | - | 234 | WP_002394799.1 | hypothetical protein | - |
| PE069_RS14485 (21367) | 21367..21651 | - | 285 | WP_002394798.1 | hypothetical protein | - |
| PE069_RS14490 (21668) | 21668..22288 | - | 621 | WP_013438829.1 | Tn3 family transposase TnpR_ISAzs17 | Transposase |
| PE069_RS14495 (22492) | 22492..22722 | + | 231 | WP_002362431.1 | hypothetical protein | Antitoxin Detail |
| PE069_RS14500 (22722) | 22722..23063 | + | 342 | WP_070416029.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin Detail |
| PE069_RS14505 (23175) | 23175..24113 | + | 939 | WP_002362433.1 | hypothetical protein | - |
| PE069_RS14510 (24378) | 24378..24980 | + | 603 | WP_002362434.1 | Fic family protein | - |
| PE069_RS14515 (25119) | 25119..26275 | + | 1157 | WP_271232474.1 | IS3 family transposase ISBce13 | Transposase |
| PE069_RS14520 (26705) | 26705..27304 | + | 600 | WP_070415749.1 | Tyrosine recombinase XerC | VF |
| PE069_RS14525 (27353) | 27353..27490 | + | 138 | WP_170965568.1 | hypothetical protein | - |
| PE069_RS14530 (28098) | 28098..31292 | + | 3195 | WP_070415748.1 | helicase-related protein | - |
| PE069_RS14535 (31293) | 31293..31850 | + | 558 | WP_070415747.1 | hypothetical protein | - |
| PE069_RS14540 (31853) | 31853..33622 | + | 1770 | WP_271232475.1 | site-specific DNA-methyltransferase | - |
| PE069_RS14545 (33657) | 33657..36773 | + | 3117 | WP_070415745.1 | DEAD/DEAH box helicase family protein | - |
| PE069_RS14550 (36884) | 36884..36979 | + | 96 | Protein_34 | IS6 family transposase | - |
| PE069_RS14555 (37224) | 37224..37460 | + | 237 | WP_002287931.1 | addiction module antitoxin | - |
| PE069_RS14560 (37457) | 37457..37870 | + | 414 | WP_070415744.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| PE069_RS14565 (38395) | 38395..39573 | - | 1179 | WP_000997695.1 | IS256 family transposase ISEf1 | Transposase |
| PE069_RS14570 (39787) | 39787..41310 | + | 1524 | WP_104874991.1 | DUF2075 domain-containing protein | - |
| PE069_RS14575 (41307) | 41307..41912 | - | 606 | WP_104874990.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| PE069_RS14580 (42232) | 42232..42912 | + | 681 | WP_271232476.1 | IS6 family transposase IS1216E | Transposase |
| PE069_RS14585 (42916) | 42916..43506 | + | 591 | WP_271232481.1 | site-specific integrase | - |
| PE069_RS14590 (43679) | 43679..44221 | + | 543 | WP_128713129.1 | Fic family protein | - |
| PE069_RS14595 (44586) | 44586..45773 | + | 1188 | WP_138807330.1 | RepB family plasmid replication initiator protein | - |
| PE069_RS14600 (45777) | 45777..46367 | + | 591 | WP_128713126.1 | RepB-like protein | - |
| PE069_RS14605 (46378) | 46378..46740 | + | 363 | Protein_45 | type I restriction endonuclease subunit R | - |
| PE069_RS14610 (46795) | 46795..47475 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| PE069_RS14615 (47735) | 47735..48466 | + | 732 | WP_002360844.1 | rRNA adenine N-6-methyltransferase | ARG |
| PE069_RS14620 (48591) | 48591..48953 | - | 363 | WP_024378353.1 | EFR1 family ferrodoxin | - |
| PE069_RS14625 (49485) | 49485..49619 | - | 135 | WP_002415371.1 | hypothetical protein | - |
| PE069_RS14630 (49883) | 49883..51850 | - | 1968 | WP_105108188.1 | ABC-F type ribosomal protection protein OptrA | ARG |
| PE069_RS14635 (52182) | 52182..52352 | - | 171 | WP_105461295.1 | AraC family transcriptional regulator | - |
| PE069_RS14640 (52538) | 52538..53965 | - | 1428 | WP_065813868.1 | chloramphenicol/florfenicol efflux MFS transporter FexA | ARG |
| PE069_RS14645 (54219) | 54219..54362 | - | 144 | WP_002360221.1 | hypothetical protein | - |
| PE069_RS14650 (54816) | 54816..54941 | + | 126 | Protein_54 | JAB domain-containing protein | - |
| PE069_RS14655 (55069) | 55069..55506 | + | 438 | WP_174116110.1 | hypothetical protein | - |
| PE069_RS14660 (55834) | 55834..56514 | + | 681 | WP_271232477.1 | IS6 family transposase IS1216E | Transposase |
| PE069_RS14665 (56576) | 56576..56776 | + | 201 | WP_242458402.1 | helix-turn-helix domain-containing protein | - |
| PE069_RS14670 (56766) | 56766..57380 | + | 615 | WP_271232478.1 | bacitracin resistance transcriptional activator BcrR | - |
| PE069_RS14675 (57563) | 57563..58480 | + | 918 | WP_104765562.1 | ATP-binding cassette domain-containing protein | - |
| PE069_RS14680 (58473) | 58473..59222 | + | 750 | WP_000933358.1 | ABC transporter permease | - |
| PE069_RS14685 (59222) | 59222..60052 | + | 831 | WP_128713131.1 | undecaprenyl-diphosphate phosphatase | - |
| PE069_RS14690 (60249) | 60249..60929 | - | 681 | WP_161978276.1 | IS6 family transposase ISEnfa1 | Transposase |
| PE069_RS14695 (61004) | 61004..61135 | + | 132 | Protein_63 | IS1380 family transposase | - |
| PE069_RS14700 (61387) | 61387..61779 | + | 393 | WP_000084745.1 | pyridoxamine 5'-phosphate oxidase family protein | - |
| PE069_RS14705 (61967) | 61967..62647 | + | 681 | WP_013646119.1 | IS6 family transposase IS1216E | Transposase |
| PE069_RS14710 (62935) | 62935..63321 | - | 387 | WP_271232479.1 | helix-turn-helix transcriptional regulator | - |
| PE069_RS14715 (63409) | 63409..64212 | + | 804 | WP_116495285.1 | MFS transporter | - |
| PE069_RS14720 (64278) | 64278..64598 | + | 321 | WP_116495286.1 | hypothetical protein | - |
| PE069_RS14725 (64821) | 64821..65639 | - | 819 | WP_271232480.1 | MurR/RpiR family transcriptional regulator | - |
| PE069_RS14730 (65796) | 65796..66503 | + | 708 | WP_002358533.1 | N-acetylmannosamine-6-phosphate 2-epimerase | - |
| PE069_RS14735 (66496) | 66496..67998 | + | 1503 | WP_010817772.1 | PTS transporter subunit EIIC | - |
| PE069_RS14740 (68009) | 68009..68491 | + | 483 | WP_010817773.1 | PTS glucose transporter subunit IIA | - |
| PE069_RS14745 (68731) | 68731..69411 | + | 681 | WP_071621256.1 | IS6 family transposase ISS1N | Transposase |
| PE069_RS14750 (69645) | 69645..70247 | - | 603 | WP_002367780.1 | Fic family protein | - |
| PE069_RS14755 (70515) | 70515..71453 | - | 939 | WP_002394789.1 | hypothetical protein | - |
| PE069_RS14760 (71565) | 71565..71906 | - | 342 | WP_002394791.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin Detail |
| PE069_RS14765 (71906) | 71906..72136 | - | 231 | WP_002362431.1 | hypothetical protein | Antitoxin Detail |
| PE069_RS14770 (72340) | 72340..72960 | + | 621 | WP_002367784.1 | Tn3 family transposase TnpR_ISAli20 | Transposase |
| PE069_RS14775 (72950) | 72950..73264 | + | 315 | WP_002367785.1 | hypothetical protein | - |
| PE069_RS14780 (73258) | 73258..73464 | + | 207 | WP_002367786.1 | hypothetical protein | - |
| PE069_RS14785 (73624) | 73624..73818 | + | 195 | WP_002367787.1 | hypothetical protein | - |
| PE069_RS14790 (73830) | 73830..74021 | + | 192 | WP_002367788.1 | hypothetical protein | - |
| PE069_RS14795 (74191) | 74191..74406 | + | 216 | WP_002367791.1 | leucocin A/sakacin P family class II bacteriocin | - |
| PE069_RS14800 (74407) | 74407..74748 | + | 342 | WP_002367792.1 | bacteriocin immunity protein | - |
| PE069_RS14805 (75164) | 75164..75682 | + | 519 | WP_002367793.1 | hypothetical protein | - |
| PE069_RS14810 (75630) | 75630..75845 | + | 216 | WP_002415356.1 | hypothetical protein | - |
| PE069_RS14815 (75937) | 75937..76023 | + | 87 | WP_012881081.1 | type I toxin-antitoxin system Fst family toxin | - |
| PE069_RS14820 (76280) | 76280..76576 | + | 297 | WP_002367795.1 | hypothetical protein | - |
| PE069_RS14825 (76711) | 76711..77343 | + | 633 | WP_002367796.1 | AbiV family abortive infection protein | - |
