MGE detailed information
MGE type: Conjugative plasmid MGE length: 111840 bp
Accession: NZ_CP104473 Location: 1..111840 Organism: Escherichia coli strain UC4224 Replicon: plasmid pUC4224_1
Accession: NZ_CP104473 Location: 1..111840 Organism: Escherichia coli strain UC4224 Replicon: plasmid pUC4224_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| N4S17_RS24580 (1) | 1..978 | + | 978 | WP_001369978.1 | RepB family plasmid replication initiator protein | - |
| N4S17_RS24585 (1217) | 1217..1499 | - | 283 | Protein_1 | ISL3 family transposase ISEc53 | Transposase |
| N4S17_RS24590 (1656) | 1656..1886 | - | 231 | WP_032279745.1 | hypothetical protein | - |
| N4S17_RS24595 (2016) | 2016..2339 | - | 324 | WP_231364795.1 | Transcriptional repressor MprA | VF |
| N4S17_RS24600 (2388) | 2388..2564 | - | 177 | Protein_4 | Transcriptional repressor MprA | VF |
| N4S17_RS24605 (2631) | 2631..4070 | - | 1440 | WP_001213534.1 | Hemolysin secretion protein D, chromosomal | VF |
| N4S17_RS24610 (4074) | 4074..6194 | - | 2121 | WP_072094473.1 | Alpha-hemolysin translocation ATP-binding protein HlyB | VF |
| N4S17_RS24615 (6244) | 6244..9240 | - | 2997 | WP_011310119.1 | Hemolysin, chromosomal | VF |
| N4S17_RS24620 (9242) | 9242..9757 | - | 516 | WP_001365635.1 | RTX-I toxin-activating lysine-acyltransferase ApxIC | VF |
| N4S17_RS24625 (10185) | 10185..10988 | - | 804 | WP_000899428.1 | Outer membrane protein A | VF |
| N4S17_RS24630 (11013) | 11013..15320 | - | 4308 | WP_099528466.1 | hypothetical protein | VF |
| N4S17_RS24635 (15541) | 15541..15825 | - | 285 | WP_000439678.1 | Major pilu subunit operon regulatory protein PapB | VF |
| N4S17_RS24640 (16432) | 16432..16979 | + | 548 | Protein_12 | transposase | - |
| N4S17_RS24645 (17309) | 17309..17743 | + | 435 | Protein_13 | IS110 family transposase ISEc21 | Transposase |
| N4S17_RS24650 (17830) | 17830..19367 | + | 1538 | Protein_14 | IS3 family transposase | - |
| N4S17_RS24655 (19472) | 19472..20101 | + | 630 | Protein_15 | transposase | - |
| N4S17_RS24660 (20121) | 20121..20469 | + | 349 | Protein_16 | integrase core domain-containing protein | - |
| N4S17_RS24665 (20834) | 20834..22390 | + | 1557 | WP_000554412.1 | L-lactate permease | - |
| N4S17_RS24670 (22441) | 22441..23160 | + | 720 | WP_001102093.1 | (Fe-S)-binding protein | - |
| N4S17_RS24675 (23171) | 23171..24586 | + | 1416 | WP_000054160.1 | LutB/LldF family L-lactate oxidation iron-sulfur protein | - |
| N4S17_RS24680 (24591) | 24591..25289 | + | 699 | WP_000431492.1 | lactate utilization protein C | - |
| N4S17_RS24685 (25330) | 25330..25566 | - | 237 | WP_001369996.1 | hypothetical protein | - |
| N4S17_RS24690 (25637) | 25637..26050 | - | 414 | Protein_22 | IS3 family transposase ISKpn8 | Transposase |
| N4S17_RS24695 (26214) | 26214..26525 | - | 312 | WP_000203483.1 | hypothetical protein | - |
| N4S17_RS24700 (26553) | 26553..26744 | - | 192 | WP_000264906.1 | hypothetical protein | - |
| N4S17_RS24705 (26754) | 26754..27119 | - | 366 | WP_028985519.1 | hypothetical protein | - |
| N4S17_RS24710 (27301) | 27301..27462 | + | 162 | WP_001365636.1 | hypothetical protein | - |
| N4S17_RS24715 (27625) | 27625..31527 | - | 3903 | WP_261306979.1 | Serine protease EspP | VF |
| N4S17_RS24720 (32024) | 32024..32410 | - | 387 | WP_099528467.1 | thermonuclease family protein | - |
| N4S17_RS24725 (32569) | 32569..33246 | + | 678 | WP_001158025.1 | hypothetical protein | - |
| N4S17_RS24730 (33736) | 33736..34056 | - | 321 | WP_000220092.1 | hypothetical protein | - |
| N4S17_RS24735 (34114) | 34114..35277 | - | 1164 | Protein_31 | IS3 family transposase ISEc17 | Transposase |
| N4S17_RS24740 (35687) | 35687..37069 | + | 1383 | WP_028985325.1 | hypothetical protein | VF |
| N4S17_RS24745 (37320) | 37320..37609 | + | 290 | Protein_33 | IS3 family transposase IS3F | Transposase |
| N4S17_RS24750 (37813) | 37813..37992 | + | 180 | Protein_34 | IS3 family transposase | - |
| N4S17_RS24755 (38300) | 38300..40387 | + | 2088 | WP_028985399.1 | bifunctional siderophore receptor/adhesin Iha | - |
| N4S17_RS24760 (40648) | 40648..41070 | - | 423 | WP_028985400.1 | Exc2 family lipoprotein | - |
| N4S17_RS24765 (41353) | 41353..41868 | + | 516 | Protein_37 | IS91 family transposase IS91 | Transposase |
| N4S17_RS24770 (42199) | 42199..42438 | - | 240 | WP_000859018.1 | winged helix-turn-helix transcriptional regulator | - |
| N4S17_RS24775 (43414) | 43414..44271 | - | 858 | WP_028985401.1 | incFII family plasmid replication initiator RepA | - |
| N4S17_RS24780 (44264) | 44264..44338 | - | 75 | WP_062865987.1 | RepA leader peptide Tap | - |
| N4S17_RS24785 (44574) | 44574..44831 | - | 258 | WP_000084404.1 | replication regulatory protein RepA | - |
| N4S17_RS24790 (45115) | 45115..45264 | - | 150 | WP_001336447.1 | Hok/Gef family protein | Toxin Detail |
| - (45308) | 45308..45369 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (45308) | 45308..45369 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (45308) | 45308..45369 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (45308) | 45308..45369 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| N4S17_RS24795 (45685) | 45685..45927 | - | 243 | WP_225303886.1 | hypothetical protein | - |
| N4S17_RS24800 (46030) | 46030..46489 | - | 460 | Protein_44 | thermonuclease family protein | - |
| N4S17_RS24805 (47232) | 47232..47435 | - | 204 | WP_032295436.1 | hypothetical protein | - |
| N4S17_RS24810 (47590) | 47590..48147 | - | 558 | WP_028985402.1 | fertility inhibition protein FinO | - |
| N4S17_RS24815 (48202) | 48202..48948 | - | 747 | WP_028985403.1 | conjugal transfer pilus acetylase TraX | - |
| N4S17_RS24820 (48968) | 48968..54238 | - | 5271 | WP_028985404.1 | Multifunctional conjugation protein TraI | Relaxase |
| N4S17_RS24825 (54238) | 54238..56625 | - | 2388 | WP_261306980.1 | hypothetical protein | VF |
| N4S17_RS24830 (56681) | 56681..57412 | - | 732 | WP_137538280.1 | hypothetical protein | - |
| N4S17_RS24835 (57683) | 57683..58375 | - | 693 | WP_198458802.1 | hypothetical protein | - |
| N4S17_RS24840 (58543) | 58543..58854 | + | 312 | WP_000522220.1 | heavy metal-binding domain-containing protein | - |
| N4S17_RS24845 (58857) | 58857..61676 | - | 2820 | WP_028985426.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| N4S17_RS24850 (61673) | 61673..63046 | - | 1374 | WP_000944332.1 | conjugal transfer pilus assembly protein TraH | - |
| N4S17_RS24855 (63033) | 63033..63425 | - | 393 | WP_000660704.1 | F-type conjugal transfer protein TrbF | - |
| N4S17_RS24860 (63406) | 63406..63753 | - | 348 | WP_071531747.1 | P-type conjugative transfer protein TrbJ | - |
| N4S17_RS24865 (63683) | 63683..64228 | - | 546 | WP_001457363.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| N4S17_RS24870 (64215) | 64215..64505 | - | 291 | WP_021521297.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| N4S17_RS24875 (64901) | 64901..65242 | - | 342 | WP_028985427.1 | conjugal transfer protein TrbA | - |
| N4S17_RS24880 (65256) | 65256..65999 | - | 744 | WP_137538282.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| N4S17_RS24885 (65992) | 65992..66249 | - | 258 | WP_000864354.1 | conjugal transfer protein TrbE | - |
| N4S17_RS24890 (66263) | 66263..68167 | - | 1905 | WP_050457559.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| N4S17_RS24895 (68261) | 68261..68641 | - | 381 | WP_028985429.1 | hypothetical protein | - |
| N4S17_RS24900 (68638) | 68638..69276 | - | 639 | WP_001562875.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| N4S17_RS24905 (69469) | 69469..69708 | + | 240 | WP_001066128.1 | hypothetical protein | - |
| N4S17_RS24910 (69705) | 69705..69884 | - | 180 | WP_032295480.1 | hypothetical protein | - |
| N4S17_RS24915 (69905) | 69905..70053 | - | 149 | Protein_67 | TraU family protein | - |
| N4S17_RS24920 (70057) | 70057..70503 | - | 447 | WP_001289131.1 | hypothetical protein | - |
| N4S17_RS24925 (71231) | 71231..71773 | - | 543 | WP_001365589.1 | hypothetical protein | - |
| N4S17_RS24930 (71787) | 71787..72779 | - | 993 | WP_000817328.1 | conjugal transfer pilus assembly protein TraU | - |
| N4S17_RS24935 (72776) | 72776..73408 | - | 633 | WP_044804161.1 | type-F conjugative transfer system protein TraW | - |
| N4S17_RS24940 (73405) | 73405..73791 | - | 387 | WP_028985434.1 | type-F conjugative transfer system protein TrbI | - |
| N4S17_RS24945 (73788) | 73788..76415 | - | 2628 | WP_028985435.1 | type IV secretion system protein TraC | - |
| N4S17_RS24950 (76575) | 76575..76796 | - | 222 | WP_001278980.1 | conjugal transfer protein TraR | - |
| N4S17_RS24955 (76931) | 76931..77446 | - | 516 | WP_099528473.1 | type IV conjugative transfer system lipoprotein TraV | - |
| N4S17_RS24960 (77443) | 77443..77694 | - | 252 | WP_001038336.1 | conjugal transfer protein TrbG | - |
| N4S17_RS24965 (77687) | 77687..78007 | - | 321 | WP_001057268.1 | DUF2689 domain-containing protein | - |
| N4S17_RS24970 (77994) | 77994..78581 | - | 588 | WP_000002895.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| N4S17_RS24975 (78571) | 78571..80001 | - | 1431 | WP_000146622.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| N4S17_RS24980 (80001) | 80001..80729 | - | 729 | WP_001385684.1 | type-F conjugative transfer system secretin TraK | - |
| N4S17_RS24985 (80716) | 80716..81282 | - | 567 | WP_000399758.1 | type IV conjugative transfer system protein TraE | - |
| N4S17_RS24990 (81304) | 81304..81615 | - | 312 | WP_000012120.1 | type IV conjugative transfer system protein TraL | - |
| N4S17_RS24995 (81630) | 81630..81983 | - | 354 | WP_021521309.1 | type IV conjugative transfer system pilin TraA | - |
| N4S17_RS25000 (82018) | 82018..82245 | - | 228 | WP_032142519.1 | conjugal transfer relaxosome protein TraY | - |
| N4S17_RS25005 (82333) | 82333..83022 | - | 690 | WP_028985437.1 | PAS domain-containing protein | - |
| N4S17_RS25010 (83214) | 83214..83597 | - | 384 | WP_021521311.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| N4S17_RS25015 (84051) | 84051..84530 | + | 480 | WP_249821647.1 | hypothetical protein | VF |
| N4S17_RS25020 (84826) | 84826..85647 | - | 822 | WP_028985438.1 | DUF932 domain-containing protein | - |
| N4S17_RS25025 (85765) | 85765..86052 | - | 288 | WP_000107526.1 | hypothetical protein | - |
| N4S17_RS25030 (86208) | 86208..86510 | - | 303 | WP_001272236.1 | hypothetical protein | - |
| N4S17_RS25035 (86810) | 86810..87107 | + | 298 | Protein_91 | hypothetical protein | - |
| N4S17_RS25040 (87408) | 87408..87530 | - | 123 | WP_223200913.1 | Hok/Gef family protein | Toxin Detail |
| N4S17_RS25045 (87475) | 87475..87627 | - | 153 | Protein_93 | DUF5431 family protein | - |
| - (87634) | 87634..87828 | - | 195 | NuclAT_0 | - | Antitoxin Detail |
| - (87634) | 87634..87828 | - | 195 | NuclAT_0 | - | Antitoxin Detail |
| - (87634) | 87634..87828 | - | 195 | NuclAT_0 | - | Antitoxin Detail |
| - (87634) | 87634..87828 | - | 195 | NuclAT_0 | - | Antitoxin Detail |
| N4S17_RS25050 (87777) | 87777..88091 | - | 315 | Protein_94 | theronine dehydrogenase | - |
| N4S17_RS25055 (88088) | 88088..88807 | - | 720 | WP_000116348.1 | plasmid SOS inhibition protein A | - |
| N4S17_RS25060 (88804) | 88804..89238 | - | 435 | WP_000845927.1 | conjugation system SOS inhibitor PsiB | - |
| N4S17_RS25065 (89293) | 89293..91251 | - | 1959 | WP_050864290.1 | ParB/RepB/Spo0J family partition protein | - |
| N4S17_RS25070 (91316) | 91316..91549 | - | 234 | WP_000005988.1 | DUF905 family protein | - |
| N4S17_RS25075 (91607) | 91607..92128 | - | 522 | WP_000290783.1 | single-stranded DNA-binding protein | - |
| N4S17_RS25080 (92430) | 92430..92985 | + | 556 | Protein_100 | hypothetical protein | - |
| N4S17_RS25085 (92966) | 92966..93529 | - | 564 | WP_001385677.1 | class I SAM-dependent methyltransferase | - |
| N4S17_RS25090 (93576) | 93576..94937 | - | 1362 | WP_028985386.1 | DUF3560 domain-containing protein | - |
| N4S17_RS25095 (94989) | 94989..95219 | - | 231 | WP_000218649.1 | hypothetical protein | - |
| N4S17_RS25100 (95734) | 95734..96205 | + | 472 | Protein_104 | hypothetical protein | - |
| N4S17_RS25105 (96184) | 96184..96375 | - | 192 | WP_001027048.1 | hypothetical protein | - |
| N4S17_RS25110 (96375) | 96375..96794 | - | 420 | WP_000271710.1 | DUF1380 family protein | - |
| N4S17_RS25115 (96841) | 96841..97266 | - | 426 | WP_099528462.1 | antirestriction protein | - |
| N4S17_RS25120 (97682) | 97682..98428 | - | 747 | WP_198406610.1 | hypothetical protein | - |
| N4S17_RS25125 (98411) | 98411..98809 | - | 399 | Protein_109 | DUF1380 domain-containing protein | - |
| N4S17_RS25130 (98823) | 98823..99044 | - | 222 | WP_001104895.1 | hypothetical protein | - |
| N4S17_RS25135 (99045) | 99045..99728 | - | 684 | WP_099528464.1 | DNA methylase | - |
| N4S17_RS25140 (99805) | 99805..100110 | - | 306 | WP_032236829.1 | hypothetical protein | - |
| N4S17_RS25145 (100114) | 100114..101016 | - | 903 | WP_077629773.1 | DUF1281 domain-containing protein | - |
| N4S17_RS25150 (101292) | 101292..101540 | + | 249 | WP_000618108.1 | DinI-like family protein | - |
| N4S17_RS25155 (101537) | 101537..101974 | + | 438 | WP_028985391.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| N4S17_RS25160 (101974) | 101974..103244 | + | 1271 | Protein_116 | translesion error-prone DNA polymerase V subunit UmuC | - |
| N4S17_RS25165 (103249) | 103249..103641 | - | 393 | WP_000340836.1 | plasmid partitioning/stability family protein | - |
| N4S17_RS25170 (103646) | 103646..104617 | - | 972 | WP_001103695.1 | plasmid segregation protein ParM | - |
| N4S17_RS25175 (104846) | 104846..105490 | + | 645 | WP_028985392.1 | AAA family ATPase | - |
| N4S17_RS25180 (105484) | 105484..105759 | + | 276 | WP_000239527.1 | hypothetical protein | - |
| N4S17_RS25185 (105897) | 105897..106706 | - | 810 | WP_000016958.1 | site-specific integrase | - |
| N4S17_RS25190 (106707) | 106707..107012 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| N4S17_RS25195 (107014) | 107014..107232 | - | 219 | WP_000813639.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| N4S17_RS25200 (107828) | 107828..108088 | + | 261 | WP_000343084.1 | hypothetical protein | - |
| N4S17_RS25205 (108085) | 108085..108675 | + | 591 | WP_198458803.1 | hypothetical protein | - |
| N4S17_RS25210 (108693) | 108693..109040 | - | 348 | WP_000142428.1 | DUF6404 family protein | - |
| N4S17_RS25215 (109294) | 109294..109503 | + | 210 | WP_225303885.1 | colicin E1 immunity protein | - |
| N4S17_RS25220 (109510) | 109510..109830 | - | 321 | WP_001365556.1 | colicin-like pore-forming protein | - |
| N4S17_RS25225 (109940) | 109940..110671 | - | 732 | WP_000850413.1 | conjugal transfer complement resistance protein TraT | - |
| N4S17_RS25230 (110948) | 110948..111100 | - | 153 | Protein_130 | IS481 family transposase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|