MGE detailed information
MGE type: Conjugative plasmid MGE length: 162761 bp
Accession: NZ_CP104327 Location: 1..162761 Organism: Escherichia coli strain THB42-F1 Replicon: plasmid pHB42-F1
Accession: NZ_CP104327 Location: 1..162761 Organism: Escherichia coli strain THB42-F1 Replicon: plasmid pHB42-F1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
N0470_RS22580 () | 109..357 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
N0470_RS22585 () | 472..650 | + | 179 | Protein_1 | protein CopA/IncA | - |
N0470_RS22590 () | 669..1526 | + | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
N0470_RS22595 () | 2440..2709 | + | 270 | WP_089438644.1 | type II toxin-antitoxin system antitoxin YacA | - |
N0470_RS22600 () | 2709..2987 | + | 279 | Protein_4 | type II toxin-antitoxin system toxin YacB | - |
N0470_RS22605 () | 3033..3713 | + | 681 | WP_226156984.1 | 3'-5' exonuclease | - |
N0470_RS22610 () | 3759..4655 | - | 897 | WP_226156987.1 | hypothetical protein | - |
N0470_RS22615 () | 4797..5162 | - | 366 | WP_226156990.1 | hypothetical protein | - |
N0470_RS22620 () | 5477..6664 | - | 1188 | WP_226156993.1 | IS91 family transposase ISEc37 | Transposase |
N0470_RS22625 () | 6664..7029 | - | 366 | WP_226156997.1 | hypothetical protein | - |
N0470_RS22630 () | 7473..8701 | + | 1229 | WP_162843061.1 | IS3 family transposase IS2 | Transposase |
N0470_RS22635 () | 8861..13543 | + | 4683 | WP_226156943.1 | hypothetical protein | VF |
N0470_RS22640 () | 13971..14267 | + | 297 | WP_226156941.1 | hypothetical protein | - |
N0470_RS22645 () | 14795..18610 | + | 3816 | WP_226156939.1 | hypothetical protein | - |
N0470_RS22650 () | 18946..19694 | + | 749 | Protein_14 | ISKra4 family transposase ISEc51 | Transposase |
N0470_RS22655 () | 20055..20573 | - | 519 | WP_259904984.1 | DUF4238 domain-containing protein | - |
N0470_RS22660 () | 20880..21164 | + | 285 | WP_075858633.1 | ribbon-helix-helix protein, CopG family | Antitoxin Detail |
N0470_RS22665 () | 21164..21439 | + | 276 | WP_226156935.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
N0470_RS22670 () | 21546..21749 | + | 204 | Protein_18 | hypothetical protein | - |
N0470_RS22675 () | 22046..22345 | + | 300 | WP_226156930.1 | hypothetical protein | - |
N0470_RS22685 () | 23174..26140 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
N0470_RS22690 () | 26144..26704 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
N0470_RS22695 () | 26880..27230 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
N0470_RS22700 () | 27433..28446 | - | 1014 | WP_104774822.1 | IS91 family transposase ISAzo26 | Transposase |
N0470_RS22705 () | 28591..29088 | + | 498 | WP_001083725.1 | IS1595 family transposase ISSsu9 | ARG |
N0470_RS22710 () | 29200..29490 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
N0470_RS22715 () | 29496..30334 | + | 839 | Protein_27 | Streptomycin 3''-adenylyltransferase | ARG |
N0470_RS22720 () | 30451..30798 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
N0470_RS22725 () | 30792..31124 | + | 333 | Protein_29 | IS6 family transposase IS15 | Transposase |
N0470_RS22730 () | 31181..31884 | + | 704 | Protein_30 | IS6 family transposase IS26 | Transposase |
N0470_RS22735 () | 32013..32777 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
N0470_RS22740 () | 33270..33854 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
N0470_RS22745 () | 33854..35092 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
N0470_RS22750 () | 35089..35994 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
N0470_RS22755 () | 36116..36820 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
N0470_RS22760 () | 37131..37688 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
N0470_RS22765 () | 37871..38731 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
N0470_RS22770 () | 38803..39507 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
N0470_RS22775 () | 39572..39781 | + | 210 | Protein_39 | IS1 family transposase IS1X2 | Transposase |
N0470_RS22780 () | 41079..41258 | + | 180 | WP_000347021.1 | hypothetical protein | - |
N0470_RS22785 () | 41374..42018 | - | 645 | WP_000203199.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
N0470_RS22790 () | 42313..42933 | + | 621 | WP_000864788.1 | ParA family protein | - |
N0470_RS22795 () | 42985..43215 | + | 231 | WP_000051066.1 | plasmid partition protein ParG | - |
N0470_RS22800 () | 43639..44703 | + | 1065 | WP_012291478.1 | ParA family protein | - |
N0470_RS22805 () | 45241..45594 | - | 354 | WP_024129958.1 | DNA distortion polypeptide 3 | - |
N0470_RS22810 () | 45731..46177 | - | 447 | WP_001074384.1 | hypothetical protein | - |
N0470_RS22815 () | 46181..47023 | - | 843 | WP_000435064.1 | replication initiation protein | - |
N0470_RS22820 () | 47044..47883 | - | 840 | WP_024129959.1 | replication initiation protein | - |
N0470_RS22825 () | 49118..49369 | + | 252 | WP_000121743.1 | plasmid stabilization protein | Antitoxin Detail |
N0470_RS22830 () | 49359..49640 | + | 282 | WP_000220561.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
N0470_RS22835 () | 49879..49971 | - | 93 | Protein_51 | IS6 family transposase | - |
N0470_RS22840 () | 50137..51336 | - | 1200 | WP_000948429.1 | IS91 family transposase ISSbo1 | Transposase |
N0470_RS22845 () | 51346..51534 | - | 189 | WP_000957857.1 | hypothetical protein | - |
N0470_RS22850 () | 51654..53084 | + | 1431 | Protein_54 | IS4 family transposase IS50R | Transposase |
N0470_RS22855 () | 53113..53907 | + | 795 | WP_000572405.1 | Aminoglycoside 3'-phosphotransferase | ARG |
N0470_RS22860 () | 53928..54164 | + | 237 | Protein_56 | hypothetical protein | - |
N0470_RS22865 () | 54214..54919 | + | 706 | Protein_57 | IS6 family transposase IS15DI | Transposase |
N0470_RS22870 () | 54865..55371 | - | 507 | WP_250697724.1 | replication initiation protein | - |
N0470_RS22875 () | 55377..56083 | - | 707 | Protein_59 | IS6 family transposase IS15DI | Transposase |
N0470_RS22880 () | 56282..56605 | - | 324 | WP_001175594.1 | metalloregulator ArsR/SmtB family transcription factor | - |
N0470_RS22885 () | 56710..57747 | + | 1038 | WP_044502555.1 | permease | - |
N0470_RS22890 () | 58040..58657 | - | 618 | WP_000521603.1 | ProQ/FINO family protein | - |
N0470_RS22895 () | 58849..60405 | - | 1557 | WP_000818556.1 | AAA family ATPase | - |
N0470_RS22900 () | 60668..61258 | - | 591 | WP_000194575.1 | hypothetical protein | - |
N0470_RS22905 () | 61258..61515 | - | 258 | WP_000343085.1 | hypothetical protein | - |
N0470_RS22910 () | 61869..64007 | + | 2139 | WP_000350638.1 | AAA family ATPase | - |
N0470_RS22915 () | 64169..64585 | - | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
N0470_RS22920 () | 64582..64812 | - | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
N0470_RS22925 () | 65108..65398 | + | 291 | WP_000111771.1 | hypothetical protein | - |
N0470_RS22930 () | 65388..66287 | + | 900 | WP_000963206.1 | nucleotide-binding protein | - |
N0470_RS22935 () | 66337..68562 | - | 2226 | WP_000698737.1 | P-loop NTPase fold protein | - |
N0470_RS22940 () | 68564..69652 | - | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
N0470_RS22945 () | 70195..70545 | + | 351 | WP_000493378.1 | hypothetical protein | - |
N0470_RS22950 () | 70596..71339 | + | 744 | WP_000129823.1 | hypothetical protein | - |
N0470_RS22955 () | 71336..72112 | + | 777 | WP_000015958.1 | site-specific integrase | - |
N0470_RS22960 () | 72170..72427 | - | 258 | WP_000764642.1 | hypothetical protein | - |
N0470_RS22965 () | 72556..72660 | - | 105 | WP_032409716.1 | hypothetical protein | - |
N0470_RS22970 () | 73190..74056 | + | 867 | WP_004118283.1 | replication initiation protein | - |
N0470_RS22975 () | 74233..74502 | - | 270 | WP_000339857.1 | hypothetical protein | - |
N0470_RS22980 () | 74917..76122 | + | 1206 | WP_000368714.1 | AAA family ATPase | - |
N0470_RS22985 () | 76122..77096 | + | 975 | WP_000064119.1 | ParB family protein | - |
N0470_RS22990 () | 77178..78449 | - | 1272 | WP_001754953.1 | Y-family DNA polymerase | - |
N0470_RS22995 () | 78449..78880 | - | 432 | WP_000776034.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
N0470_RS23000 () | 79286..80773 | + | 1488 | Protein_84 | group II intron reverse transcriptase/maturase | - |
N0470_RS23005 () | 80925..81622 | + | 698 | WP_223229472.1 | IS1 family transposase IS1X3 | Transposase |
N0470_RS23010 () | 81632..81940 | + | 309 | Protein_86 | replication initiation protein | - |
N0470_RS23015 () | 83343..84311 | + | 969 | WP_030005799.1 | IS5 family transposase IS903B | Transposase |
N0470_RS23020 () | 84451..84837 | - | 387 | WP_001039464.1 | plasmid stabilization protein StbA | - |
N0470_RS23025 () | 85419..85652 | + | 234 | Protein_89 | IS5 family transposase ISPan1 | Transposase |
N0470_RS23030 () | 85685..87199 | - | 1515 | Protein_90 | Tn3 family transposase TnpA_TnAs1 | Transposase |
N0470_RS23035 () | 87265..87969 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
N0470_RS23040 () | 88022..88777 | + | 756 | Protein_92 | IS110 family transposase IS5075 | Transposase |
N0470_RS23045 () | 89049..89135 | - | 87 | Protein_93 | Arm DNA-binding domain-containing protein | - |
N0470_RS23050 () | 89465..90280 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
N0470_RS23055 () | 90341..91144 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
N0470_RS23060 () | 91144..91980 | + | 837 | WP_000480972.1 | hypothetical protein | ARG |
N0470_RS23065 () | 92286..92528 | + | 243 | WP_000844627.1 | transposase | - |
N0470_RS23070 () | 92560..93210 | - | 651 | WP_001493764.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
N0470_RS23075 () | 93316..94515 | + | 1200 | WP_032153701.1 | Tetracycline resistance protein, class C | ARG |
N0470_RS23080 () | 94482..94670 | - | 189 | Protein_100 | IS91 family transposase | - |
N0470_RS23085 () | 94782..95087 | - | 306 | WP_001255015.1 | HTH-type transcriptional regulator HdfR | VF |
N0470_RS23090 () | 95115..96329 | - | 1215 | WP_023300759.1 | Bicyclomycin resistance protein | ARG |
N0470_RS23095 () | 96546..97430 | - | 885 | WP_021598067.1 | DUF3363 domain-containing protein | - |
N0470_RS23100 () | 97461..98954 | - | 1494 | WP_001120888.1 | IS91 family transposase ISVsa3 | Transposase |
N0470_RS23105 () | 99165..99389 | - | 225 | WP_000743213.1 | hypothetical protein | - |
N0470_RS23110 () | 99386..100123 | - | 738 | WP_001366550.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
N0470_RS23115 () | 100535..101239 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
N0470_RS23120 () | 101461..102216 | + | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
N0470_RS23125 () | 102342..103046 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
N0470_RS23130 () | 103096..103839 | + | 744 | Protein_110 | Beta-lactamase TEM | ARG |
N0470_RS23135 () | 104098..104574 | + | 477 | WP_013023839.1 | WbuC family cupin fold metalloprotein | - |
N0470_RS23140 () | 104621..105496 | - | 876 | WP_015387340.1 | Beta-lactamase CTX-M-1 | ARG |
N0470_RS23145 () | 105918..106622 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
N0470_RS23150 () | 108202..108436 | + | 235 | Protein_114 | type II toxin-antitoxin system RelE/ParE family toxin | - |
N0470_RS23155 () | 108564..108767 | + | 204 | Protein_115 | hypothetical protein | - |
N0470_RS23160 () | 108968..109318 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
N0470_RS23165 () | 109321..110283 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
N0470_RS23170 () | 110430..110723 | + | 294 | WP_032146011.1 | hypothetical protein | - |
N0470_RS23175 () | 110800..111483 | + | 684 | WP_000085883.1 | DNA methylase | - |
N0470_RS23180 () | 111484..111705 | + | 222 | WP_001104881.1 | hypothetical protein | - |
N0470_RS23185 () | 111719..112153 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
N0470_RS23190 () | 112204..112980 | + | 777 | WP_001383963.1 | hypothetical protein | - |
N0470_RS23195 () | 113398..113823 | + | 426 | WP_001198928.1 | antirestriction protein | - |
N0470_RS23200 () | 113870..114292 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
N0470_RS23205 () | 114289..114480 | + | 192 | WP_001027493.1 | hypothetical protein | - |
N0470_RS23210 () | 115518..115748 | + | 231 | WP_000218642.1 | hypothetical protein | - |
N0470_RS23215 () | 115800..117161 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
N0470_RS23220 () | 117208..117771 | + | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
N0470_RS23225 () | 117857..118318 | - | 462 | Protein_129 | hypothetical protein | - |
N0470_RS23230 () | 118620..119147 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
N0470_RS23235 () | 119205..119438 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
N0470_RS23240 () | 119499..121467 | + | 1969 | Protein_132 | ParB/RepB/Spo0J family partition protein | - |
N0470_RS23245 () | 121536..121970 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
N0470_RS23250 () | 121967..122729 | + | 763 | Protein_134 | plasmid SOS inhibition protein A | - |
- () | 122698..122922 | + | 225 | NuclAT_0 | - | - |
- () | 122698..122922 | + | 225 | NuclAT_0 | - | - |
- () | 122698..122922 | + | 225 | NuclAT_0 | - | - |
- () | 122698..122922 | + | 225 | NuclAT_0 | - | - |
N0470_RS23255 () | 122707..122886 | - | 180 | WP_001309233.1 | hypothetical protein | - |
- | 122855..122920 | - | 66 | - | - | Antitoxin Detail |
N0470_RS23260 () | 122908..123057 | + | 150 | Protein_136 | plasmid maintenance protein Mok | - |
N0470_RS23265 () | 122999..123124 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
N0470_RS23270 () | 123443..123739 | - | 297 | Protein_138 | hypothetical protein | - |
N0470_RS23275 () | 124039..124335 | + | 297 | WP_001272251.1 | hypothetical protein | - |
N0470_RS23280 () | 124446..125267 | + | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
N0470_RS23285 () | 125564..126211 | - | 648 | WP_015059008.1 | hypothetical protein | VF |
N0470_RS23290 () | 126488..126871 | + | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
N0470_RS23295 () | 127062..127748 | + | 687 | WP_015059009.1 | PAS domain-containing protein | - |
N0470_RS23300 () | 127842..128069 | + | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
N0470_RS23305 () | 128103..128468 | + | 366 | WP_021519752.1 | type IV conjugative transfer system pilin TraA | - |
N0470_RS23310 () | 128483..128794 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
N0470_RS23315 () | 128816..129382 | + | 567 | WP_000399794.1 | type IV conjugative transfer system protein TraE | - |
N0470_RS23320 () | 129369..130097 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
N0470_RS23325 () | 130097..131524 | + | 1428 | WP_032297072.1 | F-type conjugal transfer pilus assembly protein TraB | - |
N0470_RS23330 () | 131514..132104 | + | 591 | WP_000002778.1 | conjugal transfer pilus-stabilizing protein TraP | - |
N0470_RS23335 () | 132091..132288 | + | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
N0470_RS23340 () | 132300..132551 | + | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
N0470_RS23345 () | 132548..133063 | + | 516 | WP_000809902.1 | type IV conjugative transfer system lipoprotein TraV | - |
N0470_RS23350 () | 133198..133419 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
N0470_RS23355 () | 133579..136206 | + | 2628 | WP_015059012.1 | type IV secretion system protein TraC | - |
N0470_RS23360 () | 136203..136589 | + | 387 | WP_015059013.1 | type-F conjugative transfer system protein TrbI | - |
N0470_RS23365 () | 136586..137218 | + | 633 | WP_001203735.1 | type-F conjugative transfer system protein TraW | - |
N0470_RS23370 () | 137215..138207 | + | 993 | WP_259904979.1 | conjugal transfer pilus assembly protein TraU | - |
N0470_RS23375 () | 138234..138542 | + | 309 | WP_000412447.1 | hypothetical protein | - |
N0470_RS23380 () | 138605..139126 | + | 522 | WP_015059014.1 | hypothetical protein | - |
N0470_RS23385 () | 139153..139791 | + | 639 | WP_000087532.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
N0470_RS23390 () | 139788..140159 | + | 372 | WP_000056336.1 | hypothetical protein | - |
N0470_RS23395 () | 140185..140607 | + | 423 | WP_001229309.1 | HNH endonuclease signature motif containing protein | - |
N0470_RS23400 () | 140604..142454 | + | 1851 | WP_015059015.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
N0470_RS23405 () | 142481..142738 | + | 258 | WP_000864321.1 | conjugal transfer protein TrbE | - |
N0470_RS23410 () | 142731..143474 | + | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
N0470_RS23415 () | 143635..143871 | + | 237 | WP_000270010.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
N0470_RS23420 () | 143858..144403 | + | 546 | WP_000059817.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
N0470_RS23425 () | 144393..144707 | + | 315 | WP_001384255.1 | P-type conjugative transfer protein TrbJ | - |
N0470_RS23430 () | 144661..145053 | + | 393 | WP_000126338.1 | F-type conjugal transfer protein TrbF | - |
N0470_RS23435 () | 145040..146413 | + | 1374 | WP_000944325.1 | conjugal transfer pilus assembly protein TraH | - |
N0470_RS23440 () | 146410..149226 | + | 2817 | WP_015059018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
N0470_RS23445 () | 149259..149780 | + | 522 | WP_000632668.1 | conjugal transfer entry exclusion protein TraS | - |
N0470_RS23450 () | 149805..150536 | + | 732 | WP_021559024.1 | conjugal transfer complement resistance protein TraT | - |
N0470_RS23455 () | 150739..151476 | + | 738 | WP_015059020.1 | hypothetical protein | - |
N0470_RS23460 () | 151527..153770 | + | 2244 | WP_072646483.1 | type IV conjugative transfer system coupling protein TraD | - |
N0470_RS23465 () | 153770..159040 | + | 5271 | WP_061093447.1 | Multifunctional conjugation protein TraI | Relaxase |
N0470_RS23470 () | 159060..159806 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
N0470_RS23475 () | 159861..160421 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
N0470_RS23480 () | 160553..160753 | + | 201 | WP_015059022.1 | hypothetical protein | - |
N0470_RS23485 () | 161139..161738 | + | 600 | WP_032083981.1 | PIN domain-containing protein | - |
- () | 162333..162392 | - | 60 | NuclAT_1 | - | - |
- () | 162333..162392 | - | 60 | NuclAT_1 | - | - |
- () | 162333..162392 | - | 60 | NuclAT_1 | - | - |
- () | 162333..162392 | - | 60 | NuclAT_1 | - | - |
N0470_RS23490 () | 162437..162586 | + | 150 | WP_001312851.1 | Hok/Gef family protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
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