MGE detailed information
MGE type: Conjugative plasmid MGE length: 129083 bp
Accession: NZ_CP101916 Location: 1..129083 Organism: Escherichia coli strain Evo1 Replicon: plasmid pEcFELIX705.1
Accession: NZ_CP101916 Location: 1..129083 Organism: Escherichia coli strain Evo1 Replicon: plasmid pEcFELIX705.1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NP443_RS22655 (NP443_22625) | 1..858 | + | 858 | WP_000130961.1 | incFII family plasmid replication initiator RepA | - |
| NP443_RS22660 (NP443_22630) | 1560..1700 | + | 141 | WP_160784086.1 | hypothetical protein | - |
| NP443_RS22665 (NP443_22635) | 1773..2042 | + | 270 | WP_000079938.1 | type II toxin-antitoxin system antitoxin YacA | Antitoxin Detail |
| NP443_RS22670 (NP443_22640) | 2042..2269 | + | 228 | WP_250694196.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| NP443_RS22675 (NP443_22645) | 2587..2723 | + | 137 | Protein_4 | IS5 family transposase IS903 | Transposase |
| NP443_RS22680 (NP443_22650) | 2805..3501 | - | 697 | Protein_5 | IS1 family transposase | - |
| NP443_RS22685 (NP443_22655) | 3680..4648 | - | 969 | WP_256692679.1 | IS5 family transposase IS903B | Transposase |
| NP443_RS22690 (NP443_22660) | 4689..4982 | - | 294 | WP_256692680.1 | biofilm development regulator YmgB/AriR family protein | - |
| NP443_RS22695 (NP443_22665) | 5298..5995 | + | 698 | WP_256692681.1 | IS1 family transposase IS1R | Transposase |
| NP443_RS22700 (NP443_22670) | 6063..6167 | - | 105 | Protein_9 | IS3 family transposase | - |
| NP443_RS22705 (NP443_22675) | 6448..9426 | - | 2979 | Protein_10 | Tn3 family transposase TnpA_TnEc1 | Transposase |
| NP443_RS22710 (NP443_22680) | 9594..10235 | + | 642 | WP_001541955.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| NP443_RS22715 (NP443_22685) | 10342..10743 | - | 402 | WP_104677271.1 | ester cyclase | - |
| NP443_RS22720 (NP443_22690) | 10752..11741 | - | 990 | WP_256692682.1 | HTH-type transcriptional regulator CdhR | VF |
| NP443_RS22725 (NP443_22695) | 11757..12533 | - | 777 | WP_022631027.1 | MBL fold metallo-hydrolase | - |
| NP443_RS22730 (NP443_22700) | 12908..13771 | - | 864 | Protein_15 | IS3 family transposase ISCfr6 | Transposase |
| NP443_RS22735 (NP443_22705) | 13811..16708 | - | 2898 | WP_087825204.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| NP443_RS22740 (NP443_22710) | 16803..17408 | + | 606 | WP_104209005.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| NP443_RS22745 (NP443_22715) | 17442..17935 | - | 494 | Protein_18 | IS3 family transposase ISEc15 | Transposase |
| NP443_RS22750 (NP443_22720) | 18139..18555 | - | 417 | WP_000754566.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| NP443_RS22755 (NP443_22725) | 18552..18782 | - | 231 | WP_001261276.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| NP443_RS22760 (NP443_22730) | 19356..19706 | + | 351 | WP_000493378.1 | hypothetical protein | - |
| NP443_RS22765 (NP443_22735) | 19757..20500 | + | 744 | WP_000129823.1 | hypothetical protein | - |
| NP443_RS22770 (NP443_22740) | 20497..21273 | + | 777 | WP_000015958.1 | site-specific integrase | - |
| NP443_RS22775 (NP443_22745) | 21331..21588 | - | 258 | WP_000764642.1 | hypothetical protein | - |
| NP443_RS22780 (NP443_22750) | 21717..21821 | - | 105 | WP_032409716.1 | hypothetical protein | - |
| NP443_RS22785 (NP443_22755) | 22351..23217 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| NP443_RS22790 (NP443_22760) | 23394..23663 | - | 270 | WP_000339857.1 | hypothetical protein | - |
| NP443_RS22795 (NP443_22765) | 24078..25283 | + | 1206 | WP_000368714.1 | AAA family ATPase | - |
| NP443_RS22800 (NP443_22770) | 25283..26257 | + | 975 | WP_000064119.1 | ParB family protein | - |
| NP443_RS22805 (NP443_22775) | 26339..27610 | - | 1272 | WP_000457559.1 | Y-family DNA polymerase | - |
| NP443_RS22810 (NP443_22780) | 27610..28041 | - | 432 | WP_000776034.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| NP443_RS22815 (NP443_22785) | 28447..29934 | + | 1488 | Protein_32 | group II intron reverse transcriptase/maturase | - |
| NP443_RS22820 (NP443_22790) | 30086..30783 | + | 698 | WP_223229472.1 | IS1 family transposase IS1X3 | Transposase |
| NP443_RS22825 (NP443_22795) | 30793..31101 | + | 309 | Protein_34 | replication initiation protein | - |
| NP443_RS22830 (NP443_22800) | 32467..33435 | + | 969 | WP_030005799.1 | IS5 family transposase IS903B | Transposase |
| NP443_RS22835 (NP443_22805) | 33575..33961 | - | 387 | WP_001039464.1 | plasmid stabilization protein StbA | - |
| NP443_RS22840 (NP443_22810) | 34542..35087 | + | 546 | Protein_37 | IS5 family transposase IS903B | Transposase |
| NP443_RS22845 (NP443_22815) | 35123..38128 | - | 3006 | WP_001143760.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| NP443_RS22850 (NP443_22820) | 38292..38849 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| NP443_RS22855 (NP443_22825) | 39032..39892 | + | 861 | WP_038976851.1 | Beta-lactamase TEM | ARG |
| NP443_RS22860 (NP443_22830) | 40291..40929 | - | 639 | WP_038976852.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| NP443_RS22865 (NP443_22835) | 41215..41835 | + | 621 | WP_000864791.1 | ParA family protein | - |
| NP443_RS22870 (NP443_22840) | 41887..42117 | + | 231 | WP_000051064.1 | plasmid partition protein ParG | - |
| NP443_RS22875 (NP443_22845) | 42133..42426 | + | 294 | WP_015060510.1 | hypothetical protein | - |
| NP443_RS22880 (NP443_22850) | 42428..43396 | + | 969 | WP_077249520.1 | IS5 family transposase IS903B | Transposase |
| NP443_RS22885 (NP443_22855) | 43456..43809 | - | 354 | WP_000876434.1 | DNA distortion polypeptide 3 | - |
| NP443_RS22890 (NP443_22860) | 43946..44392 | - | 447 | WP_001074386.1 | hypothetical protein | - |
| NP443_RS22895 (NP443_22865) | 44432..45268 | - | 837 | WP_001050931.1 | RepB family plasmid replication initiator protein | - |
| NP443_RS22900 (NP443_22870) | 46524..46775 | + | 252 | WP_000121743.1 | plasmid stabilization protein | Antitoxin Detail |
| NP443_RS22905 (NP443_22875) | 46765..47046 | + | 282 | WP_000220560.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| NP443_RS22910 (NP443_22880) | 47192..47515 | + | 324 | WP_001181903.1 | hypothetical protein | - |
| NP443_RS22915 (NP443_22885) | 47560..47805 | + | 246 | WP_000356546.1 | hypothetical protein | - |
| NP443_RS22920 (NP443_22890) | 47795..48010 | + | 216 | WP_001180116.1 | hypothetical protein | - |
| NP443_RS22925 (NP443_22895) | 48103..48432 | + | 330 | WP_000866648.1 | hypothetical protein | - |
| NP443_RS22930 (NP443_22900) | 48719..48868 | + | 150 | WP_000003880.1 | hypothetical protein | - |
| NP443_RS22935 (NP443_22905) | 48881..49153 | + | 273 | WP_000160399.1 | hypothetical protein | - |
| NP443_RS22940 (NP443_22910) | 49480..50025 | + | 546 | WP_038976855.1 | DNA distortion polypeptide 1 | - |
| NP443_RS22945 (NP443_22915) | 50028..51185 | + | 1158 | WP_000538023.1 | DNA distortion polypeptide 2 | - |
| NP443_RS22950 (NP443_22920) | 51546..52037 | + | 492 | WP_000872475.1 | transcription termination/antitermination NusG family protein | - |
| NP443_RS22955 (NP443_22925) | 52262..52906 | + | 645 | WP_000953539.1 | hypothetical protein | VF |
| NP443_RS22960 (NP443_22930) | 52890..53180 | + | 291 | WP_000921916.1 | TrbC/VirB2 family protein | - |
| NP443_RS22965 (NP443_22935) | 53204..55963 | + | 2760 | WP_000108725.1 | Type IV secretion system protein virB4 | VF |
| NP443_RS22970 (NP443_22940) | 55965..56702 | + | 738 | WP_000737859.1 | type IV secretion system protein | - |
| NP443_RS22975 (NP443_22945) | 56712..56972 | + | 261 | WP_001228869.1 | EexN family lipoprotein | - |
| NP443_RS22980 (NP443_22950) | 56984..58039 | + | 1056 | WP_000235774.1 | type IV secretion system protein | - |
| NP443_RS22985 (NP443_22955) | 58229..58951 | + | 723 | WP_000394570.1 | Type IV secretion system protein PtlE | VF |
| NP443_RS22990 (NP443_22960) | 58957..59886 | + | 930 | WP_000776689.1 | TrbG/VirB9 family P-type conjugative transfer protein | - |
| NP443_RS22995 (NP443_22965) | 59883..61097 | + | 1215 | WP_001295061.1 | hypothetical protein | VF |
| NP443_RS23000 (NP443_22970) | 61115..62152 | + | 1038 | WP_000217791.1 | Type IV secretion system protein PtlH | VF |
| NP443_RS23005 (NP443_22975) | 62157..63992 | + | 1836 | WP_000053826.1 | type IV secretory system conjugative DNA transfer family protein | - |
| NP443_RS23010 (NP443_22980) | 63989..64384 | + | 396 | WP_000733627.1 | cag pathogenicity island Cag12 family protein | - |
| NP443_RS23015 (NP443_22985) | 64387..64719 | + | 333 | WP_000699980.1 | hypothetical protein | - |
| NP443_RS23020 (NP443_22990) | 64962..65777 | + | 816 | WP_000018321.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| NP443_RS23025 (NP443_22995) | 65931..66842 | - | 912 | Protein_74 | C45 family peptidase | - |
| NP443_RS23030 (NP443_23000) | 66986..67072 | + | 87 | Protein_75 | micrococcal nuclease | - |
| NP443_RS23035 (NP443_23005) | 67487..67732 | + | 246 | WP_001243650.1 | hypothetical protein | - |
| NP443_RS23040 (NP443_23010) | 67752..70076 | + | 2325 | WP_001235773.1 | type IA DNA topoisomerase | - |
| NP443_RS23045 (NP443_23015) | 70088..70537 | + | 450 | WP_256692664.1 | H-NS family nucleoid-associated regulatory protein | - |
| NP443_RS23050 (NP443_23020) | 70600..71004 | + | 405 | WP_000059893.1 | hypothetical protein | - |
| NP443_RS23055 (NP443_23025) | 71159..74023 | - | 2865 | Protein_80 | Tn3 family transposase TnpA_Tn3 | Transposase |
| NP443_RS23060 (NP443_23030) | 74070..74774 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| NP443_RS23065 (NP443_23035) | 74839..75345 | + | 507 | Protein_82 | transposase | - |
| NP443_RS23070 (NP443_23040) | 75762..76652 | + | 891 | WP_223151485.1 | alpha/beta fold putative hydrolase EstX | - |
| NP443_RS23075 (NP443_23045) | 76741..77579 | + | 839 | Protein_84 | Streptomycin 3''-adenylyltransferase | ARG |
| NP443_RS23080 (NP443_23050) | 77702..78034 | + | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| NP443_RS23085 (NP443_23055) | 78281..78913 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| NP443_RS23090 (NP443_23060) | 78936..79211 | + | 276 | WP_109023896.1 | hypothetical protein | - |
| NP443_RS23095 (NP443_23065) | 79214..80005 | - | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| NP443_RS23100 (NP443_23070) | 80474..80719 | - | 246 | WP_001354008.1 | GrpB family protein | - |
| NP443_RS23105 (NP443_23075) | 80757..81620 | - | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| NP443_RS23110 (NP443_23080) | 81766..82023 | - | 258 | Protein_91 | hypothetical protein | - |
| NP443_RS23115 (NP443_23085) | 82078..82782 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NP443_RS23120 (NP443_23090) | 82847..84322 | + | 1476 | WP_202764053.1 | hypothetical protein | Relaxase |
| NP443_RS23125 (NP443_23095) | 84547..84894 | + | 348 | WP_038988888.1 | hypothetical protein | - |
| NP443_RS23130 (NP443_23100) | 84909..84974 | + | 66 | Protein_95 | EAL domain-containing protein | - |
| NP443_RS23135 (NP443_23105) | 85114..85287 | - | 174 | Protein_96 | IS6 family transposase | - |
| NP443_RS23140 (NP443_23110) | 85289..85750 | - | 462 | WP_196451626.1 | DMT family transporter | - |
| NP443_RS23145 (NP443_23115) | 85852..86649 | - | 798 | Protein_98 | Tn3 family transposase TnpA_IS3000 | Transposase |
| NP443_RS23150 (NP443_23120) | 86702..87286 | - | 585 | Protein_99 | IS6-like element IS26 family transposase | - |
| NP443_RS23155 (NP443_23125) | 87339..88043 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| NP443_RS23160 (NP443_23130) | 88196..89017 | - | 822 | WP_000939727.1 | hypothetical protein | ARG |
| NP443_RS23165 (NP443_23135) | 89102..89940 | - | 839 | Protein_102 | Streptomycin 3''-adenylyltransferase | ARG |
| NP443_RS23170 (NP443_23140) | 90089..90886 | + | 798 | Protein_103 | IS91 family transposase ISMno23 | Transposase |
| NP443_RS23175 (NP443_23145) | 90939..91643 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| NP443_RS23180 (NP443_23150) | 91702..92043 | + | 342 | WP_256692665.1 | replication initiation protein | - |
| NP443_RS23185 (NP443_23155) | 94000..94386 | - | 387 | WP_256692666.1 | Tn3 family transposase TnpR_TnShfr1 | Transposase |
| NP443_RS23190 (NP443_23160) | 94363..95067 | + | 705 | WP_001067858.1 | Tn3 family transposase TnpR_TnShfr1 | Transposase |
| NP443_RS23195 (NP443_23165) | 95121..95615 | - | 495 | Protein_108 | IS4 family transposase IS10R | Transposase |
| NP443_RS23200 (NP443_23170) | 95758..96618 | + | 861 | WP_000557454.1 | SPbeta prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| NP443_RS23205 (NP443_23175) | 96631..97173 | + | 543 | WP_000587837.1 | AAA family ATPase | - |
| NP443_RS23210 (NP443_23180) | 97710..98414 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| NP443_RS23215 (NP443_23185) | 98360..98857 | - | 498 | WP_256692667.1 | replication initiation protein | - |
| NP443_RS23220 (NP443_23190) | 99417..99758 | + | 342 | WP_000057569.1 | antirestriction protein ArdAB regulator ArdK | - |
| NP443_RS23225 (NP443_23195) | 99773..100135 | - | 363 | WP_241281442.1 | hypothetical protein | - |
| NP443_RS23230 (NP443_23200) | 100161..100337 | + | 177 | Protein_115 | alpha/beta hydrolase | - |
| NP443_RS23235 (NP443_23205) | 100404..100829 | - | 426 | WP_256692668.1 | FosA8 family fosfomycin resistance glutathione transferase | - |
| NP443_RS23240 (NP443_23210) | 100943..101647 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| NP443_RS23245 (NP443_23215) | 101691..101825 | + | 135 | Protein_118 | ParA family protein | - |
| NP443_RS23250 (NP443_23220) | 101822..102787 | + | 966 | WP_000725192.1 | ParB family protein | - |
| NP443_RS23255 (NP443_23225) | 103052..104748 | + | 1697 | Protein_120 | hypothetical protein | - |
| NP443_RS23260 (NP443_23230) | 104809..106398 | + | 1590 | WP_256692669.1 | hypothetical protein | - |
| NP443_RS23265 (NP443_23235) | 106408..107223 | + | 816 | WP_000041756.1 | hypothetical protein | - |
| NP443_RS23270 (NP443_23240) | 107295..107540 | + | 246 | Protein_123 | IS3 family transposase ISEhe3 | Transposase |
| NP443_RS23275 (NP443_23245) | 107609..108760 | + | 1152 | WP_256692670.1 | IS30 family transposase IS30D | Transposase |
| NP443_RS23280 (NP443_23250) | 108770..109456 | + | 687 | Protein_125 | IS3 family transposase ISEhe3 | Transposase |
| NP443_RS23285 (NP443_23255) | 109513..110210 | + | 698 | WP_256692671.1 | IS1 family transposase IS1S | Transposase |
| NP443_RS23290 (NP443_23260) | 110229..110648 | + | 420 | WP_256692672.1 | hypothetical protein | - |
| NP443_RS23295 (NP443_23265) | 110903..112402 | + | 1500 | WP_256692673.1 | IS21 family transposase ISEc10 | Transposase |
| NP443_RS23300 (NP443_23270) | 112399..113154 | + | 756 | WP_000065240.1 | IS21 family transposase ISEc10 | Transposase |
| NP443_RS23305 (NP443_23275) | 113592..115163 | - | 1572 | WP_256692674.1 | IS66 family transposase ISCro1 | Transposase |
| NP443_RS23310 (NP443_23280) | 115183..115530 | - | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| NP443_RS23315 (NP443_23285) | 115530..116207 | - | 678 | Protein_132 | IS66 family transposase ISCro1 | Transposase |
| NP443_RS23320 (NP443_23290) | 116323..117351 | - | 1029 | WP_256692675.1 | tyrosine-type recombinase/integrase | - |
| NP443_RS23330 (NP443_23300) | 118452..118850 | - | 399 | WP_256692677.1 | hypothetical protein | - |
| NP443_RS23335 (NP443_23305) | 119007..119495 | - | 489 | WP_015060468.1 | isochorismatase family protein | - |
| NP443_RS23340 (NP443_23310) | 119662..120866 | - | 1205 | Protein_137 | MFS transporter | - |
| NP443_RS23345 (NP443_23315) | 121031..121735 | - | 705 | WP_001067848.1 | IS6-like element IS26 family transposase | - |
| NP443_RS23350 (NP443_23320) | 121798..122925 | + | 1128 | Protein_139 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| NP443_RS23355 (NP443_23325) | 122983..123225 | + | 243 | WP_000844627.1 | transposase | - |
| NP443_RS23360 (NP443_23330) | 123257..123907 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| NP443_RS23365 (NP443_23335) | 124013..125212 | + | 1200 | WP_000804064.1 | tetracycline efflux MFS transporter Tet(A) | - |
| NP443_RS23370 (NP443_23340) | 125244..125978 | - | 735 | WP_042098113.1 | EamA family transporter | - |
| NP443_RS23375 (NP443_23345) | 126322..126999 | - | 678 | WP_040064606.1 | D-allulose-6-phosphate 3-epimerase | VF |
| NP443_RS23380 (NP443_23350) | 126996..127334 | - | 339 | WP_256692678.1 | hypothetical protein | - |
| NP443_RS23385 (NP443_23355) | 127393..128097 | - | 705 | WP_001067848.1 | IS6-like element IS26 family transposase | - |
| NP443_RS23390 (NP443_23360) | 128156..128293 | + | 138 | Protein_147 | hypothetical protein | - |
| NP443_RS23395 (NP443_23365) | 128533..128793 | + | 261 | WP_000083819.1 | replication regulatory protein RepA | - |
| NP443_RS23400 (NP443_23370) | 128887..129071 | + | 185 | Protein_149 | protein CopA/IncA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|