| PE069_RS14830 (78012) | 78012..78383 | - | 372 | WP_002358205.1 | hypothetical protein | - |
| PE069_RS14835 (78376) | 78376..79221 | - | 846 | WP_000239313.1 | AAA family ATPase | - |
| PE069_RS14840 (79693) | 79693..80703 | + | 1011 | WP_002367743.1 | replication initiator protein A | - |
| PE069_RS14845 (80834) | 80834..81502 | + | 669 | WP_002362416.1 | type II CAAX endopeptidase family protein | - |
| PE069_RS14850 (81545) | 81545..83170 | + | 1626 | Protein_94 | peptide ABC transporter substrate-binding protein | - |
| PE069_RS14855 (83348) | 83348..83470 | + | 123 | WP_002415665.1 | hypothetical protein | - |
| PE069_RS14860 (83527) | 83527..84027 | + | 501 | WP_229294411.1 | hypothetical protein | - |
| PE069_RS14865 (83948) | 83948..85212 | - | 1265 | Protein_97 | hypothetical protein | Relaxase |
| PE069_RS14870 (85502) | 85502..86149 | - | 648 | WP_002415230.1 | Chloramphenicol acetyltransferase | ARG |
| PE069_RS14875 (86284) | 86284..86595 | - | 312 | Protein_99 | replication initiation protein | - |
| PE069_RS14880 (87191) | 87191..88567 | - | 1377 | WP_104670783.1 | tetracycline efflux MFS transporter Tet(L) | ARG |
| PE069_RS14885 (88761) | 88761..90680 | - | 1920 | WP_001574275.1 | tetracycline resistance ribosomal protection protein Tet(M) | VF |
| PE069_RS14890 (90696) | 90696..90812 | - | 117 | WP_001791010.1 | tetracycline resistance determinant leader peptide | - |
| PE069_RS14895 (91057) | 91057..91989 | - | 933 | WP_001224319.1 | conjugal transfer protein | - |
| PE069_RS14900 (91986) | 91986..92987 | - | 1002 | WP_001574272.1 | hypothetical protein | VF |
| PE069_RS14905 (92984) | 92984..95161 | - | 2178 | WP_116495283.1 | YtxH domain-containing protein | - |
| PE069_RS14910 (95164) | 95164..96198 | - | 1035 | Protein_106 | ATP-binding protein | - |
| PE069_RS14915 (96275) | 96275..96955 | + | 681 | WP_013646119.1 | IS6 family transposase IS1216E | Transposase |
| PE069_RS14920 (96959) | 96959..97549 | + | 591 | WP_271232481.1 | site-specific integrase | - |
| PE069_RS14925 (97722) | 97722..98264 | + | 543 | WP_128713129.1 | Fic family protein | - |
| PE069_RS14930 (98553) | 98553..99524 | - | 972 | Protein_110 | amidase | - |
| PE069_RS14935 (99555) | 99555..100061 | + | 507 | WP_271232482.1 | IS30 family transposase ISApl1 | Transposase |
| PE069_RS14940 (100133) | 100133..101746 | - | 1614 | WP_002333004.1 | hypothetical protein | - |
| PE069_RS14945 (101770) | 101770..102651 | - | 882 | WP_002326774.1 | Multidrug efflux system ATP-binding protein | VF |
| PE069_RS14950 (102962) | 102962..103558 | + | 597 | WP_085442989.1 | TetR/AcrR family transcriptional regulator | - |
| PE069_RS14955 (103727) | 103727..104131 | - | 405 | Protein_115 | DnaJ domain-containing protein | - |
| PE069_RS14960 (104262) | 104262..105125 | - | 864 | WP_002333003.1 | zeta toxin family protein | Toxin Detail |
| PE069_RS14965 (105127) | 105127..105399 | - | 273 | WP_002333002.1 | antitoxin | Antitoxin Detail |
| PE069_RS14970 (105417) | 105417..105632 | - | 216 | WP_001835296.1 | peptide-binding protein | - |
| PE069_RS14975 (105724) | 105724..106620 | - | 897 | WP_104681373.1 | ParA family protein | - |
| PE069_RS14980 (106723) | 106723..108558 | - | 1836 | WP_232035937.1 | type IA DNA topoisomerase | - |
| PE069_RS14985 (108788) | 108788..109006 | + | 219 | WP_271232473.1 | hypothetical protein | - |
| PE069_RS14990 (109079) | 109079..111031 | + | 1953 | WP_000163792.1 | hypothetical protein | - |
| PE069_RS14995 (111103) | 111103..111600 | - | 498 | WP_000868795.1 | IS1595 family transposase ISSsu9 | ARG |
