NZ_CP1043271..162761

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 162761 bp
Accession: NZ_CP104327        Location: 1..162761         Organism: Escherichia coli strain THB42-F1       Replicon: plasmid pHB42-F1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0470_RS22580 () 109..357 + 249 WP_000083837.1 replication regulatory protein RepA -
N0470_RS22585 () 472..650 + 179 Protein_1 protein CopA/IncA -
N0470_RS22590 () 669..1526 + 858 WP_032495102.1 incFII family plasmid replication initiator RepA -
N0470_RS22595 () 2440..2709 + 270 WP_089438644.1 type II toxin-antitoxin system antitoxin YacA -
N0470_RS22600 () 2709..2987 + 279 Protein_4 type II toxin-antitoxin system toxin YacB -
N0470_RS22605 () 3033..3713 + 681 WP_226156984.1 3'-5' exonuclease -
N0470_RS22610 () 3759..4655 - 897 WP_226156987.1 hypothetical protein -
N0470_RS22615 () 4797..5162 - 366 WP_226156990.1 hypothetical protein -
N0470_RS22620 () 5477..6664 - 1188 WP_226156993.1 IS91 family transposase ISEc37 Transposase
N0470_RS22625 () 6664..7029 - 366 WP_226156997.1 hypothetical protein -
N0470_RS22630 () 7473..8701 + 1229 WP_162843061.1 IS3 family transposase IS2 Transposase
N0470_RS22635 () 8861..13543 + 4683 WP_226156943.1 hypothetical protein VF
N0470_RS22640 () 13971..14267 + 297 WP_226156941.1 hypothetical protein -
N0470_RS22645 () 14795..18610 + 3816 WP_226156939.1 hypothetical protein -
N0470_RS22650 () 18946..19694 + 749 Protein_14 ISKra4 family transposase ISEc51 Transposase
N0470_RS22655 () 20055..20573 - 519 WP_259904984.1 DUF4238 domain-containing protein -
N0470_RS22660 () 20880..21164 + 285 WP_075858633.1 ribbon-helix-helix protein, CopG family Antitoxin Detail
N0470_RS22665 () 21164..21439 + 276 WP_226156935.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
N0470_RS22670 () 21546..21749 + 204 Protein_18 hypothetical protein -
N0470_RS22675 () 22046..22345 + 300 WP_226156930.1 hypothetical protein -
N0470_RS22685 () 23174..26140 - 2967 WP_001138014.1 Tn3 family transposase TnpA_TnAs1 Transposase
N0470_RS22690 () 26144..26704 - 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
N0470_RS22695 () 26880..27230 - 351 WP_000454193.1 DUF3330 domain-containing protein -
N0470_RS22700 () 27433..28446 - 1014 WP_104774822.1 IS91 family transposase ISAzo26 Transposase
N0470_RS22705 () 28591..29088 + 498 WP_001083725.1 IS1595 family transposase ISSsu9 ARG
N0470_RS22710 () 29200..29490 + 291 WP_001336345.1 DUF1010 domain-containing protein -
N0470_RS22715 () 29496..30334 + 839 Protein_27 Streptomycin 3''-adenylyltransferase ARG
N0470_RS22720 () 30451..30798 + 348 WP_000679427.1 Multidrug transporter EmrE ARG
N0470_RS22725 () 30792..31124 + 333 Protein_29 IS6 family transposase IS15 Transposase
N0470_RS22730 () 31181..31884 + 704 Protein_30 IS6 family transposase IS26 Transposase
N0470_RS22735 () 32013..32777 + 765 WP_001389365.1 IS6-like element IS6100 family transposase -
N0470_RS22740 () 33270..33854 - 585 WP_001137892.1 macrolide-binding transcriptional repressor MphR(A) -
N0470_RS22745 () 33854..35092 - 1239 WP_000004159.1 macrolide resistance MFS transporter Mrx(A) -
N0470_RS22750 () 35089..35994 - 906 WP_000219391.1 hypothetical protein ARG
N0470_RS22755 () 36116..36820 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
N0470_RS22760 () 37131..37688 + 558 WP_001235713.1 Tn3 family transposase TnpR_Tn3 Transposase
N0470_RS22765 () 37871..38731 + 861 WP_000027057.1 Beta-lactamase TEM ARG
N0470_RS22770 () 38803..39507 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
N0470_RS22775 () 39572..39781 + 210 Protein_39 IS1 family transposase IS1X2 Transposase
N0470_RS22780 () 41079..41258 + 180 WP_000347021.1 hypothetical protein -
N0470_RS22785 () 41374..42018 - 645 WP_000203199.1 Tn3 family transposase TnpR_TnEc1 Transposase
N0470_RS22790 () 42313..42933 + 621 WP_000864788.1 ParA family protein -
N0470_RS22795 () 42985..43215 + 231 WP_000051066.1 plasmid partition protein ParG -
N0470_RS22800 () 43639..44703 + 1065 WP_012291478.1 ParA family protein -
N0470_RS22805 () 45241..45594 - 354 WP_024129958.1 DNA distortion polypeptide 3 -
N0470_RS22810 () 45731..46177 - 447 WP_001074384.1 hypothetical protein -
N0470_RS22815 () 46181..47023 - 843 WP_000435064.1 replication initiation protein -
N0470_RS22820 () 47044..47883 - 840 WP_024129959.1 replication initiation protein -
N0470_RS22825 () 49118..49369 + 252 WP_000121743.1 plasmid stabilization protein Antitoxin Detail
N0470_RS22830 () 49359..49640 + 282 WP_000220561.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
N0470_RS22835 () 49879..49971 - 93 Protein_51 IS6 family transposase -
N0470_RS22840 () 50137..51336 - 1200 WP_000948429.1 IS91 family transposase ISSbo1 Transposase
N0470_RS22845 () 51346..51534 - 189 WP_000957857.1 hypothetical protein -
N0470_RS22850 () 51654..53084 + 1431 Protein_54 IS4 family transposase IS50R Transposase
N0470_RS22855 () 53113..53907 + 795 WP_000572405.1 Aminoglycoside 3'-phosphotransferase ARG
N0470_RS22860 () 53928..54164 + 237 Protein_56 hypothetical protein -
N0470_RS22865 () 54214..54919 + 706 Protein_57 IS6 family transposase IS15DI Transposase
N0470_RS22870 () 54865..55371 - 507 WP_250697724.1 replication initiation protein -
N0470_RS22875 () 55377..56083 - 707 Protein_59 IS6 family transposase IS15DI Transposase
N0470_RS22880 () 56282..56605 - 324 WP_001175594.1 metalloregulator ArsR/SmtB family transcription factor -
N0470_RS22885 () 56710..57747 + 1038 WP_044502555.1 permease -
N0470_RS22890 () 58040..58657 - 618 WP_000521603.1 ProQ/FINO family protein -
N0470_RS22895 () 58849..60405 - 1557 WP_000818556.1 AAA family ATPase -
N0470_RS22900 () 60668..61258 - 591 WP_000194575.1 hypothetical protein -
N0470_RS22905 () 61258..61515 - 258 WP_000343085.1 hypothetical protein -
N0470_RS22910 () 61869..64007 + 2139 WP_000350638.1 AAA family ATPase -
N0470_RS22915 () 64169..64585 - 417 WP_001044768.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
N0470_RS22920 () 64582..64812 - 231 WP_001261287.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
N0470_RS22925 () 65108..65398 + 291 WP_000111771.1 hypothetical protein -
N0470_RS22930 () 65388..66287 + 900 WP_000963206.1 nucleotide-binding protein -
N0470_RS22935 () 66337..68562 - 2226 WP_000698737.1 P-loop NTPase fold protein -
N0470_RS22940 () 68564..69652 - 1089 WP_000952217.1 transcriptional repressor PifC -
N0470_RS22945 () 70195..70545 + 351 WP_000493378.1 hypothetical protein -
N0470_RS22950 () 70596..71339 + 744 WP_000129823.1 hypothetical protein -
N0470_RS22955 () 71336..72112 + 777 WP_000015958.1 site-specific integrase -
N0470_RS22960 () 72170..72427 - 258 WP_000764642.1 hypothetical protein -
N0470_RS22965 () 72556..72660 - 105 WP_032409716.1 hypothetical protein -
N0470_RS22970 () 73190..74056 + 867 WP_004118283.1 replication initiation protein -
N0470_RS22975 () 74233..74502 - 270 WP_000339857.1 hypothetical protein -
N0470_RS22980 () 74917..76122 + 1206 WP_000368714.1 AAA family ATPase -
N0470_RS22985 () 76122..77096 + 975 WP_000064119.1 ParB family protein -
N0470_RS22990 () 77178..78449 - 1272 WP_001754953.1 Y-family DNA polymerase -
N0470_RS22995 () 78449..78880 - 432 WP_000776034.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
N0470_RS23000 () 79286..80773 + 1488 Protein_84 group II intron reverse transcriptase/maturase -
N0470_RS23005 () 80925..81622 + 698 WP_223229472.1 IS1 family transposase IS1X3 Transposase
N0470_RS23010 () 81632..81940 + 309 Protein_86 replication initiation protein -
N0470_RS23015 () 83343..84311 + 969 WP_030005799.1 IS5 family transposase IS903B Transposase
N0470_RS23020 () 84451..84837 - 387 WP_001039464.1 plasmid stabilization protein StbA -
N0470_RS23025 () 85419..85652 + 234 Protein_89 IS5 family transposase ISPan1 Transposase
N0470_RS23030 () 85685..87199 - 1515 Protein_90 Tn3 family transposase TnpA_TnAs1 Transposase
N0470_RS23035 () 87265..87969 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
N0470_RS23040 () 88022..88777 + 756 Protein_92 IS110 family transposase IS5075 Transposase
N0470_RS23045 () 89049..89135 - 87 Protein_93 Arm DNA-binding domain-containing protein -
N0470_RS23050 () 89465..90280 + 816 WP_001043260.1 Dihydropteroate synthase ARG
N0470_RS23055 () 90341..91144 + 804 WP_001082319.1 Aminoglycoside 3'-phosphotransferase ARG
N0470_RS23060 () 91144..91980 + 837 WP_000480972.1 hypothetical protein ARG
N0470_RS23065 () 92286..92528 + 243 WP_000844627.1 transposase -
N0470_RS23070 () 92560..93210 - 651 WP_001493764.1 tetracycline resistance transcriptional repressor TetR(A) -
N0470_RS23075 () 93316..94515 + 1200 WP_032153701.1 Tetracycline resistance protein, class C ARG
N0470_RS23080 () 94482..94670 - 189 Protein_100 IS91 family transposase -
N0470_RS23085 () 94782..95087 - 306 WP_001255015.1 HTH-type transcriptional regulator HdfR VF
N0470_RS23090 () 95115..96329 - 1215 WP_023300759.1 Bicyclomycin resistance protein ARG
N0470_RS23095 () 96546..97430 - 885 WP_021598067.1 DUF3363 domain-containing protein -
N0470_RS23100 () 97461..98954 - 1494 WP_001120888.1 IS91 family transposase ISVsa3 Transposase
N0470_RS23105 () 99165..99389 - 225 WP_000743213.1 hypothetical protein -
N0470_RS23110 () 99386..100123 - 738 WP_001366550.1 Tn3 family transposase TnpR_TnEc1 Transposase
N0470_RS23115 () 100535..101239 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
N0470_RS23120 () 101461..102216 + 756 WP_012372818.1 16S rRNA (guanine(1405)-N(7))-methyltransferase ARG
N0470_RS23125 () 102342..103046 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
N0470_RS23130 () 103096..103839 + 744 Protein_110 Beta-lactamase TEM ARG
N0470_RS23135 () 104098..104574 + 477 WP_013023839.1 WbuC family cupin fold metalloprotein -
N0470_RS23140 () 104621..105496 - 876 WP_015387340.1 Beta-lactamase CTX-M-1 ARG
N0470_RS23145 () 105918..106622 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
N0470_RS23150 () 108202..108436 + 235 Protein_114 type II toxin-antitoxin system RelE/ParE family toxin -
N0470_RS23155 () 108564..108767 + 204 Protein_115 hypothetical protein -
N0470_RS23160 () 108968..109318 - 351 WP_000361389.1 plasmid partitioning/stability family protein -
N0470_RS23165 () 109321..110283 - 963 WP_000959884.1 plasmid segregation protein ParM -
N0470_RS23170 () 110430..110723 + 294 WP_032146011.1 hypothetical protein -
N0470_RS23175 () 110800..111483 + 684 WP_000085883.1 DNA methylase -
N0470_RS23180 () 111484..111705 + 222 WP_001104881.1 hypothetical protein -
N0470_RS23185 () 111719..112153 + 435 WP_000274503.1 DUF1380 family protein -
N0470_RS23190 () 112204..112980 + 777 WP_001383963.1 hypothetical protein -
N0470_RS23195 () 113398..113823 + 426 WP_001198928.1 antirestriction protein -
N0470_RS23200 () 113870..114292 + 423 WP_000271762.1 DUF1380 family protein -
N0470_RS23205 () 114289..114480 + 192 WP_001027493.1 hypothetical protein -
N0470_RS23210 () 115518..115748 + 231 WP_000218642.1 hypothetical protein -
N0470_RS23215 () 115800..117161 + 1362 WP_000170695.1 DUF3560 domain-containing protein -
N0470_RS23220 () 117208..117771 + 564 WP_015059007.1 class I SAM-dependent methyltransferase -
N0470_RS23225 () 117857..118318 - 462 Protein_129 hypothetical protein -
N0470_RS23230 () 118620..119147 + 528 WP_000290834.1 single-stranded DNA-binding protein -
N0470_RS23235 () 119205..119438 + 234 WP_000006003.1 DUF905 family protein -
N0470_RS23240 () 119499..121467 + 1969 Protein_132 ParB/RepB/Spo0J family partition protein -
N0470_RS23245 () 121536..121970 + 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
N0470_RS23250 () 121967..122729 + 763 Protein_134 plasmid SOS inhibition protein A -
- () 122698..122922 + 225 NuclAT_0 - -
- () 122698..122922 + 225 NuclAT_0 - -
- () 122698..122922 + 225 NuclAT_0 - -
- () 122698..122922 + 225 NuclAT_0 - -
N0470_RS23255 () 122707..122886 - 180 WP_001309233.1 hypothetical protein -
- 122855..122920 - 66 - - Antitoxin Detail
N0470_RS23260 () 122908..123057 + 150 Protein_136 plasmid maintenance protein Mok -
N0470_RS23265 () 122999..123124 + 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
N0470_RS23270 () 123443..123739 - 297 Protein_138 hypothetical protein -
N0470_RS23275 () 124039..124335 + 297 WP_001272251.1 hypothetical protein -
N0470_RS23280 () 124446..125267 + 822 WP_001234445.1 DUF932 domain-containing protein -
N0470_RS23285 () 125564..126211 - 648 WP_015059008.1 hypothetical protein VF
N0470_RS23290 () 126488..126871 + 384 WP_000124981.1 conjugal transfer relaxosome DNA-binding protein TraM -
N0470_RS23295 () 127062..127748 + 687 WP_015059009.1 PAS domain-containing protein -
N0470_RS23300 () 127842..128069 + 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
N0470_RS23305 () 128103..128468 + 366 WP_021519752.1 type IV conjugative transfer system pilin TraA -
N0470_RS23310 () 128483..128794 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
N0470_RS23315 () 128816..129382 + 567 WP_000399794.1 type IV conjugative transfer system protein TraE -
N0470_RS23320 () 129369..130097 + 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
N0470_RS23325 () 130097..131524 + 1428 WP_032297072.1 F-type conjugal transfer pilus assembly protein TraB -
N0470_RS23330 () 131514..132104 + 591 WP_000002778.1 conjugal transfer pilus-stabilizing protein TraP -
N0470_RS23335 () 132091..132288 + 198 WP_001324648.1 conjugal transfer protein TrbD -
N0470_RS23340 () 132300..132551 + 252 WP_001038341.1 conjugal transfer protein TrbG -
N0470_RS23345 () 132548..133063 + 516 WP_000809902.1 type IV conjugative transfer system lipoprotein TraV -
N0470_RS23350 () 133198..133419 + 222 WP_001278692.1 conjugal transfer protein TraR -
N0470_RS23355 () 133579..136206 + 2628 WP_015059012.1 type IV secretion system protein TraC -
N0470_RS23360 () 136203..136589 + 387 WP_015059013.1 type-F conjugative transfer system protein TrbI -
N0470_RS23365 () 136586..137218 + 633 WP_001203735.1 type-F conjugative transfer system protein TraW -
N0470_RS23370 () 137215..138207 + 993 WP_259904979.1 conjugal transfer pilus assembly protein TraU -
N0470_RS23375 () 138234..138542 + 309 WP_000412447.1 hypothetical protein -
N0470_RS23380 () 138605..139126 + 522 WP_015059014.1 hypothetical protein -
N0470_RS23385 () 139153..139791 + 639 WP_000087532.1 type-F conjugative transfer system pilin assembly protein TrbC -
N0470_RS23390 () 139788..140159 + 372 WP_000056336.1 hypothetical protein -
N0470_RS23395 () 140185..140607 + 423 WP_001229309.1 HNH endonuclease signature motif containing protein -
N0470_RS23400 () 140604..142454 + 1851 WP_015059015.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
N0470_RS23405 () 142481..142738 + 258 WP_000864321.1 conjugal transfer protein TrbE -
N0470_RS23410 () 142731..143474 + 744 WP_001030371.1 type-F conjugative transfer system pilin assembly protein TraF -
N0470_RS23415 () 143635..143871 + 237 WP_000270010.1 type-F conjugative transfer system pilin chaperone TraQ -
N0470_RS23420 () 143858..144403 + 546 WP_000059817.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
N0470_RS23425 () 144393..144707 + 315 WP_001384255.1 P-type conjugative transfer protein TrbJ -
N0470_RS23430 () 144661..145053 + 393 WP_000126338.1 F-type conjugal transfer protein TrbF -
N0470_RS23435 () 145040..146413 + 1374 WP_000944325.1 conjugal transfer pilus assembly protein TraH -
N0470_RS23440 () 146410..149226 + 2817 WP_015059018.1 conjugal transfer mating-pair stabilization protein TraG -
N0470_RS23445 () 149259..149780 + 522 WP_000632668.1 conjugal transfer entry exclusion protein TraS -
N0470_RS23450 () 149805..150536 + 732 WP_021559024.1 conjugal transfer complement resistance protein TraT -
N0470_RS23455 () 150739..151476 + 738 WP_015059020.1 hypothetical protein -
N0470_RS23460 () 151527..153770 + 2244 WP_072646483.1 type IV conjugative transfer system coupling protein TraD -
N0470_RS23465 () 153770..159040 + 5271 WP_061093447.1 Multifunctional conjugation protein TraI Relaxase
N0470_RS23470 () 159060..159806 + 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
N0470_RS23475 () 159861..160421 + 561 WP_000139328.1 fertility inhibition protein FinO -
N0470_RS23480 () 160553..160753 + 201 WP_015059022.1 hypothetical protein -
N0470_RS23485 () 161139..161738 + 600 WP_032083981.1 PIN domain-containing protein -
- () 162333..162392 - 60 NuclAT_1 - -
- () 162333..162392 - 60 NuclAT_1 - -
- () 162333..162392 - 60 NuclAT_1 - -
- () 162333..162392 - 60 NuclAT_1 - -
N0470_RS23490 () 162437..162586 + 150 WP_001312851.1 Hok/Gef family protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance