MGE detailed information

MGE type: Non-Mobilizable plasmid        MGE length: 188688 bp
Accession: NZ_CP102988        Location: 1..188688         Organism: Klebsiella pneumoniae strain KPA2       Replicon: plasmid p1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW253_RS25865 (NW253_25865) 1..1011 + 1011 WP_017900946.1 RepB family plasmid replication initiator protein -
NW253_RS25870 (NW253_25870) 1833..2560 - 728 Protein_1 site-specific integrase -
NW253_RS25875 (NW253_25875) 2663..2803 - 141 Protein_2 hypothetical protein -
NW253_RS25880 (NW253_25880) 2910..3183 + 274 Protein_3 IS3 family transposase -
NW253_RS25885 (NW253_25885) 3321..3857 - 537 WP_048322225.1 hypothetical protein -
NW253_RS25890 (NW253_25890) 4068..5041 - 974 Protein_5 IS3 family transposase -
NW253_RS25895 (NW253_25895) 5108..6124 + 1017 WP_032430783.1 IS110 family transposase ISSaen1 Transposase
NW253_RS25900 (NW253_25900) 7703..8800 - 1098 WP_049015454.1 RepB family plasmid replication initiator protein -
NW253_RS25905 (NW253_25905) 9940..10908 - 969 WP_258809045.1 IS5 family transposase IS903B Transposase
NW253_RS25910 (NW253_25910) 11032..11720 + 689 WP_227538326.1 IS1 family transposase IS1X4 Transposase
NW253_RS25915 (NW253_25915) 11736..12134 - 399 Protein_10 IS5 family transposase IS903B Transposase
NW253_RS25920 (NW253_25920) 12230..13198 - 969 WP_016151349.1 IS5 family transposase IS903B Transposase
NW253_RS25925 (NW253_25925) 13493..14518 - 1026 WP_001101446.1 IS110 family transposase ISAve1 Transposase
NW253_RS25930 (NW253_25930) 15003..15911 + 909 WP_025999290.1 HNH endonuclease -
NW253_RS25935 (NW253_25935) 16299..16649 - 351 WP_017900727.1 DUF305 domain-containing protein -
NW253_RS25940 (NW253_25940) 16793..17224 - 432 WP_000790483.1 silver-binding protein SilE -
NW253_RS25945 (NW253_25945) 17475..18950 - 1476 WP_004118652.1 copper/silver sensor histidine kinase SilS -
NW253_RS25950 (NW253_25950) 18943..19623 - 681 WP_000697968.1 Transcriptional regulatory protein CusR VF
NW253_RS25955 (NW253_25955) 19813..21198 + 1386 WP_000475503.1 Cation efflux system protein CusC VF
NW253_RS25960 (NW253_25960) 21227..21580 + 354 WP_001246153.1 cation efflux system protein CusF -
NW253_RS25965 (NW253_25965) 21694..22986 + 1293 WP_001485328.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
NW253_RS25970 (NW253_25970) 22997..26143 + 3147 WP_000574021.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
NW253_RS25975 (NW253_25975) 26230..26670 + 441 WP_017900725.1 DUF411 domain-containing protein -
NW253_RS25980 (NW253_25980) 26768..29239 + 2472 WP_128306664.1 Ag(+)-translocating P-type ATPase SilP -
NW253_RS25985 (NW253_25985) 29280..29477 + 198 WP_000843497.1 DUF2933 domain-containing protein -
NW253_RS25990 (NW253_25990) 29511..30248 - 738 WP_004118669.1 Murein DD-endopeptidase MepM VF
NW253_RS25995 (NW253_25995) 30537..30986 - 450 WP_025999288.1 copper resistance protein -
NW253_RS26000 (NW253_26000) 31221..33038 + 1818 WP_017900722.1 multicopper oxidase PcoA -
NW253_RS26005 (NW253_26005) 33044..33934 + 891 WP_001378118.1 copper resistance outer membrane transporter PcoB -
NW253_RS26010 (NW253_26010) 33974..34354 + 381 WP_000025662.1 copper resistance system metallochaperone PcoC -
NW253_RS26015 (NW253_26015) 34359..35288 + 930 WP_017900721.1 copper resistance inner membrane protein PcoD -
NW253_RS26020 (NW253_26020) 35343..36023 + 681 WP_001188930.1 Transcriptional activator protein CopR VF
NW253_RS26025 (NW253_26025) 36020..37420 + 1401 WP_004152084.1 copper resistance membrane spanning protein PcoS -
NW253_RS26030 (NW253_26030) 37636..38070 + 435 WP_017900720.1 copper resistance system metallochaperone PcoE -
NW253_RS26035 (NW253_26035) 38270..38638 - 369 Protein_34 transposase -
NW253_RS26040 (NW253_26040) 38661..39409 - 749 Protein_35 IS66 family transposase ISKpn24 Transposase
NW253_RS26045 (NW253_26045) 39458..39670 - 213 Protein_36 IS66 family insertion sequence element accessory protein TnpB -
NW253_RS26050 (NW253_26050) 39704..40672 + 969 WP_000654811.1 IS5 family transposase IS903B Transposase
NW253_RS26055 (NW253_26055) 40769..40909 - 141 Protein_38 galactoside O-acetyltransferase -
NW253_RS26060 (NW253_26060) 40975..42228 - 1254 WP_032430739.1 lactose permease -
NW253_RS26065 (NW253_26065) 42280..45354 - 3075 WP_032430741.1 beta-galactosidase -
NW253_RS26070 (NW253_26070) 45476..46558 - 1083 WP_024241646.1 DNA-binding transcriptional repressor LacI -
NW253_RS26075 (NW253_26075) 46594..46676 - 83 Protein_42 hypothetical protein -
NW253_RS26080 (NW253_26080) 46810..46956 + 147 Protein_43 tyrosine-type recombinase/integrase -
NW253_RS26085 (NW253_26085) 46981..47364 + 384 WP_257965221.1 hypothetical protein -
NW253_RS26090 (NW253_26090) 47457..47975 - 519 WP_012541817.1 hypothetical protein -
NW253_RS26095 (NW253_26095) 47988..48842 - 855 WP_012541818.1 WYL domain-containing protein -
NW253_RS26100 (NW253_26100) 48979..50160 + 1182 WP_023287181.1 hypothetical protein -
NW253_RS26105 (NW253_26105) 50157..52385 + 2229 WP_032430744.1 ThiF family adenylyltransferase -
NW253_RS26110 (NW253_26110) 52438..53579 + 1142 Protein_49 translesion error-prone DNA polymerase V subunit UmuC -
NW253_RS26115 (NW253_26115) 53680..54123 + 444 WP_023287184.1 DUF2384 domain-containing protein Antitoxin Detail
NW253_RS26120 (NW253_26120) 54120..54590 + 471 WP_004144067.1 RES family NAD+ phosphorylase Toxin Detail
NW253_RS26125 (NW253_26125) 54677..54997 + 321 Protein_52 IS5 family transposase ISPan1 Transposase
NW253_RS26130 (NW253_26130) 55030..55998 + 969 WP_074423483.1 IS5 family transposase IS903B Transposase
NW253_RS26135 (NW253_26135) 56337..57092 - 756 Protein_54 M24 family metallopeptidase -
NW253_RS26145 (NW253_26145) 58529..58900 - 372 WP_258809046.1 aminopeptidase P family N-terminal domain-containing protein -
NW253_RS26150 (NW253_26150) 58987..59880 - 894 Protein_57 LysR substrate-binding domain-containing protein -
NW253_RS26155 (NW253_26155) 59938..60635 + 698 WP_095033700.1 IS1 family transposase IS1R Transposase
NW253_RS26160 (NW253_26160) 60651..61340 + 690 Protein_59 putative oxidoreductase YghA VF
NW253_RS26165 (NW253_26165) 61436..62080 - 645 WP_017900990.1 Pentapeptide repeat protein ARG
NW253_RS26170 (NW253_26170) 62163..63152 - 990 WP_017900991.1 Psp operon transcriptional activator VF
NW253_RS26175 (NW253_26175) 63308..63976 + 669 WP_003020532.1 phage shock protein PspA -
NW253_RS26180 (NW253_26180) 64031..64255 + 225 WP_004193245.1 envelope stress response membrane protein PspB -
NW253_RS26185 (NW253_26185) 64255..64614 + 360 WP_004193243.1 envelope stress response membrane protein PspC -
NW253_RS26190 (NW253_26190) 64623..64853 + 231 WP_004193241.1 phage shock protein PspD -
NW253_RS26195 (NW253_26195) 65042..65230 - 189 Protein_66 LacI family transcriptional regulator -
NW253_RS26200 (NW253_26200) 65188..66009 - 822 WP_004193237.1 hypothetical protein -
NW253_RS26205 (NW253_26205) 66204..67343 - 1140 WP_004236386.1 Beta-lactamase ARG
NW253_RS26210 (NW253_26210) 67454..68329 + 876 WP_004193231.1 LysR family transcriptional regulator AmpR -
NW253_RS26215 (NW253_26215) 68333..68698 - 366 WP_025999322.1 hydrogenase maturation nickel metallochaperone HypA -
NW253_RS26220 (NW253_26220) 68591..68917 + 327 WP_075886493.1 SMR family transporter -
NW253_RS26225 (NW253_26225) 68964..69668 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NW253_RS26230 (NW253_26230) 69720..70121 + 402 Protein_73 IS6 family transposase IS26 Transposase
NW253_RS26235 (NW253_26235) 70311..71126 - 816 WP_000018329.1 Aminoglycoside 3'-phosphotransferase ARG
NW253_RS26240 (NW253_26240) 71277..71981 + 705 WP_001067834.1 IS6 family transposase IS26 Transposase
NW253_RS26245 (NW253_26245) 72103..73008 + 906 WP_000219391.1 hypothetical protein ARG
NW253_RS26250 (NW253_26250) 73005..74243 + 1239 WP_000004159.1 macrolide resistance MFS transporter Mrx(A) -
NW253_RS26255 (NW253_26255) 74243..74827 + 585 WP_001137892.1 macrolide-binding transcriptional repressor MphR(A) -
NW253_RS26260 (NW253_26260) 75222..75926 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NW253_RS26265 (NW253_26265) 75903..77348 + 1446 WP_224715715.1 Methyl-accepting chemotaxis protein McpQ VF
NW253_RS26270 (NW253_26270) 77496..77813 - 318 WP_258809047.1 IS5 family transposase ISPan1 Transposase
NW253_RS26275 (NW253_26275) 77833..78315 + 483 WP_180806969.1 hypothetical protein -
NW253_RS26280 (NW253_26280) 79207..79419 + 213 WP_004181742.1 hypothetical protein -
NW253_RS26285 (NW253_26285) 79513..79791 + 279 WP_040217023.1 DUF1778 domain-containing protein -
NW253_RS26290 (NW253_26290) 80473..80877 + 405 WP_004118061.1 DUF2251 domain-containing protein -
NW253_RS26295 (NW253_26295) 81286..82448 + 1163 WP_088941748.1 IS3 family transposase ISSty2 Transposase
NW253_RS26300 (NW253_26300) 83274..84236 - 963 Protein_87 kinase -
NW253_RS26305 (NW253_26305) 84269..85236 + 968 Protein_88 IS5 family transposase IS903B Transposase
NW253_RS26310 (NW253_26310) 85832..86011 - 180 WP_007372130.1 hypothetical protein -
NW253_RS26315 (NW253_26315) 86090..86767 + 678 Protein_90 IS1 family transposase IS1A Transposase
NW253_RS26320 (NW253_26320) 87227..87427 + 201 Protein_91 IS3 family transposase ISYps8 Transposase
NW253_RS26325 (NW253_26325) 87484..87809 - 326 Protein_92 IS5 family transposase IS903B Transposase
NW253_RS26330 (NW253_26330) 87897..88919 + 1023 WP_017901324.1 IS21 family transposase ISSen3 Transposase
NW253_RS26335 (NW253_26335) 88916..89698 + 783 WP_032437422.1 IS21 family transposase ISSen3 Transposase
NW253_RS26340 (NW253_26340) 89765..89992 + 228 Protein_95 hypothetical protein -
NW253_RS26345 (NW253_26345) 90429..92636 + 2208 WP_048322244.1 AAA family ATPase -
NW253_RS26350 (NW253_26350) 92639..95215 + 2577 WP_017901322.1 nuclease domain-containing protein -
NW253_RS26355 (NW253_26355) 95468..95698 + 231 WP_001261275.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
NW253_RS26360 (NW253_26360) 95695..96111 + 417 WP_000754567.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
NW253_RS26365 (NW253_26365) 96419..97387 + 969 WP_016151349.1 IS5 family transposase IS903B Transposase
NW253_RS26370 (NW253_26370) 97558..97977 - 420 WP_011251286.1 helix-turn-helix domain-containing protein Antitoxin Detail
NW253_RS26375 (NW253_26375) 97974..98285 - 312 WP_011251285.1 type II toxin-antitoxin system HigB family toxin Toxin Detail
NW253_RS26380 (NW253_26380) 98490..98927 - 438 Protein_103 IS3 family transposase ISEc27 Transposase
NW253_RS26385 (NW253_26385) 99041..99379 + 339 WP_023288266.1 IS66 family transposase ISSgsp1 Transposase
NW253_RS26390 (NW253_26390) 99376..99723 + 348 WP_032430752.1 IS66 family transposase ISCfr14 Transposase
NW253_RS26395 (NW253_26395) 99772..101305 + 1534 Protein_106 IS66 family transposase ISEc22 Transposase
NW253_RS26400 (NW253_26400) 101345..101524 + 180 Protein_107 IS5 family transposase IS903B Transposase
NW253_RS26405 (NW253_26405) 102069..103049 - 981 WP_048293850.1 IS5 family transposase ISKpn26 Transposase
NW253_RS26410 (NW253_26410) 103248..104615 - 1368 WP_023329010.1 formimidoylglutamate deiminase -
NW253_RS26415 (NW253_26415) 104718..105479 + 762 WP_017900871.1 histidine utilization repressor -
NW253_RS26420 (NW253_26420) 105476..106033 + 558 WP_017900872.1 HutD family protein -
NW253_RS26425 (NW253_26425) 106067..107599 - 1533 WP_032430756.1 aromatic amino acid ammonia-lyase -
NW253_RS26430 (NW253_26430) 107610..108485 - 876 WP_017900874.1 ABC transporter substrate-binding protein -
NW253_RS26435 (NW253_26435) 108516..109196 - 681 WP_014228066.1 ABC transporter permease -
NW253_RS26440 (NW253_26440) 109199..109843 - 645 WP_032430757.1 ABC transporter permease subunit -
NW253_RS26445 (NW253_26445) 109840..110937 - 1098 WP_032430758.1 Osmoprotectant import ATP-binding protein OsmV VF
NW253_RS26450 (NW253_26450) 111445..113121 + 1677 WP_017900877.1 urocanate hydratase -
NW253_RS26455 (NW253_26455) 113175..114569 + 1395 WP_032430759.1 cytosine permease -
NW253_RS26460 (NW253_26460) 114581..115789 + 1209 WP_032430760.1 imidazolonepropionase -
NW253_RS26465 (NW253_26465) 115782..116591 + 810 WP_032430761.1 N-formylglutamate deformylase -
NW253_RS26470 (NW253_26470) 117176..117274 + 99 Protein_121 hypothetical protein -
NW253_RS26475 (NW253_26475) 117332..117739 + 408 WP_032440835.1 IS66 family transposase ISCro1 Transposase
NW253_RS26480 (NW253_26480) 117736..117960 + 225 Protein_123 IS66 family transposase IS682 Transposase
NW253_RS26485 (NW253_26485) 118028..118453 - 426 Protein_124 IS5 family transposase ISPan1 Transposase
NW253_RS26495 (NW253_26495) 120187..120975 - 789 WP_040217257.1 hypothetical protein -
NW253_RS26500 (NW253_26500) 120996..121616 - 621 WP_223343781.1 conjugative transfer protein MobI(A/C) -
NW253_RS26505 (NW253_26505) 122035..122670 + 636 WP_223343780.1 hypothetical protein -
NW253_RS26510 (NW253_26510) 122983..123393 + 411 WP_048322240.1 hypothetical protein -
NW253_RS26515 (NW253_26515) 123705..123980 + 276 WP_072072826.1 IS1-like element transposase -
NW253_RS26520 (NW253_26520) 124025..124375 + 351 Protein_131 IS1 family transposase IS1X2 Transposase
NW253_RS26525 (NW253_26525) 124399..125202 - 804 WP_049125651.1 hypothetical protein -
NW253_RS26530 (NW253_26530) 125263..126609 - 1347 Protein_133 ISNCY family transposase ISLad2 Transposase
NW253_RS26535 (NW253_26535) 126848..127207 + 360 Protein_134 LysR substrate-binding domain-containing protein -
NW253_RS26540 (NW253_26540) 127369..128805 - 1437 WP_048298736.1 PLP-dependent aminotransferase family protein -
NW253_RS26545 (NW253_26545) 128904..129692 + 789 WP_023288270.1 arylamine N-acetyltransferase -
NW253_RS26550 (NW253_26550) 130034..130619 + 586 Protein_137 IS110 family transposase IS1618 Transposase
NW253_RS26555 (NW253_26555) 131019..131222 + 204 Protein_138 Tn3 family transposase TnpA_Tn3 Transposase
NW253_RS26560 (NW253_26560) 131224..132192 + 969 WP_185954916.1 IS5 family transposase IS903B Transposase
NW253_RS26565 (NW253_26565) 132496..134029 + 1534 Protein_140 IS3 family transposase ISKpn38 Transposase
NW253_RS26570 (NW253_26570) 134206..134838 + 633 WP_001567369.1 hypothetical protein -
NW253_RS26575 (NW253_26575) 134867..136270 - 1404 WP_001567368.1 ISNCY family transposase ISKpn21 Transposase
NW253_RS26580 (NW253_26580) 136477..136947 - 471 Protein_143 IS3 family transposase -
NW253_RS26585 (NW253_26585) 136949..137422 + 474 Protein_144 hypothetical protein -
NW253_RS26590 (NW253_26590) 137551..137766 + 216 WP_048322237.1 hypothetical protein -
NW253_RS26595 (NW253_26595) 137828..140941 - 3114 WP_065800289.1 HsdR family type I site-specific deoxyribonuclease -
NW253_RS26600 (NW253_26600) 140934..142253 - 1320 WP_032430798.1 AAA family ATPase -
NW253_RS26605 (NW253_26605) 142267..143436 - 1170 WP_064160287.1 restriction endonuclease subunit S -
NW253_RS26610 (NW253_26610) 143433..144989 - 1557 WP_032430763.1 type I restriction-modification system subunit M -
NW253_RS26615 (NW253_26615) 145193..147058 - 1866 WP_032430764.1 DUF262 domain-containing protein -
NW253_RS26620 (NW253_26620) 148146..148340 - 195 Protein_151 integrase core domain-containing protein -
NW253_RS26625 (NW253_26625) 149415..149657 + 243 WP_223343779.1 hypothetical protein -
NW253_RS26630 (NW253_26630) 149675..150643 + 969 WP_074187388.1 IS5 family transposase IS903B Transposase
NW253_RS26635 (NW253_26635) 151076..151573 + 498 WP_125337164.1 carboxypeptidase-like regulatory domain-containing protein -
NW253_RS26640 (NW253_26640) 151761..152908 + 1148 WP_101987929.1 IS3 family transposase ISEhe3 Transposase
NW253_RS26645 (NW253_26645) 153034..154002 - 969 WP_185954915.1 IS5 family transposase IS903B Transposase
NW253_RS26650 (NW253_26650) 154024..154239 - 216 WP_162779047.1 hypothetical protein -
NW253_RS26655 (NW253_26655) 154326..154580 - 255 WP_048322234.1 Hha/YmoA family nucleoid-associated regulatory protein -
NW253_RS26660 (NW253_26660) 154758..155894 + 1137 WP_048322233.1 tyrosine-type recombinase/integrase -
NW253_RS26665 (NW253_26665) 155960..156277 - 318 WP_004213829.1 hypothetical protein -
NW253_RS26670 (NW253_26670) 156429..156752 - 324 WP_004197568.1 hypothetical protein -
NW253_RS26675 (NW253_26675) 156894..157880 - 987 WP_258809044.1 IS5 family transposase IS903B Transposase
NW253_RS26680 (NW253_26680) 157976..158944 - 969 WP_004099053.1 IS5 family transposase IS903B Transposase
NW253_RS26685 (NW253_26685) 159034..159993 - 960 WP_032435645.1 DNA replication terminus site-binding protein -
NW253_RS26690 (NW253_26690) 160036..160443 - 408 WP_016946349.1 hypothetical protein -
NW253_RS26695 (NW253_26695) 160453..160896 - 444 WP_020477096.1 hypothetical protein -
NW253_RS26700 (NW253_26700) 160917..161992 - 1076 Protein_167 IS3 family transposase ISEc27 Transposase
NW253_RS26705 (NW253_26705) 162160..163128 + 969 WP_048322231.1 IS110 family transposase ISSm3 Transposase
NW253_RS26710 (NW253_26710) 163147..163311 - 165 Protein_169 IS3 family transposase IS2 Transposase
NW253_RS26715 (NW253_26715) 163374..164071 + 698 WP_223343773.1 IS1 family transposase IS1R Transposase
NW253_RS26720 (NW253_26720) 164492..165229 + 738 WP_025999344.1 glycine zipper domain-containing protein -
NW253_RS26725 (NW253_26725) 165309..165791 + 483 WP_023288353.1 hypothetical protein -
NW253_RS26730 (NW253_26730) 165873..166985 + 1113 WP_072096726.1 tellurite resistance domain protein -
NW253_RS26735 (NW253_26735) 167035..168483 + 1449 WP_219620421.1 SrfA family protein -
NW253_RS26740 (NW253_26740) 168501..171569 + 3069 WP_023288355.1 virulence factor SrfB -
NW253_RS26745 (NW253_26745) 171569..174283 + 2715 WP_101987918.1 virulence factor SrfC family protein -
NW253_RS26750 (NW253_26750) 174277..175296 + 1020 WP_053067570.1 hypothetical protein -
NW253_RS26755 (NW253_26755) 175293..177260 + 1968 WP_048322228.1 hypothetical protein VF
NW253_RS26760 (NW253_26760) 177260..177985 + 726 WP_017901260.1 putative ABC transporter ATP-binding protein YknY VF
NW253_RS26765 (NW253_26765) 177975..179189 + 1215 WP_025999345.1 hypothetical protein VF
NW253_RS26770 (NW253_26770) 179240..180808 + 1569 WP_017901262.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -
NW253_RS26775 (NW253_26775) 180844..181347 + 504 WP_017901263.1 hypothetical protein -
NW253_RS26780 (NW253_26780) 181407..181862 - 456 WP_032747566.1 IrmA family protein -
NW253_RS26785 (NW253_26785) 181956..183548 - 1593 WP_101987917.1 IS66 family transposase ISKox1 Transposase
NW253_RS26790 (NW253_26790) 183579..183929 - 351 WP_048322226.1 IS66 family transposase ISKox1 Transposase
NW253_RS26795 (NW253_26795) 183926..184366 - 441 WP_004189163.1 IS66 family transposase ISKox1 Transposase
NW253_RS26800 (NW253_26800) 184451..184745 + 295 Protein_187 DUF4113 domain-containing protein -
NW253_RS26805 (NW253_26805) 184824..185052 + 229 Protein_188 type II toxin-antitoxin system Phd/YefM family antitoxin -
NW253_RS26810 (NW253_26810) 185822..186793 - 972 WP_004117790.1 ParB/RepB/Spo0J family plasmid partition protein -
NW253_RS26815 (NW253_26815) 186793..187959 - 1167 WP_017900945.1 hypothetical protein VF

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance