MGE detailed information
MGE type: Conjugative plasmid MGE length: 149702 bp
Accession: NZ_CP102855 Location: 1..149702 Organism: Escherichia coli strain 573 Replicon: plasmid p573-2
Accession: NZ_CP102855 Location: 1..149702 Organism: Escherichia coli strain 573 Replicon: plasmid p573-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NWH85_RS24090 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| NWH85_RS24095 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| NWH85_RS24100 (2124) | 2124..2312 | - | 189 | WP_014640565.1 | hypothetical protein | - |
| NWH85_RS24105 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| NWH85_RS24110 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| NWH85_RS24115 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| NWH85_RS24120 (7449) | 7449..7628 | - | 180 | Protein_6 | transposase | - |
| NWH85_RS24125 (7767) | 7767..8506 | + | 740 | Protein_7 | IS3 family transposase IS629 | Transposase |
| NWH85_RS24130 (9179) | 9179..10687 | + | 1509 | WP_001189111.1 | group II intron reverse transcriptase/maturase | - |
| NWH85_RS24135 (10771) | 10771..11250 | + | 480 | Protein_9 | IS3 family transposase IS629 | Transposase |
| NWH85_RS24140 (11398) | 11398..11666 | - | 269 | Protein_10 | IS3 family transposase ISLad1 | Transposase |
| NWH85_RS24145 (11723) | 11723..12420 | + | 698 | WP_103215986.1 | IS1-like element IS1A family transposase | - |
| NWH85_RS24150 (12498) | 12498..13887 | - | 1390 | Protein_12 | ISNCY family transposase ISKpn21 | Transposase |
| NWH85_RS24155 (14197) | 14197..14346 | - | 150 | Protein_13 | IS3 family transposase IS2 | Transposase |
| NWH85_RS24160 (14524) | 14524..15717 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| NWH85_RS24165 (16940) | 16940..18176 | - | 1237 | Protein_15 | IS3 family transposase IS2 | Transposase |
| NWH85_RS24170 (18803) | 18803..19096 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| NWH85_RS24175 (19154) | 19154..19353 | - | 200 | Protein_17 | lysis protein | - |
| NWH85_RS24180 (19907) | 19907..20934 | + | 1028 | Protein_18 | integrase core domain-containing protein | - |
| NWH85_RS24185 (22245) | 22245..23360 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| NWH85_RS24190 (23500) | 23500..27159 | + | 3660 | WP_001111199.1 | Multidrug efflux ATP-binding/permease protein | VF |
| NWH85_RS24195 (27263) | 27263..28492 | + | 1230 | WP_000933675.1 | Enterochelin esterase | VF |
| NWH85_RS24200 (28577) | 28577..29533 | + | 957 | WP_064055648.1 | hypothetical protein | VF |
| NWH85_RS24205 (29578) | 29578..31755 | - | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| NWH85_RS24210 (31990) | 31990..32687 | + | 698 | WP_103215986.1 | IS1-like element IS1A family transposase | - |
| NWH85_RS24215 (32704) | 32704..32901 | - | 198 | Protein_25 | colicin V | - |
| NWH85_RS24220 (32879) | 32879..33115 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| NWH85_RS24225 (33604) | 33604..34301 | + | 698 | WP_103215986.1 | IS1-like element IS1A family transposase | - |
| NWH85_RS24230 (34434) | 34434..34637 | - | 204 | Protein_28 | hypothetical protein | - |
| NWH85_RS24235 (34810) | 34810..34977 | + | 168 | Protein_29 | colicin-B | - |
| NWH85_RS24240 (34995) | 34995..35522 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| NWH85_RS24245 (35766) | 35766..36581 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| NWH85_RS24250 (36631) | 36631..36984 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| NWH85_RS24255 (37162) | 37162..37953 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| NWH85_RS24260 (37950) | 37950..38639 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| NWH85_RS24265 (38683) | 38683..39033 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| NWH85_RS24270 (39565) | 39565..43386 | - | 3822 | WP_064055658.1 | hypothetical protein | - |
| NWH85_RS24275 (43606) | 43606..43791 | + | 186 | Protein_37 | hypothetical protein | - |
| NWH85_RS24280 (43809) | 43809..44156 | - | 348 | WP_000142450.1 | DUF6404 family protein | - |
| NWH85_RS24285 (44458) | 44458..44940 | - | 483 | WP_032302322.1 | hypothetical protein | - |
| NWH85_RS24290 (45057) | 45057..45905 | - | 849 | WP_023154360.1 | 3'-5' exonuclease | - |
| NWH85_RS24295 (45951) | 45951..46229 | - | 279 | WP_097309154.1 | type II toxin-antitoxin system toxin YacB | - |
| NWH85_RS24300 (46339) | 46339..48090 | - | 1752 | Protein_42 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| NWH85_RS24305 (48094) | 48094..48486 | + | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| NWH85_RS24310 (48624) | 48624..49508 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| NWH85_RS24315 (49540) | 49540..50739 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| NWH85_RS24320 (50845) | 50845..51495 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| NWH85_RS24325 (51527) | 51527..51769 | - | 243 | WP_000844627.1 | transposase | - |
| NWH85_RS24330 (51827) | 51827..53341 | - | 1515 | Protein_48 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| NWH85_RS24335 (53407) | 53407..54111 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NWH85_RS24340 (54414) | 54414..55289 | + | 876 | WP_001617865.1 | Beta-lactamase CTX-M-97 | ARG |
| NWH85_RS24345 (55324) | 55324..55641 | + | 318 | Protein_51 | IS5/IS1182 family transposase | - |
| NWH85_RS24350 (55901) | 55901..56317 | + | 417 | WP_014839980.1 | Glutathione transferase FosA | ARG |
| NWH85_RS24355 (56322) | 56322..56840 | - | 519 | WP_014839979.1 | FidL-like protein | - |
| NWH85_RS24360 (56840) | 56840..57586 | - | 747 | WP_071448054.1 | winged helix-turn-helix domain-containing protein | - |
| NWH85_RS24365 (57592) | 57592..58296 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NWH85_RS24370 (58410) | 58410..59186 | + | 777 | WP_001199192.1 | SPbeta prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| NWH85_RS24375 (59415) | 59415..60315 | + | 901 | Protein_57 | phosphotransferase | - |
| NWH85_RS24380 (60390) | 60390..60629 | + | 240 | Protein_58 | AAC(3) family N-acetyltransferase | - |
| NWH85_RS24385 (60737) | 60737..61489 | - | 753 | WP_000602738.1 | IS6 family transposase ISRle7 | Transposase |
| NWH85_RS24390 (61551) | 61551..63074 | + | 1524 | Protein_60 | Tn3 family transposase TnpA_ISRsp12 | Transposase |
| NWH85_RS24395 (63134) | 63134..63262 | + | 129 | WP_032073144.1 | hypothetical protein | - |
| NWH85_RS24400 (63300) | 63300..63785 | + | 486 | WP_006581703.1 | hypothetical protein | - |
| NWH85_RS24410 (65162) | 65162..65977 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| NWH85_RS24415 (66064) | 66064..66306 | + | 243 | Protein_65 | phosphoglucosamine mutase | - |
| NWH85_RS24420 (66542) | 66542..68035 | - | 1494 | WP_015344975.1 | IS91 family transposase ISVsa3 | Transposase |
| NWH85_RS24425 (68147) | 68147..68452 | - | 306 | WP_001255015.1 | HTH-type transcriptional regulator HdfR | VF |
| NWH85_RS24430 (68480) | 68480..69694 | - | 1215 | WP_000214122.1 | Bicyclomycin resistance protein | ARG |
| NWH85_RS24435 (69911) | 69911..70795 | - | 885 | WP_001447541.1 | DUF3363 domain-containing protein | - |
| NWH85_RS24440 (70826) | 70826..71656 | - | 831 | Protein_70 | IS91 family transposase ISVsa3 | Transposase |
| NWH85_RS24445 (71720) | 71720..72424 | + | 705 | WP_001067784.1 | IS6 family transposase IS1006 | Transposase |
| NWH85_RS24450 (72509) | 72509..72985 | - | 477 | WP_223171565.1 | hypothetical protein | - |
| NWH85_RS24455 (72919) | 72919..75870 | - | 2952 | WP_015344976.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| NWH85_RS24460 (75873) | 75873..76256 | - | 384 | Protein_74 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| NWH85_RS24465 (76309) | 76309..77013 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NWH85_RS24470 (77316) | 77316..78176 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| NWH85_RS24475 (78326) | 78326..78424 | - | 99 | Protein_77 | IS1 family transposase | - |
| NWH85_RS24480 (78453) | 78453..79763 | - | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| NWH85_RS24485 (80048) | 80048..80449 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| NWH85_RS24490 (80382) | 80382..80639 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| NWH85_RS24495 (80732) | 80732..81040 | - | 309 | WP_226116723.1 | CPBP family intramembrane metalloprotease | - |
| NWH85_RS24500 (80982) | 80982..81374 | - | 393 | WP_000616804.1 | histidine phosphatase family protein | - |
