MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 82867 bp
Accession: NZ_CP103523 Location: 1..82867 Organism: Escherichia coli strain 2779 - blood draw same patient as MB9267 Replicon: plasmid pMB9272_2
Accession: NZ_CP103523 Location: 1..82867 Organism: Escherichia coli strain 2779 - blood draw same patient as MB9267 Replicon: plasmid pMB9272_2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M5S63_RS25240 (1) | 1..756 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| M5S63_RS25245 (1344) | 1344..2510 | + | 1167 | WP_000772446.1 | hypothetical protein | VF |
| M5S63_RS25250 (2510) | 2510..3481 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| M5S63_RS25255 (4348) | 4348..5250 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| M5S63_RS25260 (5247) | 5247..5558 | + | 312 | WP_011254640.1 | hypothetical protein | - |
| M5S63_RS25265 (5635) | 5635..6318 | + | 684 | WP_000086185.1 | DNA methylase | - |
| M5S63_RS25270 (6319) | 6319..6540 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| M5S63_RS25275 (6470) | 6470..6988 | + | 519 | WP_123325260.1 | DUF1380 family protein | - |
| M5S63_RS25280 (7039) | 7039..7815 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| M5S63_RS25285 (8232) | 8232..8657 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| M5S63_RS25290 (8704) | 8704..9126 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| M5S63_RS25295 (9123) | 9123..9314 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| M5S63_RS25300 (9628) | 9628..11295 | - | 1668 | WP_052991863.1 | group II intron reverse transcriptase/maturase | - |
| M5S63_RS25305 (12024) | 12024..12178 | - | 155 | Protein_13 | hypothetical protein | - |
| M5S63_RS25310 (12692) | 12692..12922 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| M5S63_RS25315 (12974) | 12974..14335 | + | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| M5S63_RS25320 (14383) | 14383..14946 | + | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| M5S63_RS25325 (15031) | 15031..15186 | - | 156 | Protein_17 | hypothetical protein | - |
| M5S63_RS25330 (15299) | 15299..15967 | - | 669 | WP_259409802.1 | HNH endonuclease signature motif containing protein | - |
| M5S63_RS25335 (16074) | 16074..16778 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| M5S63_RS25340 (16839) | 16839..19295 | + | 2457 | Protein_20 | Multifunctional conjugation protein TraI | Relaxase |
| M5S63_RS25345 (19315) | 19315..20061 | + | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| M5S63_RS25350 (20116) | 20116..20676 | + | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| M5S63_RS25355 (20807) | 20807..21019 | + | 213 | WP_013023861.1 | hypothetical protein | - |
| M5S63_RS25360 (21532) | 21532..21818 | + | 287 | Protein_24 | DUF2726 domain-containing protein | - |
| - (21785) | 21785..21845 | - | 61 | NuclAT_0 | - | Antitoxin Detail |
| - (21785) | 21785..21845 | - | 61 | NuclAT_0 | - | Antitoxin Detail |
| - (21785) | 21785..21845 | - | 61 | NuclAT_0 | - | Antitoxin Detail |
| - (21785) | 21785..21845 | - | 61 | NuclAT_0 | - | Antitoxin Detail |
| M5S63_RS25365 (21890) | 21890..22024 | + | 135 | WP_023144756.1 | Hok/Gef family protein | Toxin Detail |
| M5S63_RS25370 (22321) | 22321..22575 | + | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| M5S63_RS25375 (22735) | 22735..23481 | - | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| M5S63_RS25380 (23496) | 23496..25037 | - | 1542 | WP_002431311.1 | IS21 family transposase ISEc12 | Transposase |
| M5S63_RS25385 (25268) | 25268..25399 | + | 132 | Protein_29 | protein CopA/IncA | - |
| M5S63_RS25390 (25399) | 25399..25473 | + | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| M5S63_RS25395 (25466) | 25466..26323 | + | 858 | WP_000130640.1 | incFII family plasmid replication initiator RepA | - |
| M5S63_RS25400 (27025) | 27025..27165 | + | 141 | WP_001333237.1 | hypothetical protein | - |
| M5S63_RS25405 (27540) | 27540..28244 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5S63_RS25410 (28310) | 28310..28822 | + | 513 | Protein_34 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| M5S63_RS25415 (28846) | 28846..29451 | - | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| M5S63_RS25420 (29546) | 29546..32443 | + | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| M5S63_RS25425 (32580) | 32580..32981 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| M5S63_RS25430 (32914) | 32914..33171 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| M5S63_RS25435 (33264) | 33264..33773 | - | 510 | WP_259409803.1 | CPBP family intramembrane metalloprotease | - |
| M5S63_RS25440 (33764) | 33764..34468 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5S63_RS25445 (34612) | 34612..35166 | + | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| M5S63_RS25450 (35297) | 35297..36127 | + | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| M5S63_RS25455 (36265) | 36265..36705 | + | 441 | Protein_43 | CatB-related O-acetyltransferase | - |
| M5S63_RS25460 (36759) | 36759..37463 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5S63_RS25465 (37540) | 37540..39759 | - | 2220 | Protein_45 | Tn3 family transposase TnpA_Tn3 | Transposase |
| M5S63_RS25470 (39824) | 39824..40117 | + | 294 | WP_116961751.1 | WbuC family cupin fold metalloprotein | - |
| M5S63_RS25475 (40164) | 40164..41039 | - | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| M5S63_RS25480 (41295) | 41295..41366 | - | 72 | Protein_48 | hypothetical protein | - |
| M5S63_RS25485 (41421) | 41421..42125 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5S63_RS25490 (42189) | 42189..42527 | + | 339 | Protein_50 | Tn3 family transposase TnpR_Tn3 | Transposase |
| M5S63_RS25495 (42710) | 42710..43570 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| M5S63_RS25500 (43717) | 43717..43998 | + | 282 | Protein_52 | transposase zinc-binding domain-containing protein | - |
| M5S63_RS25505 (44174) | 44174..44878 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| M5S63_RS25510 (44932) | 44932..45297 | - | 366 | Protein_54 | chromate transporter | - |
| M5S63_RS25515 (45453) | 45453..45656 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| M5S63_RS25520 (45784) | 45784..46623 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| M5S63_RS25525 (46617) | 46617..46964 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| M5S63_RS25530 (47170) | 47170..47958 | - | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| M5S63_RS25535 (48089) | 48089..48562 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| M5S63_RS25540 (48720) | 48720..49367 | + | 648 | Protein_60 | IS91 family transposase ISAzo26 | Transposase |
| M5S63_RS25545 (49413) | 49413..50117 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| M5S63_RS25550 (50182) | 50182..50370 | + | 189 | Protein_62 | IS1 family transposase | - |
| M5S63_RS25555 (50377) | 50377..50898 | + | 522 | Protein_63 | IS4 family transposase IS10R | Transposase |
| M5S63_RS25560 (50908) | 50908..51324 | - | 417 | WP_000275180.1 | Transposon Tn10 TetD protein | VF |
| M5S63_RS25565 (51412) | 51412..52005 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| M5S63_RS25570 (52118) | 52118..53323 | - | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| M5S63_RS25575 (53405) | 53405..54028 | + | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| M5S63_RS25580 (54006) | 54006..54113 | - | 108 | Protein_68 | transcriptional regulator | - |
| M5S63_RS25590 (54870) | 54870..55058 | + | 189 | Protein_70 | hypothetical protein | - |
| M5S63_RS25595 (55093) | 55093..55221 | - | 129 | Protein_71 | IS481 family transposase | - |
| M5S63_RS25600 (55254) | 55254..56423 | - | 1170 | WP_001072355.1 | hypothetical protein | - |
| M5S63_RS25605 (56955) | 56955..57223 | + | 269 | Protein_73 | type II toxin-antitoxin system ParD family antitoxin | - |
| M5S63_RS25610 (57210) | 57210..57499 | + | 290 | Protein_74 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| M5S63_RS25615 (57566) | 57566..57748 | + | 183 | WP_042065278.1 | hypothetical protein | - |
| M5S63_RS25620 (57869) | 57869..58609 | + | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| M5S63_RS25625 (58894) | 58894..59871 | - | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| M5S63_RS25630 (60667) | 60667..61080 | - | 414 | Protein_78 | integrase core domain-containing protein | - |
| M5S63_RS25635 (61085) | 61085..61363 | - | 279 | Protein_79 | pdcB | - |
| M5S63_RS25640 (61391) | 61391..61570 | - | 180 | WP_001513661.1 | hypothetical protein | - |
| M5S63_RS25645 (61575) | 61575..61955 | - | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| M5S63_RS25650 (61955) | 61955..62176 | - | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| M5S63_RS25655 (62359) | 62359..63915 | + | 1557 | WP_001553856.1 | type I restriction-modification system subunit M | - |
| M5S63_RS25660 (63912) | 63912..65183 | + | 1272 | WP_023142242.1 | restriction endonuclease subunit S | - |
| M5S63_RS25665 (65305) | 65305..68421 | + | 3117 | WP_031311986.1 | HsdR family type I site-specific deoxyribonuclease | - |
| M5S63_RS25670 (68635) | 68635..69332 | + | 698 | WP_223364856.1 | IS1 family transposase IS1G | Transposase |
| M5S63_RS25675 (69469) | 69469..70401 | - | 933 | WP_000991832.1 | S-4TM family putative pore-forming effector | - |
| M5S63_RS25680 (70405) | 70405..71400 | - | 996 | WP_000246636.1 | hypothetical protein | - |
| M5S63_RS25685 (71865) | 71865..74003 | + | 2139 | WP_000350635.1 | AAA family ATPase | - |
| M5S63_RS25690 (74165) | 74165..74581 | - | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| M5S63_RS25695 (74578) | 74578..74808 | - | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| M5S63_RS25700 (75115) | 75115..78234 | + | 3120 | WP_023909028.1 | hypothetical protein | - |
| M5S63_RS25705 (78497) | 78497..79630 | + | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| M5S63_RS25710 (79650) | 79650..79934 | + | 285 | WP_000642771.1 | hypothetical protein | - |
| M5S63_RS25715 (79931) | 79931..80128 | - | 198 | WP_000215657.1 | hypothetical protein | - |
| M5S63_RS25720 (80762) | 80762..80980 | + | 219 | WP_023909027.1 | type II toxin-antitoxin system antitoxin CcdA | - |
| M5S63_RS25725 (80982) | 80982..81287 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | - |
| M5S63_RS25730 (81288) | 81288..82094 | + | 807 | WP_000016982.1 | site-specific integrase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|