| PE069_RS15000 (112144) | 112144..112824 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| PE069_RS15005 (113440) | 113440..114234 | - | 795 | WP_001096887.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| PE069_RS15010 (114238) | 114238..114975 | - | 738 | WP_104681337.1 | rRNA adenine N-6-methyltransferase | ARG |
| PE069_RS15015 (115100) | 115100..115183 | - | 84 | WP_001814874.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| PE069_RS15020 (115640) | 115640..116320 | + | 681 | WP_162499548.1 | IS6 family transposase ISEnfa1 | Transposase |
| PE069_RS15025 (116518) | 116518..117348 | - | 831 | WP_002367748.1 | undecaprenyl-diphosphate phosphatase | - |
| PE069_RS15030 (117348) | 117348..118097 | - | 750 | WP_002367750.1 | ABC transporter permease | - |
| PE069_RS15035 (118090) | 118090..119007 | - | 918 | WP_033626719.1 | ATP-binding cassette domain-containing protein | - |
| PE069_RS15040 (119182) | 119182..119796 | - | 615 | WP_013438838.1 | bacitracin resistance transcriptional activator BcrR | - |
| PE069_RS15045 (119786) | 119786..120112 | - | 327 | WP_002367753.1 | DNA-binding protein | - |
| PE069_RS15050 (120149) | 120149..120313 | + | 165 | WP_001808810.1 | helix-turn-helix transcriptional regulator | - |
| PE069_RS15055 (120352) | 120352..121032 | + | 681 | Protein_135 | IS6 family transposase | - |
| PE069_RS15060 (121414) | 121414..121743 | - | 330 | WP_232035935.1 | hypothetical protein | - |
| PE069_RS15065 (121785) | 121785..122465 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| PE069_RS15070 (122939) | 122939..123019 | + | 81 | WP_228770506.1 | putative holin-like toxin | - |
| PE069_RS15075 (123238) | 123238..123714 | - | 477 | WP_000615486.1 | single-stranded DNA-binding protein | - |
| PE069_RS15080 (123854) | 123854..125188 | - | 1335 | WP_001036756.1 | PcfJ domain-containing protein | - |
| PE069_RS15085 (125185) | 125185..125961 | - | 777 | WP_000347505.1 | Cas9 inhibitor AcrIIA9 family protein | - |
| PE069_RS15090 (126123) | 126123..126389 | - | 267 | WP_001245899.1 | hypothetical protein | - |
| PE069_RS15095 (126396) | 126396..126578 | - | 183 | WP_001808764.1 | hypothetical protein | - |
| PE069_RS15100 (126996) | 126996..127484 | - | 489 | WP_086321361.1 | hypothetical protein | - |
| PE069_RS15105 (127490) | 127490..128275 | - | 786 | WP_002360778.1 | hypothetical protein | Relaxase |
| PE069_RS15110 (128798) | 128798..131056 | - | 2259 | WP_086321360.1 | hypothetical protein | VF |
| PE069_RS15115 (131043) | 131043..133388 | - | 2346 | WP_010831073.1 | hypothetical protein | - |
| PE069_RS15120 (133406) | 133406..133801 | - | 396 | WP_002383639.1 | hypothetical protein | - |
| PE069_RS15125 (133758) | 133758..136250 | - | 2493 | WP_010773420.1 | ATP-binding protein | - |
| PE069_RS15130 (136355) | 136355..136813 | - | 459 | WP_002365911.1 | single-stranded DNA-binding protein | - |
| PE069_RS15135 (136906) | 136906..137388 | - | 483 | WP_002360790.1 | hypothetical protein | - |
| PE069_RS15140 (137420) | 137420..137809 | - | 390 | WP_002360791.1 | TcpE family conjugal transfer membrane protein | - |
| PE069_RS15145 (137809) | 137809..138069 | - | 261 | WP_010706916.1 | hypothetical protein | - |
| PE069_RS15150 (138074) | 138074..139108 | - | 1035 | WP_002403100.1 | conjugal transfer protein | - |
| PE069_RS15155 (139101) | 139101..139415 | - | 315 | WP_002360796.1 | hypothetical protein | - |
| PE069_RS15160 (139415) | 139415..139831 | - | 417 | WP_002406548.1 | thioredoxin domain-containing protein | - |
| PE069_RS15165 (139815) | 139815..140432 | - | 618 | WP_086321359.1 | hypothetical protein | - |
| PE069_RS15170 (140435) | 140435..141706 | - | 1272 | WP_010773576.1 | CHAP domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|