| NWH85_RS24505 (82313) | 82313..83170 | - | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| NWH85_RS24510 (83163) | 83163..83645 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| NWH85_RS24515 (83638) | 83638..83685 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| NWH85_RS24520 (83676) | 83676..83927 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| NWH85_RS24525 (83944) | 83944..84201 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| NWH85_RS24530 (84485) | 84485..84634 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (84678) | 84678..84739 | + | 62 | NuclAT_2 | - | Antitoxin Detail |
| - (84678) | 84678..84739 | + | 62 | NuclAT_2 | - | Antitoxin Detail |
| - (84678) | 84678..84739 | + | 62 | NuclAT_2 | - | Antitoxin Detail |
| - (84678) | 84678..84739 | + | 62 | NuclAT_2 | - | Antitoxin Detail |
| NWH85_RS24535 (84995) | 84995..85069 | - | 75 | Protein_89 | endonuclease | - |
| NWH85_RS24540 (85315) | 85315..85527 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| NWH85_RS24545 (85663) | 85663..86223 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| NWH85_RS24550 (86326) | 86326..87186 | - | 861 | WP_000704514.1 | Quorum-quenching protein AidA | VF |
| NWH85_RS24555 (87245) | 87245..87991 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| NWH85_RS24560 (88011) | 88011..93281 | - | 5271 | WP_000986962.1 | Multifunctional conjugation protein TraI | Relaxase |
| NWH85_RS24565 (93363) | 93363..93590 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| NWH85_RS24570 (93590) | 93590..93988 | + | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| NWH85_RS24575 (93997) | 93997..96150 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| NWH85_RS24580 (96403) | 96403..97134 | - | 732 | WP_023565183.1 | conjugal transfer complement resistance protein TraT | - |
| NWH85_RS24585 (97166) | 97166..97663 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| NWH85_RS24590 (97679) | 97679..100501 | - | 2823 | WP_001007018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| NWH85_RS24595 (100498) | 100498..101871 | - | 1374 | WP_001517790.1 | conjugal transfer pilus assembly protein TraH | - |
| NWH85_RS24600 (101871) | 101871..102251 | - | 381 | WP_001389370.1 | F-type conjugal transfer protein TrbF | - |
| NWH85_RS24605 (102238) | 102238..102579 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| NWH85_RS24610 (102509) | 102509..103054 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| NWH85_RS24615 (103041) | 103041..103325 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| NWH85_RS24620 (103406) | 103406..103720 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| NWH85_RS24625 (103722) | 103722..104069 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| NWH85_RS24630 (104085) | 104085..104828 | - | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| NWH85_RS24635 (104821) | 104821..105078 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| NWH85_RS24640 (105105) | 105105..106913 | - | 1809 | WP_000821841.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| NWH85_RS24645 (106910) | 106910..107548 | - | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| NWH85_RS24650 (107557) | 107557..108549 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| NWH85_RS24655 (108546) | 108546..109178 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| NWH85_RS24660 (109175) | 109175..109561 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| NWH85_RS24665 (109558) | 109558..112185 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| NWH85_RS24670 (112345) | 112345..112566 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| NWH85_RS24675 (112701) | 112701..113216 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| NWH85_RS24680 (113213) | 113213..113464 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| NWH85_RS24685 (113476) | 113476..113673 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| NWH85_RS24690 (113660) | 113660..114250 | - | 591 | WP_001376242.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| NWH85_RS24695 (114240) | 114240..115667 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| NWH85_RS24700 (115667) | 115667..116395 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| NWH85_RS24705 (116382) | 116382..116948 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| NWH85_RS24710 (116970) | 116970..117281 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| NWH85_RS24715 (117296) | 117296..117661 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| NWH85_RS24720 (117694) | 117694..118095 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| NWH85_RS24725 (118188) | 118188..118877 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| NWH85_RS24730 (119064) | 119064..119447 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| NWH85_RS24735 (119768) | 119768..120370 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| NWH85_RS24740 (120667) | 120667..121488 | - | 822 | WP_001234426.1 | DUF932 domain-containing protein | - |
| NWH85_RS24745 (121606) | 121606..121893 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| NWH85_RS24750 (121918) | 121918..122124 | - | 207 | WP_000547968.1 | hypothetical protein | - |
| NWH85_RS24755 (122194) | 122194..122366 | + | 173 | Protein_133 | hypothetical protein | - |
| NWH85_RS24760 (122364) | 122364..122594 | - | 231 | WP_071586998.1 | hypothetical protein | - |
| NWH85_RS24765 (122814) | 122814..122939 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| NWH85_RS24770 (122881) | 122881..123030 | - | 150 | Protein_136 | plasmid maintenance protein Mok | - |
| - (123016) | 123016..123047 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (123016) | 123016..123047 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (123016) | 123016..123047 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (123016) | 123016..123047 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (124489) | 124489..124686 | - | 198 | NuclAT_0 | - | - |
| - (124489) | 124489..124686 | - | 198 | NuclAT_0 | - | - |
| - (124489) | 124489..124686 | - | 198 | NuclAT_0 | - | - |
| - (124489) | 124489..124686 | - | 198 | NuclAT_0 | - | - |
| NWH85_RS24780 (124498) | 124498..124686 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| NWH85_RS24785 (124655) | 124655..125417 | - | 763 | Protein_139 | plasmid SOS inhibition protein A | - |
| NWH85_RS24790 (125414) | 125414..125848 | - | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| NWH85_RS24795 (125903) | 125903..126100 | - | 198 | Protein_141 | hypothetical protein | - |
| NWH85_RS24800 (126128) | 126128..126361 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| NWH85_RS24805 (126429) | 126429..126968 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| NWH85_RS24810 (126994) | 126994..127200 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| NWH85_RS24815 (127270) | 127270..127350 | + | 81 | Protein_145 | hypothetical protein | - |
| NWH85_RS24820 (127533) | 127533..127702 | - | 170 | Protein_146 | hypothetical protein | - |
| NWH85_RS24825 (128339) | 128339..129310 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| NWH85_RS24830 (129310) | 129310..130476 | - | 1167 | WP_001238646.1 | hypothetical protein | VF |
| NWH85_RS24840 (131958) | 131958..134159 | - | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| NWH85_RS24845 (134185) | 134185..135518 | - | 1334 | Protein_151 | L-lysine N6-monooxygenase | VF |
| NWH85_RS24850 (135515) | 135515..137257 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| NWH85_RS24855 (137257) | 137257..138204 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| NWH85_RS24860 (138205) | 138205..139929 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| NWH85_RS24865 (140065) | 140065..141258 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| NWH85_RS24870 (141638) | 141638..142018 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| NWH85_RS24875 (142359) | 142359..142772 | - | 414 | Protein_157 | phosphopyruvate hydratase | - |
| NWH85_RS24880 (142770) | 142770..143027 | + | 258 | Protein_158 | transposase | - |
| NWH85_RS24885 (143261) | 143261..144118 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| NWH85_RS24890 (144115) | 144115..144972 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| NWH85_RS24895 (144969) | 144969..145796 | - | 828 | WP_000983710.1 | Manganese transport system ATP-binding protein MntB | VF |
| NWH85_RS24900 (145796) | 145796..146710 | - | 915 | WP_000949004.1 | putative periplasmic iron-binding protein | VF |
| NWH85_RS24905 (147066) | 147066..147763 | + | 698 | WP_103215986.1 | IS1-like element IS1A family transposase | - |
| NWH85_RS24910 (147943) | 147943..148467 | - | 525 | Protein_164 | DUF4113 domain-containing protein | - |
| NWH85_RS24915 (148528) | 148528..148632 | - | 105 | Protein_165 | AAA family ATPase | - |
| NWH85_RS24920 (148634) | 148634..148957 | - | 324 | Protein_166 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|