NZ_CP1036271..140136

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 140136 bp
Accession: NZ_CP103627        Location: 1..140136         Organism: Escherichia coli strain 4012       Replicon: plasmid pMB6206_1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5S78_RS23485 (1) 1..978 + 978 WP_000361611.1 RepB family plasmid replication initiator protein -
M5S78_RS23490 (1263) 1263..2003 - 741 WP_001066954.1 tyrosine-type recombinase/integrase -
M5S78_RS23495 (2124) 2124..2312 - 189 WP_001312821.1 hypothetical protein -
M5S78_RS23500 (2686) 2686..3588 - 903 WP_001312822.1 hypothetical protein VF
M5S78_RS23505 (3657) 3657..4766 - 1110 WP_000771475.1 SDR family oxidoreductase -
M5S78_RS23510 (5199) 5199..6152 - 954 WP_000280980.1 Protease 7 VF
M5S78_RS23515 (7449) 7449..7628 - 180 Protein_6 transposase -
M5S78_RS23520 (7767) 7767..8980 + 1214 WP_162842477.1 IS3 family transposase IS629 Transposase
M5S78_RS23525 (9128) 9128..9396 - 269 Protein_8 IS3 family transposase ISLad1 Transposase
M5S78_RS23530 (9453) 9453..10150 + 698 WP_095033700.1 IS1 family transposase IS1R Transposase
M5S78_RS23535 (10167) 10167..10364 - 198 Protein_10 colicin V -
M5S78_RS23540 (10342) 10342..10578 - 237 WP_014640552.1 colicin V immunity protein -
M5S78_RS23545 (11120) 11120..11323 - 204 Protein_12 hypothetical protein -
M5S78_RS23550 (11496) 11496..11663 + 168 Protein_13 colicin-B -
M5S78_RS23555 (11681) 11681..12208 - 528 WP_000203272.1 colicin B immunity protein -
M5S78_RS23560 (12452) 12452..13267 + 816 WP_001312845.1 lipid II-degrading bacteriocin colicin M -
M5S78_RS23565 (13317) 13317..13670 - 354 WP_000864812.1 colicin M immunity protein -
M5S78_RS23570 (13848) 13848..14639 - 792 WP_000016493.1 site-specific integrase -
M5S78_RS23575 (14636) 14636..15325 - 690 WP_000796228.1 hypothetical protein -
M5S78_RS23580 (15369) 15369..15719 - 351 WP_000493379.1 hypothetical protein -
M5S78_RS23585 (16264) 16264..17352 + 1089 WP_000952217.1 transcriptional repressor PifC -
M5S78_RS23590 (17354) 17354..19579 + 2226 WP_000698737.1 P-loop NTPase fold protein -
M5S78_RS23595 (19629) 19629..20528 - 900 WP_000963206.1 nucleotide-binding protein -
M5S78_RS23600 (20518) 20518..20808 - 291 WP_000111771.1 hypothetical protein -
M5S78_RS23605 (21104) 21104..21334 + 231 WP_001261287.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
M5S78_RS23610 (21331) 21331..21747 + 417 WP_001044768.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
M5S78_RS23615 (21909) 21909..24047 - 2139 WP_000350638.1 AAA family ATPase -
M5S78_RS23620 (24401) 24401..24658 + 258 WP_000343085.1 hypothetical protein -
M5S78_RS23625 (24658) 24658..25248 + 591 WP_000194575.1 hypothetical protein -
M5S78_RS23630 (25511) 25511..26971 + 1461 WP_202745975.1 AAA family ATPase -
M5S78_RS23635 (27259) 27259..27876 + 618 WP_000521603.1 ProQ/FINO family protein -
M5S78_RS23640 (28274) 28274..29536 + 1263 WP_000608644.1 IS1380 family transposase ISEcp1 Transposase
M5S78_RS23645 (29792) 29792..30667 + 876 WP_015387340.1 Beta-lactamase CTX-M-1 ARG
M5S78_RS23650 (30714) 30714..31007 - 294 WP_116961751.1 WbuC family cupin fold metalloprotein -
M5S78_RS23655 (31224) 31224..32303 - 1080 WP_001089727.1 permease -
M5S78_RS23660 (32408) 32408..32731 + 324 WP_001175594.1 metalloregulator ArsR/SmtB family transcription factor -
M5S78_RS23665 (32892) 32892..33212 + 321 Protein_36 NAD(P)H-dependent oxidoreductase -
M5S78_RS23670 (33265) 33265..33969 - 705 WP_001067834.1 IS6 family transposase IS26 Transposase
M5S78_RS23675 (34035) 34035..35549 + 1515 Protein_38 Tn3 family transposase TnpA_TnAs1 Transposase
M5S78_RS23680 (35607) 35607..35849 + 243 WP_000844627.1 transposase -
M5S78_RS23685 (35881) 35881..36531 - 651 WP_000164043.1 tetracycline resistance transcriptional repressor TetR(A) -
M5S78_RS23690 (36637) 36637..37836 + 1200 WP_077248803.1 Tetracycline resistance protein, class C ARG
M5S78_RS23695 (37868) 37868..38752 - 885 WP_000058717.1 EamA family transporter -
M5S78_RS23700 (38890) 38890..39282 - 393 WP_001351729.1 isochorismatase family cysteine hydrolase -
M5S78_RS23705 (39286) 39286..40866 + 1581 Protein_44 Tn3 family transposase TnpA_TnAs1 Transposase
M5S78_RS23710 (40917) 40917..41621 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
M5S78_RS23715 (41687) 41687..41971 + 285 Protein_46 IS6 family transposase IS26 Transposase
M5S78_RS23720 (42161) 42161..42976 - 816 WP_000018329.1 Aminoglycoside 3'-phosphotransferase ARG
M5S78_RS23725 (43127) 43127..43831 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
M5S78_RS23730 (44279) 44279..45292 - 1014 WP_000845048.1 IS91 family transposase ISAzo26 Transposase
M5S78_RS23735 (45448) 45448..45921 + 474 WP_004201280.1 Dihydrofolate reductase type 1 ARG
M5S78_RS23740 (45991) 45991..46695 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
M5S78_RS23745 (46750) 46750..47007 + 258 Protein_52 hypothetical protein -
M5S78_RS23750 (47153) 47153..48016 + 864 WP_000612791.1 SDR family oxidoreductase -
M5S78_RS23755 (48054) 48054..48299 + 246 WP_001354008.1 GrpB family protein -
M5S78_RS23760 (48768) 48768..49559 + 792 WP_000034420.1 Dihydropteroate synthase ARG
M5S78_RS23765 (49562) 49562..49837 - 276 WP_109023896.1 hypothetical protein -
M5S78_RS23770 (49860) 49860..50492 + 633 WP_020802982.1 IS256 family transposase IS406 Transposase
M5S78_RS23775 (50739) 50739..51071 - 333 WP_000800531.1 quaternary ammonium compound efflux SMR transporter QacL -
M5S78_RS23780 (51194) 51194..52032 - 839 Protein_59 Streptomycin 3''-adenylyltransferase ARG
M5S78_RS23785 (52121) 52121..53011 - 891 WP_223151485.1 alpha/beta fold putative hydrolase EstX -
M5S78_RS23790 (53428) 53428..54921 - 1494 WP_015344975.1 IS91 family transposase ISVsa3 Transposase
M5S78_RS23795 (55033) 55033..55338 - 306 WP_001255015.1 HTH-type transcriptional regulator CynR VF
M5S78_RS23800 (55366) 55366..56580 - 1215 WP_000214122.1 Bicyclomycin resistance protein ARG
M5S78_RS23805 (56797) 56797..57681 - 885 WP_001447541.1 DUF3363 domain-containing protein -
M5S78_RS23810 (57712) 57712..58218 - 507 Protein_65 IS91 family transposase ISVsa3 Transposase
M5S78_RS23815 (58283) 58283..58987 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
M5S78_RS23820 (59034) 59034..61334 + 2301 Protein_67 Tn3 family transposase TnpA_Tn3 Transposase
M5S78_RS23825 (61411) 61411..62115 + 705 WP_001067834.1 IS6 family transposase IS26 Transposase
M5S78_RS23830 (62169) 62169..63217 - 1049 Protein_69 IS3 family transposase ISKpn11 Transposase
M5S78_RS23835 (63309) 63309..63851 - 543 WP_002063889.1 AAA family ATPase -
M5S78_RS23840 (63864) 63864..64724 - 861 WP_000557452.1 SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD ARG
M5S78_RS23845 (64831) 64831..65535 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
M5S78_RS23850 (65601) 65601..66146 + 546 Protein_73 Tn3 family transposase TnpA_Tn3 Transposase
M5S78_RS23855 (66182) 66182..66597 - 416 Protein_74 IS1 family transposase -
M5S78_RS23860 (66846) 66846..67247 - 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
M5S78_RS23865 (67180) 67180..67437 - 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
M5S78_RS23870 (67530) 67530..68183 - 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
M5S78_RS23875 (69120) 69120..69545 + 426 WP_000422741.1 IS66 family transposase ISEc23 Transposase
M5S78_RS23880 (69542) 69542..69892 + 351 WP_000624722.1 IS66 family transposase ISEc23 Transposase
M5S78_RS23885 (69923) 69923..71536 + 1614 WP_001366169.1 IS66 family transposase ISEc23 Transposase
M5S78_RS23890 (71662) 71662..72519 - 858 WP_000774297.1 incFII family plasmid replication initiator RepA -
M5S78_RS23895 (72512) 72512..72994 - 483 WP_001273588.1 hypothetical protein -
M5S78_RS23900 (72987) 72987..73034 - 48 WP_229471593.1 hypothetical protein -
M5S78_RS23905 (73025) 73025..73276 + 252 WP_223195197.1 replication protein RepA -
M5S78_RS23910 (73293) 73293..73550 - 258 WP_000083845.1 replication regulatory protein RepA -
M5S78_RS23915 (73834) 73834..73983 - 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
- (74027) 74027..74088 + 62 NuclAT_1 - Antitoxin Detail
- (74027) 74027..74088 + 62 NuclAT_1 - Antitoxin Detail
- (74027) 74027..74088 + 62 NuclAT_1 - Antitoxin Detail
- (74027) 74027..74088 + 62 NuclAT_1 - Antitoxin Detail
M5S78_RS23920 (74344) 74344..74418 - 75 Protein_87 endonuclease -
M5S78_RS23925 (74664) 74664..74876 - 213 WP_001299730.1 ANR family transcriptional regulator -
M5S78_RS23930 (75012) 75012..75572 - 561 WP_000139315.1 fertility inhibition protein FinO -
M5S78_RS23935 (75675) 75675..76535 - 861 WP_000704513.1 putative protein YcjY VF
M5S78_RS23940 (76594) 76594..77340 - 747 WP_000205749.1 conjugal transfer pilus acetylase TraX -
M5S78_RS23945 (77360) 77360..82630 - 5271 WP_000986962.1 Multifunctional conjugation protein TraI Relaxase
M5S78_RS23950 (82712) 82712..82939 + 228 WP_000450520.1 toxin-antitoxin system antitoxin VapB Antitoxin Detail
M5S78_RS23955 (82939) 82939..83337 + 399 WP_000911313.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
M5S78_RS23960 (83346) 83346..85499 - 2154 WP_000009324.1 type IV conjugative transfer system coupling protein TraD -
M5S78_RS23965 (85752) 85752..86483 - 732 WP_023565183.1 conjugal transfer complement resistance protein TraT -
M5S78_RS23970 (86515) 86515..87012 - 498 WP_000605857.1 entry exclusion protein -
M5S78_RS23975 (87028) 87028..89850 - 2823 WP_001007018.1 conjugal transfer mating-pair stabilization protein TraG -
M5S78_RS23980 (89847) 89847..91220 - 1374 WP_001517790.1 conjugal transfer pilus assembly protein TraH -
M5S78_RS23985 (91220) 91220..91600 - 381 WP_001389370.1 F-type conjugal transfer protein TrbF -
M5S78_RS23990 (91587) 91587..91928 - 342 WP_001443031.1 P-type conjugative transfer protein TrbJ -
M5S78_RS23995 (91858) 91858..92403 - 546 WP_000059851.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
M5S78_RS24000 (92390) 92390..92674 - 285 WP_000624109.1 type-F conjugative transfer system pilin chaperone TraQ -
M5S78_RS24005 (92755) 92755..93069 + 315 WP_001324103.1 hypothetical protein -
M5S78_RS24010 (93071) 93071..93418 - 348 WP_001287910.1 conjugal transfer protein TrbA -
M5S78_RS24015 (93434) 93434..94177 - 744 WP_001030393.1 type-F conjugative transfer system pilin assembly protein TraF -
M5S78_RS24020 (94170) 94170..94427 - 258 WP_000864318.1 conjugal transfer protein TrbE -
M5S78_RS24025 (94454) 94454..96262 - 1809 WP_000821841.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
M5S78_RS24030 (96259) 96259..96897 - 639 WP_000777700.1 type-F conjugative transfer system pilin assembly protein TrbC -
M5S78_RS24035 (96906) 96906..97898 - 993 WP_000830183.1 conjugal transfer pilus assembly protein TraU -
M5S78_RS24040 (97895) 97895..98527 - 633 WP_001203720.1 type-F conjugative transfer system protein TraW -
M5S78_RS24045 (98524) 98524..98910 - 387 WP_000099686.1 type-F conjugative transfer system protein TrbI -
M5S78_RS24050 (98907) 98907..100529 - 1623 Protein_113 type IV secretion system protein TraC -
M5S78_RS24055 (100562) 100562..102175 - 1614 WP_001366169.1 IS66 family transposase ISEc23 Transposase
M5S78_RS24060 (102206) 102206..102556 - 351 WP_000624722.1 IS66 family transposase ISEc23 Transposase
M5S78_RS24065 (102553) 102553..102978 - 426 WP_000422741.1 IS66 family transposase ISEc23 Transposase
M5S78_RS24070 (103064) 103064..104074 - 1011 Protein_117 TraC family protein -
M5S78_RS24075 (104234) 104234..104455 - 222 WP_001278689.1 conjugal transfer protein TraR -
M5S78_RS24080 (104590) 104590..105105 - 516 WP_000809838.1 type IV conjugative transfer system lipoprotein TraV -
M5S78_RS24085 (105102) 105102..105353 - 252 WP_001038342.1 conjugal transfer protein TrbG -
M5S78_RS24090 (105365) 105365..105562 - 198 WP_001324648.1 conjugal transfer protein TrbD -
M5S78_RS24095 (105549) 105549..106139 - 591 WP_001376242.1 conjugal transfer pilus-stabilizing protein TraP -
M5S78_RS24100 (106129) 106129..107556 - 1428 WP_000146685.1 F-type conjugal transfer pilus assembly protein TraB -
M5S78_RS24105 (107556) 107556..108284 - 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
M5S78_RS24110 (108271) 108271..108837 - 567 WP_000399792.1 type IV conjugative transfer system protein TraE -
M5S78_RS24115 (108859) 108859..109170 - 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
M5S78_RS24120 (109185) 109185..109550 - 366 WP_000994779.1 type IV conjugative transfer system pilin TraA -
M5S78_RS24125 (109583) 109583..109984 - 402 WP_001369361.1 conjugal transfer relaxosome DNA-bindin protein TraY -
M5S78_RS24130 (110077) 110077..110766 - 690 WP_000283385.1 conjugal transfer transcriptional regulator TraJ -
M5S78_RS24135 (110953) 110953..111336 - 384 WP_001151524.1 conjugal transfer relaxosome DNA-binding protein TraM -
M5S78_RS24140 (111657) 111657..112259 + 603 WP_072156291.1 hypothetical protein VF
M5S78_RS24145 (112556) 112556..113377 - 822 WP_001234469.1 DUF932 domain-containing protein -
M5S78_RS24150 (113496) 113496..113783 - 288 WP_000107535.1 hypothetical protein -
M5S78_RS24155 (113808) 113808..114014 - 207 WP_000547971.1 hypothetical protein -
M5S78_RS24160 (114084) 114084..114257 + 174 Protein_135 hypothetical protein -
M5S78_RS24165 (114255) 114255..114485 - 231 WP_001426396.1 hypothetical protein -
M5S78_RS24170 (114705) 114705..114830 - 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
M5S78_RS24175 (114772) 114772..114921 - 150 Protein_138 plasmid maintenance protein Mok -
- (114907) 114907..115131 - 225 NuclAT_0 - Antitoxin Detail
- (114907) 114907..115131 - 225 NuclAT_0 - Antitoxin Detail
- (114907) 114907..115131 - 225 NuclAT_0 - Antitoxin Detail
- (114907) 114907..115131 - 225 NuclAT_0 - Antitoxin Detail
M5S78_RS24180 (114943) 114943..115131 + 189 WP_001299721.1 hypothetical protein -
M5S78_RS24185 (115100) 115100..115862 - 763 Protein_140 plasmid SOS inhibition protein A -
M5S78_RS24190 (115859) 115859..116293 - 435 WP_064770609.1 conjugation system SOS inhibitor PsiB -
M5S78_RS24195 (116348) 116348..116545 - 198 Protein_142 hypothetical protein -
M5S78_RS24200 (116573) 116573..116806 - 234 WP_000005987.1 DUF905 family protein -
M5S78_RS24205 (116874) 116874..117413 - 540 WP_000290840.1 single-stranded DNA-binding protein -
M5S78_RS24210 (117439) 117439..117645 - 207 WP_000275856.1 hypothetical protein -
M5S78_RS24215 (117715) 117715..117795 + 81 Protein_146 hypothetical protein -
M5S78_RS24220 (117978) 117978..118147 - 170 Protein_147 hypothetical protein -
M5S78_RS24225 (118784) 118784..119755 - 972 WP_000817028.1 ParB/RepB/Spo0J family plasmid partition protein -
M5S78_RS24230 (119755) 119755..120921 - 1167 WP_001238646.1 Sporulation initiation inhibitor protein Soj VF
M5S78_RS24240 (122403) 122403..124604 - 2202 WP_000973520.1 Ferric aerobactin receptor VF
M5S78_RS24245 (124630) 124630..125963 - 1334 Protein_152 L-lysine N6-monooxygenase VF
M5S78_RS24250 (125960) 125960..127702 - 1743 WP_001015721.1 Aerobactin synthase VF
M5S78_RS24255 (127702) 127702..128649 - 948 WP_000011910.1 N(6)-hydroxylysine O-acetyltransferase VF
M5S78_RS24260 (128650) 128650..130374 - 1725 WP_000602863.1 N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase VF
M5S78_RS24265 (130510) 130510..131703 + 1194 WP_000095526.1 MFS transporter -
M5S78_RS24270 (132083) 132083..132463 - 381 WP_001318207.1 fluoride efflux transporter CrcB -
M5S78_RS24275 (132804) 132804..133217 - 414 Protein_158 phosphopyruvate hydratase -
M5S78_RS24280 (133215) 133215..133472 + 258 Protein_159 transposase -
M5S78_RS24285 (133706) 133706..134563 - 858 WP_000968139.1 Manganese transport system membrane protein MntB ARG
M5S78_RS24290 (134560) 134560..135417 - 858 WP_001101723.1 Manganese transport system membrane protein MntB ARG
M5S78_RS24295 (135414) 135414..136241 - 828 WP_000983710.1 Iron(3+)-hydroxamate import ATP-binding protein FhuC VF
M5S78_RS24300 (136241) 136241..137155 - 915 WP_000949004.1 Putative metal ABC transporter substrate-binding protein Hpf VF
M5S78_RS24305 (137511) 137511..138208 + 698 WP_223155668.1 IS1 family transposase IS1S Transposase
M5S78_RS24310 (138388) 138388..138901 - 514 Protein_165 DUF4113 domain-containing protein -
M5S78_RS24315 (138962) 138962..139066 - 105 Protein_166 AAA family ATPase -
M5S78_RS24320 (139068) 139068..139391 - 324 Protein_167 IS21 family transposase IS21 Transposase

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance