MGE detailed information
MGE type: Conjugative plasmid MGE length: 140136 bp
Accession: NZ_CP103627 Location: 1..140136 Organism: Escherichia coli strain 4012 Replicon: plasmid pMB6206_1
Accession: NZ_CP103627 Location: 1..140136 Organism: Escherichia coli strain 4012 Replicon: plasmid pMB6206_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
M5S78_RS23485 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
M5S78_RS23490 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
M5S78_RS23495 (2124) | 2124..2312 | - | 189 | WP_001312821.1 | hypothetical protein | - |
M5S78_RS23500 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
M5S78_RS23505 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
M5S78_RS23510 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
M5S78_RS23515 (7449) | 7449..7628 | - | 180 | Protein_6 | transposase | - |
M5S78_RS23520 (7767) | 7767..8980 | + | 1214 | WP_162842477.1 | IS3 family transposase IS629 | Transposase |
M5S78_RS23525 (9128) | 9128..9396 | - | 269 | Protein_8 | IS3 family transposase ISLad1 | Transposase |
M5S78_RS23530 (9453) | 9453..10150 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
M5S78_RS23535 (10167) | 10167..10364 | - | 198 | Protein_10 | colicin V | - |
M5S78_RS23540 (10342) | 10342..10578 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
M5S78_RS23545 (11120) | 11120..11323 | - | 204 | Protein_12 | hypothetical protein | - |
M5S78_RS23550 (11496) | 11496..11663 | + | 168 | Protein_13 | colicin-B | - |
M5S78_RS23555 (11681) | 11681..12208 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
M5S78_RS23560 (12452) | 12452..13267 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
M5S78_RS23565 (13317) | 13317..13670 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
M5S78_RS23570 (13848) | 13848..14639 | - | 792 | WP_000016493.1 | site-specific integrase | - |
M5S78_RS23575 (14636) | 14636..15325 | - | 690 | WP_000796228.1 | hypothetical protein | - |
M5S78_RS23580 (15369) | 15369..15719 | - | 351 | WP_000493379.1 | hypothetical protein | - |
M5S78_RS23585 (16264) | 16264..17352 | + | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
M5S78_RS23590 (17354) | 17354..19579 | + | 2226 | WP_000698737.1 | P-loop NTPase fold protein | - |
M5S78_RS23595 (19629) | 19629..20528 | - | 900 | WP_000963206.1 | nucleotide-binding protein | - |
M5S78_RS23600 (20518) | 20518..20808 | - | 291 | WP_000111771.1 | hypothetical protein | - |
M5S78_RS23605 (21104) | 21104..21334 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
M5S78_RS23610 (21331) | 21331..21747 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
M5S78_RS23615 (21909) | 21909..24047 | - | 2139 | WP_000350638.1 | AAA family ATPase | - |
M5S78_RS23620 (24401) | 24401..24658 | + | 258 | WP_000343085.1 | hypothetical protein | - |
M5S78_RS23625 (24658) | 24658..25248 | + | 591 | WP_000194575.1 | hypothetical protein | - |
M5S78_RS23630 (25511) | 25511..26971 | + | 1461 | WP_202745975.1 | AAA family ATPase | - |
M5S78_RS23635 (27259) | 27259..27876 | + | 618 | WP_000521603.1 | ProQ/FINO family protein | - |
M5S78_RS23640 (28274) | 28274..29536 | + | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
M5S78_RS23645 (29792) | 29792..30667 | + | 876 | WP_015387340.1 | Beta-lactamase CTX-M-1 | ARG |
M5S78_RS23650 (30714) | 30714..31007 | - | 294 | WP_116961751.1 | WbuC family cupin fold metalloprotein | - |
M5S78_RS23655 (31224) | 31224..32303 | - | 1080 | WP_001089727.1 | permease | - |
M5S78_RS23660 (32408) | 32408..32731 | + | 324 | WP_001175594.1 | metalloregulator ArsR/SmtB family transcription factor | - |
M5S78_RS23665 (32892) | 32892..33212 | + | 321 | Protein_36 | NAD(P)H-dependent oxidoreductase | - |
M5S78_RS23670 (33265) | 33265..33969 | - | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
M5S78_RS23675 (34035) | 34035..35549 | + | 1515 | Protein_38 | Tn3 family transposase TnpA_TnAs1 | Transposase |
M5S78_RS23680 (35607) | 35607..35849 | + | 243 | WP_000844627.1 | transposase | - |
M5S78_RS23685 (35881) | 35881..36531 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
M5S78_RS23690 (36637) | 36637..37836 | + | 1200 | WP_077248803.1 | Tetracycline resistance protein, class C | ARG |
M5S78_RS23695 (37868) | 37868..38752 | - | 885 | WP_000058717.1 | EamA family transporter | - |
M5S78_RS23700 (38890) | 38890..39282 | - | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
M5S78_RS23705 (39286) | 39286..40866 | + | 1581 | Protein_44 | Tn3 family transposase TnpA_TnAs1 | Transposase |
M5S78_RS23710 (40917) | 40917..41621 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
M5S78_RS23715 (41687) | 41687..41971 | + | 285 | Protein_46 | IS6 family transposase IS26 | Transposase |
M5S78_RS23720 (42161) | 42161..42976 | - | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
M5S78_RS23725 (43127) | 43127..43831 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
M5S78_RS23730 (44279) | 44279..45292 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
M5S78_RS23735 (45448) | 45448..45921 | + | 474 | WP_004201280.1 | Dihydrofolate reductase type 1 | ARG |
M5S78_RS23740 (45991) | 45991..46695 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
M5S78_RS23745 (46750) | 46750..47007 | + | 258 | Protein_52 | hypothetical protein | - |
M5S78_RS23750 (47153) | 47153..48016 | + | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
M5S78_RS23755 (48054) | 48054..48299 | + | 246 | WP_001354008.1 | GrpB family protein | - |
M5S78_RS23760 (48768) | 48768..49559 | + | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
M5S78_RS23765 (49562) | 49562..49837 | - | 276 | WP_109023896.1 | hypothetical protein | - |
M5S78_RS23770 (49860) | 49860..50492 | + | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
M5S78_RS23775 (50739) | 50739..51071 | - | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
M5S78_RS23780 (51194) | 51194..52032 | - | 839 | Protein_59 | Streptomycin 3''-adenylyltransferase | ARG |
M5S78_RS23785 (52121) | 52121..53011 | - | 891 | WP_223151485.1 | alpha/beta fold putative hydrolase EstX | - |
M5S78_RS23790 (53428) | 53428..54921 | - | 1494 | WP_015344975.1 | IS91 family transposase ISVsa3 | Transposase |
M5S78_RS23795 (55033) | 55033..55338 | - | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
M5S78_RS23800 (55366) | 55366..56580 | - | 1215 | WP_000214122.1 | Bicyclomycin resistance protein | ARG |
M5S78_RS23805 (56797) | 56797..57681 | - | 885 | WP_001447541.1 | DUF3363 domain-containing protein | - |
M5S78_RS23810 (57712) | 57712..58218 | - | 507 | Protein_65 | IS91 family transposase ISVsa3 | Transposase |
M5S78_RS23815 (58283) | 58283..58987 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
M5S78_RS23820 (59034) | 59034..61334 | + | 2301 | Protein_67 | Tn3 family transposase TnpA_Tn3 | Transposase |
M5S78_RS23825 (61411) | 61411..62115 | + | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
M5S78_RS23830 (62169) | 62169..63217 | - | 1049 | Protein_69 | IS3 family transposase ISKpn11 | Transposase |
M5S78_RS23835 (63309) | 63309..63851 | - | 543 | WP_002063889.1 | AAA family ATPase | - |
M5S78_RS23840 (63864) | 63864..64724 | - | 861 | WP_000557452.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
M5S78_RS23845 (64831) | 64831..65535 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
M5S78_RS23850 (65601) | 65601..66146 | + | 546 | Protein_73 | Tn3 family transposase TnpA_Tn3 | Transposase |
M5S78_RS23855 (66182) | 66182..66597 | - | 416 | Protein_74 | IS1 family transposase | - |
M5S78_RS23860 (66846) | 66846..67247 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
M5S78_RS23865 (67180) | 67180..67437 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
M5S78_RS23870 (67530) | 67530..68183 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
M5S78_RS23875 (69120) | 69120..69545 | + | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
M5S78_RS23880 (69542) | 69542..69892 | + | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
M5S78_RS23885 (69923) | 69923..71536 | + | 1614 | WP_001366169.1 | IS66 family transposase ISEc23 | Transposase |
M5S78_RS23890 (71662) | 71662..72519 | - | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
M5S78_RS23895 (72512) | 72512..72994 | - | 483 | WP_001273588.1 | hypothetical protein | - |
M5S78_RS23900 (72987) | 72987..73034 | - | 48 | WP_229471593.1 | hypothetical protein | - |
M5S78_RS23905 (73025) | 73025..73276 | + | 252 | WP_223195197.1 | replication protein RepA | - |
M5S78_RS23910 (73293) | 73293..73550 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
M5S78_RS23915 (73834) | 73834..73983 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
- (74027) | 74027..74088 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
- (74027) | 74027..74088 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
- (74027) | 74027..74088 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
- (74027) | 74027..74088 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
M5S78_RS23920 (74344) | 74344..74418 | - | 75 | Protein_87 | endonuclease | - |
M5S78_RS23925 (74664) | 74664..74876 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
M5S78_RS23930 (75012) | 75012..75572 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
M5S78_RS23935 (75675) | 75675..76535 | - | 861 | WP_000704513.1 | putative protein YcjY | VF |
M5S78_RS23940 (76594) | 76594..77340 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
M5S78_RS23945 (77360) | 77360..82630 | - | 5271 | WP_000986962.1 | Multifunctional conjugation protein TraI | Relaxase |
M5S78_RS23950 (82712) | 82712..82939 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
M5S78_RS23955 (82939) | 82939..83337 | + | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
M5S78_RS23960 (83346) | 83346..85499 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
M5S78_RS23965 (85752) | 85752..86483 | - | 732 | WP_023565183.1 | conjugal transfer complement resistance protein TraT | - |
M5S78_RS23970 (86515) | 86515..87012 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
M5S78_RS23975 (87028) | 87028..89850 | - | 2823 | WP_001007018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
M5S78_RS23980 (89847) | 89847..91220 | - | 1374 | WP_001517790.1 | conjugal transfer pilus assembly protein TraH | - |
M5S78_RS23985 (91220) | 91220..91600 | - | 381 | WP_001389370.1 | F-type conjugal transfer protein TrbF | - |
M5S78_RS23990 (91587) | 91587..91928 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
M5S78_RS23995 (91858) | 91858..92403 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
M5S78_RS24000 (92390) | 92390..92674 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
M5S78_RS24005 (92755) | 92755..93069 | + | 315 | WP_001324103.1 | hypothetical protein | - |
M5S78_RS24010 (93071) | 93071..93418 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
M5S78_RS24015 (93434) | 93434..94177 | - | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
M5S78_RS24020 (94170) | 94170..94427 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
M5S78_RS24025 (94454) | 94454..96262 | - | 1809 | WP_000821841.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
M5S78_RS24030 (96259) | 96259..96897 | - | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
M5S78_RS24035 (96906) | 96906..97898 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
M5S78_RS24040 (97895) | 97895..98527 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
M5S78_RS24045 (98524) | 98524..98910 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
M5S78_RS24050 (98907) | 98907..100529 | - | 1623 | Protein_113 | type IV secretion system protein TraC | - |
M5S78_RS24055 (100562) | 100562..102175 | - | 1614 | WP_001366169.1 | IS66 family transposase ISEc23 | Transposase |
M5S78_RS24060 (102206) | 102206..102556 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
M5S78_RS24065 (102553) | 102553..102978 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
M5S78_RS24070 (103064) | 103064..104074 | - | 1011 | Protein_117 | TraC family protein | - |
M5S78_RS24075 (104234) | 104234..104455 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
M5S78_RS24080 (104590) | 104590..105105 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
M5S78_RS24085 (105102) | 105102..105353 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
M5S78_RS24090 (105365) | 105365..105562 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
M5S78_RS24095 (105549) | 105549..106139 | - | 591 | WP_001376242.1 | conjugal transfer pilus-stabilizing protein TraP | - |
M5S78_RS24100 (106129) | 106129..107556 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
M5S78_RS24105 (107556) | 107556..108284 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
M5S78_RS24110 (108271) | 108271..108837 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
M5S78_RS24115 (108859) | 108859..109170 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
M5S78_RS24120 (109185) | 109185..109550 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
M5S78_RS24125 (109583) | 109583..109984 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
M5S78_RS24130 (110077) | 110077..110766 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
M5S78_RS24135 (110953) | 110953..111336 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
M5S78_RS24140 (111657) | 111657..112259 | + | 603 | WP_072156291.1 | hypothetical protein | VF |
M5S78_RS24145 (112556) | 112556..113377 | - | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
M5S78_RS24150 (113496) | 113496..113783 | - | 288 | WP_000107535.1 | hypothetical protein | - |
M5S78_RS24155 (113808) | 113808..114014 | - | 207 | WP_000547971.1 | hypothetical protein | - |
M5S78_RS24160 (114084) | 114084..114257 | + | 174 | Protein_135 | hypothetical protein | - |
M5S78_RS24165 (114255) | 114255..114485 | - | 231 | WP_001426396.1 | hypothetical protein | - |
M5S78_RS24170 (114705) | 114705..114830 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
M5S78_RS24175 (114772) | 114772..114921 | - | 150 | Protein_138 | plasmid maintenance protein Mok | - |
- (114907) | 114907..115131 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
- (114907) | 114907..115131 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
- (114907) | 114907..115131 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
- (114907) | 114907..115131 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
M5S78_RS24180 (114943) | 114943..115131 | + | 189 | WP_001299721.1 | hypothetical protein | - |
M5S78_RS24185 (115100) | 115100..115862 | - | 763 | Protein_140 | plasmid SOS inhibition protein A | - |
M5S78_RS24190 (115859) | 115859..116293 | - | 435 | WP_064770609.1 | conjugation system SOS inhibitor PsiB | - |
M5S78_RS24195 (116348) | 116348..116545 | - | 198 | Protein_142 | hypothetical protein | - |
M5S78_RS24200 (116573) | 116573..116806 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
M5S78_RS24205 (116874) | 116874..117413 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
M5S78_RS24210 (117439) | 117439..117645 | - | 207 | WP_000275856.1 | hypothetical protein | - |
M5S78_RS24215 (117715) | 117715..117795 | + | 81 | Protein_146 | hypothetical protein | - |
M5S78_RS24220 (117978) | 117978..118147 | - | 170 | Protein_147 | hypothetical protein | - |
M5S78_RS24225 (118784) | 118784..119755 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
M5S78_RS24230 (119755) | 119755..120921 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
M5S78_RS24240 (122403) | 122403..124604 | - | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
M5S78_RS24245 (124630) | 124630..125963 | - | 1334 | Protein_152 | L-lysine N6-monooxygenase | VF |
M5S78_RS24250 (125960) | 125960..127702 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
M5S78_RS24255 (127702) | 127702..128649 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
M5S78_RS24260 (128650) | 128650..130374 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
M5S78_RS24265 (130510) | 130510..131703 | + | 1194 | WP_000095526.1 | MFS transporter | - |
M5S78_RS24270 (132083) | 132083..132463 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
M5S78_RS24275 (132804) | 132804..133217 | - | 414 | Protein_158 | phosphopyruvate hydratase | - |
M5S78_RS24280 (133215) | 133215..133472 | + | 258 | Protein_159 | transposase | - |
M5S78_RS24285 (133706) | 133706..134563 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
M5S78_RS24290 (134560) | 134560..135417 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
M5S78_RS24295 (135414) | 135414..136241 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
M5S78_RS24300 (136241) | 136241..137155 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
M5S78_RS24305 (137511) | 137511..138208 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
M5S78_RS24310 (138388) | 138388..138901 | - | 514 | Protein_165 | DUF4113 domain-containing protein | - |
M5S78_RS24315 (138962) | 138962..139066 | - | 105 | Protein_166 | AAA family ATPase | - |
M5S78_RS24320 (139068) | 139068..139391 | - | 324 | Protein_167 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
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