NZ_CP1146181..149649

MGE detailed information

MGE type: Non-Mobilizable plasmid        MGE length: 149649 bp
Accession: NZ_CP114618        Location: 1..149649         Organism: Enterococcus faecium strain EF0656       Replicon: plasmid pEF0656-1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O4N81_RS13775 (O4N81_13775) 299..1759 - 1461 WP_002347152.1 toprim domain-containing protein -
O4N81_RS13780 (O4N81_13780) 1820..4192 - 2373 WP_002305801.1 ArdC-like ssDNA-binding domain-containing protein -
O4N81_RS13785 (O4N81_13785) 4602..5852 + 1251 WP_002297404.1 IS110 family transposase ISSpn10 Transposase
O4N81_RS13790 (O4N81_13790) 6089..6430 - 342 WP_002295674.1 DUF5406 family protein -
O4N81_RS13795 (O4N81_13795) 7049..7381 - 333 WP_002323647.1 type IV conjugative transfer system protein TraE -
O4N81_RS13800 (O4N81_13800) 8205..9245 - 1041 WP_002326172.1 replication initiator protein A -
O4N81_RS13805 (O4N81_13805) 10411..10497 + 87 Protein_7 single-stranded DNA-binding protein -
O4N81_RS13810 (O4N81_13810) 11135..11275 + 141 WP_002290398.1 hypothetical protein -
O4N81_RS13815 (O4N81_13815) 11498..12646 - 1149 WP_002323589.1 IS200-IS605 family transposase ISEfa4 Transposase
O4N81_RS13820 (O4N81_13820) 12663..13067 - 405 WP_002287522.1 IS200-IS605 family transposase ISEfa4 Transposase
O4N81_RS13825 (O4N81_13825) 13426..13680 + 255 WP_002323399.1 hypothetical protein -
O4N81_RS13830 (O4N81_13830) 13681..13998 + 318 WP_002290394.1 type II toxin-antitoxin system RelE/ParE family toxin -
O4N81_RS13835 (O4N81_13835) 14557..15492 + 936 WP_002323400.1 hypothetical protein -
O4N81_RS13840 (O4N81_13840) 15586..16494 + 909 Protein_14 IS982 family transposase ISEfm1 Transposase
O4N81_RS13845 (O4N81_13845) 16576..17430 + 855 WP_002338109.1 AraC family transcriptional regulator -
O4N81_RS13850 (O4N81_13850) 17527..19776 + 2250 WP_002314387.1 alpha-galactosidase -
O4N81_RS13855 (O4N81_13855) 19779..20954 + 1176 WP_002336205.1 MFS transporter -
O4N81_RS13860 (O4N81_13860) 20957..21865 - 909 Protein_18 IS982 family transposase ISEfm1 Transposase
O4N81_RS13865 (O4N81_13865) 22099..22362 + 264 WP_002297422.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin Detail
O4N81_RS13870 (O4N81_13870) 22362..22634 + 273 WP_002314366.1 Txe/YoeB family addiction module toxin Toxin Detail
O4N81_RS13875 (O4N81_13875) 22711..23040 + 330 WP_002292678.1 AbrB family transcriptional regulator -
O4N81_RS13880 (O4N81_13880) 23030..23317 + 288 WP_076713767.1 type II toxin-antitoxin system RelE/ParE family toxin -
O4N81_RS13885 (O4N81_13885) 23602..24459 + 858 WP_002292680.1 ParA family protein -
O4N81_RS13890 (O4N81_13890) 24460..25008 + 549 WP_002292681.1 hypothetical protein -
O4N81_RS13895 (O4N81_13895) 25124..26419 - 1296 WP_002297218.1 ISL3 family transposase ISEfa11 Transposase
O4N81_RS13900 (O4N81_13900) 26796..27476 + 681 Protein_26 IS6 family transposase IS1297 Transposase
O4N81_RS13905 (O4N81_13905) 27761..28948 + 1188 WP_002296840.1 IS256 family transposase IS16 Transposase
O4N81_RS13910 (O4N81_13910) 29926..30879 - 954 WP_085807902.1 IS30 family transposase IS1252 Transposase
O4N81_RS13915 (O4N81_13915) 31344..31898 + 555 WP_002290383.1 tyrosine-type recombinase/integrase -
O4N81_RS13920 (O4N81_13920) 32071..32544 - 474 WP_002290382.1 IS91 family transposase ISCARN110 Transposase
O4N81_RS13925 (O4N81_13925) 32556..33092 + 537 WP_002342357.1 VOC family protein -
O4N81_RS13930 (O4N81_13930) 33132..33503 + 372 WP_002290380.1 VOC family protein -
O4N81_RS13935 (O4N81_13935) 33787..35058 + 1272 WP_002290379.1 substrate-binding domain-containing protein -
O4N81_RS13940 (O4N81_13940) 35303..36328 + 1026 WP_002338088.1 LacI family DNA-binding transcriptional regulator -
O4N81_RS13945 (O4N81_13945) 36466..36591 + 126 WP_002290377.1 hypothetical protein -
O4N81_RS13950 (O4N81_13950) 36622..37731 + 1110 WP_002350067.1 sugar ABC transporter substrate-binding protein -
O4N81_RS13955 (O4N81_13955) 37814..38710 + 897 Protein_37 sugar ABC transporter permease -
O4N81_RS13960 (O4N81_13960) 38726..39550 + 825 WP_002350071.1 carbohydrate ABC transporter permease -
O4N81_RS13965 (O4N81_13965) 39582..40892 + 1311 WP_002329911.1 alpha-glucosidase/alpha-galactosidase -
O4N81_RS13970 (O4N81_13970) 41040..42299 + 1260 WP_002290371.1 extracellular solute-binding protein -
O4N81_RS13975 (O4N81_13975) 42309..43181 + 873 WP_002290370.1 sugar ABC transporter permease -
O4N81_RS13980 (O4N81_13980) 43193..44023 + 831 WP_002290368.1 carbohydrate ABC transporter permease -
O4N81_RS13985 (O4N81_13985) 44063..46246 + 2184 WP_002290367.1 alpha-galactosidase -
O4N81_RS13990 (O4N81_13990) 46307..47527 + 1221 WP_002342361.1 alpha-amylase family glycosyl hydrolase -
O4N81_RS13995 (O4N81_13995) 47524..48984 + 1461 WP_002335326.1 sucrose phosphorylase -
O4N81_RS14000 (O4N81_14000) 49061..50167 + 1107 Protein_46 IS4 family transposase IS641 Transposase
O4N81_RS14005 (O4N81_14005) 50489..50698 + 210 WP_002290357.1 DUF3173 domain-containing protein -
O4N81_RS14010 (O4N81_14010) 50691..50840 + 150 WP_002290356.1 hypothetical protein -
O4N81_RS14015 (O4N81_14015) 50994..51659 + 666 WP_002324528.1 site-specific integrase -
O4N81_RS14020 (O4N81_14020) 51943..53028 - 1086 WP_002290352.1 tyrosine recombinase XerS -
O4N81_RS14025 (O4N81_14025) 53182..54141 - 960 WP_002303350.1 IS30 family transposase IS1062 Transposase
O4N81_RS14030 (O4N81_14030) 54428..54661 + 234 WP_002290351.1 addiction module antitoxin -
O4N81_RS14035 (O4N81_14035) 54658..55065 + 408 WP_002329899.1 type II toxin-antitoxin system death-on-curing family toxin -
O4N81_RS14040 (O4N81_14040) 55516..56025 - 510 WP_002295345.1 hypothetical protein -
O4N81_RS14045 (O4N81_14045) 56141..57303 + 1163 Protein_55 IS3 family transposase IS1485 Transposase
O4N81_RS14050 (O4N81_14050) 57775..58674 - 900 WP_002333402.1 aldose 1-epimerase family protein -
O4N81_RS14055 (O4N81_14055) 58695..58968 - 274 Protein_57 DUF3884 family protein -
O4N81_RS14060 (O4N81_14060) 58991..60397 - 1407 WP_002333401.1 6-phospho-beta-galactosidase -
O4N81_RS14065 (O4N81_14065) 60539..62245 - 1707 WP_002290549.1 lactose-specific PTS transporter subunit EIIC -
O4N81_RS14070 (O4N81_14070) 62245..62562 - 318 WP_002290550.1 PTS lactose/cellobiose transporter subunit IIA -
O4N81_RS14075 (O4N81_14075) 62590..63570 - 981 WP_002290551.1 tagatose-bisphosphate aldolase -
O4N81_RS14080 (O4N81_14080) 63573..64505 - 933 WP_002290553.1 tagatose-6-phosphate kinase -
O4N81_RS14085 (O4N81_14085) 64516..65031 - 516 WP_002290554.1 galactose-6-phosphate isomerase subunit LacB -
O4N81_RS14090 (O4N81_14090) 65048..65473 - 426 WP_002290555.1 galactose-6-phosphate isomerase subunit LacA -
O4N81_RS14095 (O4N81_14095) 65962..66729 + 768 WP_002290556.1 DeoR/GlpR family DNA-binding transcription regulator -
O4N81_RS14100 (O4N81_14100) 66734..67492 + 759 WP_002333400.1 HAD family hydrolase -
O4N81_RS14105 (O4N81_14105) 67522..68684 - 1163 Protein_67 IS3 family transposase IS1485 Transposase
O4N81_RS14110 (O4N81_14110) 68761..69466 - 706 Protein_68 DNA topoisomerase -
O4N81_RS14115 (O4N81_14115) 69558..69938 - 381 Protein_69 Tn3 family transposase TnpR_ISMex38 Transposase
O4N81_RS14120 (O4N81_14120) 70214..70837 + 624 WP_002328880.1 Tn3 family transposase TnpR_TnAs2 Transposase
O4N81_RS14125 (O4N81_14125) 70834..71271 - 438 WP_002328879.1 hypothetical protein -
O4N81_RS14130 (O4N81_14130) 71545..72723 - 1179 WP_000997695.1 IS256 family transposase ISEf1 Transposase
O4N81_RS14135 (O4N81_14135) 73023..73718 + 696 WP_002328878.1 PHP domain-containing protein -
O4N81_RS14140 (O4N81_14140) 73755..74252 - 498 WP_002328877.1 GNAT family N-acetyltransferase -
O4N81_RS14145 (O4N81_14145) 74308..75216 - 909 WP_002328876.1 IS982 family transposase ISEfm1 Transposase
O4N81_RS14150 (O4N81_14150) 76004..77230 + 1227 WP_010729769.1 site-specific integrase -
O4N81_RS14155 (O4N81_14155) 77388..78005 - 618 WP_002323453.1 Tn3 family transposase TnpR_TnAs1 Transposase
O4N81_RS14160 (O4N81_14160) 78688..79683 - 996 WP_002305056.1 LacI family DNA-binding transcriptional regulator -
O4N81_RS14165 (O4N81_14165) 79778..80650 - 873 WP_002322785.1 ROK family protein -
O4N81_RS14170 (O4N81_14170) 80663..82090 - 1428 WP_002361237.1 glycoside hydrolase family 32 protein -
O4N81_RS14175 (O4N81_14175) 82144..83418 - 1275 WP_002323715.1 MFS transporter -
O4N81_RS14180 (O4N81_14180) 83721..84674 + 954 WP_002286097.1 IS30 family transposase IS1252 Transposase
O4N81_RS14185 (O4N81_14185) 84848..85279 - 432 WP_002305052.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin Detail
O4N81_RS14190 (O4N81_14190) 85313..85465 - 153 WP_224451579.1 type II toxin-antitoxin system HicA family toxin Toxin Detail
O4N81_RS14195 (O4N81_14195) 85559..85738 - 180 Protein_85 hypothetical protein -
O4N81_RS14200 (O4N81_14200) 85754..85954 - 201 WP_002324500.1 hypothetical protein -
O4N81_RS14205 (O4N81_14205) 86119..86814 - 696 WP_002305050.1 hypothetical protein -
O4N81_RS14210 (O4N81_14210) 86807..87004 - 198 Protein_88 hypothetical protein -
O4N81_RS14215 (O4N81_14215) 87079..87759 + 681 WP_001015311.1 IS6 family transposase IS1216E Transposase
O4N81_RS14220 (O4N81_14220) 87814..87984 - 171 Protein_90 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
O4N81_RS14225 (O4N81_14225) 87997..88593 - 597 WP_002299811.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
O4N81_RS14230 (O4N81_14230) 88674..88823 - 150 WP_002295632.1 hypothetical protein -
O4N81_RS14235 (O4N81_14235) 88839..90948 - 2110 Protein_93 DNA topoisomerase III -
O4N81_RS14240 (O4N81_14240) 90959..91756 - 798 Protein_94 toprim domain-containing protein -
O4N81_RS14245 (O4N81_14245) 91804..92484 - 681 WP_001015311.1 IS6 family transposase IS1216E Transposase
O4N81_RS14250 (O4N81_14250) 92561..93295 + 735 Protein_96 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
O4N81_RS14255 (O4N81_14255) 93298..93783 + 486 Protein_97 single-stranded DNA-binding protein -
O4N81_RS14260 (O4N81_14260) 93828..94061 + 234 WP_002303482.1 hypothetical protein -
O4N81_RS14265 (O4N81_14265) 94220..94364 - 145 Protein_99 putative holin-like toxin -
O4N81_RS14270 (O4N81_14270) 94556..94756 + 201 WP_227005125.1 hypothetical protein -
O4N81_RS14275 (O4N81_14275) 95204..95410 + 207 WP_002324499.1 hypothetical protein -
O4N81_RS14280 (O4N81_14280) 95410..95661 + 252 WP_002287517.1 hypothetical protein -
O4N81_RS14285 (O4N81_14285) 95677..95922 + 246 Protein_103 hypothetical protein -
O4N81_RS14290 (O4N81_14290) 95979..96659 - 681 WP_001015311.1 IS6 family transposase IS1216E Transposase
O4N81_RS14295 (O4N81_14295) 96795..97406 - 612 WP_002305817.1 Tn3 family transposase TnpR_TnAs2 Transposase
O4N81_RS14300 (O4N81_14300) 97446..98228 - 783 WP_002305134.1 helix-turn-helix domain-containing protein -
O4N81_RS14305 (O4N81_14305) 98257..98562 - 306 Protein_107 DNA-binding protein -
O4N81_RS14310 (O4N81_14310) 98634..99796 + 1163 WP_087121905.1 IS3 family transposase ISEfa8 Transposase
O4N81_RS14315 (O4N81_14315) 99881..100993 - 1113 WP_269528400.1 hypothetical protein VF
O4N81_RS14320 (O4N81_14320) 101042..101938 - 897 WP_002305840.1 helix-turn-helix transcriptional regulator -
O4N81_RS14325 (O4N81_14325) 102133..102654 - 522 WP_002311883.1 helix-turn-helix transcriptional regulator -
O4N81_RS14330 (O4N81_14330) 102846..103034 + 189 WP_002305130.1 type II toxin-antitoxin system HicA family toxin -
O4N81_RS14335 (O4N81_14335) 103080..103457 + 378 WP_002305129.1 type II toxin-antitoxin system HicB family antitoxin -
O4N81_RS14340 (O4N81_14340) 104017..104484 - 468 WP_233143248.1 hypothetical protein -
O4N81_RS14345 (O4N81_14345) 104578..105258 - 681 WP_001015311.1 IS6 family transposase IS1216E Transposase
O4N81_RS14350 (O4N81_14350) 105334..106541 - 1208 Protein_116 hypothetical protein -
O4N81_RS14355 (O4N81_14355) 106951..108201 + 1251 WP_060808286.1 IS110 family transposase ISSpn10 Transposase
O4N81_RS14360 (O4N81_14360) 108337..108531 - 195 WP_002322479.1 hypothetical protein -
O4N81_RS14365 (O4N81_14365) 108779..109920 + 1142 WP_086968564.1 IS3 family transposase ISBce13 Transposase
O4N81_RS14370 (O4N81_14370) 110081..110401 - 321 Protein_120 hypothetical protein -
O4N81_RS14375 (O4N81_14375) 110422..112014 - 1593 WP_002296379.1 hypothetical protein Relaxase
O4N81_RS14380 (O4N81_14380) 112033..112455 - 423 WP_010729773.1 hypothetical protein -
O4N81_RS14385 (O4N81_14385) 112457..112753 - 297 WP_002296377.1 hypothetical protein -
O4N81_RS14390 (O4N81_14390) 112985..113254 - 270 WP_002305788.1 hypothetical protein -
O4N81_RS14395 (O4N81_14395) 113275..113800 - 526 Protein_125 hypothetical protein -
O4N81_RS14400 (O4N81_14400) 113800..114480 + 681 WP_001015311.1 IS6 family transposase IS1216E Transposase
O4N81_RS14405 (O4N81_14405) 114582..115901 - 1320 WP_002300494.1 HAMP domain-containing sensor histidine kinase -
O4N81_RS14410 (O4N81_14410) 115898..116551 - 654 WP_002285815.1 Transcriptional regulatory protein QseB VF
O4N81_RS14415 (O4N81_14415) 116839..117359 + 521 Protein_129 transposase family protein -
O4N81_RS14420 (O4N81_14420) 117261..118076 - 816 WP_002302255.1 aminotransferase class V-fold PLP-dependent enzyme -
O4N81_RS14425 (O4N81_14425) 118101..118286 - 186 WP_016922460.1 hypothetical protein -
O4N81_RS14430 (O4N81_14430) 118513..119745 + 1233 Protein_132 ISL3 family transposase ISEfa11 Transposase
O4N81_RS14435 (O4N81_14435) 119893..120924 - 1032 WP_002302261.1 Vitamin B12 import ATP-binding protein BtuD VF
O4N81_RS14440 (O4N81_14440) 120931..121761 - 831 WP_002313180.1 ABC transporter permease -
O4N81_RS14445 (O4N81_14445) 121758..122573 - 816 WP_002330693.1 ABC transporter permease subunit -
O4N81_RS14450 (O4N81_14450) 122570..123394 - 825 WP_002302267.1 alkaline phosphatase family protein -
O4N81_RS14455 (O4N81_14455) 123384..124484 - 1101 WP_002302268.1 extracellular solute-binding protein -
O4N81_RS14460 (O4N81_14460) 124662..125447 + 786 WP_002302270.1 PHP domain-containing protein -
O4N81_RS14465 (O4N81_14465) 125480..125863 + 384 WP_002330694.1 hypothetical protein -
O4N81_RS14470 (O4N81_14470) 126039..126275 + 237 WP_002322470.1 Putative bifunctional phosphatase/peptidyl-prolyl cis-trans isomerase VF
O4N81_RS14475 (O4N81_14475) 126353..127324 - 972 WP_002302275.1 radical SAM protein -
O4N81_RS14480 (O4N81_14480) 127958..129418 + 1461 Protein_142 IS1182 family transposase ISEfa7 Transposase
O4N81_RS14485 (O4N81_14485) 129341..129670 - 330 WP_228780303.1 IS1182 family transposase ISEfa7 Transposase
O4N81_RS14490 (O4N81_14490) 129884..131260 - 1377 WP_002301195.1 ABC transporter permease -
O4N81_RS14495 (O4N81_14495) 131260..131916 - 657 WP_002298083.1 putative ABC transporter ATP-binding protein VF
O4N81_RS14500 (O4N81_14500) 131926..133203 - 1278 WP_002301194.1 ABC transporter permease -
O4N81_RS14505 (O4N81_14505) 133222..133377 - 156 Protein_147 4Fe-4S binding protein -
O4N81_RS14510 (O4N81_14510) 133453..134615 + 1163 WP_087121905.1 IS3 family transposase ISEfa8 Transposase
O4N81_RS14515 (O4N81_14515) 134645..135094 - 450 WP_010729386.1 TlpA disulfide reductase family protein -
O4N81_RS14520 (O4N81_14520) 135250..135792 - 543 WP_002298088.1 hypothetical protein -
O4N81_RS14525 (O4N81_14525) 136067..136710 + 644 Protein_151 transposase -
O4N81_RS14530 (O4N81_14530) 136786..137466 + 681 WP_002331383.1 IS6 family transposase IS1216E Transposase
O4N81_RS14535 (O4N81_14535) 137655..138239 - 585 WP_002299575.1 Tn3 family transposase TnBth3 Transposase
O4N81_RS14540 (O4N81_14540) 138450..138653 - 204 WP_002299573.1 hypothetical protein -
O4N81_RS14545 (O4N81_14545) 138663..139085 - 423 WP_002303116.1 hypothetical protein -
O4N81_RS14550 (O4N81_14550) 139323..139937 + 615 WP_001261742.1 Tn3 family transposase TnpR_TnAs2 Transposase
O4N81_RS14555 (O4N81_14555) 140102..140926 - 825 WP_001809248.1 hypothetical protein -
O4N81_RS14560 (O4N81_14560) 140950..141105 - 156 WP_002347142.1 hypothetical protein -
O4N81_RS14565 (O4N81_14565) 141564..141821 - 258 WP_000588503.1 Txe/YoeB family addiction module toxin Toxin Detail
O4N81_RS14570 (O4N81_14570) 141814..142083 - 270 WP_000388479.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin Detail
O4N81_RS14575 (O4N81_14575) 142214..142393 - 180 WP_001120991.1 hypothetical protein -
O4N81_RS14580 (O4N81_14580) 142409..142609 - 201 WP_002347143.1 hypothetical protein -
O4N81_RS14585 (O4N81_14585) 142774..143481 - 708 WP_002303117.1 hypothetical protein -
O4N81_RS14590 (O4N81_14590) 143474..143911 - 438 WP_002300851.1 hypothetical protein -
O4N81_RS14595 (O4N81_14595) 143926..144177 - 252 WP_002296238.1 hypothetical protein -
O4N81_RS14600 (O4N81_14600) 144177..144383 - 207 WP_002347218.1 hypothetical protein -
O4N81_RS14605 (O4N81_14605) 144820..145080 - 261 WP_002295623.1 hypothetical protein -
O4N81_RS14610 (O4N81_14610) 145254..145358 + 105 WP_008274030.1 putative holin-like toxin -
O4N81_RS14615 (O4N81_14615) 145499..145984 - 486 WP_002303313.1 single-stranded DNA-binding protein -
O4N81_RS14620 (O4N81_14620) 145987..146886 - 900 WP_002303312.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
O4N81_RS14625 (O4N81_14625) 146899..147492 - 594 WP_002303311.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
O4N81_RS14630 (O4N81_14630) 147568..147717 - 150 WP_002303309.1 hypothetical protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance