MGE detailed information
MGE type: Conjugative plasmid MGE length: 118453 bp
Accession: NZ_CP107434 Location: 1..118453 Organism: Klebsiella pneumoniae strain CRKP_18 Replicon: plasmid unnamed2
Accession: NZ_CP107434 Location: 1..118453 Organism: Klebsiella pneumoniae strain CRKP_18 Replicon: plasmid unnamed2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OH509_RS28105 (1) | 1..477 | + | 477 | WP_013023839.1 | WbuC family cupin fold metalloprotein | - |
| OH509_RS28110 (524) | 524..1399 | - | 876 | WP_015387340.1 | Beta-lactamase CTX-M-1 | ARG |
| OH509_RS28115 (1821) | 1821..2525 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| OH509_RS28120 (2591) | 2591..2656 | + | 66 | Protein_3 | IS1 family transposase | - |
| OH509_RS28125 (4105) | 4105..4339 | + | 235 | Protein_4 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| OH509_RS28130 (4467) | 4467..4748 | + | 282 | WP_001333089.1 | hypothetical protein | - |
| OH509_RS28135 (4871) | 4871..5221 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| OH509_RS28140 (5224) | 5224..6186 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| OH509_RS28145 (6333) | 6333..6626 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| OH509_RS28150 (6703) | 6703..7386 | + | 684 | WP_000085883.1 | DNA methylase | - |
| OH509_RS28155 (7387) | 7387..7608 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| OH509_RS28160 (7622) | 7622..8056 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| OH509_RS28165 (8107) | 8107..8883 | + | 777 | WP_001383963.1 | hypothetical protein | - |
| OH509_RS28170 (9301) | 9301..9726 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| OH509_RS28175 (9773) | 9773..10195 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| OH509_RS28180 (10192) | 10192..10383 | + | 192 | WP_001027493.1 | hypothetical protein | - |
| OH509_RS28185 (11421) | 11421..11651 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| OH509_RS28190 (11703) | 11703..13064 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| OH509_RS28195 (13111) | 13111..13674 | + | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| OH509_RS28200 (13760) | 13760..14215 | - | 456 | Protein_19 | hypothetical protein | - |
| OH509_RS28205 (14517) | 14517..15044 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| OH509_RS28210 (15102) | 15102..15335 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| OH509_RS28215 (15396) | 15396..17419 | + | 2024 | Protein_22 | ParB/RepB/Spo0J family partition protein | - |
| OH509_RS28220 (17488) | 17488..17922 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| OH509_RS28225 (17919) | 17919..18638 | + | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| - (18650) | 18650..18874 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (18650) | 18650..18874 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (18650) | 18650..18874 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (18650) | 18650..18874 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| OH509_RS28230 (18860) | 18860..19009 | + | 150 | Protein_25 | plasmid maintenance protein Mok | - |
| OH509_RS28235 (18951) | 18951..19076 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| OH509_RS28240 (19395) | 19395..19691 | - | 297 | Protein_27 | hypothetical protein | - |
| OH509_RS28245 (19991) | 19991..20287 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| OH509_RS28250 (20398) | 20398..21219 | + | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| OH509_RS28255 (21516) | 21516..22163 | - | 648 | WP_015059008.1 | hypothetical protein | VF |
| OH509_RS28260 (22440) | 22440..22823 | + | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| OH509_RS28265 (23014) | 23014..23700 | + | 687 | WP_015059009.1 | PAS domain-containing protein | - |
| OH509_RS28270 (23794) | 23794..24021 | + | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| OH509_RS28275 (24055) | 24055..24420 | + | 366 | WP_021519752.1 | type IV conjugative transfer system pilin TraA | - |
| OH509_RS28280 (24435) | 24435..24746 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| OH509_RS28285 (24768) | 24768..25334 | + | 567 | WP_000399794.1 | type IV conjugative transfer system protein TraE | - |
| OH509_RS28290 (25321) | 25321..26049 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| OH509_RS28295 (26049) | 26049..27476 | + | 1428 | WP_032297072.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| OH509_RS28300 (27466) | 27466..28056 | + | 591 | WP_000002778.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| OH509_RS28305 (28043) | 28043..28240 | + | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| OH509_RS28310 (28252) | 28252..28503 | + | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| OH509_RS28315 (28500) | 28500..29015 | + | 516 | WP_000809902.1 | type IV conjugative transfer system lipoprotein TraV | - |
| OH509_RS28320 (29150) | 29150..29371 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| OH509_RS28325 (29531) | 29531..32158 | + | 2628 | WP_015059012.1 | type IV secretion system protein TraC | - |
| OH509_RS28330 (32155) | 32155..32541 | + | 387 | WP_015059013.1 | type-F conjugative transfer system protein TrbI | - |
| OH509_RS28335 (32538) | 32538..33170 | + | 633 | WP_001203735.1 | type-F conjugative transfer system protein TraW | - |
| OH509_RS28340 (33167) | 33167..34159 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| OH509_RS28345 (34186) | 34186..34494 | + | 309 | WP_000412447.1 | hypothetical protein | - |
| OH509_RS28350 (34557) | 34557..35078 | + | 522 | WP_015059014.1 | hypothetical protein | - |
| OH509_RS28355 (35105) | 35105..35743 | + | 639 | WP_000087532.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| OH509_RS28360 (35740) | 35740..36111 | + | 372 | WP_000056336.1 | hypothetical protein | - |
| OH509_RS28365 (36137) | 36137..36559 | + | 423 | WP_001229309.1 | HNH endonuclease signature motif containing protein | - |
| OH509_RS28370 (36556) | 36556..38406 | + | 1851 | WP_015059015.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| OH509_RS28375 (38433) | 38433..38690 | + | 258 | WP_053913405.1 | conjugal transfer protein TrbE | - |
| OH509_RS28380 (38677) | 38677..39426 | + | 750 | WP_072354014.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| OH509_RS28385 (39587) | 39587..39823 | + | 237 | WP_000270010.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| OH509_RS28390 (39810) | 39810..40355 | + | 546 | WP_000059817.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| OH509_RS28395 (40345) | 40345..40659 | + | 315 | WP_001384255.1 | P-type conjugative transfer protein TrbJ | - |
| OH509_RS28400 (40613) | 40613..41005 | + | 393 | WP_000126338.1 | F-type conjugal transfer protein TrbF | - |
| OH509_RS28405 (40992) | 40992..42365 | + | 1374 | WP_000944325.1 | conjugal transfer pilus assembly protein TraH | - |
| OH509_RS28410 (42362) | 42362..45178 | + | 2817 | WP_015059018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| OH509_RS28415 (45211) | 45211..45732 | + | 522 | WP_000632668.1 | conjugal transfer entry exclusion protein TraS | - |
| OH509_RS28420 (45757) | 45757..46488 | + | 732 | WP_021559024.1 | conjugal transfer complement resistance protein TraT | - |
| OH509_RS28425 (46691) | 46691..47428 | + | 738 | WP_015059020.1 | hypothetical protein | - |
| OH509_RS28430 (47479) | 47479..49713 | + | 2235 | WP_032316743.1 | type IV conjugative transfer system coupling protein TraD | - |
| OH509_RS28435 (49713) | 49713..54983 | + | 5271 | WP_072648275.1 | Multifunctional conjugation protein TraI | Relaxase |
| OH509_RS28440 (55003) | 55003..55749 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| OH509_RS28445 (55804) | 55804..56364 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| OH509_RS28450 (56496) | 56496..56696 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| OH509_RS28455 (57082) | 57082..57681 | + | 600 | WP_032083981.1 | PIN domain-containing protein | - |
| OH509_RS28460 (57743) | 57743..58075 | + | 333 | WP_152916585.1 | hypothetical protein | - |
| - (58276) | 58276..58335 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (58276) | 58276..58335 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (58276) | 58276..58335 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (58276) | 58276..58335 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| OH509_RS28465 (58380) | 58380..58529 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| OH509_RS28470 (58813) | 58813..59061 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
| OH509_RS28475 (59306) | 59306..59380 | + | 75 | WP_001375168.1 | RepA leader peptide Tap | - |
| OH509_RS28480 (59373) | 59373..60230 | + | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| OH509_RS28485 (61169) | 61169..61822 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| OH509_RS28490 (61915) | 61915..62172 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| OH509_RS28495 (62105) | 62105..62506 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| OH509_RS28500 (62755) | 62755..63170 | + | 416 | Protein_79 | IS1-like element IS1B family transposase | - |
| OH509_RS28505 (63206) | 63206..63751 | - | 546 | Protein_80 | Tn3 family transposase TnpA_Tn3 | Transposase |
| OH509_RS28510 (63817) | 63817..64521 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| OH509_RS28515 (64586) | 64586..65266 | - | 681 | Protein_82 | IS91 family transposase ISAzo26 | Transposase |
| OH509_RS28520 (65538) | 65538..66242 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| OH509_RS28525 (66248) | 66248..66388 | + | 141 | WP_001044210.1 | hypothetical protein | - |
| OH509_RS28530 (66874) | 66874..67611 | + | 738 | WP_001446887.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| OH509_RS28535 (67608) | 67608..67832 | + | 225 | WP_000743213.1 | hypothetical protein | - |
| OH509_RS28540 (68043) | 68043..69536 | + | 1494 | WP_001120888.1 | IS91 family transposase ISVsa3 | Transposase |
| OH509_RS28545 (69567) | 69567..70451 | + | 885 | WP_021598067.1 | DUF3363 domain-containing protein | - |
| OH509_RS28550 (70668) | 70668..71882 | + | 1215 | WP_023300759.1 | Bicyclomycin resistance protein | ARG |
| OH509_RS28555 (71910) | 71910..72215 | + | 306 | WP_001255015.1 | HTH-type transcriptional regulator HdfR | VF |
| OH509_RS28560 (72327) | 72327..72515 | + | 189 | Protein_91 | IS91 family transposase | - |
| OH509_RS28565 (72482) | 72482..73681 | - | 1200 | WP_032153701.1 | Tetracycline resistance protein, class C | ARG |
| OH509_RS28570 (73787) | 73787..74437 | + | 651 | WP_001493764.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| OH509_RS28575 (74466) | 74466..74711 | - | 246 | WP_058914914.1 | hypothetical protein | - |
| OH509_RS28580 (75017) | 75017..75853 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| OH509_RS28585 (75853) | 75853..76656 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| OH509_RS28590 (76717) | 76717..77532 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| OH509_RS28595 (77862) | 77862..77948 | + | 87 | Protein_98 | Arm DNA-binding domain-containing protein | - |
| OH509_RS28600 (78220) | 78220..79224 | - | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| OH509_RS28605 (79303) | 79303..81069 | - | 1767 | Protein_100 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| OH509_RS28610 (81121) | 81121..81825 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| OH509_RS28615 (81891) | 81891..82061 | - | 171 | Protein_102 | IS6 family transposase IS15 | Transposase |
| OH509_RS28620 (82082) | 82082..82876 | - | 795 | WP_000572405.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| OH509_RS28625 (82905) | 82905..84335 | - | 1431 | Protein_104 | IS4 family transposase IS50R | Transposase |
| OH509_RS28630 (84455) | 84455..84643 | + | 189 | WP_000957857.1 | hypothetical protein | - |
| OH509_RS28635 (84653) | 84653..85852 | + | 1200 | Protein_106 | IS91 family transposase ISSbo1 | Transposase |
| OH509_RS28640 (86338) | 86338..86691 | - | 354 | WP_024129958.1 | DNA distortion polypeptide 3 | - |
| OH509_RS28645 (86828) | 86828..87274 | - | 447 | WP_001074384.1 | hypothetical protein | - |
| OH509_RS28650 (87278) | 87278..88120 | - | 843 | WP_000435064.1 | replication initiation protein | - |
| OH509_RS28655 (88141) | 88141..88980 | - | 840 | WP_024129959.1 | replication initiation protein | - |
| OH509_RS28660 (90193) | 90193..90444 | + | 252 | WP_000121743.1 | plasmid stabilization protein | Antitoxin Detail |
| OH509_RS28665 (90434) | 90434..90715 | + | 282 | WP_000220561.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| OH509_RS28670 (90954) | 90954..91046 | - | 93 | Protein_113 | IS6 family transposase | - |
| OH509_RS28675 (91212) | 91212..92411 | - | 1200 | Protein_114 | IS91 family transposase ISSbo1 | Transposase |
| OH509_RS28680 (92421) | 92421..92609 | - | 189 | WP_000957857.1 | hypothetical protein | - |
| OH509_RS28685 (92839) | 92839..92943 | + | 105 | WP_032409716.1 | hypothetical protein | - |
| OH509_RS28690 (93072) | 93072..93329 | + | 258 | WP_000764642.1 | hypothetical protein | - |
| OH509_RS28695 (93387) | 93387..94163 | - | 777 | WP_000015958.1 | site-specific integrase | - |
| OH509_RS28700 (94160) | 94160..94903 | - | 744 | WP_000129823.1 | hypothetical protein | - |
| OH509_RS28705 (94954) | 94954..95304 | - | 351 | WP_000493378.1 | hypothetical protein | - |
| OH509_RS28710 (95984) | 95984..96979 | + | 996 | WP_000246635.1 | hypothetical protein | - |
| OH509_RS28715 (96983) | 96983..97915 | + | 933 | WP_000991830.1 | S-4TM family putative pore-forming effector | - |
| OH509_RS28720 (98213) | 98213..99301 | + | 1089 | WP_000952231.1 | hypothetical protein | - |
| OH509_RS28725 (99303) | 99303..100172 | + | 870 | WP_000253407.1 | hypothetical protein | - |
| OH509_RS28730 (100229) | 100229..101794 | - | 1566 | WP_000741348.1 | AAA family ATPase | - |
| OH509_RS28735 (102102) | 102102..102332 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| OH509_RS28740 (102329) | 102329..102745 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| OH509_RS28745 (102907) | 102907..105045 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| OH509_RS28750 (105399) | 105399..105656 | + | 258 | WP_000343085.1 | hypothetical protein | - |
| OH509_RS28755 (105656) | 105656..106246 | + | 591 | WP_000194575.1 | hypothetical protein | - |
| OH509_RS28760 (106509) | 106509..108065 | + | 1557 | WP_024126035.1 | AAA family ATPase | - |
| OH509_RS28765 (108256) | 108256..108873 | + | 618 | WP_000521603.1 | ProQ/FINO family protein | - |
| OH509_RS28770 (109166) | 109166..110203 | - | 1038 | WP_044502555.1 | permease | - |
| OH509_RS28775 (110308) | 110308..110631 | + | 324 | WP_001175594.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| OH509_RS28780 (110830) | 110830..111534 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| OH509_RS28785 (111540) | 111540..112163 | + | 624 | WP_272043800.1 | replication initiation protein | - |
| OH509_RS28790 (112210) | 112210..112914 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| OH509_RS28795 (112966) | 112966..113379 | - | 414 | Protein_138 | serine hydrolase | - |
| OH509_RS28800 (113562) | 113562..114119 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| OH509_RS28805 (114424) | 114424..115128 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| OH509_RS28810 (115192) | 115192..115647 | + | 456 | Protein_141 | class A beta-lactamase | - |
| OH509_RS28815 (115817) | 115817..116572 | + | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| OH509_RS28820 (116698) | 116698..117402 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| OH509_RS28825 (117452) | 117452..118195 | + | 744 | Protein_144 | Beta-lactamase TEM | ARG |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|