MGE detailed information

MGE type: Conjugative plasmid        MGE length: 161931 bp
Accession: NZ_CP104331        Location: 1..161931         Organism: Escherichia coli strain THB42-F3       Replicon: plasmid pHB42-F3


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0544_RS22365 (109) 109..357 + 249 WP_000083837.1 replication regulatory protein RepA -
N0544_RS22370 (472) 472..650 + 179 Protein_1 protein CopA/IncA -
N0544_RS22375 (669) 669..1526 + 858 WP_032495102.1 incFII family plasmid replication initiator RepA -
N0544_RS22380 (2440) 2440..2709 + 270 WP_089438644.1 type II toxin-antitoxin system antitoxin YacA -
N0544_RS22385 (2709) 2709..2987 + 279 Protein_4 type II toxin-antitoxin system toxin YacB -
N0544_RS22390 (3033) 3033..3713 + 681 WP_226156984.1 3'-5' exonuclease -
N0544_RS22395 (3759) 3759..4655 - 897 WP_226156987.1 hypothetical protein -
N0544_RS22400 (4797) 4797..5162 - 366 WP_226156990.1 hypothetical protein -
N0544_RS22405 (5477) 5477..6664 - 1188 WP_226156993.1 IS91 family transposase ISEc37 Transposase
N0544_RS22410 (6664) 6664..7029 - 366 WP_226156997.1 hypothetical protein -
N0544_RS22415 (7473) 7473..8701 + 1229 WP_162843061.1 IS3 family transposase IS2 Transposase
N0544_RS22420 (8861) 8861..13543 + 4683 WP_226156943.1 hypothetical protein VF
N0544_RS22425 (13956) 13956..14267 + 312 WP_259904982.1 hypothetical protein -
N0544_RS22430 (14795) 14795..18610 + 3816 WP_226156939.1 hypothetical protein -
N0544_RS22435 (18946) 18946..19694 + 749 Protein_14 ISKra4 family transposase ISEc51 Transposase
N0544_RS22440 (20055) 20055..20573 - 519 WP_259904984.1 DUF4238 domain-containing protein -
N0544_RS22445 (20880) 20880..21164 + 285 WP_075858633.1 ribbon-helix-helix protein, CopG family Antitoxin Detail
N0544_RS22450 (21164) 21164..21439 + 276 WP_226156935.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
N0544_RS22455 (21546) 21546..21749 + 204 Protein_18 hypothetical protein -
N0544_RS22460 (22046) 22046..22345 + 300 WP_226156930.1 hypothetical protein -
N0544_RS22470 (23174) 23174..26140 - 2967 WP_001138014.1 Tn3 family transposase TnpA_TnAs1 Transposase
N0544_RS22475 (26144) 26144..26704 - 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
N0544_RS22480 (26880) 26880..27230 - 351 WP_000454193.1 DUF3330 domain-containing protein -
N0544_RS22485 (27433) 27433..28446 - 1014 WP_104774822.1 IS91 family transposase ISAzo26 Transposase
N0544_RS22490 (28591) 28591..29088 + 498 WP_001083725.1 IS1595 family transposase ISSsu9 ARG
N0544_RS22495 (29200) 29200..29490 + 291 WP_001336345.1 DUF1010 domain-containing protein -
N0544_RS22500 (29496) 29496..30334 + 839 Protein_27 Streptomycin 3''-adenylyltransferase ARG
N0544_RS22505 (30451) 30451..30798 + 348 WP_000679427.1 Multidrug transporter EmrE ARG
N0544_RS22510 (30792) 30792..31124 + 333 Protein_29 IS6 family transposase IS15 Transposase
N0544_RS22515 (31181) 31181..31885 + 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
N0544_RS22520 (32014) 32014..32778 + 765 WP_001389365.1 IS6-like element IS6100 family transposase -
N0544_RS22525 (33271) 33271..33855 - 585 WP_001137892.1 macrolide-binding transcriptional repressor MphR(A) -
N0544_RS22530 (33855) 33855..35093 - 1239 WP_000004159.1 macrolide resistance MFS transporter Mrx(A) -
N0544_RS22535 (35090) 35090..35995 - 906 WP_000219391.1 hypothetical protein ARG
N0544_RS22540 (36117) 36117..36821 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
N0544_RS22545 (36886) 36886..37095 + 210 Protein_36 IS1 family transposase IS1X2 Transposase
N0544_RS22550 (38393) 38393..38572 + 180 WP_000347021.1 hypothetical protein -
N0544_RS22555 (38688) 38688..39332 - 645 WP_000203199.1 Tn3 family transposase TnpR_TnEc1 Transposase
N0544_RS22560 (39627) 39627..40247 + 621 WP_000864788.1 ParA family protein -
N0544_RS22565 (40299) 40299..40529 + 231 WP_000051066.1 plasmid partition protein ParG -
N0544_RS22570 (40953) 40953..42017 + 1065 WP_012291478.1 ParA family protein -
N0544_RS22575 (42555) 42555..42908 - 354 WP_024129958.1 DNA distortion polypeptide 3 -
N0544_RS22580 (43045) 43045..43491 - 447 WP_001074384.1 hypothetical protein -
N0544_RS22585 (43495) 43495..44337 - 843 WP_000435064.1 replication initiation protein -
N0544_RS22590 (44358) 44358..45197 - 840 WP_024129959.1 replication initiation protein -
N0544_RS22595 (46432) 46432..46683 + 252 WP_000121743.1 plasmid stabilization protein Antitoxin Detail
N0544_RS22600 (46673) 46673..46954 + 282 WP_000220561.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
N0544_RS22605 (47193) 47193..47285 - 93 Protein_48 IS6 family transposase -
N0544_RS22610 (47451) 47451..48650 - 1200 WP_000948429.1 IS91 family transposase ISSbo1 Transposase
N0544_RS22615 (48660) 48660..48848 - 189 WP_000957857.1 hypothetical protein -
N0544_RS22620 (48968) 48968..50398 + 1431 Protein_51 IS4 family transposase IS50R Transposase
N0544_RS22625 (50427) 50427..51221 + 795 WP_000572405.1 Aminoglycoside 3'-phosphotransferase ARG
N0544_RS22630 (51242) 51242..51478 + 237 Protein_53 hypothetical protein -
N0544_RS22635 (51528) 51528..52232 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
N0544_RS22640 (52178) 52178..52684 - 507 WP_250697724.1 replication initiation protein -
N0544_RS22645 (52690) 52690..53394 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
N0544_RS22650 (53593) 53593..53916 - 324 WP_001175594.1 metalloregulator ArsR/SmtB family transcription factor -
N0544_RS22655 (54021) 54021..55058 + 1038 WP_044502555.1 permease -
N0544_RS22660 (55351) 55351..55968 - 618 WP_000521603.1 ProQ/FINO family protein -
N0544_RS22665 (56160) 56160..57716 - 1557 WP_000818556.1 AAA family ATPase -
N0544_RS22670 (57979) 57979..58569 - 591 WP_000194575.1 hypothetical protein -
N0544_RS22675 (58569) 58569..58826 - 258 WP_000343085.1 hypothetical protein -
N0544_RS22680 (59180) 59180..61318 + 2139 WP_000350638.1 AAA family ATPase -
N0544_RS22685 (61480) 61480..61896 - 417 WP_001044768.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
N0544_RS22690 (61893) 61893..62123 - 231 WP_001261287.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
N0544_RS22695 (62419) 62419..62709 + 291 WP_000111771.1 hypothetical protein -
N0544_RS22700 (62699) 62699..63598 + 900 WP_000963206.1 nucleotide-binding protein -
N0544_RS22705 (63648) 63648..65873 - 2226 WP_000698737.1 P-loop NTPase fold protein -
N0544_RS22710 (65875) 65875..66963 - 1089 WP_000952217.1 transcriptional repressor PifC -
N0544_RS22715 (67506) 67506..67856 + 351 WP_000493378.1 hypothetical protein -
N0544_RS22720 (67907) 67907..68650 + 744 WP_000129823.1 hypothetical protein -
N0544_RS22725 (68647) 68647..69423 + 777 WP_000015958.1 site-specific integrase -
N0544_RS22730 (69481) 69481..69738 - 258 WP_000764642.1 hypothetical protein -
N0544_RS22735 (69867) 69867..69971 - 105 WP_032409716.1 hypothetical protein -
N0544_RS22740 (70501) 70501..71367 + 867 WP_004118283.1 replication initiation protein -
N0544_RS22745 (71544) 71544..71813 - 270 WP_000339857.1 hypothetical protein -
N0544_RS22750 (72228) 72228..73433 + 1206 WP_000368714.1 AAA family ATPase -
N0544_RS22755 (73433) 73433..74407 + 975 WP_000064119.1 ParB family protein -
N0544_RS22760 (74489) 74489..75760 - 1272 WP_001754953.1 Y-family DNA polymerase -
N0544_RS22765 (75760) 75760..76191 - 432 WP_000776034.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
N0544_RS22770 (76597) 76597..78084 + 1488 Protein_81 group II intron reverse transcriptase/maturase -
N0544_RS22775 (78236) 78236..78933 + 698 WP_223229472.1 IS1-like element IS1X3 family transposase -
N0544_RS22780 (78943) 78943..79251 + 309 Protein_83 replication initiation protein -
N0544_RS22785 (80654) 80654..81622 + 969 WP_030005799.1 IS5 family transposase IS903B Transposase
N0544_RS22790 (81762) 81762..82148 - 387 WP_001039464.1 plasmid stabilization protein StbA -
N0544_RS22795 (82730) 82730..82963 + 234 Protein_86 IS5 family transposase ISPan1 Transposase
N0544_RS22800 (82996) 82996..84510 - 1515 Protein_87 Tn3 family transposase TnpA_TnAs1 Transposase
N0544_RS22805 (84576) 84576..85280 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
N0544_RS22810 (85333) 85333..86088 + 756 Protein_89 IS110 family transposase IS5075 Transposase
N0544_RS22815 (86360) 86360..86446 - 87 Protein_90 Arm DNA-binding domain-containing protein -
N0544_RS22820 (86776) 86776..87591 + 816 WP_001043260.1 Dihydropteroate synthase ARG
N0544_RS22825 (87652) 87652..88455 + 804 WP_001082319.1 Aminoglycoside 3'-phosphotransferase ARG
N0544_RS22830 (88455) 88455..89291 + 837 WP_000480972.1 hypothetical protein ARG
N0544_RS22835 (89597) 89597..89839 + 243 WP_000844627.1 transposase -
N0544_RS22840 (89871) 89871..90521 - 651 WP_001493764.1 tetracycline resistance transcriptional repressor TetR(A) -
N0544_RS22845 (90627) 90627..91826 + 1200 WP_032153701.1 Tetracycline resistance protein, class C ARG
N0544_RS22850 (91793) 91793..91981 - 189 Protein_97 IS91 family transposase -
N0544_RS22855 (92093) 92093..92398 - 306 WP_001255015.1 HTH-type transcriptional regulator HdfR VF
N0544_RS22860 (92426) 92426..93640 - 1215 WP_023300759.1 Bicyclomycin resistance protein ARG
N0544_RS22865 (93857) 93857..94741 - 885 WP_021598067.1 DUF3363 domain-containing protein -
N0544_RS22870 (94772) 94772..96265 - 1494 WP_001120888.1 IS91 family transposase ISVsa3 Transposase
N0544_RS22875 (96476) 96476..96700 - 225 WP_000743213.1 hypothetical protein -
N0544_RS22880 (96697) 96697..97434 - 738 WP_001366550.1 Tn3 family transposase TnpR_TnEc1 Transposase
N0544_RS22885 (97846) 97846..98550 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
N0544_RS22890 (98861) 98861..99418 + 558 WP_001235713.1 Tn3 family transposase TnpR_Tn3 Transposase
N0544_RS22895 (99601) 99601..100461 + 861 WP_000027057.1 Beta-lactamase TEM ARG
N0544_RS22900 (100631) 100631..101386 + 756 WP_012372818.1 16S rRNA (guanine(1405)-N(7))-methyltransferase ARG
N0544_RS22905 (101512) 101512..102216 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
N0544_RS22910 (102266) 102266..103009 + 744 Protein_109 Beta-lactamase TEM ARG
N0544_RS22915 (103268) 103268..103744 + 477 WP_013023839.1 WbuC family cupin fold metalloprotein -
N0544_RS22920 (103791) 103791..104666 - 876 WP_015387340.1 Beta-lactamase CTX-M-1 ARG
N0544_RS22925 (105088) 105088..105792 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
N0544_RS22930 (107372) 107372..107606 + 235 Protein_113 type II toxin-antitoxin system RelE/ParE family toxin -
N0544_RS22935 (107734) 107734..107937 + 204 Protein_114 hypothetical protein -
N0544_RS22940 (108138) 108138..108488 - 351 WP_000361389.1 plasmid partitioning/stability family protein -
N0544_RS22945 (108491) 108491..109453 - 963 WP_000959884.1 plasmid segregation protein ParM -
N0544_RS22950 (109600) 109600..109893 + 294 WP_032146011.1 hypothetical protein -
N0544_RS22955 (109970) 109970..110653 + 684 WP_000085883.1 DNA methylase -
N0544_RS22960 (110654) 110654..110875 + 222 WP_001104881.1 hypothetical protein -
N0544_RS22965 (110889) 110889..111323 + 435 WP_000274503.1 DUF1380 family protein -
N0544_RS22970 (111374) 111374..112150 + 777 WP_001383963.1 hypothetical protein -
N0544_RS22975 (112568) 112568..112993 + 426 WP_001198928.1 antirestriction protein -
N0544_RS22980 (113040) 113040..113462 + 423 WP_000271762.1 DUF1380 family protein -
N0544_RS22985 (113459) 113459..113650 + 192 WP_001027493.1 hypothetical protein -
N0544_RS22990 (114688) 114688..114918 + 231 WP_000218642.1 hypothetical protein -
N0544_RS22995 (114970) 114970..116331 + 1362 WP_000170695.1 DUF3560 domain-containing protein -
N0544_RS23000 (116378) 116378..116941 + 564 WP_015059007.1 class I SAM-dependent methyltransferase -
N0544_RS23005 (117027) 117027..117488 - 462 Protein_128 hypothetical protein -
N0544_RS23010 (117790) 117790..118317 + 528 WP_000290834.1 single-stranded DNA-binding protein -
N0544_RS23015 (118375) 118375..118608 + 234 WP_000006003.1 DUF905 family protein -
N0544_RS23020 (118669) 118669..120637 + 1969 Protein_131 ParB/RepB/Spo0J family partition protein -
N0544_RS23025 (120706) 120706..121140 + 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
N0544_RS23030 (121137) 121137..121899 + 763 Protein_133 plasmid SOS inhibition protein A -
- (121868) 121868..122092 + 225 NuclAT_0 - -
- (121868) 121868..122092 + 225 NuclAT_0 - -
- (121868) 121868..122092 + 225 NuclAT_0 - -
- (121868) 121868..122092 + 225 NuclAT_0 - -
N0544_RS23035 (122078) 122078..122227 + 150 Protein_134 plasmid maintenance protein Mok -
N0544_RS23040 (122169) 122169..122294 + 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
N0544_RS23045 (122613) 122613..122909 - 297 Protein_136 hypothetical protein -
N0544_RS23050 (123209) 123209..123505 + 297 WP_001272251.1 hypothetical protein -
N0544_RS23055 (123616) 123616..124437 + 822 WP_001234445.1 DUF932 domain-containing protein -
N0544_RS23060 (124734) 124734..125381 - 648 WP_015059008.1 hypothetical protein VF
N0544_RS23065 (125658) 125658..126041 + 384 WP_000124981.1 conjugal transfer relaxosome DNA-binding protein TraM -
N0544_RS23070 (126232) 126232..126918 + 687 WP_015059009.1 PAS domain-containing protein -
N0544_RS23075 (127012) 127012..127239 + 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
N0544_RS23080 (127273) 127273..127638 + 366 WP_021519752.1 type IV conjugative transfer system pilin TraA -
N0544_RS23085 (127653) 127653..127964 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
N0544_RS23090 (127986) 127986..128552 + 567 WP_000399794.1 type IV conjugative transfer system protein TraE -
N0544_RS23095 (128539) 128539..129267 + 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
N0544_RS23100 (129267) 129267..130694 + 1428 WP_032297072.1 F-type conjugal transfer pilus assembly protein TraB -
N0544_RS23105 (130684) 130684..131274 + 591 WP_000002778.1 conjugal transfer pilus-stabilizing protein TraP -
N0544_RS23110 (131261) 131261..131458 + 198 WP_001324648.1 conjugal transfer protein TrbD -
N0544_RS23115 (131470) 131470..131721 + 252 WP_001038341.1 conjugal transfer protein TrbG -
N0544_RS23120 (131718) 131718..132233 + 516 WP_000809902.1 type IV conjugative transfer system lipoprotein TraV -
N0544_RS23125 (132368) 132368..132589 + 222 WP_001278692.1 conjugal transfer protein TraR -
N0544_RS23130 (132749) 132749..135376 + 2628 WP_015059012.1 type IV secretion system protein TraC -
N0544_RS23135 (135373) 135373..135759 + 387 WP_015059013.1 type-F conjugative transfer system protein TrbI -
N0544_RS23140 (135756) 135756..136388 + 633 WP_001203735.1 type-F conjugative transfer system protein TraW -
N0544_RS23145 (136385) 136385..137377 + 993 WP_259904979.1 conjugal transfer pilus assembly protein TraU -
N0544_RS23150 (137404) 137404..137712 + 309 WP_000412447.1 hypothetical protein -
N0544_RS23155 (137775) 137775..138296 + 522 WP_015059014.1 hypothetical protein -
N0544_RS23160 (138323) 138323..138961 + 639 WP_000087532.1 type-F conjugative transfer system pilin assembly protein TrbC -
N0544_RS23165 (138958) 138958..139329 + 372 WP_000056336.1 hypothetical protein -
N0544_RS23170 (139355) 139355..139777 + 423 WP_001229309.1 HNH endonuclease signature motif containing protein -
N0544_RS23175 (139774) 139774..141624 + 1851 WP_015059015.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
N0544_RS23180 (141651) 141651..141908 + 258 WP_000864321.1 conjugal transfer protein TrbE -
N0544_RS23185 (141901) 141901..142644 + 744 WP_001030371.1 type-F conjugative transfer system pilin assembly protein TraF -
N0544_RS23190 (142805) 142805..143041 + 237 WP_000270010.1 type-F conjugative transfer system pilin chaperone TraQ -
N0544_RS23195 (143028) 143028..143573 + 546 WP_000059817.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
N0544_RS23200 (143563) 143563..143877 + 315 WP_001384255.1 P-type conjugative transfer protein TrbJ -
N0544_RS23205 (143831) 143831..144223 + 393 WP_000126338.1 F-type conjugal transfer protein TrbF -
N0544_RS23210 (144210) 144210..145583 + 1374 WP_000944325.1 conjugal transfer pilus assembly protein TraH -
N0544_RS23215 (145580) 145580..148396 + 2817 WP_015059018.1 conjugal transfer mating-pair stabilization protein TraG -
N0544_RS23220 (148429) 148429..148950 + 522 WP_000632668.1 conjugal transfer entry exclusion protein TraS -
N0544_RS23225 (148975) 148975..149706 + 732 WP_021559024.1 conjugal transfer complement resistance protein TraT -
N0544_RS23230 (149909) 149909..150646 + 738 WP_015059020.1 hypothetical protein -
N0544_RS23235 (150697) 150697..152940 + 2244 WP_072646483.1 type IV conjugative transfer system coupling protein TraD -
N0544_RS23240 (152940) 152940..158210 + 5271 WP_061093447.1 Multifunctional conjugation protein TraI Relaxase
N0544_RS23245 (158230) 158230..158976 + 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
N0544_RS23250 (159031) 159031..159591 + 561 WP_000139328.1 fertility inhibition protein FinO -
N0544_RS23255 (159723) 159723..159923 + 201 WP_015059022.1 hypothetical protein -
N0544_RS23260 (160309) 160309..160908 + 600 WP_032083981.1 PIN domain-containing protein -
- (161503) 161503..161562 - 60 NuclAT_1 - -
- (161503) 161503..161562 - 60 NuclAT_1 - -
- (161503) 161503..161562 - 60 NuclAT_1 - -
- (161503) 161503..161562 - 60 NuclAT_1 - -
N0544_RS23265 (161607) 161607..161756 + 150 WP_001312851.1 Hok/Gef family protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance